Design, Docking Analysis, and Structure–Activity Relationship of Ferrocene-Modified Tyrosine Kinase Inhibitors: Insights into BCR-ABL Interactions by Irena Philipova, Mariyana Atanasova, Rositsa Mihaylova, Asine Dailova-Barzeva, Stefan M. Ivanov, Rumyana L. Simeonova, Georgi Stavrakov

“…Ferrocene (Fc), a redox-active organometallic scaffold, has attracted significant attention in medicinal chemistry due to its favorable physicochemical and pharmacological properties. The present study explores the therapeutic potential of novel Fc-functionalized analogues of imatinib and nilotinib, aimed at targeting BCR-ABL1+ chronic myeloid leukemia (CML) cells. …”
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Initial shoot regeneration in the selenium hyperaccumulator Neptunia amplexicaulis and in vitro test system for selenium tolerance and accumulation by Bennet Buhmann, Jeroen van der Woude, Traud Winkelmann, Antony van der Ent

“…Research in the genetic background of the selenium accumulation and tolerance mechanisms of this species lacks biotechnological and molecular tools for functional genetics. Therefore, this study aimed to develop a de novo shoot regeneration protocol for N. amplexicaulis and validate an selenium accumulation test system. …”
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Hybrid Deep Neural Network Optimization with Particle Swarm and Grey Wolf Algorithms for Sunburst Attack Detection by Mohammad Almseidin, Amjad Gawanmeh, Maen Alzubi, Jamil Al-Sawwa, Ashraf S. Mashaleh, Mouhammd Alkasassbeh

“…The strength of DNNs is derived from their ability to model complex functions and to improve detection engines through deeper architecture. …”
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Optimization-Based Downscaling of Satellite-Derived Isotropic Broadband Albedo to High Resolution by Niko Lukač, Domen Mongus, Marko Bizjak

“…Afterwards, the remaining segments are grouped using K-means clustering, by considering orthophoto-visible (VIS) and near-infrared (NIR) bands. These segments present surfaces with similar materials and underlying reflectance properties. …”
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Pharmacoepidemiological analysis of therapy for chronic heart failure by D. D. Monakhova, V. A. Shchegoleva, T. I. Spiridonova

“…Men and women, aged from 50 to 80 years, with functional class (FC) II to IV, with reduced left ventricular ejection fraction (< 40 %) and with such diseases in anamnesis as arterial hypertension, coronary heart disease, atherosclerosis, diabetes mellitus were in the inclusion group. …”
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Prospects for the use of mobile applications for digitalization of the main business processes in the restaurant business by V.О., A.V.

“…Among the advantages of using mobile applications for the restaurant business, the authors single out the ability to order food or book tables online, implement a loyalty program (offer bonuses or vouchers), present guests with an up-to-date menu, quickly receive feedback from guests, etc. …”
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External Validation of a Prognostic Model for the Presence of Acute Appendicitis in Children by Olga N. Paize, Evgeniy A. Toneev, Aliia N. Mukhutdinova, Antonina V. Smolkina, Roman F. Shagdaleev, Eric A. Keshyan, Dmitry R. Shaidullin

“…Methods and Results: A new cohort of 101 pediatric patients with a confirmed diagnosis of acute appendicitis and 100 patients with functional gastrointestinal disorders were studied to assess the effectiveness of the developed logistic regression-based nomogram for predicting acute appendicitis in children. …”
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Extraction and characterization of humic acid from low-rank coal mined reserves in South Sumatra and its application on red chili (Capsicum annuum L.) in fertilizer exhausted soil by Mega Kartika Hermawan, Emma Trinurani Sofyan, Rija Sudirja, Anne Nurbaity

“…Laboratory-scale characterization revealed that locally sourced HA shares many functional groups with commercial leonardite-based HA. …”
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A bibliometric and visual analysis of Jak1 to explore trends and frontiers by Cong Yu, Jiamin Cao, Xiaodong Xie, Wenguang Chen, Ensi Hong, Ensi Hong

“…CiteSpace is used to analyze references and keywords of authors, institutions, countries, and commonly cited, and applies co-current and clustering functions to generate visual knowledge maps.ResultsA total of 3,686 articles were incorporated. …”
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Prediction of bronchopulmonary dysplasia course in children by analyzing clinico-biochemical indicators by L. M. Chernenko

