Bio-barrier-adaptable biomimetic nanomedicines combined with ultrasound for enhanced cancer therapy by Juan Guo, Xueting Pan, Qingyuan Wu, Ping Li, Chaohui Wang, Shuang Liu, Haoyuan Zhang, Zezhong Huang, Xiaozhou Mou, Huiyu Liu, Jiajia Xue

“…This design conferred dual functionality: (1) enhanced tumor accumulation and immune evasion by exploiting homologous cell-cell interactions and mimicking “self” markers, thereby effectively bypassing macrophage clearance and surpassing the limitations of traditional targeted drug delivery; and (2) amplified ultrasound (US)-mediated intratumoral penetration. …”
Get full text

A Nextflow pipeline for T-cell receptor repertoire reconstruction and analysis from RNA sequencing data by Teresa Rubio, Maria Chernigovskaya, Susanna Marquez, Cristina Marti, Paula Izquierdo-Altarejos, Amparo Urios, Carmina Montoliu, Vicente Felipo, Ana Conesa, Victor Greiff, Sonia Tarazona

“…The provided computational pipeline functions as a resource to facilitate TCR profiling from RNA-seq data boosting immunophenotype analyses of immunological diseases.…”
Get full text

How do we know that they actually use it? Exploring measures of adherence to stress management strategies in university students: A systematic review by Laurianne Bastien, Sohyun Cho, Julia Petrovic, Bassam Khoury, Elana Bloom, Nancy Heath

“…University students are reporting high levels of stress that interfere with their academic performance and daily functioning. In response, higher education institutions have increasingly implemented digital, self-guided stress management resources to provide students with accessible mental health support. …”
Get full text

Reduced low-traumatic access thyroidectomy with central neck dissection by A. V. Shabunin, D. D. Dolidze, S. O. Podvyaznikov, K. V. Mel’nik, R. B. Mumladze, A. V. Vardanyan, I. N. Lebedinskiy, Z. A. Bagateliya, N. N. Gogitidze

“…Materials and methods. In this paper we present the treatment results of 76 patients with differentiated TC, who received surgical treatment at S.P. …”
Get full text

Endoscopic spine surgery for obesity-related surgical challenges: a systematic review and meta-analysis of current evidence by Wongthawat Liawrungrueang, Watcharaporn Cholamjiak, Peem Sarasombath, Yudha Mathan Sakti, Pang Hung Wu, Meng-Huang Wu, Yu-Jen Lu, Lo Cho Yau, Zenya Ito, Sung Tan Cho, Dong-Gune Chang, Kang Taek Lim

“…Obesity presents significant challenges in spinal surgery, including higher rates of perioperative complications, prolonged operative times, and delayed recovery. …”
Get full text

Clinical characteristics and comparative analysis of PD-1/PD-L1 inhibitor-induced pituitary dysfunction versus other pituitary disorders by Yan Xiao, Deyue Jiang, Shengjie Wang, Lei Fu, Lingtong Ye, Erhan Zheng, Zhaohui Lv, Yiming Mu, Wenwen Gong, Qinghua Guo

“…Furthermore, some patients with pituitary-irAE exhibited partial or complete functional recovery of the pituitary gland after hormone replacement therapy. …”
Get full text

Smart biomimetic “nano-med-fireman” blocking inflammation and lactate metabolism crosstalk for normalized spatiotemporal photo-immunotherapy by Honglin Huang, Ningxi Li, Li Zeng, Qianyi Zeng, Ziman Yang, Jinyang Shen, Xiaodan Wei, Hong Yang, Dengfeng Wang, Yiyao Liu, Chunhui Wu

“…The immense complexity and interconnectedness of inflammation and metabolism in the primary tumor ecosystem and pre-metastatic niches (PMN) present an enormous challenge for developing advanced nano-medicines for cancer immunotherapy. …”
Get full text

Identifying Potential Urban Greenways by Considering Green Space Exposure Levels and Maximizing Recreational Flows: A Case Study in Beijing’s Built-Up Areas by Tao Liu, Le Yu, Xin Chen, Yunmiao Chen, Xiaomeng Li, Xinyi Liu, Yue Cao, Fan Zhang, Chenggang Zhang, Peng Gong

