Carbon nanotubes in brain targeted drug delivery: A comprehensive review by Sourav Das, Sukanta Roy, Subhas Chandra Dinda, Anirbandeep Bose, Chinmaya Mahapatra, Biswajit Basu, Bhupendra Prajapati

“…Carbon nanotubes (CNTs) have emerged as a promising strategy for overcoming this obstacle, providing an innovative platform for targeted drug delivery to the brain. This review presents a detailed analysis of CNTs as drug carriers, with a particular emphasis on their application in brain tumor treatment. …”
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A case report of percutaneous direct injection of N-butyl-2-cyanoacrylate (NBCA) to treat a pancreatic duodenal stump leak after a simultaneous pancreas and kidney transplantation by Chisato Shirakawa, Masaaki Watanabe, Tsuyoshi Shimamura, Yasuyuki Koshizuka, Norio Kawamura, Ryoichi Goto, Takeshi Soyama, Daiki Iwami, Kiyohiko Hotta, Akinobu Taketomi, Daisuke Abo

“…The patient was discharged on postoperative day 93 with good-functioning pancreas and kidney grafts. One and a half years after the operation, the patient was found to have acute graft pancreatitis and a leak from the duodenal stump of the pancreas graft due to a paralytic neurogenic bladder. …”
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Indocyanine green fluorescence to ensure perfusion in middle segment-preserving pancreatectomy: a case report by Tomohiro Iguchi, Norifumi Iseda, Kosuke Hirose, Mizuki Ninomiya, Takuya Honboh, Takashi Maeda, Fumi Sawada, Yu-ichi Tachibana, Tetsuro Akashi, Naotaka Sekiguchi, Noriaki Sadanaga, Hiroshi Matsuura

“…Abstract Background Middle segment-preserving pancreatectomy (MSPP) is an alternative to total pancreatectomy that allows for the preservation of the endocrine and exocrine functions of the pancreas. However, maintaining perfusion to the pancreatic remnant is of critical importance. …”
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Information Metasurface Technology-enabled Integrated Passive Wireless Communication System Based on Synthetic Aperture Radar by Hua LI, Kaiyu LIU, Yunkai DENG, Zhenning LI, Chao LUO, Jichen LI, Taoyu REN, Yao CHEN, Kaijiang XU

“…The integration technology of satellite communications and spaceborne Synthetic Aperture Radar (SAR) remote sensing aims to combine communication and remote sensing functionalities, enabling simultaneous data transmission and remote sensing imaging to meet the demands of efficient, covert, and secure information transfer, enhancing system multifunctionality. …”
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α-GalCer-LNP ehanced mRNA delivery and activates natural killer T cells for superior tumor immunotherapy by Kexin Zhang, Zhen Xu, Zexiu Xiao, Fei Cao, Jing Wang, Yuandong Xu, Winson M.J. Ma, Sihui Long, Gao-Feng Zha

“…Mechanistic studies showed that G-LNP preferentially targets CD11c+ DC in the lymph nodes, facilitating coordinated antigen presentation and innate immune activation. This five-component engineering strategy establishes a versatile platform to enhance the functionality of LNPs for the development of next-generation cancer vaccines.…”
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Indole-3-propionic acid enhances glycolytic myofiber formation in piglets through PI3K-mTOR activation and gut microbiota-driven tryptophan metabolic alteration by Yezi Kong, Qi Wang, Jing Wang, Xiaoyu Qiu, Yong Yang, Jingbo Liu, Feiyun Yang, Renli Qi

“…Indole-3-propionic acid (IPA) is a metabolite of tryptophan produced by gut bacterial catabolism that has a variety of functions, including anti-inflammatory, free radical scavenging, and regulation of glucose metabolism. …”
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Multi‐Annual Inventorying of Retrogressive Thaw Slumps Using Domain Adaptation by Yiling Lin, Xie Hu, Haoyu Lu, Fujun Niu, Gengnian Liu, Lingcao Huang, Shanghang Zhang, Jifu Liu, Yunhuai Liu

