Multianalytical investigation reveals psychotropic substances in a ptolemaic Egyptian vase by Davide Tanasi, Branko F. van Oppen de Ruiter, Fiorella Florian, Radmila Pavlovic, Luca Maria Chiesa, Igor Fochi, Chiaramaria Stani, Lisa Vaccari, Dale Chaput, Giorgio Samorini, Alberto Pallavicini, Sabrina Semeraro, Anastasia Serena Gaetano, Sabina Licen, Pierluigi Barbieri, Enrico Greco

“…We successfully identified the presence of various functional, bioactive, psychotropic, and medicinal substances, shedding light on the diverse components of a liquid concoction used for ritual practices in Ptolemaic Egypt. …”
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Feiyiliu mixture promotes non-small cell lung cancer cells apoptosis via inhibits ZDHHC18-mediated AKT1 phosphorylation by Yuxia Liu, Liang Ding, Shitao Li, Lisha Li, Daijun Xing, Xin Zheng, Baochen Zhou

“…Protein post-translational modification (PTM) is a molecular switch that determines protein diversification and regulates cellular functions, affecting proteins' subcellular localization and three-dimensional structure. …”
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Development of electrochemical nanoprobe for real-time intracellular measurements of Fe2+ during ferroptosis by Yanmei Ma, Xinhao Li, Weikang Hu, Muyang Ruan, Ming Yang, Lingqian Chang, Hongri Gu, Chengzhi Hu

“…The nanoprobes are prepared by coating gold nanoparticles (AuNPs) and poly(3,4-ethylenedioxythiophene) (PEDOT) onto silicon carbide nanowires (SiC NWs), which are subsequently functionalized with ferrocenyl endoperoxide carboxylic acid (FDCA) and integrated with a liquid metal-filled glass nanopipette. …”
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In Vitro Characterization of 3D-Printed PLA/CPO Oxygen Releasing Scaffolds: Mechanical and Biological Properties for Bone Tissue Engineering by Abdullah Mohammed, Alice Tirnoveanu, William Richard Webb, Ammar A. Melaibari, Adnan Memić, Mohammad Aslam, Amr Elshaer, Hany Hassanin, Khamis Essa

“…The addition of oxygen-releasing biomaterials into 3D-printed scaffolds presents a novel approach to enhancing bone scaffolds, yet no in vitro studies have demonstrated the effect of oxygen-generating filaments on scaffold biological and mechanical properties. …”
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Mass Spectrometry-Based Workflow for the Identification and Quantification of Alternative and Canonical Proteins in Pancreatic Cancer Cells by Clémence Guillon, Carole Pichereaux, Ikrame Lazar, Karima Chaoui, Emmanuelle Mouton-Barbosa, Mehdi Liauzun, Edith Gourbeyre, Pinar Altiner, David Bouyssié, Alexandre Stella, Odile Burlet-Schiltz, Serge Plaza, Yvan Martineau, Bertrand Fabre

“…Despite several studies investigating particular AltProts in diseases and demonstrating their importance in such context, we are still missing data on their expression and functions in many pathologies. Among these, pancreatic ductal adenocarcinoma (PDAC) is a particularly relevant case to study alternative proteins. …”
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Dynamic analysis of competitive marketing strategies using differential game models and Runge–Kutta solutions by Awad Talal Alabdala, Asmaa Alhassan, Maan T. Alabdullah, Waleed Adel

“…This study presents a comprehensive mathematical and computational analysis of a competitive market model, incorporating Pontryagin’s Maximum Principle, the Hamiltonian formulation, and the Runge–Kutta (RK4) numerical method. …”
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Resilience-by-Design in 6G Networks: Literature Review and Novel Enabling Concepts by Ladan Khaloopour, Yanpeng Su, Florian Raskob, Tobias Meuser, Roland Bless, Leon Janzen, Kamyar Abedi, Marko Andjelkovic, Hekma Chaari, Pousali Chakraborty, Michael Kreutzer, Matthias Hollick, Thorsten Strufe, Norman Franchi, Vahid Jamali

“…The paper is concluded by presenting a comprehensive list of open problems for future research on 6G resilience.…”
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Intranuclear Crosstalk between Extracellular Regulated Kinase1/2 and Signal Transducer and Activator of Transcription 3 Regulates JEG-3 Choriocarcinoma Cell Invasion and Proliferat... by Diana M. Morales-Prieto, Stephanie Ospina-Prieto, Wittaya Chaiwangyen, Maja Weber, Sebastian Hölters, Ekkehard Schleussner, Justine S. Fitzgerald, Udo R. Markert

“…The regulation of STAT3 phosphorylation at its ser727 binding site, possible crosstalk with intracellular MAPK signaling, and their functional implications are the object of the present investigation. …”
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Serum-Free Medium Supplemented with <i>Haematococcus pluvialis</i> Extracts for the Growth of Human MRC-5 Fibroblasts by Eun-Jeong Koh, Seong-Yeong Heo, Areumi Park, Yeon-Ji Lee, Woon-Yong Choi, Soo-Jin Heo

“…Furthermore, most of the components present in HE were consistent with those found in FBS. …”
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Ephrin-B2 deletion in GABAergic neurons induces cognitive deficits associated with single-nucleus transcriptomic differences in the prefrontal cortex by Peijun Ju, Yu Fang, Siying Xiang, Weidi Wang, Ying Sun, Wei Wang, Yanli Ding, Chao Luo, Ping Jiang, Jianhua Chen

