Extracellular vesicles derived from mature dendritic cells loaded with cDC1-specific chemokine XCL1 combined with chemotherapy-induced ICD for the treatment of castration-resistant... by Zhongqiang Fan, Zhao Wang, Hui Zhang, Hao Zhang, Rui Zhao, Shimiao Zhu, Xiaoqiang Liu

“…The aim of this study was to evaluate the antitumor efficacy of a functional DCs-derived extracellular vesicles in castration-resistant prostate cancer. …”
Get full text

Les quais nos 1, 12 et 13 du port romain de Saint-Lupien à Rezé/Ratiatum (Loire-Atlantique) by Xavier Favreau, Nicolas Ménez

“…This tiering of monumental port terraces, which developed, operated and was modified, only functioned for about a century. Initiated in the first half of the 3rd c. …”
Get full text

Relationship of immunogenetic and immunologic markers and their influence on disease activity and radiological progression in patients with early rheumatoid arthritis by N V Demidova

“…Activity of RA was assessed with DAS28 and functional status – with Russian version of HAQ questionnaire. …”
Get full text

Enhancing CAR T‐cell therapy manufacturing efficiency through semi‐automated bioprocessing by Jason Isaacson, Prajakta Bhanap, Nicholas Putnam, Jasmine Padilla, Nujhat Fatima, Max Dotson, Danny Hayoun, Moloud Ahmadi, Gertrude Nonterah, Yongchang Ji

“…Results The results demonstrated the successful generation of functional CAR T cells using a semi‐automated instrument workflow. …”
Get full text

Genomic insights into a novel ST17306 Escherichia coli Isolate carrying tet(X4) from an infant with bronchopneumonia in China by Mengting Luo, Qiao Li, Fang He, Zhengquan Yang

“…Methods: The complete genome of E. coli Q65 was sequenced using a combination of Illumina NovaSeq 6000 and Oxford Nanopore MinION sequencing platforms. Functional annotation was conducted using the NCBI Prokaryotic Genome Annotation Pipeline (PGAP), and genomic features were further analyzed with a range of bioinformatics tools. …”
Get full text

Predictors of Intensive Care Unit Admission in Red Code Patients in the Emergency Department: A Single-Center Retrospective Observational Study by Erkan Boğa

“… Background: Red code patients in the emergency department require urgent medicalcare because they present with life-threatening medical conditions. …”
Get full text

Study protocol for an internahaational prospective non-randomised trial evaluating the long-term outcomes of transcatheter aortic valve implantation versus surgical aortic valve re... by Antonio Salsano, Francesco Nappi, Cristiano Spadaccio, Antonio Fiore, Zein El-Dean, Camille Bourgois, Antonio Nenna, Thibaut Schoell

“…The principal clinical outcome under consideration will be the composite degree of all-cause mortality, ischaemic stroke or rehospitalisation at 10 years. The present study will also have a number of secondary endpoints, including all-cause mortality, followed by functional status, hospitalisation, neurocognition, physiological measures (echocardiographic assessment), adverse events and reoperation.Ethics and dissemination It is hypothesised that the nature of the trials will serve to minimise bias related to institutional volume and surgical experience. …”
Get full text

Gelatin/PLA-loaded gold nanocomposites synthesis using Syzygium cumini fruit extract and their antioxidant, antibacterial, anti-inflammatory, antidiabetic and anti-Alzheimer’s acti... by Manickam Rajkumar, S. I. Davis Presley, Nathiya Thiyagarajulu, Koyeli Girigoswami, Gopalarethinam Janani, Chinnaperumal Kamaraj, Bharathi Madheswaran, Bhupendra Prajapati, Nemat Ali, Mohammad Rashid Khan

“…The FTIR spectrum showed various functional groups and the XRD patterns confirmed the crystalline shape and structure of nanocomposites. …”
Get full text

Developmental trajectories of balance performance in preschoolers: age and gender differences for 3–6 years old Chinese children by Ruiyuan Li, Jiefeng Zhu, Ruiqin Li, Xiaoting Wang, Taishan Tian, Bingjun Wan

“…Therefore, the purpose of the present study was to assess balance development in a multidimensional way in preschool children and to examine the effect of age and gender on preschool children’s balance performance.MethodsA total of 619 children (296 boys and 323 girls; aged 3–6 years) from China participated in the present study. …”
Get full text

Max Ernst et Marguerite Duras. Peintre et écrivain de l'exil ? by Fatima SEDDAOUI

“…This article examines the importance and functions of exile in the work of Max Ernst and Marguerite Duras. …”
Get full text

THE PLACE OF PROFESSIONAL EDUCATION SYSTEM IN FORMATION OF GRADUATES’ COMPETITIVENESS by G. F. Shafranov-Kutsev, G. Z. Efimova

