Unraveling the Specific Recognition Between PD-L1 and Engineered CLP002 Functionalized Gold Nanostructures: MD Simulation Studies by Micaela Giannetti, Marina Gobbo, Lucio Litti, Isabella Caligiuri, Flavio Rizzolio, Moreno Meneghetti, Claudia Mazzuca, Antonio Palleschi

“…To determine the presence of PD-L1 in cells, the use of ad hoc functionalized peptides that bind to PD-L1 can be exploited. …”
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Electrogenic amino acid transport in the intestine of sea bream (Sparus aurata): From functional characterization to physiological effects of Lysophospholipids in aquafeeds by Rocio Robles-Arozarena, Juan Antonio Martos-Sitcha, Laura Bermúdez, Waldo Nuez-Ortín, Juan Fuentes

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The pancreatic tumor microenvironment of treatment-naïve patients causes a functional shift in γδ T cells, impairing their anti-tumoral defense by Elena Lo Presti, Francesca Cupaioli, Daniela Scimeca, Elettra Unti, Vincenzo Di Martino, Rossella Daidone, Michele Amata, Nunzia Scibetta, Erinn Soucie, Serena Meraviglia, Juan Iovanna, Nelson Dusetti, Andrea De Gaetano, Ivan Merelli, Roberto Di Mitri

“…Pancreatic ductal adenocarcinoma (PDAC) presents a unique challenge for researchers due to its late diagnosis caused by vague symptoms and lack of early detection markers. …”
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Alterations of white matter functional networks in pediatric drug-resistant temporal lobe epilepsy: A graph theory analysis study by Kexin Huang, Yuxin Xie, Haifeng Ran, Jie Hu, Yulun He, Gaoqiang Xu, Guiqin Chen, Qiane Yu, Xuhong Li, Junwei Liu, Heng Liu, Tijiang Zhang

“…This indicates that the WM functional network in DRTLE presents with anomalies in the topological attributes, which are associated with cognitive impairments. …”
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Function of HP1BP3 as a linker histone is regulated by linker histone chaperones, NPM1 and TAF-I by Miharu Hisaoka, Tetsuro Komatsu, Takuma Hashimoto, Jianhuang Lin, Yasuyuki Ohkawa, Mitsuru Okuwaki

“…The present study aimed to elucidate the function of full-length HP1BP3 as a linker histone variant. …”
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Comprehensive analysis of Mendelian randomization and scRNA-seq identify key prognostic genes and relevant functional roles in colorectal cancer by Meng Hu, Haotian Dong, Chujia Chen, Chengyuan Ye, Jianing Yan, Xuan Yu, Guoliang Ye, Yongfu Shao

“…The expression levels were confirmed by using quantitative real-time polymerase chain reaction (qRT-PCR). The biological functions and effect on prognosis of the identified prognostic genes were also explored. …”
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Comparing HeartModelAI and cardiac magnetic resonance imaging for left ventricular volume and function evaluation in patients with dilated cardiomyopathy by Mahboobeh Sheikh, Sahar Asl Fallah, Muhammadhosein Moradi, Arash Jalali, Ahmad Vakili-Basir, Mohammad Sahebjam, Haleh Ashraf, Arezou Zoroufian

“…Conclusion HeartModelAI software emerges as a rapid and viable imaging approach for evaluating the left ventricle’s structure and function. In our study, LV volumes assessed by HeartModelAI demonstrated strong correlations with cardiac magnetic resonance imaging.…”
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Regional Frequency Analysis Using L-Moments for Determining Daily Rainfall Probability Distribution Function and Estimating the Annual Wastewater Discharges by Pau Estrany-Planas, Pablo Blanco-Gómez, Juan I. Ortiz-Vallespí, Javier Orihuela-Martínez, Víctor Vilarrasa

“…The Generalized Pareto gave the best probability distribution function for the selected region, and it was used to simulate daily rainfall and system discharges over annual periods using Monte Carlo techniques. …”
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Designing a sensory, motor, and cognitive intervention program and assessing its effectiveness on the neuropsychological profile of children with high-functioning autism by azam Bahadiori, Saeed Rezaei, Parviz Sharifi Daramadi, Mohammad Asgari

“…Meanwhile, a comprehensive program that covers sensory, motor, and cognitive aspects can improve their neuropsychological profile, which has not been designed so far. Aims: The present study aimed to design a sensory, motor, and cognitive intervention program and its effectiveness on the neuropsychological profile of children with high-functioning autism. …”
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Effects of Cd exposure on peripheral blood cell population and functional changes in innate immunity of the African sharptooth catfish (Clarias gariepinus) by Edward S. Mayila, Alexanda Mzula, Cyrus Rumisha, Marc Kochzius

“…Cadmium is a naturally occurring trace metal, present in different concentrations both in sediments and biota environments with some toxic effects. …”
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Effects of Ankle Proprioceptive Training on Ankle Functionality and Performance of Recreational Badminton Players with Pronated Feet: A Quasi-experimental Study by Shivani Vyas, S Sudhakar