“…We introduced the Tversky loss and the automatic adjustment of weights for multiple loss functions to suppress false positives and to improve the generalization of TADA. …”
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Investigation of Efficient Mixing Enhancement in a Droplet Micromixer with Short Mixing Length at Low Reynolds Number by Yuanfang Qiu, Xueze Zhang, Mengzhen Hao, Xu Yin, Mengling Zhou, Shichao Ma, Yuanting Zhang, Naiqian Jiang, Li Xie, Xichen Yuan, Honglong Chang

“…However, at the micro-scale, the flow typically presents as laminar flow due to low Reynolds numbers, rendering rapid mixing challenging. …”
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Meloxicam mitigated methylglyoxal-induced glycative stress in rats by Talha Fayyaz, Ghulam Abbas, Hammad Ahmed, Najeeb Khatian, Shumaila Usman, Uzair Nisar, Noor Ain, Yamna Khurshid, Syed Ali

“…Afterward, the cognitive (Morris Water Maze), liver (LFT), and kidney (Creatinine) functioning were evaluated. The expression of genes of interest (TNF-α, RAGE, BACE, Glyoxalase, and VEGF) were estimated (qPCR) in the liver, brain, and kidney along with histopathology (H&E staining). …”
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Coupling Analysis of “Demand–Satisfaction” for Rural Public Service Facilities Based on the Kano Model with Importance–Performance Analysis: A Case Study of Gaoqing County, Zibo Ci... by Xinlei Wang, Jinwei Wen, Jing He, Mengying Wang, Keju Liu, Jinghua Dai, Dingqing Zhang, Dian Zhou, Yingtao Qi

“…In the context of people-oriented and high-quality development, improving the quality of rural public service facilities is an important way to promote rural revitalization. However, at present, there are problems such as imbalanced resource allocation, single service functions, and low service quality in regard to rural public service facilities in general, and the contradiction between supply and demand is becoming increasingly prominent. …”
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Positive resonance: Successful interpersonal emotion regulation facilitated relationship closeness by enhanced inter-brain synchronization by Tongtong Zhu, Xiaoxuan Zhang, Luyao Jin, Linzi Wang, Yanmei Wang

“…It remains unclear whether successful IER could facilitate interpersonal relationship closeness (IRC). The present study aimed to explore whether successful IER, based on two typical strategies—cognitive reappraisal (CR) and expressive suppression (ES)—for down-regulating the target's negative emotions, could enhance IRC among friend dyads, and to identify the underlying neural correlates of this process using functional near-infrared spectroscopy system. …”
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Resistance of breast cancer cells to all-trans retinoic acid is associated with a decrease in the basal level of nuclear receptor <i>RARα</i> expression and induction of cytochrome... by A. D. Enikeev, A. V. Komelkov, N. V. Elkina, M. E. Akselrod, S. A. Kuzmichev, E. M. Tchevkina

“…Retinoic acid (RA) is a key regulator of cell differentiation and a critical player in such systemic processes in the body as embryonic development, immune system cell maturation and functioning, tissue remodeling and several others. This compound displays an antitumor activity due to its ability to stimulate differentiation, induce apoptosis  and inhibit proliferation of malignant cells. …”
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Nanomaterials in the treatment of degenerative intellectual and developmental disabilities by Humaira Aslam, Ali Umar, Nazia Nusrat, Manel Mansour, Aman Ullah, Shehla Honey, Muhammad Jehanzeb Sohail, Mustansar Abbas, Muhammad Waseem Aslam, Misbah Ullah Khan

“…Due to their size, surface characteristics, and ability to be functionalized, these carriers can directly deliver therapeutics across what is considered one of the main barriers to central nervous system (CNS) treatment, the blood-brain barrier (BBB). …”
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Whole-genome re-sequencing association study on body size traits at 10-weeks of age in Chinese indigenous geese by Guobo Sun, Guobo Sun, Hongchang Zhao, Hongchang Zhao, Xiaohui Mu, Xiaohui Mu, Xiaoming Li, Jun Wang, Jun Wang, Mengli Zhao, Mengli Zhao, Rongchao Ji, Hailing Lv, Yang Li, Chao Chen, Jia Xie, Wei Zhang, Xiujun Duan, Shanyuan Zhu, Jian Wang, Jian Wang, Jian Wang

