An Advanced Combinatorial System from <i>Vitis vinifera</i> Leaves and Propolis Enhances Antioxidants’ Skin Delivery and Fibroblasts Functionality by Sophia Athanasopoulou, Eleni Spanidi, Eleni Panagiotidou, Andrea Cavagnino, Anaïs Bobier, Konstantinos Gardikis

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Emerging role of the calcium-activated, small conductance, SK3 K+ channel in distal tubule function: regulation by TRPV4. by Jonathan Berrout, Mykola Mamenko, Oleg L Zaika, Lihe Chen, Wenzheng Zhang, Oleh Pochynyuk, Roger G O'Neil

“…It is concluded that SK3 is functionally expressed in the distal nephron and collecting ducts where induction of TRPV4-mediated Ca2+ influx, leading to elevated intracellular Ca2+ levels, activates this high Ca2+-affinity K+ channel. …”
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Identification of the Parameters of the Szpica–Warakomski Method’s Rectilinear Trend Complementary to the Gaussian Characteristic Area Method in the Functional Evaluation of Gas In... by Dariusz Szpica, Jacek Hunicz, Andrzej Borawski, Grzegorz Mieczkowski, Paweł Woś, Bragadeshwaran Ashok

“…Thus, the usefulness of using the Szpica–Warakomski rectilinear trend in the functional evaluation of gas injectors of different designs and under different operating conditions was demonstrated.…”
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Enhanced CO2 Capture Performance Using Methyl Diethanolamine-functionalized Silica Gels: Assessing CO2 Capture Capacity by Petpitcha Boonmatoon, Pacharapol Nokpho, Pornpote Piumsomboon, Benjapon Chalermsinsuwan

“…Therefore, technology for capturing CO2 has been developed. At present, a wide variety of technologies have been proposed to capture CO2. …”
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Characterization of a pathogenic gain-of-function mutation in the N-terminal domain of STAT1 which is reported to be associated with eosinophilic esophagitis by Kristin Annawald, Anke Gregus, Oliver Wirths, Thomas Meyer

“…Recently, a case report described a gain-of-function (GOF) mutation in the STAT1 (signal transducer and activator of transcription 1) protein (D65A) to be associated with this disease. …”
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The Impact of Open-Skill Exercises and E-Sports on Cognitive Function: A Narrative Review of Their Role in Preventing Cognitive Decline and Dementia by Shuzo Kumagai, Hyuntae Park, Si Chen, Takao Yamasaki

“…<b>Background/Objectives:</b> There is still no clear consensus regarding the efficacy of exercise interventions in maintaining or improving cognitive function among independent older adults, as well as individuals with mild cognitive impairment (MCI) or dementia. …”
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The Effect of the Functions of the Knowledge Management Maturity Triple Model on the Acquisition of Competitive Advantage Capabilities (Case Study: National Petrochemical Company) by Sayyed Mohammad Reza Davoodi, Mojgan Gharibi Marzankola, Mohammadreza Hamidizadeh, Valiullah Ali Mohammadi

“…Purpose: This study is conducted to investigate the effect of the functions of the knowledge management maturity triple model (Infosys model, general model, and KPMG model) on gaining competitive advantage capabilities in the National Petrochemical Company.Methodology: The present study contains 6 hypotheses (quantitative) and one question (qualitative). …”
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Narcissism between cold-blooded and hot-headed characters in toxic online behaviors. The moderating role of the R4 functional drivers by Oronzo Mazzeo, Giuseppe La Selva, Manuela Longo, Lucia Monacis

“…Moreover, there has been no clear distinction on which specific dimension (grandiose or vulnerable) is related to online aggressive behaviors. Therefore, the present study examined the relationships of the two variants of narcissism with cyberbullying and trolling behavior, taking into account the moderating role of four different functional drivers.MethodThree self-reported questionnaires were administered to 202 undergraduate students. …”
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Biological Activity and Structure–Activity Relationship of Functionalized Thiols Against <i>Leishmania major</i>, the Agent of Human Cutaneous Leishmaniasis by Taylor Henne, Linsey Curry, Kenlei Gunther, Cameron Smith, Hannah Braunstein, Abdikani Omar Farah, Timothy K. Beng, Blaise Dondji

“…Together, our data demonstrate that functionalized thiols have an in vivo anti-<i>Leishmania</i> activity that is directly linked to their chemical structure.…”
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Prioritization of candidate cancer drugs based on a drug functional similarity network constructed by integrating pathway activities and drug activities by Jieyi Di, Baotong Zheng, Qingfei Kong, Ying Jiang, Siyao Liu, Yang Yang, Xudong Han, Yuqi Sheng, Yunpeng Zhang, Liang Cheng, Junwei Han