“…Results: The experimental groups in present study showed considerable improvement in functionality and agility when compared to the control group (p<0.05). …”
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Unraveling the structural and functional consequences of non-synonymous single-nucleotide polymorphisms (nsSNPs) in human SOCS2: an in silico approach by Tanvir Hossain, Md. Nur Islam, Md. Anwar Hossain, Md. Mofizur Rahman, Mohammed Mafizul Islam, Shipan Das Gupta

“…Multiple non-synonymous SNPs (nsSNPs) have been found in the SOCS2 gene, which could affect protein function. However, there is limited understanding of disease susceptibility and abnormal functioning associated with these mutated SOCS2 gene. …”
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Effects of dietary propyl gallate and Lactobacillus plantarum addition on growth, intestinal morphology, antioxidant capacity, and immune functions of Pekin ducks by L. Dai, B.W. Wang, W.L. Fan, W. Qian, J. Zhang, B.H. Wang, B.B. Zhang, M.A. Zhang

“…The interaction between probiotic bacteria and polyphenol antioxidants can potentially enhance animal health. The present study examined the effects of propyl gallate and Lactobacillus plantarum supplementation on the growth, intestinal morphology, antioxidant capacity, and immune functions of Pekin ducks. …”
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Prolonged sitting is not associated with altered shear‐mediated dilation of the internal carotid artery, despite impairing lower limb endothelial function by Shotaro Saito, Kento Dora, Marino Karaki, Narumi Kunimatsu, Hayato Tsukamoto, Jun Sugawara, Erika Iwamoto, Shigehiko Ogoh

“…Abstract The present study aims to examine the effect of 4 h of continuous sitting on cerebral endothelial function, which is a crucial component of cerebral blood flow regulation. …”
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Effects of a warm-up program on jump-landing pattern and lumbopelvic function in female basketball players with dynamic knee valgus by Mohadeseh Rostami, Parisa Sedaghati, Hassan Daneshmandi

“…The present study employed a quasi-experimental design. …”
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Agronomic improvement using gamma ray induced mutagenesis is associated with changes in phytochemical and phytohormonal profiles in functional rice variety ‘Gathuwan’ by Anjali Chauhan, Rahul Checker, Parmeshwar K. Sahu, Raviraj Singh Patel, Samrath Baghel, Deepak Sharma, Deepak Sharma, Bikram K. Das

“…These metabolic changes support the functional potential of the mutants and provide insights into the biological mechanisms underlying their traits. …”
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Assessing post-COVID-19 functional recovery in healthcare workers: Insights from the 6-minute walking test and DLCO analysis by Salma AlBahrani, Ali AlBarrak, Jaber S. Alqahtani, Nawal AlGubaisi, Hamoud Alkurdi, Dalia Alburaiki, Abdulrahaman AlGhamdi, Mohammed AlOthaiqy, Osama Faqihi, Meshael Musaed Almershad, Fatimah Hassan Hakami, Asmaa AlAbbadi, Mariam Hassan Hakami, Alaa AlMaimouni, Zechariah Jebakumar Arulanantham, Jaffar A. Al-Tawfiq

“…Introduction: The COVID-19 pandemic has impacted healthcare workers (HCWs) worldwide, necessitating an understanding of its effects on their health and functional capacity. This study utilized the 6-Minute Walk Test (6MWT) and pulmonary function test (PFT) to evaluate post-infection recovery of HCWs, and analyzed the results in relation to comorbidities, symptoms, and healthcare admission. …”
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Stimulation of regulatory dendritic cells suppresses cytotoxic T cell function and alleviates DEN-induced liver injury, fibrosis and hepatocellular carcinoma by Junjie Wang, Pixu Gong, Qingqing Liu, Menglei Wang, Dengfang Wu, Mengyu Li, Shujie Zheng, Han Wang, Han Wang, Qiaoming Long

“…BackgroundDendritic cells (DCs) are versatile professional antigen-presenting cells and play an instrumental role in the generation of antigen-specific T-cell responses. …”
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HAX1, gene responsible for Kostmann syndrome, regulates gingival epithelial barrier function via intracellular trafficking of JAM1 by Keita Tanigaki, Tsukasa Tamamori, Naoko Sasaki, Risako Matsumura, Shunsuke Yamaga, Akito Sakanaka, Atsuo Amano, Michiya Matsusaki, Hiroki Takeuchi, Masae Kuboniwa

“…In the present study, the effects of HAX1 on gingival barrier function were investigated.ResultsExaminations of immortalized human gingival epithelial (IHGE) cells showed HAX1 localization in mitochondria. …”
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Respiratory function and respiratory complications in spinal cord injury: protocol for a prospective, multicentre cohort study in high-income countries by David J Berlowitz, Maria T E Hopman, Martin Schubert, Gabi Mueller, Martin W G Brinkhof, Xavier Jordan, Anja M Raab, Karin Postma, David Gobets, Sven Hirschfeld, Burkhart Huber, Margret Hund-Georgiadis, Renate Wildburger

“…After a cervical or thoracic lesion, impairment of the respiratory muscles decreases respiratory function, which increases the risk of respiratory complications. …”
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