“…The results showed that the potential greenways network spans 1566.36 km in BBUA, encompassing 93.88% of parks and offering six diverse functions. It can serve 34.39–35.92% of bus recreation passengers, with this ratio tending to be higher on weekends. …”
Get full text

Dual-immunomodulatory effects on RAW264.7 macrophages and structural elucidation of a polysaccharide isolated from fermentation broth of Paecilomyces hepiali by Baoming Tian, Renjian Liu, Qi Li, Hanshan Xu, Ming Cai, Rongfa Guan, Peilong Sun, Kai Yang

“…This study reveals that the fermentation broth of PHP is also a valuable resource and PHP40-2 has the potential to be developed as a novel functional food.…”
Get full text

Additively manufactured conductive and dielectric 3D metasurfaces for independent manipulation of broadband orbital angular momentum by Mengze Li, Jiaqi Cai, Li Deng, Xiaopeng Li, Francesca Iacopi, Yang Yang

“…Lights-out digital manufacturing, a sophisticated multi-material printing technique, facilitates the seamless sintering of silver nanoparticles and acrylate inks, enabling the creation of functional electronic devices. In this study, the LDM process is utilized to prototype intricate 3D metasurface designs. …”
Get full text

Visible light photocatalytic degradation of tetracycline using copper ferrite nanoparticles synthesized via Glycine-Assisted combustion method by A. Dinesh, K. Radhakrishnan, V. Renuga, Rajendra P. Patil, Suriyaprakash Rajadesingu, S. Suthakaran, L. Guganathan, Manikandan Ayyar, Madhappan Santhamoorthy, Lalitha Gnanasekaran, Munawar Iqbal

“…X-ray diffraction (XRD) was used to check the phase’s structure and purity, FT-IR was used to find out what functional groups were present, UV–Vis diffuse reflectance spectroscopy (DRS) was used to look at the optical properties, and scanning electron microscopy (SEM) was used to see the structure’s shape. …”
Get full text

Cloning, Expression, and Bioinformatics Analysis of the <i>AvFD1</i> Gene in <i>Amomum villosum</i> Lour by Duo Wang, Yating Zhu, Shuang Li, Hongyou Zhao, Chongnan Wang, Qianxia Li, Yanfang Wang, Chunyong Yang, Ge Li, Yanqian Wang, Lixia Zhang

“…The obtained sequence establishes essential molecular data for subsequent functional validation of <i>AvFD1</i> in <i>A. villosum</i>.…”
Get full text

Prospects of Predicting the Polar Motion Based on the Results of the Second Earth Orientation Parameters Prediction Comparison Campaign by Tomasz Kur, Justyna Śliwińska‐Bronowicz, Malgorzata Wińska, Henryk Dobslaw, Jolanta Nastula, Aleksander Partyka, Santiago Belda, Christian Bizouard, Dale Boggs, Sara Bruni, Lue Chen, Mike Chin, Sujata Dhar, Robert Dill, PengShuo Duan, Jose M. Ferrandiz, Junyang Gou, Richard Gross, Sonia Guessoum, Songtao Han, Robert Heinkelmann, ChengLi Huang, Christopher Irrgang, Jacek Kudrys, Jia Li, Marcin Ligas, Lintao Liu, Weitao Lu, Volker Mayer, Wei Miao, Maciej Michalczak, Sadegh Modiri, Michiel Otten, Todd Ratcliff, Shrishail Raut, Jan Saynisch‐Wagner, Matthias Schartner, Erik Schoenemann, Harald Schuh, M. Kiani Shahvandi, Benedikt Soja, Xiaoqing Su, Daniela Thaller, Maik Thomas, Guocheng Wang, Yuanwei Wu, CanCan Xu, Xueqing Xu, Xinyu Yang, Xin Zhao, Zhijin Zhou

“…Abstract Growing interest in Earth Orientation Parameters (EOP) resulted in various approaches to the EOP prediction algorithms, as well as in the exploitation of distinct input data, including the observed EOP values from various operational data centers and modeled effective angular momentum functions. Considering these developments and recently emerged new methodologies, the Second Earth Orientation Parameters Prediction Comparison Campaign (2nd EOP PCC) was pursued in 2021–2022. …”
Get full text