“…Due to the speed, efficiency, relative risk, and lower costs compared to traditional drug discovery, the prioritization of candidate drugs for repurposing against cancers of interest has attracted the attention of experts in recent years. Herein, we present a powerful computational approach, termed prioritization of candidate drugs (PriorCD), for the prioritization of candidate cancer drugs based on a global network propagation algorithm and a drug–drug functional similarity network constructed by integrating pathway activity profiles and drug activity profiles. …”
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Screening of Chinese giant salamander meat hydrolysates with DPP-Ⅳ inhibitory activity and systematic elucidation of their hypoglycemic functions in mouse model by Shucheng Li, Changge Guan, Yi Wang, Haihong Chen, Wei Li, Songjun Wang, Chong Zhang, Xinhui Xing

“…Type 2 diabetes (T2D) presents a significant health challenge, underscoring the need for functional foods and nutraceutical hypoglycemic bioactive peptides for its prevention. …”
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A novel fibrinogen-related protein with two coiled-coil regions from Chlamys farreri functions as immune recognition molecule by Meijia Li, Leilei Wang, Lingling Wang, Weilin Wang, Chuanyan Yang, Linsheng Song

“…These findings collectively suggested that CfFREP functioned as a canonical immune recognition molecule in scallop, which offers fresh perspectives on the functions of mollusk FREPs.…”
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Functional movement screen test as an predictor for jumping tests performance and on-ice skating sprint in elite level ice hockey players. by Jakub Baron, Maciej Hołub, Arkadiusz Stanula

“…The main purpose of this research was to establish selected motor skills measured in off-ice and on-ice conditions in ice hockey players using the functional movement screen test, vertical jumps, and on-ice sprints. …”
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Are Functional Performance Test Scores Better When Compared to Baseline or Contralateral Limb Scores Following LE Injury in Adolescent Athletes? by Edward Jones, Jessica Jochum, Hannah Corn, Michaela O'Brien, Melissa Parks, Jamal Armoush, Amanda Annee

“…# Background Functional performance tests (FPT) have been used with athletes following an injury to determine readiness to return-to-play (RTP), usually using limb symmetry indices to the contralateral limb or a baseline score. …”
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Natural SEL1L variants rescue a model of NGLY1 deficiency and modify ERAD function and proteasome sensitivity. by Travis K Tu'ifua, Clement Y Chow

“…We found that the SEL1LS780P and SEL1LΔ806-809 variants improve resistance to ER stress, with enhanced ERAD function as a likely contributing mechanism. This effect depends on NGLY1 activity, further implicating NGLY1 in general ERAD function. …”
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Quality of life and objective functional impairment in lumbar spinal stenosis: a protocol for a systematic review and meta-analysis of moderators by Andrea Pozza, Fabio Ferretti, Anna Coluccia, Roberto Gusinu, Giacomo Gualtieri, Vitaliano Francesco Muzii

“…There is no comprehensive review on quality of life and objective functional impairment in LSS. This paper presents the protocol of the first systematic review and meta-analysis summarising evidence about quality of life and functional impairment in patients with LSS compared with healthy controls. …”
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How achievement of a stroke care pathway is associated with functional outcome after stroke: a national, register-based study by Elin Bergh, Torunn Askim, Ole Morten Rønning, Stian Lydersen, Hild Fjaertoft, Bente Thommessen

“…Abstract Background Care pathways are introduced to ensure adherence to treatment guidelines for several patient groups. In the present study, we aimed to evaluate whether the achievement of key objectives within the recently implemented Norwegian stroke care pathway (SCP) was associated with functional outcome 3 months after stroke and to identify the characteristics of patients who achieved the recommended goals. …”
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Towards universal health coverage in the WHO African Region: assessing health system functionality, incorporating lessons from COVID-19 by Juliet Nabyonga-Orem, Regina Titi-Ofei, Felicitas Zawaira, Prosper Tumusiime, Gerard Schmets, Aminata Binetou-Wahebine Seydi

“…We present an approach to provide countries with information on the functionality of their systems in a manner that will facilitate movement towards universal health coverage. …”
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Formulation and phytochemical analysis of a potentially functional beverage from combining a leaf extract and pulp of Annona muricata (Annonaceae) by Yolanda Nolasco-González, María de Lourdes García-Magaña, Andrés Eloy León-Fernández, Juan L. Monribot-Villanueva, José A. Guerrero-Analco, Efigenia Montalvo González

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Cognitive impairment in chronic heart failure. How new therapeutic options for the treatment of chronic heart failure affect cognitive function? by Y. O. Aksenova, Y. F. Osmolovskaya, A. A. Petrukhina, I. V. Zhirov, A. G. Beniashvili, S. N. Tereshchenko, M. A. Morozova

“…For example, implantation of an artificial left ventricle may improve cognitive function; however, there are studies on immediate improvement in cognitive function followed by gradual deterioration over time after implantation of an artificial left ventricle, which requires long-term study In addition, evidence is provided for the effectiveness of using a relaxation scenario in virtual reality technology to reduce anxiety and affective complaints in somatic hospitalized patients, but the ability to improve cognitive function in patients with chronic heart failure remains to be explored.…”
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