PI Kinase-EhGEF2-EhRho5 axis contributes to LPA stimulated macropinocytosis in Entamoeba histolytica. by Achala Apte, Maria Manich, Elisabeth Labruyère, Sunando Datta

“…In the current study, using site directed mutagenesis and RNAi based silencing, coupled with functional studies, we have demonstrated the involvement of EhRho5 in constitutive and LPA stimulated macropinocytosis. …”
Get full text

Formula and Technology Development for Obtaining Biologically Active Natural Food Additives by Smirnov S., Fazullina O.

“…The research featured the development of formulae and technologies for the production of biologically active additives (BAA) for functional foods with potential adaptogenic, antioxidant, and hepatoprotective properties. …”
Get full text

Protein dynamic communities from elastic network models align closely to the communities defined by molecular dynamics. by Sambit Kumar Mishra, Robert L Jernigan

“…These can correspond to structural domains, but are usually smaller parts that move with respect to one another in a protein's internal motions, key to its functional dynamics. Previous studies emphasized their importance to understand the nature of ligand-induced allosteric regulation. …”
Get full text

Network modeling of the intellectual competence structure by Yana I. Sipovskaya

“…This suggests that the intellectual competence construct is heterogeneous, reflecting differences in the functional roles and cognitive complexity of its components. …”
Get full text

Fc glycan sialylation of biotherapeutic monoclonal antibodies has limited impact on antibody‐dependent cellular cytotoxicity by Elaine Branstetter, Robert J. Duff, Scott Kuhns, Rupa Padaki

“…Different glycosylation patterns can affect Fc‐dependent activities, such as the ability of mAbs to bind Fcγ receptors on the effector cell surface, which is critical to immune effector functions, such as antibody‐dependent cellular cytotoxicity (ADCC). …”
Get full text

Banking ecosystems and marketplaces: digitalization trends by L. V. Prigoda, M. V. Alikaeva, Z. Cekerevac

“…The necessity of using an integrated approach in developing the rules for the functioning of financial ecosystems in the formation of an adequate development strategy, which will ensure the creation of a fair competitive environment in the financial market, has been substantiated. …”
Get full text

Identifying the dimensions of gender justice in the Iranian Ministry of Sport and Youth by Javad Bani Hassan, Zahrasadat Mirzazadeh, Mahdi Talebpour, Ahamadreza Asgharpourmasouleh

“…Social, economic and political functions are one of the reasons. In Iran, the role of the Ministry of Sports and Youth is very important in managing sports in the country. …”
Get full text

Forest Disturbance Thresholds and Cumulative Hydrological Impacts by Yiping Hou, Xiaohua Wei

“…Determining disturbance thresholds is critically important for supporting forest management to ensure the sustaining of ecological and hydrological functions. However, there are very few quantitative evaluations of forest disturbance thresholds globally. …”
Get full text

Smart-projects of regional development: content, taxonomic identifiers, and project management specifics by S. K. Deliiev, O. O. Zavhorodnia

“…This research builds on the fundamental concept of human-machine intellectual systems. It presents an original interpretation of the “smart-project for regional development” concept and develops a system of taxonomic identifiers. …”
Get full text

In-vehicle localization based on multi-channel Bluetooth Low Energy received signal strength indicator by Gao Yuan, Zhao Ze, Huang Changcheng, Han Chuanqi, Cui Li

“…However, interferences like effects of multipath and reflection of the signals significantly raise great challenges to the positioning accuracy at in-vehicle environment. This article presents a novel high-precision in-vehicle localization method, namely, the LOC-in-a-Car, based on functional exploration and full use of multi-channel received signal strength indicator of Bluetooth Low Energy. …”
Get full text

NATURAL POLYACETYLENE COMPOUNDS by D. A. Konovalov

“…Polyacetylenes are relatively unstable, chemically and biologically active compounds, and present in fungi, microorganisms, marine invertebrates and other organisms except for plants. …”
Get full text

