Protein tyrosine phosphatase receptor type kappa (PTPRK) revisited: evolving insights into structure, function, and pathology by Chen Zheng, Ting Liu, An Qi Wang, Xing An Chen, Rong Zhe Zhang, Xuan Chao Wang, Chao Yue Lv, Ru Lu Pan, Ou Chen Wang, Xin-Cheng Lu

“…In this review, we elucidate the structural characteristics and functional roles of PTPRK in cellular signaling and disease pathogenesis. …”
Get full text

Characterization of the heat shock factor RcHsfA6 in Rosa chinensis and function in the thermotolerance of Arabidopsis by Yanhui Kang, Yuan Yang, Pei Sun, Maofu Li, Hua Wang, Xiangyi Sun, Wanmei Jin

Get full text

The songbird connectome (OSCINE-NET.ORG): structure–function organization beyond the canonical vocal control network by Andrew Savoy, Katherine L. Anderson, Joseph V. Gogola

“…This comprehensive digital map includes all known connectivity data, covering major brain superstructures and functional networks. Our analysis reveals that the songbird brain exhibits small-world properties, with highly connected communities functionally designated as motor, visual, associative, vocal, social, and auditory. …”
Get full text

Silent changes in taxonomic, functional and phylogenetic diversity of birds in Qiyunshan National Nature Reserve, south China by Binqiang Li, Jian Lu, Xin Zhong, Daohan Li, Bailin Li, Nehafta Bibi, Kechuan Linghu, Shanjun Ma, Pinghua Zhong

“…Protected areas have the potential to attract new bird species with similar functional and genetic relationships to those already present. …”
Get full text

Metagenomic and physicochemical profiling reveal microbial functions in pit mud for Jiang-Nong Jianxiang Baijiu fermentation by Lianbin Cao, Hongmei Sun, Ziyi Xu, Xiaoxiao Xu, Guangchuan Shi, Jianqiang Zhang, Changli Liang, Tongbiao Li, Chaoying Liu, Mingcheng Wang, Shilin Tian, Enzhong Li

Get full text

The Effectiveness of Acceptance and Commitment-Based Therapy on the Immune Function and Activity Limitations in Patients With Irritable Bowel Syndrome by Sepideh Shakernejad, Javad Khalatbari, Majid-Mahmoud Alilou

“…According to the results, activity limitations (P=0.027) and safety performance (P=0.034) were significantly different before and after the intervention. Conclusion: The present study’s findings show that acceptance and commitment-based therapy can play an influential role in improving patients’ immune function and promoting their activity limitations. …”
Get full text

Assessing subaortic right ventricle function after atrial switch repair through myocardial work analysis by Ana Moya, Sofie Verstreken, Dimitri Buytaert, Monika Beles, Elayne Kelen de Oliveira, Marc Vanderheyden, Alexander Van De Bruaene, Werner Budts

“…While prolonged QRS has been associated with worse prognosis in these patients, current echocardiographic tools fall short in adequately assessing the (mal)performance and function decline of the sRV during follow-up. The present study is the first to characterize Myocardial Work (MW) indices of the sRV in D-TGA patients after Mustard/Senning repair. …”
Get full text

Maternal Abnormal Liver Function in Early Pregnancy and Spontaneous Pregnancy Loss: A Retrospective Cohort Study by Huibin Yang, Tianyi Tang, Qianlei Qian, Xiaohua Zhang, Yinan Liu, Xiaoyan Zhou, Yanling Zhang, Longmei Jin, Xiaotian Chen

“…Here, we investigated whether maternal abnormal liver function in early pregnancy contributed to the incidence of SPL. …”
Get full text

Cardiac function in children with congenital diaphragmatic hernia: cardiac strain at birth and at 2–5 weeks of age by Katarina Övermo Tydén, Katarina Övermo Tydén, Kerstin Magnusson, Carmen Mesas Burgos, Carmen Mesas Burgos, Carmen Mesas Burgos, Baldvin Jonsson, Felicia Nordenstam, Felicia Nordenstam

“…IntroductionNeonates with congenital diaphragmatic hernia (CDH) often present with pulmonary hypertension and various forms of cardiac dysfunction, affecting right or left ventricle or both. …”
Get full text

Interferon-γ Signaling in Eosinophilic Esophagitis Affects Epithelial Barrier Function and Programmed Cell DeathSummary by Megha Lal, Caitlin M. Burk, Ravi Gautam, Zoe Mrozek, Karina E. Canziani, Tina Trachsel, Jarad Beers, Margaret C. Carroll, Duncan M. Morgan, Amanda B. Muir, Wayne G. Shreffler, Melanie A. Ruffner

“…The functional impact of IFN-α and IFN-γ on epithelial cells was investigated using organoid models. …”
Get full text

IgG detection in human serum employing non-functionalized chromium doped zinc gallate nanoparticles by Zied Ferjaoui, Capucine Zimmer, Celina Matuszewska, Corinne Chanéac, Bruno Viana, Cédric Bouzigues, Daniel Scherman, Nathalie Mignet, Cyrille Richard

“…This study highlights the promising potential for biosensing applications of persistent ZGO nanophosphors for IgG detection in a complex medium (undiluted human serum), with a linear range from 1 ng mL−1 to 104 ng mL−1 and a limit of detection of 0.01 ng mL−1. The present optimization of ZGO nanophosphor synthesis offers promising prospects for medical diagnostics due to their increased sensitivity and ability to eliminate autofluorescence interference, as well as their ease of use, since no functionalization of the ZGO NPs is required before use.…”
Get full text

