Assessment of local sensitivity in incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) lesions in intermediate age-related macular degeneration (iAMD) by Frank G Holz, Marlene Saßmannshausen, Thomas Ach, Leon von der Emde, Julius Ameln, Alessandra Carmichael-Martins, Wolf M Harmening

“…However, the corresponding functional impact of these precursor lesions is unknown and needs to be established.Methods and analysis We present a cross-sectional study of four patients with intermediate AMD employing clinical-grade MAIA (stimulus size: 0.43°, ~125 µm) and adaptive optics scanning light ophthalmoscope (AOSLO, stimulus size 0.07°, ~20 µm) based microperimetry (MP) to assess the specific impact of iRORA lesions on retinal sensitivity.Results AOSLO imaging showed overall reduced photoreceptor reflectivity and patches of hyporeflective regions at drusen with interspersed hyperreflective foci in iRORA regions. …”
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Proteomic Responses of the Springtail <i>Folsomia candida</i> to Drought by Yang Wang, Stine Slotsbo, Steffen Y. Bak, Christopher J. Martyniuk, Martin Holmstrup

“…This study facilitates the understanding of the consequences of climate change on soil functioning and fertility.…”
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The status of clinical trials regarding root canal sealers by Ahmad AL Malak, Yasmina EL Masri, Mira Al Ziab, Nancy Zrara, Tarek Baroud, Pascale Salameh

“…ObjectivesThis study aimed to present the results and analyses of clinical trials, including updates on the different functions of root canal sealers.Materials and MethodsIn June 2023, we performed a comprehensive search of ClinicalTrials.gov to identify interventional clinical trials pertaining to root canal sealers. …”
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A Methodological Approach for Assessing the Interaction Between Rural Landscapes and Built Structures: A Case Study of Winery Architecture in Tuscany, Italy by Stefano Bigiotti, Carlo Costantino, Mariangela Ludovica Santarsiero, Alvaro Marucci

“…This paper introduces an adaptable interpretive method applicable across contexts, suitable for professionals and decision-makers. The findings present a framework for evaluating landscape systems, demonstrating how passive and advanced strategies enhance eco-efficiency and landscape perception, and adding ethical, aesthetic, and functional value. …”
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Symptomatic treatment of infantile nystagmus: a systematic review by Xuanwei Li, Xuanwei Li, Bianca Huurneman, Bianca Huurneman, Jeroen Goossens, Jeroen Goossens

“…The diverse causes of IN complicate its differentiation from symptoms secondary to other conditions, presenting challenges for clinical decision-making and systematic review. …”
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Assessing the potential impact of grasshopper outbreaks on Patagonian wetlands through mathematical modelling by Laura Soledad Serrano, Ana Laura Pietrantuono, María Fabiana Laguna, Mariana Weigandt, María Emilia Amadio, Valeria Fernández-Arhex

“…In the Patagonian steppe, wetlands are important ecosystems due to their environmental and ecological functions. Within these ecosystems, there is a wide diversity of phytophagous insects, among which two species of orthoptera are predominant: Dichroplus elongatus (usually considered a pest) and D. vittigerum. …”
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Nonsurgical Treatment of Class III Malocclusion with Both Anterior and Posterior Crossbites Combined with Impacted and Congenitally Missed Teeth by Yahya A. Alogaibi, Ahmed R. Afify, Ahmad A. Al-Fraidi, Ali A. Hassan

“…Class III malocclusions present a great challenge for many orthodontists, especially if malocclusions are found in adult patients and alongside other dental problems. …”
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Chromosome-level genome assembly of rock carp (Procypris rabaudi) by Zhongyi Wang, Miling Ran, Xiaoshuai Liu, Chuang Zhou, Zhaobin Song

“…The assembled genome achieved a BUSCO completeness score of 97.8%, with 45,784 protein-coding genes identified, of which 94.78% were functionally annotated in at least one protein database. …”
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An Ultrasound Prototype for Remote Hand Movement Sensing: The Finger Tapping Case by Stefano Franceschini, Maria Maddalena Autorino, Michele Ambrosanio, Vito Pascazio, Fabio Baselice

“…The system functions as an ultrasound sonar capable of measuring the Doppler spectrum of waves reflected by the hand. …”
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Subacromial-First Approach to Minimize Infraspinatus Damage for Massive Rotator Cuff Tears Repair by Wittawat Boonyanuwat, M.D., Chatchavan Charoenthamruksa, M.D., Adisak Nartthanarung, M.D., Pinkawas Kongmalai, M.D.

