Psilocybin’s acute and persistent brain effects: a precision imaging drug trial by Subha Subramanian, Travis Rick Reneau, Demetrius Perry, Ravi Chacko, Timothy O. Laumann, Karin Flavin, Christine Horan, Julie Schweiger, Nicholas Metcalf, Eric J. Lenze, Abraham Z. Snyder, Nico U. F. Dosenbach, Ginger Nicol, Joshua S. Siegel

“…Abstract Psilocybin (PSIL) is a psychedelic drug and a promising experimental therapeutic for many psychiatric conditions. Precision functional mapping (PFM) combines densely repeated resting state fMRI sampling and individual-specific network mapping to improve signal-to-noise ratio (SNR) and effect size in brain imaging research. …”
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Exploring salinity induced adaptations in marine diatoms using advanced photonic techniques by Julijana Cvjetinovic, Yekaterina D. Bedoshvili, Nickolai A. Davidovich, Eugene G. Maksimov, Ekaterina S. Prikhozhdenko, Daria A. Todorenko, Daria V. Bodunova, Olga I. Davidovich, Igor S. Sergeev, Dmitry A. Gorin

“…The study of diatoms using advanced photonic methods remains a relatively underexplored area, presenting significant opportunities for pioneering discoveries. …”
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Neuroinflammatory Markers in the Serum of Prepubertal Children with Down Syndrome by Luigi Tarani, Valentina Carito, Giampiero Ferraguti, Carla Petrella, Antonio Greco, Massimo Ralli, Marisa Patrizia Messina, Debora Rasio, Enrica De Luca, Carolina Putotto, Paolo Versacci, Mauro Ceccanti, Marco Fiore

“…Although DS individuals are mostly perceived as characterized by some distinct physical features, cognitive disabilities, and cardiac defects, they also show important dysregulations of immune functions. While critical information is available for adults with DS, little literature is available on the neuroinflammation in prepubertal DS children. …”
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Management of the Vertical Dimension in the Camouflage Treatment of an Adult Skeletal Class III Malocclusion by Manuel Gustavo Chávez Sevillano, Gina Judith Flores Diaz, Luciane Macedo de Menezes, Livia Kelly Ferraz Nunes, José Augusto Mendes Miguel, Cátia Cardoso Abdo Quintão

“…At the end of the orthodontic treatment, it was possible to observe an improved facial profile, a nice smile, and a functional occlusion. The results remained stable at a three-year follow-up. …”
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Programmed polymeric integration of gold nanoparticles into multi-material 3D printed hydrogels by Said El Turk, Dileep Chekkaramkodi, Murad Ali, Abdulrahim A. Sajini, Haider Butt

“…We demonstrate selective functionalization (with plasmonic Au NPs) of targeted regions on several centimeter-scaled 3D-printed geometries. …”
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Green synthesis of agro-waste–derived potassium-doped graphene oxide for antimicrobial activity by Kamal Garwal, Chetna Tewari, Tanuja Arya, Jyoti Rawat, Veena Pande, Souvik Basak, Mayukh Bose, Yong Chae Jung, Nanda Gopal Sahoo

“…Herein we present a one-step synthesis of K-GO using Quercus ilex (oak fruit) as a sustainable precursor. …”
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Broadly neutralizing antibodies isolated from HEV convalescents confer protective effects in human liver-chimeric mice by George Ssebyatika, Katja Dinkelborg, Luisa J. Ströh, Florian Hinte, Laura Corneillie, Lucas Hueffner, Elina M. Guzman, Prossie L. Nankya, Nina Plückebaum, Lukas Fehlau, Jonathan Garn, Nele Meyer, Sarah Prallet, Ann-Kathrin Mehnert, Anke R. M. Kraft, Lieven Verhoye, Carina Jacobsen, Eike Steinmann, Heiner Wedemeyer, Abel Viejo-Borbolla, Viet Loan Dao Thi, Thomas Pietschmann, Marc Lütgehetmann, Philip Meuleman, Maura Dandri, Thomas Krey, Patrick Behrendt

“…Here, we report combined functional, biochemical, and X-ray crystallographic studies that characterize the human antibody response in convalescent HEV patients. …”
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Impact of high-fructose diet and metformin on histomorphological and molecular parameters of reproductive organs and vaginal microbiota of female rat by Mürşide Ayşe Demirel, Esra Şumlu, İbrahim Hanifi Özercan, Kazım Şahin, Mehmet Tuzcu, Veysel Bay, Öznur Ece Durmaz Kurşun, Mecit Orhan Uludağ, Fatma Akar

“…Although metformin has some functional effects on female fertility, its reproductive outcome on high fructose diet-induced metabolic syndrome is unclear. …”
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Advancing Enzyme-Based Detoxification Prediction with ToxZyme: An Ensemble Machine Learning Approach by Kashif Iqbal Sahibzada, Shumaila Shahid, Mohsina Akhter, Muhammad Faisal, Reham A. Abd El Rahman, Muhammad Imran, Yangyong Lv, Dongqing Wei, Yuansen Hu

“…The aaccurate prediction of enzymes with environment detoxification functions is crucial, not only to achieve a better understanding of bioremediation strategies, but also to alleviate environmental pollution. …”
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Slip-actuated bionic tactile sensing system with dynamic DC generator integrated E-textile for dexterous robotic manipulation by Vashin Gautham, Ashutosh Panpalia, Hamid Manouchehri, Krushang Khimjibhai Gabani, Vinoop Anil, Shakunthala Yerneni, Rohit Thakar, Aayush Nayyar, Mandar Anil Payare, Emily Jorgensen, Ruizhe Yang, Ehsan Esfahani, Jun Liu

