Impact of PM2.5 Exposure on Reproductive Health and Sperm Functions in Mice from a High-Pollution Industrial Environment by Fu-Jen Cheng, Chung-Shin Yuan, Xin Chen, Yu-Sheng Lin, Ping-Hsun Wu, Ping-Chi Hsu

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Microbial Community Structure and Metabolic Function in the Venom Glands of the Predatory Stink Bug, <i>Picromerus lewisi</i> (Hemiptera: Pentatomidae) by Jinmeng Li, Xu Tian, Tom Hsiang, Yuting Yang, Caihua Shi, Hancheng Wang, Wenhong Li

“…The bacterial and fungal community structure of the venom glands of <i>P. lewisi</i> exhibited high species richness and diversity, along with a strong metabolism of 22 carbon sources. Functional prediction indicated that the primary dominant function of <i>P. lewisi</i> venom-gland bacteria was metabolism. …”
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Variability in grain, flour, functional properties and protein profiling in newly developed wheat genotypes grown in temperate climate of Western Himalayas by Taha Mukhtar, Abida Jabeen, Syed Zameer Hussain, Raashid Ahmad Siddiqi, Shabir H. Wani, Anju Mahendru-Singh, Tawheed Amin, Quraazah A. Amin, Mohmad Sayeed Bhat

“…These wheat genotypes were studied for their functional, structural and protein profiling characteristics as per the approved AACC and AOAC standard methods of analysis.ResultsThe various physical parameters varied significantly (p ≤ 0.05) between wheat genotypes. …”
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Unveiling Resmetirom: A systematic review and meta‐analysis on its impact on liver function and safety in non‐alcoholic steatohepatitis treatment by Hashim Talib Hashim, Ahmed Qasim Mohammed Alhatemi, Sania Riaz, Mohammedbaqer Ali Al‐Ghuraibawi, Arwa S. Alabide, Humza Saeed, Fatimah Abdullah Sulaiman, Mustafa Ali Abd Alhussain, Maythum Ali Shallan, Ahmed Dheyaa Al‐Obaidi, Omar Saab, Hasan Al‐Obaidi, Ali Talib Hashim, Nooraldin Merza

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Diversity and plant growth-promoting functions of diazotrophic/N-scavenging bacteria isolated from the soils and rhizospheres of two species of Solanum. by Mónica Yorlady Alzate Zuluaga, Karina Maria Lima Milani, Leandro Simões Azeredo Gonçalves, André Luiz Martinez de Oliveira

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Insights into the effects of apelin-13 on renal function and NHE3 activity following ischemia/reperfusion-induced acute kidney injury by Guilherme Lopes-Gonçalves, Juliana Martins Costa-Pessoa, Mariana Charleaux de Ponte, Heitor Macedo Braz, Maria Oliveira-Souza

“…Considering the relevance of proximal tubular cells in maintaining fluid and electrolyte homeostasis, the effects of apelin-13 on tubular injury or sodium proximal transport remain unclear. Thus, the present study aims to evaluate the effects of exogenous administration of apelin-13 in the renal ischemia/reperfusion (I/R) model, with particular focus on renal function, injury markers, and tubular proliferation.MethodsMale C57BL/6 mice were initially treated with a vehicle or high dose of apelin-13 (200 μg/kg/day) and subjected to kidney bilateral ischemia procedure for 30 min or a sham surgery. …”
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Cardiac function evaluation in healthy volunteers and patients with implantable cardioverter-defibrillators using high-bandwidth spoiled gradient-echo cine by Calder D. Sheagren, Naseem Shadafny, Terenz Escartin, Maria Terricabras, Christopher C. Cheung, Idan Roifman, Graham A. Wright

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Identification and functional characterization of T-cell exhaustion-associated lncRNA AL031775.1 in osteosarcoma: a novel therapeutic target by Yameng Wang, Yameng Wang, Yameng Wang, Yameng Wang, Jinghong Yuan, Jinghong Yuan, Jinghong Yuan, Keying Guo, Keying Guo, Keying Guo, Zhuoer Zhang, Junchao Zhu, Junchao Zhu, Junchao Zhu, Shahrzad Arya, Guowen Huang, Guowen Huang, Guowen Huang, Shengqin Li, Shengqin Li, Shengqin Li, Qi Chen, Xijuan Liu, Jingyu Jia, Jingyu Jia, Jingyu Jia

