A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75. by Stephen Hare, Ming-Chieh Shun, Saumya Shree Gupta, Eugene Valkov, Alan Engelman, Peter Cherepanov

“…Furthermore, the new structural details enabled us to engineer a mutant of HIV-1 IN that primarily functions only when presented with a complementary LEDGF mutant. …”
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Organization of controlling innovations in an industrial enterprise management by A. R. Khachemizov

“…As a result of the research, a scheme has been created representing the role of controlling as an element of feedback in an enterprise system, a description of the main controlling functions as an industrial enterprise management subsystem has been presented, and the role of controlling in the implementation of innovative project management processes has been clarified. …”
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Influence of a laser pulse on thermoelasticity with temperature dependence under the dual-phase-lag model using improved modified extended tanh function method by Wafaa B. Rabie, Hamdy M. Ahmed, Abdallah A. Syied, Assmaa Abd-Elmonem, Nagat A.A. Suoliman, Mohamed F. Ismail

“…In this paper, the improved modified extended tanh function method (IMETFM) is introduced for analyzing the influence of laser pulse on a thermo-elastic with temperature-dependence under a dual phase lag model (DPL). …”
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Effects of Resveratrol on Liver Function Tests in Patients with Non-Alcoholic Fatty Liver Disease: a Systematic Review and Meta-Analysis of Randomized Controlled Trials by P. Ebrahimpour, M. Karamian, A. Sharifi

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Functionalized Fe3O4 Magnetic Nanoparticle Potentiometric Detection Strategy versus Classical Potentiometric Strategy for Determination of Chlorpheniramine Maleate and Pseudoephedr... by Azza A. Moustafa, Maha A. Hegazy, Dalia Mohamed, Omnia Ali

“…Nanosized adsorbents when used in potentiometric methods of analysis usually show better performance rather than the traditional potentiometric approach; this is attributed to the high specific surface area of the nanomaterial used in addition to the lack of internal diffusion resistance, thus improving their adsorption capacity. In the presented work, a rapid and sensitive potentiometric determination of chlorpheniramine maleate (CPM) and pseudoephedrine hydrochloride (PSE) in pure form, in pharmaceutical preparation, and in biological fluid was developed based on functionalized magnetic nanoparticles (Fe3O4). …”
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Short-term functional outcomes and treatment trends for branch atheromatous disease and lacunar infarction: a retrospective cohort study of a nationwide multicenter registry by Gaku Fujiwara, Hideki Oka, Akihiro Fujii

“…Moreover, aggressive treatment strategies, including the use of argatroban and dual antiplatelet therapy, were more common in BAD patients. Conclusion BAD presented worse functional outcomes and longer hospital stays than LI, necessitating treatment plans that take into account its progression and prognosis.…”
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Evaluation of the condylar position in subjects with signs and symptoms of functional disorders of the temporomandibular joint through images made with cone beam computed tomograph... by Marcelo Oliveira Mazzetto, Giovana Cherubini Veneziam, Laís Valencise Magri, Mario Kaissar Nasr, Alexandra Faria Paiva, Guiovaldo Paiva

“… ABSTRACT: The aim of the study was to investigate the condylar position within the articular cavity in patients with temporomandibular disorders with signs and symptoms of functional articular disorders through images made with cone beam computed tomography (CBCT) on the sagittal plane. …”
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Rational Possibility of Generating Power Laws in the Synthesis of Cam Mechanisms by B. I. Paleva-Kadiyska, R. А. Roussev, V. В. Galabov

“…Results.A unified formula for determining the values of coefficients, which gives correct results for any number of even and/or odd exponents, is presented. The correctness of the derived formula is validated by the results on the multiple checks for different numbers, even and odd values of the exponents of quinquinomial and hexanomial power functions.  …”
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MATHEMATICAL MODELING AND EXPERIMENTAL STUDIES OF MEMBRANE CONCENTRATION IN APPARATUSES WITH THE WITHDRAWAL OF THE POLARIZATION LAYER by Lobasenko B.A., Sazonova E.K., Musaev P.A., Pachkin S.G.

“…A technique for calculating the transfer function of a system is described. Comparative evaluation of the values obtained using the given model and the experimental values of the industrial pilot membrane apparatus have been done. …”
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Successful cryopreservation of marine invertebrates immune cells enables long-term studies of common octopus, Octopus vulgaris Cuvier 1797, hemocyte immune functions by María M. Costa, Estefania Paredes, Mercedes Peleteiro, Lucía Sánchez-Ruiloba, Francisco Gambón, Sonia Dios, Camino Gestal

“…The acclimation process after thawing was essential to recover the functional activity of the cells and to return to levels of gene expression involved in oxidative stress similar to fresh cells.The results presented here will facilitate functional studies of octopus immune cells and provide tools for cell preservation in other molluscs species.…”
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Mannan-oligosaccharide modulates gut microbiota and enhances immune-metabolic functions in Chinese mitten crab (Eriocheir sinensis): Insights from an in vitro fermentation model by Wei Li, Shubin Liu, Kaiqi Huang, Xiaoling Zhang, Xiaodan Wang, Jian G. Qin, Liqiao Chen, Erchao Li