Synthesis and Characterization of Nano Chitosan from Vannamei Shrimp Shell (<I>Litopenaeus vannamei</I>) by Dian Wijaya Kurniawidi, Siti Alaa, Eva Nurhaliza, Desti Olga Safitri, Susi Rahayu, Muhamad Ali, Muhamad Amin

“…The FTIR results showed that the synthesized shrimp shells had successfully formed chitin compounds with the appearance of the C-O-C functional group, while the chitosan compounds with the appearance of O-H and N-H groups. …”
Get full text

LabEmbryoCam: An opensource phenotyping system for developing aquatic animals by Ziad Ibbini, Maria Bruning, Sakina Allili, Luke A Holmes, Ellen Tully, Jamie McCoy, Benjamin Larsen, Tony Wilson, Guy Ludford, Jack Barrett-Kelly, John I. Spicer, Oliver Tills

“…Aquatic embryos are natural models for phenomics, due to their small size, taxonomic diversity, ecological relevance, and high levels of temporal, spatial and functional change. Here, we present LabEmbryoCam, an autonomous phenotyping platform for timelapse imaging of developing aquatic embryos cultured in a multiwell plate format, and while optimised for embryos, the instrument is extremely versatile. …”
Get full text

Mesoscale soil moisture measurements along the rover route using the mobile cosmic-ray neutron sensing in the eastern Tibetan Plateau by Yongyong Zhang, Shaoxiong Wu, Wenzhi Zhao, Jianhua Xiao

“…Water resources in the soil play an essential role in hydrological processes and ecosystem functions on the Tibetan Plateau. However, accurately measuring soil moisture distribution in this region presents challenges due to the diverse ecosystem types, complex terrain, and harsh environmental conditions. …”
Get full text

Genetic deletion of the sodium phosphate cotransporter NaPi2a ameliorates heart failure in mice by Hiroko Yamauchi-Sawada, Tomoharu Ida, Masashi Nakamura, Minato Umehara, Natsuko Okuno-Ozeki, Itaru Nakamura, Yayoi Matoba, Atsushi Minamida, Yasuto Sunahara, Tomohiro Nakata, Kunihiro Nakai, Aya Yagi-Tomita, Noriko Uehara-Watanabe, Noriyuki Yamashita, Yuhei Kirita, Keiichi Tamagaki, Benjamin D. Humphreys, Satoaki Matoba, Tetsuro Kusaba

“…Sodium-phosphate co-transporter 2a (NaPi2a) is predominantly expressed in the apical membrane of proximal tubular epithelia and functions to reabsorb filtered phosphate and sodium. …”
Get full text

KPNA5 Suppresses Malignant Progression of Ovarian Cancer Through Importing the PTPN4 Into the Nucleus by Yanming Hu, Jing Zhou, Xinru Ling, Kun Zhao, Peng Huang, Max Gao, Xiaoqing Li, Ming Sun, Yanfen Zou, Guannan Feng

“…Conclusions Our findings identify KPNA5 as a tumor suppressor in OC, presenting a potential therapeutic target for OC treatment.…”
Get full text

Invasive laser acupuncture targeting muscle: a novel approach to protect dopaminergic neurons and reduce neuroinflammation in a brain of Parkinson’s disease model by Halin Jeon, Ju-Young Oh, Sora Ahn, Mijung Yeom, In Jin Ha, Hong-Seok Son, Seong-Eun Park, Juhan Park, Eugene Huh, In-Yeop Baek, Min-Ho Nam, Changsu Na, Myung Sook Oh, Hi-Joon Park

“…Abstract Parkinson’s disease (PD) affects 1–2% of the global population and presents significant therapeutic challenges. Due to the limitations of existing treatments, there is a pressing need for alternative approaches. …”
Get full text

MXene/MOF-Derived Composites with Multidimensional Nanostructures: Synthesis Methods, Performance, and Applications in the Field of Energy Storage by Shufan Feng, Shilong Wen, Rutao Wang, Xiaokun Yang, Xiangsen Yuan, Yuxuan Liu, Jingyun Ma, Zhaoqiang Li

“…The integration of MXene, characterized by its abundant surface functional groups (-O, -OH, -F) and exceptional electrical conductivity, with MOF-derived materials presents a viable strategy to address these challenges. …”
Get full text