Comparative Transcriptome Analysis of Temperature-Induced Green Discoloration in Garlic by Ningyang Li, Zhichang Qiu, Xiaoming Lu, Bingchao Shi, Xiudong Sun, Xiaozhen Tang, Xuguang Qiao

“…But the mechanism of low temperature-induced green discoloration is poorly understood. In the present study, the control garlic and three low temperature-treated garlic samples (stored at 4°C with 10, 15, and 40 days, respectively) were used for genome-wide transcriptome profiling analysis. …”
Get full text

Increased Proportion of Dual-Positive Th2–Th17 Cells Promotes a More Severe Subtype of Asthma by Wenjin Sun, Yu Yuan, Lulu Qiu, Qingping Zeng, Jingsi Jia, Xudong Xiang, Aijun Jia, Libing Ma, Shaokun Liu, Bing Xiao

“…Dual-positive Th2–Th17 cells, as newly discovered T-helper cells, have the functions of Th2 and Th17 cells and can coproduce Th2 and Th17 cytokines. …”
Get full text

Medial plantar flap for reconstruction of heel defects after resection of acral lentiginous melanoma: A series of seven cases by Giulia Godoy Takahashi, Renan Diego Américo Ribeiro, Vitor Penteado Figueiredo Pagotto, Caio Augusto Lima de Araújo, Fábio de Freitas Busnardo, Rolf Gemperli

“…The tissues on the sole of the foot have unique characteristics essential for maintaining the limbs functionality. The heel has the most significant weight support and is subjected to the entire soles greatest impact. …”
Get full text

Accumulation of sodium and manganese during litter decomposition of Qinghai spruce (Picea crassifolia) forest in China by Xinning Zhao, Fei Zang, Fangyuan Huang, Na Li, Chuanyan Zhao

“…The biogeochemical cycle of elements is of great significance to plant communities and ecosystem functions. At present, most of the studies on the litter major elements have focused only on C, N, and P, and there are few studies on the biogeochemical cycle of sodium (Na) and manganese (Mn) of forest litter. …”
Get full text

Quantification of rehabilitation for patients with Parkinson’s disease and related disorders using wearable devices; a proof of concept by Hikaru Kamo, Hikaru Kamo, Genko Oyama, Genko Oyama, Genko Oyama, Genko Oyama, Genko Oyama, Genko Oyama, Koichi Nagaki, Koichi Nagaki, Koichi Nagaki, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori

“…Exercise has been reported to help maintain functional abilities and delay disease progression. …”
Get full text

Metabolomics Profiling Reveals Critical Roles of Indoxyl Sulfate in the Regulation of Innate Monocytes in COVID-19 by Liqing He, Yunke Wang, Fang Yuan, Samantha Morrissey, Anne E. Geller, Xiaoling Hu, Raobo Xu, Xipeng Ma, Huang-ge Zhang, Kenneth McLeish, Jiapeng Huang, Xiang Zhang, Jun Yan

“…Moreover, its levels negatively correlated with the strength of co-stimulatory signals and antigen presentation capability in monocytes of COVID-19 patients. …”
Get full text

The Mechanism of Simvastatin-Mediated M1 Macrophage Polarization Contributing to Osteogenesis and Angiogenesis by Siyu Zhu, Yunmeng Tong, Jiaqian Huang, Yuzhu He, Wenqi Fu, Yaran Zang, Huiying Liu

“…Osteogenesis was examined by histological staining, and angiogenic capacity was assessed using functional assays. <b>Results:</b> The present study found that simvastatin decreased M1 macrophage markers (CD86) and stimulated M1 macrophages to express high levels of pro-regenerative cytokines (BMP-2 and VEGF). …”
Get full text

Computational nanobody design through deep generative modeling and epitope landscape profiling by Liyun Huo, Tian Tian, Yanqin Xu, Qin Qin, Xinyi Jiang, Qiang Huang

“…The nanobody-enriched epitopes showed strong overlap with known functional regions, suggesting potential biological activity. …”
Get full text

Digital Platforms for the Built Environment: A Systematic Review Across Sectors and Scales by Michele Berlato, Leonardo Binni, Dilan Durmus, Chiara Gatto, Letizia Giusti, Alessia Massari, Beatrice Maria Toldo, Stefano Cascone, Claudio Mirarchi

“…Unlike existing reviews focused on single technologies or sectors, this work offers a cross-sectoral synthesis, highlighting shared challenges and opportunities across disciplines and lifecycle stages. It identifies the functional roles, enabling technologies and systemic barriers affecting digital platform adoption, such as fragmented data sources, limited interoperability between systems and siloed organizational processes. …”
Get full text

Design and Performance Optimization of a 3D-Printed SIW Antenna for Free-Space Applications by Md Mahabub Alam, Nurhafizah Abu Talip Yusof, Nurazyyati Inas, Muhammad Naim Aminuddin, Bifta Sama Bari, Yasmin Abdul Wahab, Mohamad Shaiful Abdul Karim

“…This paper presents the design and performance evaluation of a Substrate-Integrated Waveguide (SIW) antenna fabricated using 3D printing technology, with a focus on optimizing its performance for future free-space applications. …”
Get full text

Bioinspired hydrogel for sustained minocycline release: A superior periodontitis solution by Shiyao Liu, Wenqian Zheng, Lina Wang, Yajie Zhang, Kang Feng, Yan Zhang, Haitao Yang, Yao Xiao, Chenxi Sun, Xiqiang Liu, Baoyang Lu, Xuemin Yin