“…Comprehensive identification of cell-type-specific transcriptomic changes in EB2 knockout mice is expected to shed light on potential mechanisms associated with EB2 signaling in cognitive functions. Results Our study captures changes in cell populations in response to EB2 manipulation and reveals previously uncharacterized cell types (CPA6 + inhibitory neurons) in the mPFC. …”
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Insights into the addition of exogenous materials to enhance anaerobic digestion by Adhirashree Vannarath, Yahia H. Ahmad, Toka Mahmoud Farhat, Kyu-Jung Chae, Amina S. Aljaber, Siham Y. Al-Qaradawi

“…This review aims to deepen the understanding of how various promoters influence AD, focusing on their specific functions, dosage effects, underlying mechanisms, and their role in mitigating both conventional inhibitors and emerging contaminants (e.g., antibiotic resistant genes), thereby enhancing the AD process. …”
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Life cycle assessment of additively manufactured elastocaloric Ni-Ti heat pump/refrigeration components and the effect of design geometry on the environmental impact categories by Anesu Nyabadza, Karthikeyan Tamil, Lehar Asip Khan, Sujith S. Kumar, Corné Muilwijk, Greg McNamara, Kevin O'Toole, Lorna Fitzsimons, Dermot Brabazon

“…A 10 x 10 × 55 mm Ni-Ti structure, providing >2 °C temperature span under compressive cycles, served as the functional unit.…”
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Global research landscape and trends of plant-based meat analogs: a bibliometric analysis by Yunting Xie, Linlin Cai, Guanghong Zhou, Chunbao Li

“…Current research topics focused on alternative proteins and their functional and nutritional characteristics, as well as sustainable development. …”
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Protracted Hiccups Induced by Aripiprazole and Regressed after Administration of Gabapentin by Manuel Glauco Carbone, Claudia Tagliarini, Filippo Della Rocca, Walter Flamini, Giovanni Pagni, Beniamino Tripodi, Donatella Marazziti, Icro Maremmani

“…However, our knowledge of the neurotransmitter functioning of the hiccup reflex arc is still limited, and further research is needed to characterize the neurotransmitters involved in hiccups for potential novel therapeutic targets.…”
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Identification of Nogo-B as a potential therapeutic target of osteosarcoma via stereochemically selective covalent probes by Jian Xue, Meng Li, Li Kang, Meiting Wang, Jiabin Yin, Donghui Sun, Yaqi Deng, Qinghua Wei, Jiemin Wong, Tong Zhu, Shunying Liu

“…Altogether, this study presents a novel strategy that couples anti-OS compound screening with target identification and successfully identifies Nogo-B as a potential candidate for targeted OS therapy.…”
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Self‐Catalyzed Chemically Coalescing Liquid Metal Emulsions by Stephanie F. Zopf, Ramón E. Sánchez Cruz, Chloe Kekedjian, Lu Ping, Javier M. Morales Ferrer, Jean Paul Soto Aquino, Rongxuan Xie, Xi Ling, J. William Boley

“…The utility of this ink is demonstrated in a hybrid 3D printing process to create a battery‐integrated light emitting diode array, followed by a nondestructive low temperature heat activation that produces a functional device.…”
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Retrospective Evaluation of Tooth Agenesis in Different Regions of Turkey with Panoramic Radiography by Neşe Oral, Şükran Ayran, Aslıhan Aslan Balcı, Gülay Özdoğan, Selma Ece Karabıyıkoğlu, Hilal Peker Öztürk, Hüseyin Aykut Özyiğit, Ercan Türerer, Gürdoğan Aydın

“…It can result in several complications, impacting functional aspects of the dentition, such as chewing and speech. …”
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Directing HIV-1 for degradation by non-target cells, using bi-specific single-chain llama antibodies by Jord C. Stam, Steven de Maat, Dorien de Jong, Mathia Arens, Fenna van Lint, Lavina Gharu, Mark H. van Roosmalen, Rob C. Roovers, Nika M. Strokappe, Ralf Wagner, Alexander Kliche, Hans J. de Haard, Paul M. van Bergen en Henegouwen, Monique Nijhuis, C. Theo Verrips

“…The requirement of neutralizing antibodies indicates that the antibody mediated removal (clearance) of HIV-1 in itself is not efficient enough in these immune compromised patients. Here we present a novel, alternative approach that is independent of a functional immune system to clear HIV-1, by capturing the virus and redirecting it to non-target cells where it is internalized and degraded. …”
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In vivo evaluation of phage therapy against Klebsiella pneumoniae using the Galleria mellonella model and molecular characterization of a novel Drulisvirus phage species by Gustavo Quispe-Villegas, Gabriela I. Alcántara-Lozano, Diego Cuicapuza, Raúl Laureano, Brenda Ayzanoa, Pablo Tsukayama, Jesús Tamariz

“…Genomic sequencing (Nanopore and Illumina) was used to classify the bacteriophage and identify any resistance genes or virulence factors present in its genome. Functional characterization demonstrated effective lytic activity, favorable burst size (161 PFU/cell), and an optimal MOI of 0.1. …”
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Symptom-specific gut microbial and metabolic profiles in ADHD reveal SCFA deficiency as a Key pathogenic mechanism by Xinyue Wang, Ning Wang, Teng Gao, Yunfan Zhang, Zhao Fu, Yilu Zhao, Yujingwen Huang, Xiangyu Zheng, Xuping Gao, Lin Lu, Li Yang

“…Various taxa, functional pathways, and metabolites associated with specific ADHD symptom domains were identified. …”
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