“…BackgroundOsteosarcoma, an aggressive bone malignancy predominantly affecting children and adolescents, presents significant therapeutic challenges with a 5-year survival rate below 30% in metastatic cases. …”
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Functional and quality of life outcomes after partial glossectomy: a multi-institutional longitudinal study of the head and neck research network by Agnieszka Dzioba, Daniel Aalto, Georgina Papadopoulos-Nydam, Hadi Seikaly, Jana Rieger, Johan Wolfaardt, Martin Osswald, Jeffrey R. Harris, Daniel A. O’Connell, Cathy Lazarus, Mark Urken, Ilya Likhterov, Raymond L. Chai, Erika Rauscher, Daniel Buchbinder, Devin Okay, Risto-Pekka Happonen, Ilpo Kinnunen, Heikki Irjala, Tero Soukka, Juhani Laine, Head and Neck Research Network

“…Conclusions Assessment time influenced patient-reported speech, swallowing, and quality of life outcomes, while treatment (by time) effects were found for only swallowing and quality of life outcomes. Results of the present study will help guide clinical care and will be useful for patient counseling on expected short and long-term functional and quality of life outcomes of surgical and adjuvant treatment for oral cavity cancer.…”
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Prognostic Implications of Guideline-Directed Medical Therapy for Heart Failure in Functional Mitral Regurgitation: A Systematic Review and Meta-Analysis by Vasileios Anastasiou, Andreas S. Papazoglou, Stylianos Daios, Dimitrios V. Moysidis, Eirinaios Tsiartas, Matthaios Didagelos, Kyriakos Dimitriadis, Theodoros Karamitsos, George Giannakoulas, Konstantinos Tsioufis, Antonios Ziakas, Vasileios Kamperidis

“…<b>Objectives:</b> Randomized evidence on the role of heart failure guideline-directed medical therapy for patients with functional mitral regurgitation (FMR) is lacking. The present meta-analysis sought to investigate the prognostic impact of different pharmacotherapy categories recommended in heart failure on subjects with FMR. …”
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Cost-effective medium optimization and functional enhancement of Lactiplantibacillus plantarum 22F for industrial-scale probiotic production in swine feed by Nay Zin Myo, Ratchnida Kamwa, Benjamas Khurajog, Pawiya Pupa, Wandee Sirichokchatchawan, David J. Hampson, Nuvee Prapasarakul

“…Background and Aim: Industrial-scale probiotic production requires economically viable media formulations that do not compromise strain functionality. This study aimed to develop a cost-effective medium for cultivating Lactiplantibacillus plantarum 22F (L22F), a probiotic candidate isolated from swine feces, while evaluating its industrial viability and functional metabolic profile. …”
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Evaluating Impact of Surgical Myocardial Revascularization on Global Left Ventricular Systolic Function and Immediate Postoperative Outcome using Transesophageal Echocardiography by Abhijeet Shitole, Veerappa Kothiwale, Sharanagouda Patil, Preeti Lamba, Anand Vagarali, Jabbar Momin, Sweta Sooragonda, Anushri Patil

“…Transesophageal echocardiography (TEE) provides an excellent opportunity to evaluate cardiac function in operating room. Present study was aimed at evaluating impact of surgical myocardial revascularization on global LV systolic function. …”
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Genome-wide identification of five fern bHLH families and functional analysis of bHLHs in lignin biosynthesis in Alsophila spinulosa by Xiong Huang, Jiangtao Fan, Cai Liu, Peiyun Wang, Hongfei Li, Gang Wang, Xiaohong Chen

“…Additionally, tissue-specific expression patterns of AspbHLH genes suggest diverse functional roles in plant growth, development, and metabolite synthesis. …”
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Tai Chi as a mind-body exercise modulates endothelial function in coronary artery disease: A randomized clinical trial by Yameng Li, Cuihan Li, Jiansheng Wen, Meize Cui, Qiuyang Wei, Mingyu Liu, Zaihao Chen, Hui Fang, Linli Liu, Jiahao Fu, Jianwei Zhang, Shaojun Lyu