“…The identification of these novel SNPs and candidate genes associated with 10-week-old body size traits in geese presents valuable insights for future molecular breeding endeavors and the elucidation of underlying mechanisms governing body size trait formation in goose.…”
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Mechanisms and engineering of a miniature type V-N CRISPR-Cas12 effector enzyme by Wenhan Fu, Jiacheng Ma, Zhipeng Wang, Na Tang, Deng Pan, Mengjiao Su, Zhaowei Wu, Jianhua Gan, Quanjiang Ji

“…Abstract Type V CRISPR-Cas12 systems are highly diverse in their functionality and molecular compositions, including miniature Cas12f1 and Cas12n genome editors that provide advantages for efficient in vivo therapeutic delivery due to their small size. …”
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Evaluation of Mo99 and Tc99m Productions Based on a High-Performance Cyclotron by J. Esposito, G. Vecchi, G. Pupillo, A. Taibi, L. Uccelli, A. Boschi, M. Gambaccini

“…In order to get a comprehensive map of radionuclides expected, a detailed theoretical investigation has been carried out using the TALYS-TENDL 2012 excitation functions extended up to (p,6n), (p,p5n), and (p,2p4n) levels. …”
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Purification and Oxidative Scavenging of Total Alkaloids of <i>Piperis longi fructus</i> Based on Adsorption Kinetics and Thermodynamic Theory by Lirong Lu, Dezhi Shi, Nuo Chen, Chengchao Wu, Hang Zhang, Shaohui Zhong, Jing Ji, Yunfeng Zheng, Jianming Cheng, Shiwen Huang, Taoshi Liu

“…Subsequently, the resin was loaded into the column and eluted with 70% ethanol at a flow rate of 2 BV/h for 10 BV to achieve desorption. The present study provides a more efficient method for the enrichment of the total alkaloidal components of <i>Piperis longi fructus</i>, which will lay the foundation for applications in food additives or functional foods in the future.…”
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Three-Dimensional Real-Scene-Enhanced GNSS/Intelligent Vision Surface Deformation Monitoring System by Yuanrong He, Weijie Yang, Qun Su, Qiuhua He, Hongxin Li, Shuhang Lin, Shaochang Zhu

“…To address these issues, this paper presents a 3D real-scene (3DRS)-enhanced GNSS/intelligent vision surface deformation monitoring system. …”
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Intragastric administration of short chain fatty acids greatly reduces voluntary ethanol intake in rats by María Elena Quintanilla, Daniela Santapau, Eugenio Diaz, Ignacio Valenzuela Martinez, Nicolas Medina, Glauben Landskron, Antonia Dominguez, Paola Morales, David Ramírez, Marcela Hermoso, Belén Olivares, Pablo Berríos-Cárcamo, Marcelo Ezquer, Mario Herrera-Marschitz, Yedy Israel, Fernando Ezquer

“…Among the different protective molecules that could mediate this communication, short chain fatty acids (SCFAs) have emerged as attractive candidates, since these gut microbiota-derived molecules have multi-target effects that could normalize several of the functional and structural parameters altered by chronic alcohol abuse. …”
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USP51/GRP78/ABCB1 axis confers chemoresistance through decreasing doxorubicin accumulation in triple-negative breast cancer cells by Yang Ou, Kun Zhang, Qiuying Shuai, Chenyang Wang, Huayu Hu, Lixia Cao, Chunchun Qi, Min Guo, Zhaoxian Li, Jie Shi, Yuxin Liu, Siyu Zuo, Xiao Chen, Yanjing Wang, Mengdan Feng, Hang Wang, Peiqing Sun, Yi Shi, Guang Yang, Shuang Yang

“…However, the underlying mechanisms and signaling networks involved in USP51-mediated regulation of malignant phenotypes remain largely unknown. The present study provides evidence of USP51's functions as the prominent DUB in chemoresistant triple-negative breast cancer (TNBC) cells. …”
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