“…At the present stage, one of the most important issues of pediatric pulmonology is to find ways of preventing the progression of chronic lung diseases. …”
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Postoperative Outcomes of Modified Carnoy’s Solution versus 5-Fluorouracil for Chemical Cauterisation following Enucleation and Peripheral Ostectomy in Patients with Odontogenic Ke... by Nidhi Vijay Kumar Bodiwala, Nitin Bhola

“…While MCS is a commonly used adjuvant therapy due to its effectiveness, and bone resection minimises recurrence but leads to severe functional and aesthetic issues, there is limited data comparing the efficacy of MCS to newer agents like 5-Fluorouracil (5FU) in reducing recurrence. …”
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Design and Evaluation of ADANet: A High-Fidelity Motion Acquisition Framework for Assistive Gesture-Based Interfaces by Md Ettashamul Haque, Atique Tajwar, Akm Azad, Salem A. Alyami, Md Mehedi Hasan

“…To address these limitations, this article presents ADANet — Advanced Disability Assistive Neural Network-driven framework for accelerometer-based gesture recognition, tailored for wearable assistive applications. …”
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Changing minds, saving lives: how training psychological safety transforms healthcare by Philippe Macaire, Clement Buleon, Rebecca Minehart, Viet Vu, Thuy Anh Le, Clara Christina Paula Lua, Frédéric Martin

“…Psychological safety is a crucial component in highly functioning healthcare teams, enabling every member to speak up, take innovative risks and admit mistakes without fear of personal attack or repercussions. …”
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FPGA-accelerated SpeckleNN with SNL for real-time X-ray single-particle imaging by Abhilasha Dave, Cong Wang, James Russell, Ryan Herbst, Jana Thayer

“…The new implementation, while reducing the parameter count to 64.6K (a 98.8% reduction), focuses on maintaining the model's essential functionality for real-time operation, achieving an accuracy of 90%. …”
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Investigating the potential effect of Holothuria scabra extract on osteogenic differentiation in preosteoblast MC3T3-E1 cells by Sineenart Songkoomkrong, Siriporn Nonkhwao, Supawadee Duangprom, Jirawat Saetan, Sirikul Manochantr, Prasert Sobhon, Napamanee Kornthong, Prateep Amonruttanapun

“…Abstract The present medical treatments of osteoporosis come with adverse effects. …”
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Comparison of resting-state alpha frequency and prefrontal cortex activation patterns between elite retired amateur boxers and healthy individuals: an fNIRS and EEG study by Muhammed Sıddık Çemç, Murat Kaldırımcı

“…Methods: Electroencephalography (EEG) measurements were performed in the resting state with eyes open and closed. Functional Near Infrared Spectroscopy (fNIRS) recordings were taken from the PFC during the presentation of Stroop test stimuli to the participant in block form. …”
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Methodology for staff management assessment efficiency in the medical institutions by Yuliia Opanasiuk, Monika Grabowska, Olena Volovyk

“…This paper considers human resources to be important for the effective functioning and development of the organization in current socio-economic conditions. …”
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Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla by Paak Rewthamrongsris, Suphalak Phothichailert, Uraiwan Chokechanachaisakul, Prim Janjarussakul, Chatvadee Kornsuthisopon, Lakshman Samaranayake, Thanaphum Osathanon

“…Abstract Background Simvastatin modulates numerous stem cell functions, including stemness maintenance and differentiation. …”
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AutoTarget: Disease-Associated druggable target identification via node representation learning in PPI networks by Hyunseung Kong, Inyoung Kim, Byoung-Tak Zhang

“…Visualization of embedding vectors using t-SNE revealed clear separations between functional protein families, including nuclear proteins, growth factor receptors, and the G proteins within the kinase proteins. …”
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Gustometry in various variants of bronchial asthma: Sensitivity thresholds for bitter and sweet tast by V. N. Mineev, M. A. Nyoma, L. N. Sorokina, P. V. Bryukhanova, D. E. Koksharova

“…The receptors for bitter and sweet taste, may, apparently, have opposite functions, but in available literature there is no data on the balance of sensitivity for bitter and sweet tastes in the same patients with bronchial asthma. …”
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