Multidimensional pain profiling in people living with obesity and attending weight management services: a protocol for a longitudinal cohort study by Catherine Blake, Carel W le Roux, Keith M Smart, Catherine M Doody, Francis M Finucane, Brona M Fullen, Jean O’Connell, Natasha S Hinwood, Colin Dunlevy, Clare Gilsenan, Grainne O'Donoghue

“…Obesity is associated with increased self-reported pain intensity and pain-related disability, reductions in physical functioning and poorer psychological well-being. People living with obesity tend to respond less well to pain treatments or management compared with people living without obesity. …”
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Cord blood therapy for pure red cell aplasia after allogeneic hematopoietic stem cell transplantation: case series and review by Zhen Li, Sujing Zhuang, Ruirui Gui, Binglei Zhang, Wenli Zhang, Juan Wang, Yingling Zu, Fei Yang, Fei Yang, Xiangke Xin, Yanyan Liu, Yanli Zhang, Baijun Fang, Fengkuan Yu, Huifang Zhao, Wei Li, Yongping Song, Yongping Song, Jian Zhou

“…Umbilical cord blood (UCB) and mesenchymal stem cells (MSCs) have been widely used in hematological and immune system diseases due to their hematopoietic reconstitution and immunomodulatory functions. However, few studies about using UCB and MSCs to treat PRCA after allo-HSCT have been reported.Case presentationIn this report, different cell therapy regimens of UCB and MSCs were used in 3 acute myeloid leukemia (AML) patients diagnosed with PRCA after allo-HSCT. …”
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Multimodal approaches and AI-driven innovations in dementia diagnosis: a systematic review by Revati M. Wahul, Sarita Ambadekar, Deepesh M. Dhanvijay, Mrinai M. Dhanvijay, Manisha A. Dudhedia, Varsha Gaikwad, Bhavana Kanawade, J. R. Pansare, Balaji Bodkhe, S. H. Gawande

“…Abstract Neurodegenerative disorders, such as dementia, present some of the most pressing challenges in the field of medicine today. …”
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Effects of magnetic field pretreatment and chloride salt stress on physio-biochemical changes and γ-aminobutyric acid accumulation in germinated brown rice by Ying Zhu, Shengqi Tan, Chong Xie, Dandan Li, Pei Wang, Runqiang Yang

“…Gamma-Aminobutyric Acid (GABA), abundantly present in germinated brown rice, has attracted significant attention due to its multiple active functions on the human body. …”
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Metabolomic insights into the prebiotic and metabolic regulatory properties of ellagic acid and urolithins on probiotic-like bacteria in vitro by Yang Yang, Ke Wang, Jia-Chi Chiou, Danyue Zhao

“…Overall, this study provides in-depth understanding on how dietary polyphenols with prebiotic properties regulate the growth and metabolic functions of probiotic-like bacteria.…”
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MicroRNA-145 in urologic tumors: biological roles, regulatory networks, and clinical translation by Lifeng Gan, Lifeng Gan, Lifeng Gan, Wei Li, Wei Li, Wei Li, Qi Chen, Qi Chen, Qi Chen, Le Cheng, Le Cheng, Le Cheng, Fangtao Zhang, Fangtao Zhang, Fangtao Zhang, Haidong Zhong, Haidong Zhong, Haidong Zhong, Yiran Lu, Liying Zheng, Biao Qian, Biao Qian

“…Among them, miR-145, as a regulatory molecule with significant anticancer properties, presents unique expression characteristics and functional mechanisms in urological tumours. …”
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Detecting Postural Instability in Parkinson’s Disease From IMU-Based Objective Measures by Kendal Smith, Diego Torricelli, Miguel Gonzalez-Sanchez, Javier Ricardo Perez-Sanchez, Elisa Luque-Buzo, Francisco Grandas, Juan Miguel Marin, Jorge Andres Gomez-Garcia