“…However, the effects of TC on endothelial function in CAD patients compared to aerobic exercise (AE) remain understudied. …”
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ID1 and ID3 functions in the modulation of the tumour immune microenvironment in adult patients with B-cell acute lymphoblastic leukaemia by Nathaly Poveda-Garavito, Nathaly Poveda-Garavito, Nathaly Poveda-Garavito, Carlos A. Orozco Castaño, Carlos A. Orozco Castaño, Yulieth Torres-Llanos, Yulieth Torres-Llanos, Yulieth Torres-Llanos, Nataly Cruz-Rodriguez, Rafael Parra-Medina, Rafael Parra-Medina, Sandra Quijano, Jovanny Zabaleta, Alba Lucia Combita, Alba Lucia Combita, Alba Lucia Combita

“…IntroductionB-cell acute lymphoblastic leukemia (B-ALL) in adults often presents a poor prognosis. ID1 and ID3 genes have been identified as predictors of poor response in Colombian adult B-ALL patients, contributing to cancer development. …”
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Sex-specific cardiometabolic multimorbidity, metabolic syndrome and left ventricular function in heart failure with preserved ejection fraction in the UK Biobank by Ambre Bertrand, Xin Zhou, Andrew Lewis, Thomas Monfeuga, Ramneek Gupta, Vicente Grau, Blanca Rodriguez

“…We examined sex-specific differences in cardiometabolic comorbidity burden and metabolic syndrome, performed latent class analysis (LCA) to identify distinct clusters of patients based on their cardiometabolic profile, and compared CMR imaging-derived parameters of left ventricular function at rest in the different clusters identified to reflect possible differences in adverse cardiac remodelling. …”
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Association of Platelet Indices with Cardiac Enzymes and Left Ventricular Function in Patients with Acute Myocardial Infarction: A Cross-sectional Study by P Kireeti, Rajesh Singh Laishram, Mayanglambam Bijoy, Sunil Kumar Leishangthem, Rajkumar Ajaykumar, Keisham Jaya Chanu, Ningthoukhongjam Reema, Dhanaraj Singh Chongtham

“…However, the association of platelet indices with cardiac enzymes and Left Ventricular (LV) function in patients with Acute Myocardial Infarction (AMI) remains unexplored. …”
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GPD2 inhibition impairs coagulation function via ROS/NF-κB/P2Y12 pathway by Jiajie Chen, Guifeng Xu, Zhipeng Xie, Shaoxia Xie, Wenwei Luo, Shilong Zhong, Weihua Lai

“…Subsequently, epigenome-wide association study (EWAS), summary data-based Mendelian randomization (SMR), and heterogeneity in dependent instruments (HEIDI) analyses were applied to pinpoint critical methylation sites that influence gene expression, platelet function recovery, and bleeding risk. After developing a targeted cellular model using the CRISPR-dCas9-DNMT3A/Tet1CD-U6-sgRNA system and integrating with transcriptomic sequencing data, we conducted mechanistic cellular experiments to elucidate how these methylation sites affect platelet function recovery and bleeding risk. …”
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Does Time and Experience Matter in Pediatric Arterial Ischemic Stroke (AIS) Intervention in Patients with an Initial Clinical Presentation of Mild/Moderate Severity? Long-Term Foll... by Gulten Ozturk, Erhan Biyikli, Olcay Unver, Omer Dogru, Evrim Karadag Saygi, Feyyaz Baltacioglu, Dilsad Turkdogan

“…Seventeen patients (53.3%) reported normal daily functions at the last visit. A younger presentation age (≤60 months) was related to a longer hospital admission duration (24 h vs. 9 h) and worse long-term functional outcomes (<i>p</i> = 0.023). …”
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On Actual Direction of Linguopoetics: Russian Conjunctions in Text Service (History of Issue) by E. A. Krasnova

“…The author considers that it is expedient to reveal the methodological mechanism of interaction of deep private meanings of conjunctive utterances in the process of their participation in creation of the conceptual meaning of a literary work equal to the author’s intention. The present study promotes the expansion of ideas about the functions of functional parts of speech in the artistic narrative, and also outlines the prospects for the study of other Russian conjunctions in the textual aspect.…”
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