WHSC1/NSD2 regulates immune infiltration in prostate cancer by Kunle Odunsi, Junko Matsuzaki, Takemasa Tsuji, Sebastiano Battaglia, Richard C. Koya, Prashant K Singh, Muzamil Y Want, James L Thorne, Ellen Karasik, Bryan Gillard, Eduardo Cortes Gomez, Amit Lugade

“…We validated those results in vitro, demonstrating that genetic and pharmacological inhibition of WHSC1 restores antigen presentation. This occurs via an elegant epigenetic regulation of gene expression at the chromatin and DNA methylation levels. …”
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AI-driven pharmacovigilance: Enhancing adverse drug reaction detection with deep learning and NLP by Dr. Bharti Khemani, Dr. Sachin Malave, Samyukta Shinde, Mandvi Shukla, Razzaq Shikalgar, Harshita Talwar

“…In the healthcare industry, the ever-increasing volume of clinical trial data presents challenges for ensuring drug safety and detecting adverse drug reactions (ADRs). …”
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Fast Alkaline Hydrothermal Synthesis of Pyrophosphate BaCr₂(P₂O₇)₂ Nanoparticles and Their NIR Spectral Reflectance by Diego Emiliano Carrillo-Ramírez, Juan Carlos Rendón-Angeles, Zully Matamoros-Veloza, Jorge López-Cuevas, Isaías Juárez-Ramírez, Tadaharu Ueda

“…Recently, the development of nanoparticle pigments has attracted interest in chemical preparation due to their potential functional properties, such as phosphate-based pigments. …”
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Knee-Sparing Resection and Reconstruction Surgery for Bone Sarcoma Using 3D-Surgical Approach: Average of 5-Year Follow-Up by Amit Benady, Noy Yehiel, Ortal Segal, Omri Merose, Amir Sterenheim, Osnat Sher, Ben Efrima, Eran Golden, Yair Gortzak, Solomon Dadia

“…This study aims to evaluate the effectiveness of a precise 3D-based surgical approach for knee-sparing tumor resections, assessing its feasibility and its impact on surgical, oncological, and functional outcomes. <i>Materials and Methods</i>: This single-center retrospective study presents the surgical and oncological outcomes of knee-sparing surgeries following bone sarcoma resections. …”
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Prevalence and determinants of pulmonary hypertension in rheumatic heart disease patients at university of Gondar comprehensive specialized hospital: a retrospective study from 201... by Fikadu Alemiye Molla, Desalew Getahun Ayalew, Hailemaryam Alemu Astatk, Abebe worku Teshager, Gebrehiwot Lema Legesse, Daniel Belay Agonafir, Shibabaw Fentahun, Belete Sisay Assefa, Tilahun Nega Godada, Deresse Abebe Gebrehana, Abilo Tadesse

“…Abstract Introduction Most Rheumatic heart disease patients present with advanced disease and complications, pulmonary hypertension being one of the main complications. …”
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Addressing Shortcomings in Contingency Standards of Care by Alexander Quan

“…This is a concern because it is unclear whether contingency measures can meet their goal of achieving functionally equivalent patient outcomes when resource allocation must be balanced with patient-centered care.[18] The care under contingency standards is meant to be functionally equivalent to regular care. …”
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Spectrum of Cortactin Isoforms in the Urine of Patients with Liver Cirrhosis and Their Diagnostic Value as a Potential Molecular Marker of its Severity by Fayura O., Starikovych M., Abrahamovych O., Abrahamovych M., Stoyka R., Kit Yu.

“…Since the protein content of human urine is closely related to the peculiarity of the functioning of biological systems, its qualitative and quantitative characteristics are promising markers for control of various processes in organism. …”
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Special Issue on Contemporary Research Studies in Operations Research, Business Analytics, and Business Intelligence by Viswanath Kumar Ganesan, S. Vinodh, Malolan Sundararaman, M. Vimala Rani, M. Mathirajan

“…Optimization Algorithms: Developing efficient algorithms to solve linear fractional transshipment problem with multi-objective linear fractional functions. 4. AI in Business Intelligence: Investigating long-term impacts of AI-enabled Business Intelligence tools on data-driven decision-making and organizational performance. 5. …”
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Identifying the Dimensions and Components of Virtual Arabic Language Education in Iraq by Abbas Taher Allavi Gharabat, Nasrolah Ghashghaeizadeh, Jalal Shanta Jabir, Faranak mosavi

“…Theoretical Framework Virtual Education The term virtual education includes a wide range of applications and functions, including non-face-to-face education and electronic libraries (Abbasi Kasani, 2020). …”
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Validation of a Set of Clinical Criteria for the Diagnosis of Secondary Progressive Multiple Sclerosis by Alin Ciubotaru, Daniel Alexa, Cristina Grosu, Lilia Böckels, Ioana Păvăleanu, Alexandra Maștaleru, Maria Magdalena Leon, Roxana Covali, Emanuel Matei Roman, Cătălina Elena Bistriceanu, Cristina Mihaela Ghiciuc, Doina Azoicăi, Emilian Bogdan Ignat

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The prevalence and correlates of low resilience in patients prior to discharge from acute psychiatric units in Alberta, Canada by Ernest Owusu, Wanying Mao, Reham Shalaby, Hossam Eldin Elgendy, Belinda Agyapong, Ejemai Eboreime, Mobolaji A. lawal, Nnamdi Nkire, Yifeng Wei, Peter H. Silverstone, Pierre Chue, Xin-Min Li, Wesley Vuong, Arto Ohinmaa, Valerie Taylor, Carla T. Hilario, Andrew J. Greenshaw, Vincent I. O. Agyapong