“…The sustained release of minocycline, combined with the hydrogel's acidic microenvironment and the antioxidant functional groups, provides M@PP with excellent biocompatibility, potent antibacterial activity (98.1 % against P. gingivalis), and enhanced anti-inflammatory properties. …”
Get full text

Evolution of cetacean-specific conserved non-coding elements suggests their role in the limb changes during secondary aquatic adaptation by Zhenhua Zhang, Zhenpeng Yu, Yujie Chong, Yao Liu, Jia Liu, Wenhua Ren, Shixia Xu, Guang Yang

“…Conclusions In summary, our study supports the functional role of CNE sequence divergence and the complex mechanisms underlying limb morphology changes in cetaceans.…”
Get full text

Spectrum Fitting Approach for Passive Wireless SAW Sensor Interrogation Using Software-Defined Radio by Shihao Wang, Qi Wang, Guopeng Zhu, Lei Liu, Xinning Cao, Tingxin Ren, Yue Zhou, Hao Jin

“…The feasibility of the proposed method is theoretically analyzed, and its performance under different window functions and length of fast Fourier transform (FFT) configurations is evaluated through simulations and experimental measurements. …”
Get full text

NO: a key player in microbiome dynamics and cancer pathogenesis by Seyedeh Kimia Jasemi, Seyedeh Kimia Jasemi, Hossein Faridafshar, Hossein Faridafshar, Hossein Faridafshar, Mohammed Namiq Amin, Mohammed Namiq Amin, Mehregan Babamohamadi, Mehregan Babamohamadi, Marjan Falahati, Marjan Falahati, Roshanak Amirian, Roshanak Amirian, Zhila Izadi, Zhila Izadi

“…This bioactive molecule benefits bodily functions like host defense and neuronal communication and improves vascular and metabolic health. …”
Get full text

Implementation of Sensor Input Setup Assistance Service Using Generative AI for <i>SEMAR</i> IoT Application Server Platform by I Nyoman Darma Kotama, Nobuo Funabiki, Yohanes Yohanie Fridelin Panduman, Komang Candra Brata, Anak Agung Surya Pradhana, Noprianto, I Gusti Made Ngurah Desnanjaya

“…It is equipped with rich functions for collecting, analyzing, and visualizing various data. …”
Get full text

NF-κB and apoptosis: colorectal cancer progression and novel strategies for treatment by Sina Sadati, Amirreza Khalaji, Ali Bonyad, Sara Khoshdooz, Kosar Sadat Hosseini Kolbadi, Ashkan Bahrami, Mohammad Saeid Moeinfar, Mohammadmatin Morshedi, Amireza Ghamsaraian, Majid Eterafi, Reza Eshraghi, Mahmood Khaksary Mahabady, Hamed Mirzaei

“…Abstract Colorectal cancer (CRC), the third most prevalent cancer worldwide, presents a significant burden in terms of both mortality and morbidity. …”
Get full text

Univariate deep learning framework for short-term SST forecasting at high spatio-temporal scales by Jagdish Prajapati, Balaji Baduru, Athul C R, Biswamoy Paul, Vinod Daiya, Arya Paul

“…We present a univariate hybrid machine learning framework to predict daily high resolution Sea Surface Temperature (SST) near the Gulf of Kutch region at a resolution of ∼5.5 km. …”
Get full text

Molecular cloning and expression characteristics of ghrl and ghsr genes in bighead carp (Hypophthalmichthys nobilis) by Pan Wang, Jianjun Fu, Mingkun Luo, Xiulan Shi, Wenbin Zhu, Lanmei Wang, Shichang Shu, Zaijie Dong

“…Ghrelin (ghrl) and its receptor gene ghsr (growth hormone secretagogue receptor) regulate numerous physiological functions, including growth hormone secretion and food intake. …”
Get full text

Characterization and expression analysis of transcription factors in Spartina alterniflora unveil their critical roles in salt stress resistance by Yuanyuan Jiang, Yuanyuan Jiang, Yuanyuan Jiang, Shoukun Chen, Shoukun Chen, Shoukun Chen, Shuqiang Gao, Shuqiang Gao, Shuqiang Gao, Jiahui Geng, Jiahui Geng, Qin Shu, Qin Shu, Shang Gao, Shang Gao, Huihui Li, Huihui Li

“…Spartina alterniflora, a halophytic species renowned for its exceptional salt resistance, provides an ideal model for investigating the regulatory mechanisms underlying salt tolerance.MethodsHere, we present a comprehensive genome-wide identification and characterization of TFs in S. alterniflora. …”
Get full text

Comparative Transcriptome Analysis Highlights the Role of <i>NlABCG14</i> in the Honeydew Production of Virulent Brown Planthoppers (<i>Nilaparvata lugens</i> Stål) to Resistant Ri... by Shengli Jing, Mengjia Geng, Bojie Lu, Bing Wu, Yuhan Shao, Chenxi Li, Qingqing Yu, Jingang Xu, Wei Hu, Qingsong Liu, Bin Yu

“…Via RNA sequencing, the present study identified distinct transcriptional profiles in avirulent (biotype 1) and virulent (biotype Y) BPH nymphs both before and after feeding on YHY15 rice. …”
Get full text