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  1. 37541

    Issues of Interpretation and Application of the Notion of “International Legal Legitimation” by A. M. Korzhenyak

    Published 2025-01-01
    “…In the process of adapting to the changing realities of geopolitics and international law, collective legitimation has become one of the main political functions of the UN as a means of politically significant approval (or disapproval) of the behaviour and positions of states as consistent with international law and at the same time meeting the needs of the present, a means of recognising them as legitimate (or illegitimate). …”
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  2. 37542

    YOLOv8-Based Estimation of Estrus in Sows Through Reproductive Organ Swelling Analysis Using a Single Camera by Iyad Almadani, Mohammed Abuhussein, Aaron L. Robinson

    Published 2024-10-01
    “…Using custom distance functions, we computed the distances for each measurement dimension and aggregated them to determine the overall similarity. …”
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  3. 37543

    Immune-related gene characterization and biological mechanisms in major depressive disorder revealed based on transcriptomics and network pharmacology by Shasha Wu, Shasha Wu, Qing Jiang, Jinhui Wang, Jinhui Wang, Daming Wu, Yan Ren

    Published 2024-12-01
    “…WGCNA revealed 12 co-expression modules, with modules “darked”, “darkurquoise” and “light yellow” showing significant positive associations with MDD. Functional enrichment pathway analysis indicated that these differential genes were associated with immune functions. …”
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  4. 37544

    Research progress and prospect of cooling technology for drilling fluid in deep and ultra-deep wells by Chao ZHANG, Jinsheng SUN, Xianbin HUANG, Kaihe LÜ, Jintang WANG, Jian LI, Yuan GENG, Juan HE, Jiajun Dai

    Published 2025-06-01
    “…These extreme thermal conditions considerably threaten the stability, functionality, and reliability of drilling fluids that are essential to successful drilling. …”
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  5. 37545
  6. 37546

    Mortality and Graft Failure With Medical Management Alone Versus Revascularization After Coronary Angiography Among Kidney Transplant Recipients: A Population-Based Study by Labib I. Faruque, Robert R. Quinn, Pietro Ravani, Tyrone G. Harrison, Brenda Hemmelgarn, Stephen Wilton, Alix Clarke, Matthew T. James, Ngan N. Lam

    Published 2025-07-01
    “…Patients: We included adult, kidney-only transplant recipients between January 1997 and March 2015 who survived at least 1-year post-transplant with a functioning graft and had a coronary angiography during follow-up. …”
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  7. 37547

    Práticas de gestão no desenvolvimento de produtos em empresas de autopeças Management practices in product development in autoparts industry by José Carlos de Toledo, Sérgio Luis da Silva, Dário Henrique Alliprandini, Manoel Fernando Martins, Fernanda Menezes Ferrari

    Published 2008-01-01
    “…Some of the main findings on the practices are: widespread dissemination and use of reference models for PDP partially implemented; methods and techniques for PDP Management are applied with weak inter functional integration; development team carries out the PDP activities; functional structure is still widely used; the follow-source projects are the most common type, while platform projects were also identified (average of 25% of carry out projects); and the first tier suppliers are the ones that more use practices of international pattern of PDP management. …”
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  8. 37548

    Leflunomide monotherapy in patients with early rheumatoid arthritis: Results of the Russian national Arava mono study by Rimma Mikhailovna Balabanova, Yu A Olyunin

    Published 2012-06-01
    “…The efficiency of the treatment was evaluated by the European League Against Rheumatism (EULAR) classification criteria using DAS 28 scores, by the ACR criteria, and functional changes using HAQ scores and quality of life using the EQ-5D questionnaire. …”
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  9. 37549

    Socioeconomic inequalities in patient-reported outcome measures among total hip and knee arthroplasty patients: a comprehensive analysis of instruments and domains by Joshua M. Bonsel, Max Reijman, Erin M. Macri, Jan A. N. Verhaar, Liza N. van Steenbergen, Gouke J. Bonsel

    Published 2025-05-01
    “…Conclusions Deprived THA/TKA patients have poorer pre- and postoperative health, which was primarily related to worse functioning and pain; the clinical relevance of these differences remain uncertain. …”
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  10. 37550

    A REMARKABLE FEATURE OF BIODIVERSITY OF THE COASTAL, MARINE AND ISLAND ECOSYSTEMS OF THE CASPIAN SEA. A NEW LOOK AT THE AGE OF ISLANDS AND LEVEL MODE by G. M. Abdurahmanov, A. A. Teymurov

    Published 2014-10-01
    “…The last only switched on at night.Location of traps recorded by GPS-navigator. Traps Barbera functioned throughout the expedition period. Removal of the collected material was performed at intervals of 3 days. …”
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  11. 37551

    Case Study of an Integrated Design and Technical Concept for a Scalable Hyperloop System by Domenik Radeck, Florian Janke, Federico Gatta, João Nicolau, Gabriele Semino, Tim Hofmann, Nils König, Oliver Kleikemper, Felix He-Mao Hsu, Sebastian Rink, Felix Achenbach, Agnes Jocher

