Computational Resources and Infrastructures for a Novel Bioinformatics Laboratory: A Case Study by Emanuel Maldonado, Manuel C. Lemos

“…The four novel designs offered substantial improvements when compared to the upgraded designs, additionally corroborated by performance evaluations, which resulted in an overall highest performance of the novel designs. Conclusions: We present work that was developed over two years until completion with functioning infrastructure. …”
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The viral and cellular microRNA targetome in lymphoblastoid cell lines. by Rebecca L Skalsky, David L Corcoran, Eva Gottwein, Christopher L Frank, Dong Kang, Markus Hafner, Jeffrey D Nusbaum, Regina Feederle, Henri-Jacques Delecluse, Micah A Luftig, Thomas Tuschl, Uwe Ohler, Bryan R Cullen

“…This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.…”
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Evading efficiency-voltage trade-off in magnesium-air batteries through solute atoms and second phases synergy by Hongxing Liang, Liang Wu, Chenchen Zhao, Chuantian Zhai, Wenbo Du

“…Furthermore, the activation of the second phase, introducing additional galvanic couples, significantly contributes to this performance. This study presents valuable insights that can guide the design of novel anodes, contributing to the advancement of high-performance magnesium-air batteries.…”
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Development of Experimental Setup to Investigate the Control System for Infusion Solutions Dosing Process by Fedir Matiko, Volodymyr Shaleva

“…The paper presents the results on developing an experimental setup for the research into the control system for the solution dosing process based on the weighing method of dosing. …”
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Anatomical variants of the posterior horns of the lateral ventricles: an MRI study by Ronen Spierer, Omer Zarrabi Itzhak, Jonathan Gross, Tamer Sobeh, Shai Shrot, Shai Shrot

“…IntroductionAnatomical variations in the posterior horns of the lateral ventricles are well-documented, with the horn presenting as open, constricted, or completely closed. …”
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High-Performance Hydroxyapatite Scaffold Combined with Selenium and Reduced Graphene Oxide for Bone Regeneration Applications by Y. Beygi-Khosrowshahi, S. Zakhireh

“…Scaffold biomaterials have profound regulatory effects on the functionality of mesenchymal stem cells (MSCs). In the present study, the three-component bioceramic of selenium/reduced graphene oxide/hydroxyapatite (Se/RGO/HA) was developed and its performance to repair bone defects was compared to that of HA. …”
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Multifactorial, biomarker-based model for assessing the state of patients with schizophrenia by E. G. Cheremnykh, O. K. Savushkina, T. A. Prokhorova, S. A. Zozulya, I. N. Otman, A. N. Pozdnyakova, N. S. Karpova, Yu. E. Shilov, T. P. Klyushnik

“…Objective comparison of biological markers and real clinical presentation is especially difficult in mental disorders, which are classified according to a large number of diagnostic criteria and a wide variety of symptoms. …”
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Psychosocial factors of psychological maladaptation in female patients of a cosmetology clinic by E. S. Bagnenko

“…In the field of aesthetic medicine, there is a lack of psychological research despite the obvious impact of cosmetic defects on the emotional state and social functioning of a person. Only a few studies indicate psychological maladaptation in patients of a cosmetology clinic, which is reflected in the frequency of the occurrence of anxiety, depression and personality disorders exceeding their levels in population. …”
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Combined metabolome and transcriptome analysis provides molecular insights into reproductive process in Chuanxiang Black and Landrace pigs by Jiangling Li, Jinling Zhang, Sujun Zhao, Qiushi Wang, Rui Liu, Xiaohui Chen, Zhiping He

“…Differential circRNA target gene enrichment analysis revealed 4,179 DEGs, including 3,022 genes involved in biological processes, 477 in cellular components, and 680 in molecular functions. Differential analysis of miRNA between the two groups revealed 2,512 DEGs, including 1,628 upregulated and 884 downregulated genes. …”
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Packaging with lower sperm concentrations improves post-thawing quality parameters of rooster semen by Esther Díaz Ruiz, Juan Vicente Delgado Bermejo, Francisco Javier Navas González, José Manuel León Jurado, Antonio González Ariza

“…Standardisation of the sperm cryopreservation technique in cockerels plays a key role, with sperm concentration being an important factor to determine. The present study aims to determine which sperm concentration provides the best post-thawing semen quality results. …”
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Brain-derived neurotrophic factor and neurotrophic tyrosine receptor kinase-2 in stallion testes: insights into seasonal changes and potential roles in spermatogenesis by Muhammad Shakeel, Minjung Yoon