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Can Ecosystem Transformations by Non-Indigenous Mussel Introductions Inform Shellfish Reef Restoration? by Alan Cottingham, Rachel Newsome, Chris Gillies, James R. Tweedley

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Resepsi Fungsional Surah Al-Fātiḥaḥ di Kalangan Disabilitas Sensorik Rungu Wicara Rumah Qur’an Sahabat Tuli Asy-Syukur Kediri by Faricha Cahya Fajrianti, Kholila Mukaromah

“…This article aims to understand more deeply how surah Al-Fātiḥaḥ is perceived and functioned practically by people with hearing and speech sensory disabilities (PDSRW) at the Qur'an House of the Deaf Friends Asy-Syukur Kediri. …”
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Effectiveness of predictive scoring systems in predicting mortality in relation to baseline kidney function in adult intensive care unit patients: a systematic review protocol by Greg Knoll, Ayub Akbari, Risa Shorr, Edward G Clark, Gregory L Hundemer, Amos Buh, Hajar El Wadia, Abdulghani Omar Kabli, Marisha Karim, Nandini Biyani, Inok Lee

“…Results will be disseminated through publication in a peer-reviewed journal and will also be presented at seminars and conferences.PROSPERO registration number CRD42024611547.…”
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Exploring Adsorption Performance of Functionalized Mesoporous Silicas with a Different Pore Structure as Strong Cation-Exchange Sorbents for Solid-Phase Extraction of Atropine and... by Fernando L. Vera-Baquero, Sonia Morante-Zarcero, Damián Pérez-Quintanilla, Isabel Sierra

“…In this work, mesoporous silicas with two types of mesoporous structures were synthesized and functionalized with sulfonic acid groups: MCM-41-SO₃H (honeycomb-like hexagonal structure) and MSU-2-SO₃H (three-dimensional porous structure with wormhole pores). …”
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Optical Coherence Tomography Predictors of Favorable Functional Response in Naïve Diabetic Macular Edema Eyes Treated with Dexamethasone Implants as a First-Line Agent by Alessandro Meduri, Giovanni William Oliverio, Luigi Trombetta, Marta Giordano, Leandro Inferrera, Costantino John Trombetta

“…Furthermore, there were statistically significant changes in CRT, IRC, HRS, and SRD. Nineteen patients presented a  >10-letters improvement in BCVA; the presence of SRD at baseline was a predictor of good functional treatment response at 12 months (OR 2.1; 95% C.I. 1.2–4.9; p=0.001) as well as the presence of EZ integrity preoperatively (OR 1.3; 95% C.I. 0.5–2.4; p=0.001) and the absence of vitreoretinal interface alteration (OR 1.1; 95% C.I. 0.3–2.3; p=0.02). …”
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Effect of Slow Deep Breathing on Lung Function Among Individuals with Multi-Drug-Resistant Tuberculosis (MDR-TB) at a Regional General Hospital in Indonesia by Nur Hafizah, Widiharti Widiharti, Widya Lita Fitrianur, Ernawati Ernawati

“…Results: The results showed of 19 (54.3%) and almost half of participants had abnormal lung function, 16 (45.7%) people. After being given intervention, the majority of particupants presented normal lung function, 21 (65.7%) of them and almost half of them had abnormal lung function, 12 (34.3%) of them. …”
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Validity and Feasibility of the Seated Medicine Ball Throw and Unilateral Shot-Put Tests in Assessing Upper Extremity Function in Rotator-Cuff-Related Shoulder Pain by Michal Linkovski, Jeremy Lewis, Hilla Sarig Bahat

“…<b>Background:</b> Rotator cuff-related shoulder pain (RCRSP) is a common musculoskeletal condition characterized by pain, functional disability, reduced mobility, and weakness. …”
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Relationship Between Resting-State Functional Magnetic Resonance Imaging and Different Time in Target Glucose Range in Elderly Patients with Type 2 Diabetes Mellitus by Yang P, Liu S, Li L

“…Decreased ALFF values in differential brain regions were significantly negatively correlated with the basal C-peptide level (p=0.007) and significantly positively correlated with the basal Mini-Mental State Examination (MMSE) score (p = 0.048).Conclusion: ReHO, ALFF, and fALFF value differences were present between the low and high TIR groups. Elderly T2DM patients in the low-TIR group were more susceptible to impaired brain function, which presented mainly as abnormal reduction in and activation of functional activity in some temporal lobes, frontal lobes, and occipital lobes in the resting state, and more significant when glycemic control is poorer.Keywords: type 2 diabetes mellitus, time in range, resting-state functional magnetic resonance imaging, low-frequency fluctuation, fractional low-frequency fluctuation, regional homogeneity…”
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Pre-procedural abnormal von Willebrand factor function predicts clinical outcomes after Transcatheter Aortic Valve Implantation: a prospective cohort study by Haitham Abu Khadija, Mohammad Alnees, Mohammad Alnees, Omar Ayyad, Gera Gandelman, Nizar Abu Hamdeh, Amir Haim, Yazan Hamdan, Ramon Cohen, Duha Najajra, Alena Kirzhner, Tal Schiller, Jacob George, Alex Blatt

“…While, patients with abnormal von Willebrand factor function presented an Coef of 1.841 (p = 0.022; 95% CI: 0.271–3.410) for complications compared to those without AVWS. …”
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