    Published 2024-11-01
    “…This paper presents the design process and resulting technical concept for an integrated hyperloop system, aimed at realizing efficient high-speed ground transportation. …”
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  12. 37552
  13. 37553

    Early rehabilitation challenges of surgical patients with COVID-19 infection - a single-arm study by Simić-Panić Dušica, Bošković Ksenija, Pantelinac Slobodan, Knežević Aleksandar, Jovićević Predrag, Kozios Apostolos, Janjić Nataša, Nikolić Nikola, Vojnović Larisa, Tomašević-Todorović Snežana

    Published 2024-01-01
    “…These patients exhibited significant functional improvement, which was measured by all tests that assessed rehabilitation outcome at discharge: BI (p < 0.001), MBS (p < 0.001), 6MWT (p < 0.001), and TUG test (p < 0.001). …”
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  14. 37554

    Defects in the necroptosis machinery are a cancer resistance mechanism to checkpoint inhibitor immunotherapy by Katja Steiger, Peter May, Florian Bassermann, Anna Sax, Stefan Enssle, Nardine Soliman, Tatiana Nedelko, Giada Mandracci, Fabian Stögbauer, Laura Joachim, Christof Winter, Nadia El Khawanky, Hendrik Poeck, Simon Heidegger

    Published 2025-05-01
    “…However, it is unclear to which extent functional necroptosis in tumor cells contributes to ICI immunotherapy.Methods With genetically engineered tumor cell lines that lack specific components of the necroptosis machinery (mixed lineage kinase domain-like pseudokinase (MLKL), receptor interacting protein kinase 3 (RIPK3)), we addressed the importance of necroptotic tumor cell death for the efficacy of ICI immunotherapy in murine models. …”
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  15. 37555

    Multimodal versus non-contrast computed tomography for assessment of acute ischaemic stroke: the PRACTISE RCT by Keith W Muir, Salwa El Tawil, Alex McConnachie, Alicia Murray, Ian Ford, Grant Mair, Joanna Wardlaw

    Published 2025-06-01
    “…Treatment decision and delivery times, early neurological recovery and day 90 functional outcomes did not differ significantly between groups. …”
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  16. 37556

    Enhanced intestinal epithelial co-culture model with orbital mechanical stimulation: a proof-of-concept application in food nanotoxicology by Mattia Santoni, Giovanni Piccinini, Giovanni Piccinini, Giovanni Liguori, Maria Roberta Randi, Massimo Baroncini, Liliana Milani, Francesca Danesi

    Published 2025-01-01
    “…IntroductionCurrent in vitro intestinal models lack the mechanical forces present in the physiological environment, limiting their reliability for nanotoxicology studies. …”
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  17. 37557

    Advancements in Antimicrobial Surface Coatings Using Metal/Metaloxide Nanoparticles, Antibiotics, and Phytochemicals by Preetha Ebenezer, S. P. S. N. Buddhika Sampath Kumara, S. W. M. A. Ishantha Senevirathne, Laura J. Bray, Phurpa Wangchuk, Asha Mathew, Prasad K. D. V. Yarlagadda

    Published 2025-07-01
    “…This review evaluates three principal categories of antimicrobial agents utilized in surface functionalization: metal/metaloxide nanoparticles, antibiotics, and phytochemical compounds. …”
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  18. 37558

    Study of the Safety and Toxicokinetic Parameters of the Drug Eladis® in Preclinical Trials with Repeated Administration by A. A. Matichin, M. V. Miroshnikov, A. A. Matichina, V. M. Kosman, M. V. Karlina, E. M. Petrova, A. A. Globenko, E. A. Jain, A. V. Kapashin, A. L. Vladykin, A. S. Kolosov, M. A. Pasko

    Published 2025-04-01
    “…The results indicated no significant effects of the drug on body weight gain, animal behavior in a battery of functional tests, as well as the estimated physiological, biochemical, and hematological parameters. …”
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  19. 37559

    Anti-Inflammatory Cytokine Interleukin-4 Inhibits Inducible Nitric Oxide Synthase Gene Expression in the Mouse Macrophage Cell Line RAW264.7 through the Repression of Octamer-Depen... by Miki Hiroi, Yoshiichi Sakaeda, Hana Yamaguchi, Yoshihiro Ohmori

    Published 2013-01-01
    “…These results suggest that a coactivator/cofactor that functionally interacts with Oct-1 is a molecular target for the IL-4-mediated inhibition of Nos2 and that IL-4-activated Stat6 represses Oct-1-dependent transcription by competing with this coactivator/cofactor.…”
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  20. 37560

    Comparative miRNAome combined with transcriptome and degradome analysis reveals a novel miRNA-mRNA regulatory network associated with starch metabolism affecting pre-harvest sprout... by Longqing Sun, Ting Zhao, Dandan Qin, Jing Dong, Daorong Zhang, Xifeng Ren

    Published 2025-01-01
    “…Abstract Background Pre-harvest sprouting (PHS) is one of the most important problems associated with the severe decrease of yield and quality under disaster weather of continuous rain in wheat harvesting stage. At present, the functions and mechanisms related to the involvement of post-transcriptional regulation has not been studied very clearly in PHS resistance. …”
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