“…Although such traumatic events can precipitate psychiatric disorders, many individuals exhibit high resilience by adapting to such events with little disruption or may recover their baseline level of functioning after a transient symptomatic period. Low levels of resilience are under-explored, and this study investigates the prevalence and correlates of low resilience in patients before discharge from psychiatric acute care facilities. …”
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Impact of the COVID-19 Pandemic and the 2021 National Institute for Health and Care Excellence Guidelines on Public Perspectives Toward Myalgic Encephalomyelitis/Chronic Fatigue Sy... by Iliya Khakban, Shagun Jain, Joseph Gallab, Blossom Dharmaraj, Fangwen Zhou, Cynthia Lokker, Wael Abdelkader, Dena Zeraatkar, Jason W Busse

“… BackgroundMyalgic encephalomyelitis (ME), also referred to as chronic fatigue syndrome (CFS), is a complex illness that typically presents with disabling fatigue and cognitive and functional impairment. …”
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Gender-specific effects of genetic variants within Th1 and Th17 cell-mediated immune response genes on the risk of developing rheumatoid arthritis. by Rafael Cáliz, Luz María Canet, Carmen Belén Lupiañez, Helena Canhão, Helena Canhão, Alejandro Escudero, Ileana Filipescu, Juana Segura-Catena, María José Soto-Pino, Manuela Expósito-Ruiz, Miguel Ángel Ferrer, Antonio García, Lurdes Romani, Alfonso González-Utrilla, Teresa Vallejo, Eva Pérez-Pampin, Kari Hemminki, Asta Försti, Eduardo Collantes, João Eurico Fonseca, Juan Sainz

“…In phase one, 27 functional/tagging polymorphisms in C-type lectins and MCP-1/CCR2 axis were genotyped in 458 RA patients and 512 controls. …”
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Biological role and use of L-glutamic acid and its influence on the body by O. O. Korytko

“…L-glutamic acid (GA) is an non-essential ubiquitous amino acid present in most foods in either the free form (as free glutamate, Glu) or bound to peptides and proteins. …”
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Encuesta Nacional de Tendencias de Fitness en España para 2018 (National Survey of Fitness Trends in Spain for 2018) by Oscar L. Veiga, Manel Valcarce Torrente, Adrian King Clavero, Miguel Angel de la Camara Serrano

“…The more relevant trends in the Spanish context are "educated, certified and experienced fitness professionals", "functional training", "exercise and weight loss", "high intensity intervallic training", "personal training" and “body weight training”. …”
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Depalmitoylase ABHD16A negatively regulates the anti-hepatitis B virus activity of IFITM1 by Xin Wen, Mingyang Liu, Yali Fan, Junfei Xu, Zhaoyan Wang, Lin Mao, Weizhen Gu, Xuemeng Shi, Jun Xu

“…However, the mechanisms of IFITM regulation on hepatitis B virus (HBV), which induces chronic infection resulting in cirrhosis as well as liver cancer, remain poorly characterized. In the present study, we identified that HBV infection significantly increased the expression of IFITM1. …”
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Tracing Sentinel Lymph Nodes and Inhibiting Lymphatic Metastasis with TiN Nanobipyramids Through Photothermal Therapy by Xu YN, Bai X, Chen JL, Wu X, Yin D, Yuan G, Dai R, Zhu XM, Wang J

“…The effect of TiN NBP-based photothermal ablation of SLNs combined with removal of primary tumors on pulmonary metastasis was studied.Results: The TiN NBPs with dual bright- and dark-field imaging functions show high drainage in lymph nodes and thus can act as a potential substitute for SLN tracing. …”
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Integrating multi-omics data to optimize immunotherapy in endometrial cancer: a comprehensive study by Xin Guan, Rongchuan Cao, Longbi Liu, Lin Ma, Ning Gao, Yanfei Yang, Mingyue Xiao, Rui Du, Yuzhe Su, Zhen Wang, Xiaofeng Liu, Lu Han

“…The study employed functional enrichment and gene set variant analysis to discern noteworthy disparities in biological pathways across various groups. …”
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Optimalisasi Badan Penasihatan Pembinaan dan Pelestarian Perkawinan Kepenghuluan Dalam Meminimalisir Angka Perceraian by Bagus Kusumo Hadi, Opia Tatarisanto, Adam Dewantara Putra, Asyifa Nur Azizah, Taufik Pajar Pebriansyah

“…The purpose of this writing is to explain the factors that contribute to the ineffectiveness of the leadership of the Marriage Advisory, Development and Preservation Agency or commonly called BP4, by proposing or presenting immediate solutions to disputing married couples. …”
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Análisis espacial de datos para clasificar Musáceas en zonas Bananeras no tradicionales del Ecuador by Patricia Gómez, Omar Ruíz Barzola, Hernán Garcés, Esther Lilia Peralta García

“…Como un aporte de la estadística en este tema se realiza el presente proyecto cuyo objetivo es identificar mediante descriptores fisiológicos de las plantas (altura del pseudotallo, área de la hoja, ancho de márgenes del peciolo, longitud del peciolo, proporción de la hoja) en aquellos sectores donde existen plantas que tengan características que puedan resultar fáciles de aprovechar. …”
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