Modulation of Digestive Enzyme Activities and Intestinal γ-Proteobacteria in Gilthead Sea Bream Fed High-Fat Diets Supplemented with HIDROX^® Olive Oil Extract by Irene García-Meilán, Sara Balbuena-Pecino, Manel Montblanch, Sara Ramos-Romero, Ramón Fontanillas, Joaquim Gutiérrez, Encarnación Capilla, Isabel Navarro, Ángeles Gallardo

“…These problems can be assessed in two ways: by developing functional diets or using food restriction, which leads to compensatory growth. …”
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Patient-derived tumor explant models of tumor immune microenvironment reveal distinct and reproducible immunotherapy responses by Rita Turpin, Karita Peltonen, Jenna H. Rannikko, Ruixian Liu, Anita N. Kumari, Daniel Nicorici, Moon Hee Lee, Minna Mutka, Panu E. Kovanen, Laura Niinikoski, Tuomo Meretoja, Johanna Mattson, Petrus Järvinen, Kanerva Lahdensuo, Riikka Järvinen, Sara Tornberg, Tuomas Mirtti, Pia Boström, Ilkka Koskivuo, Anil Thotakura, Jeroen Pouwels, Maija Hollmén, Satu Mustjoki, Juha Klefström

“…Tumor-resident immune cells play a crucial role in eliciting anti-tumor immunity and immunomodulatory drug responses, yet these functions have been difficult to study without tractable models of the tumor immune microenvironment (TIME). …”
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Altered oral health and microbiota in drug-free patients with schizophrenia by Huawei Huang, Naiyan Yang, Mian-mian Chen, Xiaoting Chen, Wei Chen, Xiaoping Li, Yuchun Chen, Zhengang Deng, Wenbing Zhou, Shu-xian Xu, Xin-hui Xie

“…The differential taxa and microbial functions showed a strong correlation with clinical oral conditions. …”
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Advances in Novel Diagnostic Techniques for Alveolar Echinococcosis by Huanhuan Liu, Yijia Xie, Xiaoyu An, Dazhuang Xu, Shundong Cai, Chengchao Chu, Gang Liu

“…Alveolar echinococcosis (AE), caused by the larval stage of the tapeworm <i>Echinococcus multilocularis</i>, is a serious parasitic disease that presents significant health risks and challenges for both patients and healthcare systems. …”
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Tropical fruit‐derived starch: An innovative strategy for high‐value nutritional processing of agricultural solid waste by Tian Lan, Jiaqi Wang, Yongwu Li, Yaguo Wang, Xiangyu Sun, Yulin Fang, Tingting Ma

“…Moreover, tropical fruit‐derived starch retains the rich nutrients and functional components present in fruits to some extent, thereby offering potential health benefits and greater consumer acceptance. …”
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NKD1 enhances colon cancer progression by inhibiting the autophagic degradation of MYC by Wenbin Lu, Jianjun Tang, Yue Wang, Xiaoyan Gu, Hua Zhang, Yungang Liu, Ying Xiao, Qi Zhu, Jianzhong Deng, Ying Shen, Anqi Jiang, Yixin Xu, Jianhua Jin, Yongzhong Hou, Qian Liu

“…Moreover, NKD1 activated the expression of MYC downstream target genes through MYC. Functionally, the PPARδ/NKD1/MYC signaling pathway increased colon cancer cells’ proliferation, migration and angiogenesis capabilities. …”
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Targeted codelivery of nitric oxide and hydrogen sulfide for enhanced antithrombosis efficacy by Weiliang Deng, Zhixin Xu, Tong Hua, Guangbo Ji, Zihang Wang, Pei Liu, Yupeng Zhang, Shuo Li, Yuqiu Chao, Meng Qian, Qiang Zhao, Jinwei Tian

“…As important gaseous signaling molecules, both nitric oxide (NO) and hydrogen sulfide (H2S) demonstrate antiplatelet and anticoagulant functions, but little attention has been given to their synergistic effect and the underlying mechanism. …”
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Quantification of the biological control of aphids by their natural enemies in sugar beet crops by Lena Barascou, Marianne Doehler, Ségolène Buzy, Aurore Arnoult, Eloi Salembier, Valentin Richard, Loïc Daniel, Frank Duval, Anne Le Ralec

“…However, the relative contribution of these different functional groups of natural enemies to aphid regulation is poorly known in major crop-pest systems. …”
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Scaffold-Free Strategies in Dental Pulp/Dentine Tissue Engineering: Current Status and Implications for Regenerative Biological Processes by Mohammad Samiei, Martin Conrad Harmsen, Elaheh Dalir Abdolahinia, Jaleh Barar, Xenos Petridis

“…The ultimate goal of regenerative endodontics is to restore dental pulp tissue with structural organization and functional characteristics akin to the native pulp, leveraging advancements in tissue engineering and biomaterial sciences. …”
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Inhibition of retinal neovascularization by Dendrobium polysaccharides: a review by Dan Liu, Dan Liu, Dan Liu, Dan Liu, Xingwang Chen, Xingwang Chen, Xingwang Chen, Xingwang Chen, Shanjun Cai, Shanjun Cai, Shanjun Cai, Shanjun Cai