“…This self-powered bionic tactile sensing system operates in conjunction with a normal force sensor, paralleling the functions of human rapid-adapting and slow-adapting mechanoreceptors, respectively. …”
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Neurokinin-1 receptors in the nucleus accumbens shell influence sensitivity to social defeat stress and stress-induced alcohol consumption in male mice by Matthew G. Solomon, Sadie E. Nennig, Mallory R. Cotton, Kimberly E. Whiting, Hannah D. Fulenwider, Jesse R. Schank

“…The NK1R is the endogenous receptor for the neuropeptide substance P (SP) and plays a prominent role in stress, anxiety, and addiction. In the present study, we assessed changes in NK1R protein levels in the NAC shell and implemented viral vector strategies to demonstrate a functional role of the NK1R in sensitivity to SDS. …”
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High-Performance stacking ensemble learning for thermoelectric figure-of-merit prediction by Yuelin Wang, Chengquan Zhong, Jingzi Zhang, Honghao Yao, Junjie Chen, Xi Lin

“…The model identifies 43 potential high-zT materials, including Pb0.97K0.03Te0.65S0.25Se0.1 with a predicted zT of 1.9. Density functional theory calculations confirm the superior electrical properties of this compound. …”
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Hepatic and Renal Toxicity Induced by TiO2 Nanoparticles in Rats: A Morphological and Metabonomic Study by Xavier Valentini, Pascaline Rugira, Annica Frau, Vanessa Tagliatti, Raphaël Conotte, Sophie Laurent, Jean-Marie Colet, Denis Nonclercq

“…Enzymatic markers of liver and kidney functions (such as AST and uric acid) are also disrupted only in animals exposed to highest doses. …”
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In vivo self-renewal and expansion of quiescent stem cells from a non-human primate by Jengmin Kang, Abhijnya Kanugovi, M. Pilar J. Stella, Zofija Frimand, Jean Farup, Andoni Urtasun, Shixuan Liu, Anne-Sofie Clausen, Heather Ishak, Summer Bui, Soochi Kim, Camille Ezran, Olga Botvinnik, Ermelinda Porpiglia, Mark A. Krasnow, Antoine de Morree, Thomas A. Rando

“…Finally, we note that our approach presents as a generalizable pipeline for the identification, isolation, and characterization of stem cell populations in new animal models.…”
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C-28 linker length modulates the activity of second-generation HIV-1 maturation inhibitors by Yuvraj KC, Aradhana Singh, Sayantani Datta, Ritika Das, Pranjal Raj Saxena, Subash Chapagain, T. J. Nitz, Carl Wild, Ritu Gaur

“…Our data has provided vital information that in addition to the nature of the functional group at C28 position of the MI, the length of linker contributes significantly to its activity. …”
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Synthetically Assisted Conservation and the Application of Emerging Biological Technologies for the Protection of Biodiversity by Jedediah F. Brodie, Amanda Emmel, Blake Wiedenheft, Ronald L. Sandler, Kent H. Redford, Courtney A. Schultz, Axel Moehrenschlager, Melanie Mark‐Shadbolt, W. Sebastian Kamau, Jennifer E. Helm, William A. C. Gendron, Summer L. Dunn, Michael K. Schwartz

“…ABSTRACT New tools of synthetic biology that enable precise manipulation of genomes, metabolic pathways, and ecosystems present new opportunities, risks, ethical dilemmas, and responsibilities for stewards of biodiversity. …”
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Advances in humanoid organoid-based research on inter-organ communications during cardiac organogenesis and cardiovascular diseases by Baoqiang Ni, Lingqun Ye, Yan Zhang, Shijun Hu, Wei Lei

“…This review focuses on the advancements and challenges of hiPSC-derived humanoid organoids in studying interactions between the heart and other organs, presenting a comprehensive exploration of this cutting-edge approach in systemic disease research.…”
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Critical Role of Skin in Pathogenesis: Bidirectional Crosstalk Between Skin and Multiple Organs by Wende Deng, Junyi Liu, Changheng Tang, Zhenghao Li, Ying Qiu, Han Zhou, Lanxuan Yang, Ting Li

“…ABSTRACT The skin, the largest organ in the human body, serves both as a mechanical barrier and an autonomous lymphoid organ, protecting against various environmental threats while maintaining the balance and functionality of multiple bodily systems. This relationship extends beyond the skin itself, involving other organs closely linked to skin homeostasis and related diseases. …”
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The Role of Botulinum Toxin for Masseter Muscle Hypertrophy: A Comprehensive Review by Martina Ferrillo, Eleonora Sommadossi, Loredana Raciti, Dario Calafiore, Kamal Mezian, Valeria Tarantino, Michele Vecchio, Umile Giuseppe Longo, Luigi Losco, Alessandro de Sire

“…Moreover, MMH may also have significant functional repercussions, including pain in the masseter region, often associated with temporomandibular disorders, fatigue, and discomfort during mastication. …”
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Mechanical and metrological characterisation of 17-4PH stainless steel structures processed by material extrusion additive manufacturing by Ana Romero, Miguel A. Caminero, Eustaquio García-Plaza, Pedro J. Núñez, Jesús M. Chacón, Gloria P. Rodríguez, Antonio Cañadilla, Juan L. Martínez

“…Additive manufacturing (AM) has progressed from its initial use in prototyping to the fabrication of fully functional components. However, the performance characteristics of parts produced by these techniques are still under investigation. …”
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