“…Moreover, the outcomes of the present research can be useful for the heads and administrators of organisations and enterprises, who are engaged in successful professional adaptation of young employees.…”
Get full text

MANAGING SUSTAINABLE TOURISM OF PERAWAN BEACH, EAST JAVA, INDONESIA BASED ON THE COASTAL ECOSYSTEM SERVICE (CES) APPROACH by Adellia Wardatus SHOLEHA, Sumarmi SUMARMI

“…Coastal tourism at Perawan Beach in Malang Regency, East Java, presents both opportunities and sustainability challenge. …”
Get full text

Chemical compounds, FTIR and <i>in vitro</i> antibacterial analyses of the acetone stem bark extract of <i>Ziziphus mucronata</i> subsp. <i>mucronata</i> (Buffalo Thorn) against po... by Morenike Olutumbi Adeoye-Isijola, Aderonke Ariyike Olajuyigbe, Kehinde Oluwakemi Fagbemi, Kubendran Kista Naidoo, Roger Murugas Coopoosamy, Olufunmiso Olusola Olajuyigbe

“…Fourier transform infrared (FTIR) spectroscopy was used to determine the functional groups of the chemical compounds in the plant extract. …”
Get full text

Prediction of Flexural Ultimate Capacity for Reinforced UHPC Beams Using Ensemble Learning and SHAP Method by Zhe Zhang, Xuemei Zhou, Ping Zhu, Zhaochao Li, Yichuan Wang

“…The optimal model functionality may be accomplished by properly considering the effects of database subset distribution on the performance prediction and model stability. …”
Get full text

Evaluation Methods for the Human–Land Coupling Coordination Relationship in a Metro Station Area: A Case Study of Chengdu Metro Line 1 by Zhiyue Qiu, Shirui Wen, Hong Yuan, Ziyi Liu, Yao Wei, Siqi Yanling, Runlong Dai, Xiang Li, Yuxin Gu

“…At present, more than 200 cities in the world have developed metro systems. …”
Get full text

A thioacetamide-induced hepatic encephalopathy model in C57BL/6 mice: a behavioral and neurochemical study Modelo de encefalopatia hepática induzida por tioacetamida em camundongos... by Aline Silva de Miranda, David Henrique Rodrigues, Luciene Bruno Vieira, Cristiano Xavier Lima, Milene Alvarenga Rachid, Paula Vieira Teixeira Vidigal, Marcus Vinicius Gomez, Helton José dos Reis, Cristina Guatimosim, Antônio Lúcio Teixeira

“…RESULTS: The neuropsychiatric state, motor behavior and reflex and sensory functions were significantly altered in the group receiving 600 mg/kg of TAA. …”
Get full text

Fatty acid metabolism shapes immune responses in chronic lymphocytic leukemia by Yang Zhang, Jun Ma, Peipei Li, Kang Lu, Yang Han, Xinting Hu, Xiaosheng Fang, Xin Wang, Ya Zhang

“…Single-cell RNA sequencing was used to analyze the expression of key FAM genes in CLL immune cell subsets and investigate cellular communication. Functional assays, including cell viability, drug sensitivity, and oxygen consumption assays, were performed to assess the impact of fatty acid oxidation (FAO) inhibition on CLL cells. …”
Get full text

Impact of pH-Responsive Cisplatin/Ribavirin-Loaded Monodispersed Magnetic Silica Nanocomposite on A549 Lung Cancer Cells by Dana Almohazey, Vijaya Ravinayagam, Hatim Dafalla, Rabindran Jermy Balasamy

“…<b>Background/Objectives</b>: Nanocarrier particle design for treating chronic pulmonary diseases presents several challenges, including anatomical and physiological barriers. …”
Get full text

Decellularized porcine liver scaffold for maintaining the viability and capacity of pancreatic islets by N. V. Baranova, A. S. Ponomareva, A. D. Belova, L. A. Kirsanova, D. D. Filin, E. A. Nemets, Yu. B. Basok, V. I. Sevastianov

“…Bioengineered pancreatic constructs based on scaffolds made from decellularized tissues and pancreatic islets (PIs) may be used to extend the functional activity of transplanted PIs in patients with type I diabetes. …”
Get full text

Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment by Ziqin Wei, Ziqin Wei, Hongfang Mu, Fangfang Qiu, Fangfang Qiu, Minghui Zhao, Minghui Zhao, Xiaojing Zhang, Wenbin Li, Hai Jia, Rong Wang, Rong Wang

“…Rhodamine 123 accumulation assay showed that SAHA could enhance ABCB1 functional activity by inducing its expression. After HDAC5 was knocked down using siRNA, ABCB1 and H3K9ac expression increased, and ABCB1 functional activity was enhanced. …”
Get full text