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Suggested Topics within your search.
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38721
Construction of a novel five programmed cell death-related gene signature as a promising prognostic model for triple negative breast cancer
Published 2025-04-01“…Gene set enrichment analysis was carried out to investigate the pathways and molecular functions. Results Five PCD-related genes including SEPTIN3, SCARB1, CHML, SYNM, and COL5A3 were identified to establish the PCD-related risk score for TNBC patients. …”
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38722
Cardiac-targeted FGF4 encapsulated nanoliposomes improve acute myocardial injury induced by ischemia-reperfusion and adriamycin in in vitro and in vivo models
Published 2025-08-01“…In the cellular model, we analyzed the molecular mechanism by which FGF4 exhibits its biological functions. We found that FGF4 released from FGF4-NANO-IMTP binds to its FGFR1, which in turn activates the AMPK signaling pathway. …”
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38723
Drosophila melanogaster as a model system for studying the effects of porcine rotavirus on intestinal immunity
Published 2025-07-01“…Given that flies primarily consume decaying organic matter, harmful microorganisms present in their food can enter the intestine, leading to frequent infections by exogenous pathogens. …”
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38724
Gene selection based on adaptive neighborhood-preserving multi-objective particle swarm optimization
Published 2025-05-01“…The analysis of high-dimensional microarray gene expression data presents critical challenges, including excessive dimensionality, increased computational burden, and sensitivity to random initialization. …”
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38725
Oral health-related quality of life in patients with type II diabetes mellitus: a systematic review and meta-analysis
Published 2025-04-01“…We searched trials both with or without comparisons to healthy controls and presenting OHIP-14 results as a severity of impact, namely, the mean OHIP-14 total score. …”
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38726
Formulation and Evaluation of Licorice-Extract-Enhanced Chitosan, PVA, and Gelatin-Derived Hydrogels for Wound Dressing
Published 2025-04-01“…FTIR analysis confirmed the presence of specific functional groups within the molecules. XRD exhibited the amorphous nature of hydrogels. …”
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38727
Integration of Microarray Data and Single-Cell Sequencing Analysis to Explore Key Genes Associated with Macrophage Infiltration in Heart Failure
Published 2024-12-01“…Cellular communication revealed that macrophages form a network of interactions with neutrophils to support each other’s functions and maintenance. The complex efferent and afferent signals are closely associated with myocardial fibrosis.Conclusion: SERPINA3, GPAT3, ANPEP, and FCER1G can potentially serve as immune therapeutic targets and central biomarkers. …”
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38728
Análisis proteómico de la estructura del esmalte dental humano para la determinación del sexo en investigaciones forenses. Revisión narrativa Proteomic analysis of human tooth ena...
Published 2024-09-01“…Dental attrition is a functional condition caused by max- illary and mandibular teeth contact during occlusion move- ments, causing the gradual loss of enamel and dentin in a proportion that increases depending on the time elapsed. …”
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38729
Potential regulatory role of microRNAs in the development of bovine gastrointestinal tract during early life.
Published 2014-01-01“…The expression levels of miR-15/16, miR-29 and miR-196 were positively correlated with the copy numbers of 16S rRNA gene of Bifidobacterium or Lactobacillus species or both (P<0.05). Functional analysis using Ingenuity Pathway Analysis identified the above mentioned differentially expressed miRNAs as potential regulators of gut tissue cell proliferation and differentiation. …”
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38730
Glycodelin is a potential biomarker for malignant tumors
Published 2023-01-01“…Further studies of the functional properties of glycodelin are needed to develop promising strategies in cancer therapy.…”
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38731
Acoustic voice assessment in Parkinson's disease patients submitted to posteroventral pallidotomy Parametros acústicos da voz em pacientes com doença de Parkinson submetidos a pali...
Published 2005-03-01“…CONCLUSION: This study shows that pallidotomy has little improvement on functional use of communication of PD patients.<br>O uso prolongado da levodopa na doença de Parkinson (DP) pode ocasionar alterações em seu rendimento e possibilitou o interesse no ressurgimento da palidotomia. …”
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38732
A ketogenic diet alleviates the apoptosis of granulosa cells by inhibiting the activation of cGAS-STING signaling pathway in PCOS mice
Published 2024-11-01“…Results Our data showed that KD treatment significantly increased blood ketone levels and reduced body weight. Ovarian functions were improved in some letrozole + KD mice. …”
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38733
Twenty-year changes in the clinical and echocardiographic characteristics of patients with early postinfarction remodeling after primary ST-segment elevation myocardial infarction
Published 2023-01-01“…To compare structural and functional left ventricular (LV) changes in the early period of myocardial infarction (MI) within 20 years on the basis of the Emergency Cardiology Department of the Cardiology Research Institute (Tomsk).Material and methods. …”
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38734
Design and efficiency improvement of eco-conscious Sr3PBr3 and Sr3NCl3 double perovskite solar cells with IGZO and Cu2O as ETL and HTL
Published 2025-06-01“…Additionally, the research explores the influence of various factors such as temperature, interface defects, rates of carrier production and recombination, and the work functions of return contact materials on performance. …”
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38735
Information and measuring system for geometric and motion parameters determination of industrial products by their video images
Published 2025-07-01“…The article presents the information and measuring system for geometric and motion parameters determination of industrial products, for example, at a stone processing or machine-building enterprise. …”
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38736
Brake rigging dynamic simulation under braking on a track section with irregularities (the case of a passenger car)
Published 2020-03-01“…A full-scale computer model of a passenger car, which includes the designed contact module “linkage brake pad - wheel working surface”, has been developed in the “Universal Mechanism” software package. The car is present-ed as a system of solids connected by elastic and dissipative elements. …”
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38737
Modeling of concrete-filled PVC tube columns confined with CFRP strips under uniaxial eccentric compression: machine learning and finite element approaches
Published 2025-02-01“…Analytical models were developed to express the confined concrete strength and strain as functions of the constituent properties and dimensionless confinement parameters. …”
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38738
The influence of halogen-containing modifier on the thermo-oxidative stability of styrene–butadiene–styrene triblock copolymers
Published 2025-03-01“…However, the creation of new functional materials based on modified styrene–butadiene block copolymers will enable the development of materials with enhanced resistance to thermal-oxidative degradation. …”
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38739
Evaluation of Wuchereria bancrofti GST as a vaccine candidate for lymphatic filariasis.
Published 2009-06-01“…<h4>Methods/principal findings</h4>In the present study, the GST gene was cloned from the third stage larval (L3) cDNA libraries of Wuchereria bancrofti, and recombinant GST (WbGST) was expressed and purified. …”
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38740
Mobilome of Environmental Isolates of <i>Clostridioides difficile</i>
Published 2025-07-01“…Conclusions: The results of the current study suggest that the identified plasmids are abundant and may encode functions that are relevant to <i>C. difficile</i> physiology. …”
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