“…Further investigation is necessary to explore the functional implications of BDNF signaling on spermatogenesis, focusing on the regulatory mechanisms that govern the seasonal expression patterns observed. …”
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The place of tadalafil in the treatment of PAH in the light of new clinical guidelines of the Eurasian Association of Cardiologists by T. V. Martynyuk

“…Tadacardil is indicated for use in adult patients with PAH functional class II and III according to the WHO classification to increase exercise tolerance. …”
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Attempts to Use Thermal Imaging to Assess the Microbiological Safety of Poultry Meat in Modified Atmosphere Packaging by Edyta Lipińska, Katarzyna Pobiega, Kamil Piwowarek, Piotr Koczoń, Stanisław Błażejak

“…This study found that the number of microorganisms increased between the 2nd and 10th days of storage for the poultry meat samples of four log CFU/g, leading to a temperature increase of 2.61 °C, and also, the intensities and frequencies of selected IR bands generated by vibrations of various groups of atoms changed, including functional groups present in the compounds contained in the tested samples. …”
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Comparison of dCas9-activator complexes for the activation of PDX1 and NGN3 pancreatic genes using the CRISPR system by Ersin Akıncı, Mehmet Fatih Cengiz, Fatma Akçakale Kaba, Adem Kaba

“…Future studies should explore the long-term functionality and stability of these β-like cells in preclinical models to further assess their therapeutic potential. …”
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RootTracer: An intuitive solution for root image annotation by Maichol Dadi, Annalisa Franco, Giuseppe Sangiorgi, Silvio Salvi, Alessandra Lumini

“…In this study, we introduce “RootTracer” a software tool that offers a variety of functionalities. RootTracer enables users to quickly and easily create RSML files that capture the structure of a root system by inputting the image to be analyzed and marking or modifying key points within the image. …”
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Experimental generation of SNP haplotype signatures in patients with sickle cell anaemia. by Stephan Menzel, Jian Qin, Nisha Vasavda, Swee Lay Thein, Ramesh Ramakrishnan

“…Procedures such as the one described here would therefore benefit genetic mapping and functional studies as well as diagnostic procedures where the identity or parental origin of short genetic fragments is of importance.…”
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Immune Reactivity to Raw and Processed Foods and Their Possible Contributions to Autoimmunity by Aristo Vojdani, Elroy Vojdani, Carina Benzvi, Aaron Lerner

“…In a healthy person with a normal functioning immune system, food substances encounter no resistance and are allowed passage through the immune barriers without triggering immune reactivity. …”
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Copy number variation of KIR genes influences HIV-1 control. by Kimberly Pelak, Anna C Need, Jacques Fellay, Kevin V Shianna, Sheng Feng, Thomas J Urban, Dongliang Ge, Andrea De Luca, Javier Martinez-Picado, Steven M Wolinsky, Jeremy J Martinson, Beth D Jamieson, Jay H Bream, Maureen P Martin, Persephone Borrow, Norman L Letvin, Andrew J McMichael, Barton F Haynes, Amalio Telenti, Mary Carrington, David B Goldstein, Galit Alter, NIAID Center for HIV/AIDS Vaccine Immunology

“…We further provide functional data that demonstrate that NK cells from individuals with multiple copies of KIR3DL1, in the presence of KIR3DS1 and the appropriate ligands, inhibit HIV-1 replication more robustly, and associated with a significant expansion in the frequency of KIR3DS1+, but not KIR3DL1+, NK cells in their peripheral blood. …”
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The visuomotor synchronization immersive virtual reality of a depression avatar in a stigma context experience mobilizes the fronto-parietal cortex and anterior insula by Kelssy Hitomi dos Santos Kawata, Kelssy Hitomi dos Santos Kawata, Wey Guan Lem, Koki Ono, Hiroshi Oyama

“…A significant negative effect of the SoE score was identified in the frontoparietal and anterior insula only for the visuomotor synchronization IVR experience of guiding the virtual right hand of the avatar with depression, implicating interoceptive and multisensory integration.DiscussionWe demonstrated that all five subcomponents of the SoE were present, and that decreased activity in the frontoparietal and anterior insula were crucial brain regions for the virtual human body to be perceived as one’s own body and promote conscious feelings of embodiment.…”
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Unlocking the antioxidant and antibacterial potential of exopolysaccharides produced by endophytic fungi (Aspergillus fumigatus and Preussia isabellae) isolated from Tanzania’s man... by Bhoke Marwa Nyaisaba, Rose Justus Masalu, Hawa Myovela, Cyprian Beda Mpinda

“…Fourier transform infrared spectra revealed varying degrees of functional groups associated with polysaccharides, thereby verifying the presence of EPS. …”
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