Land use policy and green utilization efficiency in border cities: evidence from northeastern China’s carbon reduction practice by Xuncheng Fan, Lili Zhao

“…Different types of cities present differentiated policy responses.DiscussionIndustrial cities promote technological upgrades through digital transformation. …”
Get full text

APPLICATION OF MODELS OF INFORMATION AND ANALYTICAL SUPPORT SYSTEMS FIRE FIGHTING RESCUE UNITS by O. I. Stepanov, S. A. Khudyakova

“…Objectives It was proposed to review the structure of the fire and rescue divisions management system, based on the decomposition of the forces and means of the subdivisions into fire extinguishing positions and ensuring fire extinguishing actions.Method The structural and functional model of the development of the fire and rescue divisions management system has been clarified, which allows to present the stages of the development of the system as components of a single fire extinguishing process. …”
Get full text

Genomic and transcriptomic analyses provide new insights into the complex impacts of bud mutation in peach by Guo Rui, Zhou Ping, Yan Shaobin, Jin Guang, Li Yong

“…Abstract Bud mutation is an important solution in fruit breeding, but the mechanism of bud mutation remains largely unknown. Here, we present the phenotypic, genomic, and transcriptomic analyses of a peach hairless bud mutation. …”
Get full text

Reconstruction of Scalp Defects with Rotational Flaps: Where Is the Limit? by Konstantinos Seretis, Nikos Bounas, Efstathios G. Lykoudis

“…By combining the principles of tissue biomechanics with the versatility of rotational flaps, surgeons can effectively address a wide range of defects, achieving both functional and esthetic excellence.…”
Get full text

Genetic and Nutritional Dynamics of SynCom in Suppressing Apple Fire Blight by Yejin Lee, Youn Min Ko, Youn-Sig Kwak

“…This study demonstrates that genetic selection using metagenomics can effectively identify microorganisms with potential functional capabilities.…”
Get full text

Facial emotion recognition accuracy in women with symptoms of polycystic ovary syndrome: Reduced fear and disgust perception by Shree Smruthi Venkateshan, Kirsten A. Oinonen

“…These findings are consistent with the theory that androgens affect emotion recognition and suggest implications for PCOS symptoms on women’s emotional well-being and socioemotional functioning.…”
Get full text

Categorical Frailty Phenotype and Continuous Frailty Index: A Conceptual Overview of Frailty and Its Components among Older Persons in India by Ankit Anand, T.S. Syamala, Md Illias Kanchan Sk

“…It will be interesting to examine and compared different model of frailty using the same dataset. The present paper aimed to compare two frailty models and examine the association between socioeconomic status with frailty and frailty components among older persons in India.  …”
Get full text

Harnessing Microbiome, Bacterial Extracellular Vesicle, and Artificial Intelligence for Polycystic Ovary Syndrome Diagnosis and Management by Bhawna Kushawaha, Tial T. Rem, Emanuele Pelosi

“…Recent studies have shown that gut dysbiosis plays a significant role in PCOS pathophysiology, with bacterial extracellular vesicles (BEVs) functioning as critical mediators of the gut–ovary axis. …”
Get full text

Candidate gene identification and marker development for seed coat peeling rate in peanut (Arachis Hypogaea L.) by Hongfei Liu, Ziqi Sun, Feiyan Qi, Xiao Wang, Meng Zhang, Juan Wang, Xiaobo Wang, Ziqiang Mo, Mingbo Zhao, Chenyang Zhi, Mengmeng Wang, Zhiyuan Zhou, Linhong Xu, Wenzhao Dong, Zheng Zheng, Xinyou Zhang

“…The identification of a major QTL qSCPRA05 and the candidate gene Arahy.0C6ZNN may offer valuable targets for further functional research. Moreover, the development of molecular markers linked to SCPR presents a promising tool for marker-assisted selection (MAS), facilitating genetic improvement and accelerating breeding efforts for enhanced seed coat integrity in peanut.…”
Get full text