“…We present a tendon-preserving approach for massive rotator cuff tears, focusing on the subacromial space rather than entering the glenohumeral joint. …”
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Toward the Human Scale in Smart Cities: Exploring the Role of Active Mobility in Ecosystemic Urbanism by Froylán Correa, Miguel Bartorila, Mónica Ribeiro-Palacios, Gerardo I. Pérez-Soto, Juvenal Rodríguez-Reséndiz

“…Active Mobility (AM) currently presents an opportunity to change the paradigm of the competitive and dispersed city created by motorized mobility, revaluing the role of walking and cycling in generating more sustainable urban ecosystems. …”
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Bailiffs’ Offices in the North Caucasus in the Last Third of the 18^th — First Half of the 19^th Centuries: Evolution of Activity by A. Kh. Abazov, I. R. Nakhusheva

“…It is concluded that the proposed periodization allows to present the dynamics of the activity of the bailiffs in the North Caucasus in the last third of the 18th — first half of the 19th centuries as a complex phenomenon aimed at finding optimal forms of governance of the peoples included in the political and legal space of the Russian Empire.…”
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A homeostatic model of IκB metabolism to control constitutive NF‐κB activity by Ellen L O'Dea, Derren Barken, Raechel Q Peralta, Kim T Tran, Shannon L Werner, Jeffrey D Kearns, Andre Levchenko, Alexander Hoffmann

“…Simulations reveal a homeostatic NF‐κB signaling module in which differential degradation rates of free and bound pools of IκB represent a novel cross‐regulation mechanism that imparts functional robustness to the signaling module.…”
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The Importance of Biobelts from the Point of View of the Biodiversity of Epigeic Groups by Jana Ivanič Porhajašová, Mária Babošová, Peter Schultz, Miroslava Kačániová

“…The aim of the work was to evaluate the abundance, structure and dominance of the occurrence of epigeic groups present in biobelts in the southwestern part of Slovakia. …”
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On the Flow Behavior in Rotor-Stator System with Superposed Flow by Roger Debuchy, Fadi Abdel Nour, Gérard Bois

“…Thus, two innovative weighting functions are tested, leading to new analytical laws relating the core swirl ratio K to the coefficient of flow rate Cqr introduced by Poncet et al. (2005). …”
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A system‐level model for the microbial regulatory genome by Aaron N Brooks, David J Reiss, Antoine Allard, Wei‐Ju Wu, Diego M Salvanha, Christopher L Plaisier, Sriram Chandrasekaran, Min Pan, Amardeep Kaur, Nitin S Baliga

“…Abstract Microbes can tailor transcriptional responses to diverse environmental challenges despite having streamlined genomes and a limited number of regulators. Here, we present data‐driven models that capture the dynamic interplay of the environment and genome‐encoded regulatory programs of two types of prokaryotes: Escherichia coli (a bacterium) and Halobacterium salinarum (an archaeon). …”
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The Morphometric Status of the Macula in Children with Pseudophakia after Surgical Treatment of Congenital Cataracts by L. A. Katargina, T. B. Kruglova, N. S. Egiyan, D. I. Ryabtsev, O. B. Trifonova

“…The paper presents the results of a comprehensive ophthalmic examination which includes, along with traditional methods, optical coherence tomography (taken by Spectralis HRA+OCT, Heidelberg Engineering) of 33 children (50 eyes) aged 1 to 7 years with pseudophakia after extraction of bilateral congenital cataracts (CC). …”
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Nonalcoholic Steatohepatitis in a Patient with Ataxia-Telangiectasia by Trinidad Caballero, Mercedes Caba-Molina, Javier Salmerón, Mercedes Gómez-Morales

“…A-T patients have inactivation of ataxia-telangiectasia-mutated (ATM) protein, which controls DNA double-strand break repair and is involved in oxidative stress response, among other functions; dysfunctional control of reactive oxygen species may be responsible for many of the clinical manifestations of this disease. …”
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An Evaluation of the Adaptive Reuse of Abandoned Buildings by Hanieh Ahmadi Joshaghani, Mohammad Reza Hafezi, Behrooz Mohammad Kari

“…According to the results, the affecting criteria were ranked as follows: environmental factors, architecture and urbanism, social, economic, physical, functional, and technology. In the end, the environmental factor was recognised as the most effective in the adaptive reuse of abandoned buildings, to decide whether to reuse or demolish a building.…”
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Blocked Autophagy by miR-101 Enhances Osteosarcoma Cell Chemosensitivity In Vitro by Zhiqiang Chang, Lifeng Huo, Kun Li, Yiming Wu, Zhenming Hu

“…Studies have shown paradoxical functions of autophagy in tumor development, which has been demonstrated by microRNAs. …”
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