“…Parkinson’s Disease (PD) is a progressive neurological disorder that affects both motor and non-motor functions. A critical aspect of PD is postural instability, which is associated with a higher risk of falls and a significant decline in mobility. …”
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Vitamin D and depression in adults: A systematic review by Vlad Dionisie, Mihnea Alexandru Gaman, Cristina Anghele, Mihnea Costin Manea, Maria Gabriela Puiu, Iulia-Ioana Stanescu-Spinu, Octavian-Ilarian Baiu, Florian Antonescu, Mirela Manea, Adela Magdalena Ciobanu

“…Therefore, the present study aimed to systematically review the available research investigating the association between vitamin D levels and the onset of depression. …”
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Geography, Antimicrobial Resistance, and Genomics of <i>Salmonella enterica</i> (Serotypes Newport and Anatum) from Meat in Mexico (2021–2023) by Eduardo Canek Reynoso, Enrique Jesús Delgado-Suárez, Cindy Fabiola Hernández-Pérez, Yaselda Chavarin-Pineda, Elizabeth Ernestina Godoy-Lozano, Geny Fierros-Zárate, Omar Alejandro Aguilar-Vera, Santiago Castillo-Ramírez, Luz del Carmen Sierra Gómez-Pedroso, Luisa María Sánchez-Zamorano

“…Considering unique genes, <i>Salmonella</i> Anatum and Newport showed a notorious abundance of genes with functions related to replication, recombination, and repair. …”
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Case Report: Achieving ankle joint stability through early intervention in an 8-year-old with congenital fibular hemimelia by Yanhong Ma, Yanhong Ma, Na Pan, Na Pan, Gang Peng, Gang Peng, Rui Yang, Rui Yang

“…Most pediatric patients require at least two surgical procedures, with the initial stage involving ankle reconstruction surgery to achieve joint stability, followed by subsequent limb lengthening procedures to correct limb length discrepancies between the lower extremities.Presentation of caseHere, we report for the first time a case of CFH with complete absence of fibula in a pediatric patient who achieved ankle stability through early application of splinting to maintain the right ankle in a functional position, thereby correcting valgus deformity and obviating the need for ankle reconstruction surgery. …”
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Bright-Field Multiplex Immunohistochemistry in Swine PCV2 and PRRSV Lymphadenopathies by Giulia D’Annunzio, Luisa Vera Muscatello, Chiara Tugnoli, Stefano Pesaro, Andrea Luppi, Michelangelo Fiorentino, Tania Franceschini, Alessia Grillini, Gianluca Rugna, Giuseppe Sarli, Luciana Mandrioli

“…Multiplex immunostaining (mIHC) allows the simultaneous detection of multiple antigenic targets within the same tissue section, providing a deeper understanding of spatial variation in cellular distribution. The aim of the present study is to apply this technique to examine the spatial variation of lymphocyte populations in swine lymph nodes during PCV2-SD and PRRSV lymphadenopathy compared with reactive lymphoid hyperplasia. …”
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Deep reinforcement learning agents for dynamic spectrum access in television whitespace cognitive radio networks by Udeme C. Ukpong, Olabode Idowu-Bismark, Emmanuel Adetiba, Jules R. Kala, Emmanuel Owolabi, Oluwadamilola Oshin, Abdultaofeek Abayomi, Oluwatobi E. Dare

“…The implementation was done in the Radio Frequency Reinforcement Learning (RFRL) Gym, a training environment of the RF spectrum designed to provide comprehensive functionality. Evaluations show that the DQN model achieves a 96.34 % interference avoidance rate compared to 95.97 % of QRDQN. …”
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Synthesis, preclinical evaluation and pilot clinical study of a P2Y12 receptor targeting radiotracer [18F]QTFT for imaging brain disorders by visualizing anti-inflammatory microgli... by Bolin Yao, Yanyan Kong, Jianing Li, Fulin Xu, Yan Deng, Yuncan Chen, Yixiu Chen, Jian Chen, Minhua Xu, Xiao Zhu, Liang Chen, Fang Xie, Xin Zhang, Cong Wang, Cong Li