Machine learning predicts improvement of functional outcomes in spinal cord injury patients after inpatient rehabilitation by Mohammad Rasoolinejad, Irene Say, Peter B. Wu, Xinran Liu, Yan Zhou, Yan Zhou, Nathan Zhang, Emily R. Rosario, Daniel C. Lu, Daniel C. Lu, Daniel C. Lu

“…IntroductionSpinal cord injury (SCI) presents a significant burden to patients, families, and the healthcare system. …”
Get full text

Investigating the potential immunomodulatory effects of commercial oral probiotic supplements on equine gastrointestinal tract barrier function by Agnieszka Żak-Bochenek, Paulina Żebrowska-Różańska, Joanna Bajzert, Łukasz Łaczmański, Bogumiła Szponar, Natalia Siwińska, Klaudia Gładysz, Katarzyna Sikorska, Anna Chełmońska-Soyta

Get full text

THE OUTCOMES OF FUNCTIONING OF UNIFIED SYSTEM OF INDIVIDUAL DOSE CONTROL OF RUSSIAN FEDERATION CITIZENS BASED ON 2014 DATA by V. S. Repin, N. K. Baryshkov, A. A. Bratilova, K. V. Varfolomeeva, Ju. N. Goncharova, D. V. Kononenko, T. A. Kormanovskaja, S. I. Kuvshinnikov, L. V. Repin, I. K. Romanovich, A. V. Svetovidov, I. P. Stamat, O. E. Tutel’jan

Get full text

Vaccination generates functional progenitor tumor-specific CD8 T cells and long-term tumor control by Mary Philip, Mary K Washington, Joseph T Roland, Carlos R Detrés Román, Megan M Erwin, Michael W Rudloff, Frank Revetta, Kristen A Murray, Natalie R Favret, Jessica J Roetman

“…We assessed the immunophenotype (CD44, PD1, TCF1, and TOX expression) and function (TNFα and IFNγ cytokine production) of tumor/TAG-specific CD8 T cells in mice with early and late liver lesions by flow cytometry. …”
Get full text

Effects of Newer Antidiabetic Drugs on Endothelial Function and Arterial Stiffness: A Systematic Review and Meta-Analysis by Konstantinos Batzias, Alexios S. Antonopoulos, Evangelos Oikonomou, Gerasimos Siasos, Evanthia Bletsa, Panagiota K. Stampouloglou, Chara-Vasiliki Mistakidi, Marina Noutsou, Niki Katsiki, Periklis Karopoulos, Georgios Charalambous, Anastasia Thanopoulou, Nicholas Tentolouris, Dimitris Tousoulis

“…We sought to explore their impact on vascular function. Methods. Published literature was systematically searched up to January 2018 for clinical studies assessing the effects of DPP-4 inhibitors, GLP-1 RAs, and SGLT-2 inhibitors on endothelial function and arterial stiffness, assessed by flow-mediated dilation (FMD) of the brachial artery and pulse wave velocity (PWV), respectively. …”
Get full text

EIGER. VI. The Correlation Function, Host Halo Mass, and Duty Cycle of Luminous Quasars at z ≳ 6 by Anna-Christina Eilers, Ruari Mackenzie, Elia Pizzati, Jorryt Matthee, Joseph F. Hennawi, Haowen Zhang, Rongmon Bordoloi, Daichi Kashino, Simon J. Lilly, Rohan P. Naidu, Robert A. Simcoe, Minghao Yue, Carlos S. Frenk, John C. Helly, Matthieu Schaller, Joop Schaye

“…By measuring the two-point cross-correlation function of quasars and their surrounding galaxies, as well as the galaxy autocorrelation function, we infer a correlation length of quasars at 〈 z 〉 = 6.25 of ${r}_{0}^{\mathrm{QQ}}={22.0}_{-2.9}^{+3.0}\,\mathrm{cMpc}\,{h}^{-1}$ , while we obtain a correlation length of the [O iii ]-emitting galaxies of ${r}_{0}^{\mathrm{GG}}=4.1\,\pm 0.3\,\mathrm{cMpc}\,{h}^{-1}$ . …”
Get full text

Association of serum copeptin levels with pulmonary complications and heart right ventricular functions in common variable immunodeficiency by Mehmet Kılınç, Fatih Çölkesen, Filiz Sadi Aykan, Recep Evcen, Eray Yıldız, Bahadır Feyzioğlu, Metin Doğan, Yakup Alsancak, Sefa Tatar, Şevket Arslan

“…This study investigated the association between serum copeptin levels and right ventricular functions (RVF) and pulmonary complications in patients diagnosed with CVID. …”
Get full text

Functional Outcome of Epidural Steroid Injection in the Treatment of Chronic Low Backache due to Intervertebral Disc Prolapse by R Sahaya Jose, SL Binesh, N Kattu Bava, M Syed Moosa

“…Aims and objectives: The aim of the present study was to determine the functional outcome of ESI in treatment of chronic low backache due to intervertebral disc prolapse (IVDP) using Oswestry Disability Index (ODI) and numeric pain rating scale (NPRS) scoring system at baseline, 1 month, 3 months, 6 months, and 1 year. …”
Get full text

Functioning in patients with major depression treated with duloxetine or a selective serotonin reuptake inhibitor in East Asia by Novick D, Montgomery W, Haro JM, Moneta MV, Zhu G, Yue L, Hong J, Duenas H, Brugnoli R

“…Functioning was measured using the Sheehan Disability Scale (SDS). …”
Get full text