“…This review systematically summarizes the structural and functional properties of DP, explores their mechanism of action and experimental evidence in retinal neovascularization, and analyzes their potential as a new therapeutic strategy for retinal diseases. …”
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Comparison of Cytotoxicity and Antioxidant, Antibacterial, and Anti-Inflammatory Activity of Aqueous and Ethanolic Extracts from <i>Malus domestica</i>, <i>Prunus armeniaca</i>, an... by Martyna Zagórska-Dziok, Aleksandra Ziemlewska, Magdalena Wójciak, Ireneusz Sowa, Ewa Wąsik-Szczepanek, Zofia Nizioł-Łukaszewska

“…This study presents a comprehensive evaluation of the biological properties of aqueous and aqueous–ethanolic leaf extracts from <i>Malus domestica</i>, <i>Prunus armeniaca</i>, and <i>Prunus cerasus</i>, which are plant waste materials. …”
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Specific features of designing a database for neuro-oncological 3D MRI images to be used in training artificial intelligence by E. V. Amelina, A. Yu. Letyagin, B. N. Tuchinov, N. Yu. Tolstokulakov, M. E. Amelin, E. N. Pavlovsky, V. V. Groza, S. K. Golushko

“…The database was used to create artificial intelligence systems with the “physician assistant” functions for preoperative MRI diagnostics in neurosurgery.…”
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Primary failure of eruption: From molecular diagnosis to therapeutic management by Delphine Wagner, Tristan Rey, Marie-Cécile Maniere, Sarah Dubourg, Agnès Bloch-Zupan, Marion Strub

“…Results: The clinical phenotype (type and number of involved teeth, depth of bone inclusions, functional consequences) is variable within the family. …”
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DFT insights into the structural, mechanical, electronic, optical, and thermal properties of Cr2AC (A = Si, Al, Ga, Ge, and P) MAX phases carbides by Md. Nurul Amin, Abdulla Al Faysal, Ahmed Azzouz-Rached, Faisal Islam Chowdhury, Jamal Uddin, Join Uddin, Jahidul Islam, Ali Reza Piyal, Anjan Kumar Chowdhury, A. K. M. Rezaur Rahman

“…This work examines the structural, electronic, mechanical, optical, and thermal properties of Cr2AC (A = Si, Al, Ga, Ge, and P) MAX phases using density functional theory. These properties are investigated through first-principles calculations within the generalized gradient approximation using the CASTEP software package. …”
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Stability-Guided Formulation of a Light-Sensitive D-LSD Capsule for Clinical Investigation by Bernard Do, Luc Mallet, Maxime Annereau, Danielle Libong, Audrey Solgadi, Florence Vorspan, Muriel Paul, Philippe-Henri Secretan

“…However, the extreme light sensitivity of D-LSD presents a significant challenge in developing suitable pharmaceutical forms, particularly for clinical trial settings. …”
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Mesenchymal Stem Cell Therapy Using Human Umbilical Cord in a Rat Model of Autoimmune-Induced Premature Ovarian Failure by Zhe Wang, Quanwei Wei, Hao Wang, Linxiao Han, Hongjian Dai, Xiaoxin Qian, Hongliang Yu, Manqun Yin, Fangxiong Shi, Nianmin Qi

“…In this study, different concentrations of UCMSCs were injected into induced POF rats. Ovarian functions were examined by evaluating the estrus cycle, follicular morphology, hormonal secretion, and the proliferation and apoptosis of granulosa cells. …”
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Transcript-activated collagen matrix for enhanced bone marrow stem cell differentiation and osteochondral repair by Gang Zhong, Yixuan Luo, Meng Wang, Zhengran Yu, Xuenong Zou, Gang Wang, Fei Chen, Yin Yu

“…Traditional approaches, such as autologous chondrocyte implantation (ACI) and matrix-induced autologous chondrocyte implantation (MACI), have shown promise but are limited by issues like insufficient cell availability, dedifferentiation of chondrocytes during expansion, and the formation of fibrocartilage rather than functional hyaline cartilage. This study presents a promising approach utilizing transcript-activated matrices (TAMs) with mRNA to enhance the therapeutic potential of bone marrow mesenchymal stem cells (BMSCs) in situ. …”
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CLSY docking to Pol IV requires a conserved domain critical for small RNA biogenesis and transposon silencing by Luisa Felgines, Bart Rymen, Laura M. Martins, Guanghui Xu, Calvin Matteoli, Christophe Himber, Ming Zhou, Josh Eis, Ceyda Coruh, Marcel Böhrer, Lauriane Kuhn, Johana Chicher, Vijaya Pandey, Philippe Hammann, James Wohlschlegel, Florent Waltz, Julie A. Law, Todd Blevins

“…Together, these findings provide structural and functional insights into a critical protein feature that distinguishes Pol IV from other RNA polymerases, allowing it to promote genome stability by targeting TEs for silencing.…”
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Relationships Between Immune‐Inflammatory Features and Social Cognitive Impairments in Patients With Schizophrenia Spectrum Disorders: A Systematic Review by Alexandre Carpentier, Dimitrios Zampetas, Alexandre Durand, Mickael Naassila, Marie‐Cécile Bralet

“…These impairments appear from early life and are associated with poor functional and social prognosis. The origin of these impairments is not fully understood. …”
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Addendum to How Small Can S-boxes Be? by Yu Sun, Lixuan Wu, Chenhao Jia, Tingting Cui, Kai Hu, Meiqin Wang

“… In ToSC 2025(1), Jia et al. proposed an SAT-aided automatic search tool for the S-box design. A part of the functionality of this tool is to search for implementations of an S-box with good area and gate-depth complexity. …”
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