“…As the brain's resident immune cells, microglia perform crucial functions such as phagocytosis, neuronal network maintenance, and injury restoration by adopting various phenotypes. …”
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Investigation of cell development and tissue structure network based on natural Language processing of scRNA-seq data by Suwen Wei, Yuer Lu, Peng Wang, Qichao Li, Jianwei Shuai, Qi Zhao, Hai Lin, Yuming Peng

“…Methods Inspired by NLP, we present a novel scRNA-seq analysis method that treats genes as analogous to words. …”
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Molecular turn in Yersinia pestis pathogenesis: implications of the gppA frameshift for bacterial survival in human macrophage by Hongyan Chen, Shiyang Cao, Yazhou Zhou, Tong Wang, Yang Jiao, Yafang Tan, Yarong Wu, Yifan Ren, Yajun Song, Jing-Ren Zhang, Zongmin Du, Ruifu Yang

“…This frameshift mutation of gppA is present in all the evolutionary branches formed by the modern Y. pestis strains responsible for the plague pandemics, while the relative ancient microtus strains express a functional GppA showing high activity in catalyzing pppGpp to ppGpp conversion. …”
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Successful operative treatment of neglected pure Chopart joint dislocation: Two case reports and literature review by Vasović Draško, Mičeta Lazar, Čučaković Filip, Jevtić Aleksandar, Jeremić Danilo, Slavković Nemanja

“…Despite the delayed diagnosis and postponed operative treatment, the functional outcomes of pure CJD treated by open reduction and percutaneous K-wiring can be satisfactory. …”
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From anthropological transfer to children’s emotional health through motor stories by Mónica Aznar-Cebamanos, Mónica Aznar-Cebamanos, Alberto García-Barrios, Alberto García-Barrios, Alberto García-Barrios, Emilio Royo-Ortín, Emilio Royo-Ortín, Carlos Peñarrubia-Lozano, Carlos Peñarrubia-Lozano, Jaime Whyte-Orozco, Jaime Whyte-Orozco, Jaime Whyte-Orozco, Ana Isabel Cisneros-Gimeno, Ana Isabel Cisneros-Gimeno, Ana Isabel Cisneros-Gimeno

“…The development of the prefrontal cortex, which occurs significantly during childhood and adolescence, is closely linked to the formation of executive functions and the establishment of the basis for future behavior. …”
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ZmZFP2 encoding a C4HC3-type RING zinc finger protein regulates kernel size and weight in maize by Long Zhang, Qilei Wang, Wenyu Li, Qi Zheng, Miaomiao Fu, Han Wang, Xinyu Li, Yan Wang, Lingwei Hu, Weigang Yao, Lifeng Wang, Huiyong Li, Yongbin Dong, Yongrui Wu, Yuling Li

“…Together, these findings demonstrate that ZmZFP2 is a key regulator of maize kernel size and weight, functioning through its E3 ubiquitin ligase activity and interactions with various metabolic pathways. …”
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Music and movement therapy improves quality of life and attention and associated electroencephalogram changes in patients with attention-deficit/hyperactivity disorder by Mei-Wen Lee, Ni-Jung Yang, Hin-Kiu Mok, Rei-Cheng Yang, Yi-Hung Chiu, Lung-Chang Lin

“…Methods: The present study investigated the effects of an 8-week music and movement intervention in 13 children with ADHD. …”
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Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources by Magdalena Mititelu, Dumitru Lupuliasa, Sorinel Marius Neacșu, Gabriel Olteanu, Ștefan Sebastian Busnatu, Andreea Mihai, Violeta Popovici, Nicoleta Măru, Steluța Constanța Boroghină, Sebastian Mihai, Corina-Bianca Ioniță-Mîndrican, Alexandru Scafa-Udriște

“…These bioactive compounds are not randomly distributed but are present in foods humans have consumed together historically. …”
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