Bacterial Hachiman complex executes DNA cleavage for antiphage defense by Yongqing Cui, Zhikang Dai, Yufei Ouyang, Chunyang Fu, Yanjing Wang, Xueting Chen, Kaiyue Yang, Shuyue Zheng, Wenwen Wang, Pan Tao, Zeyuan Guan, Tingting Zou

“…However, the defense mechanism remains only partially understood. Here, we present the cryo-electron microscopy (cryo-EM) structure of the Hachiman defense system featuring a fusion of Cap4 nuclease domain within HamA. …”
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Acoustic interaction of submerged thin-shell structures considering seabed reflection effects by Xin Zhang, Kai Ai, Sen Yang, Sen Yang, Qingxiang Pei, Qingxiang Pei, Guang Lei, Guang Lei

“…This paper presents a novel approach for simulating acoustic-shell interaction, specifically focusing on seabed reflection effects. …”
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Large-scale predictions of alternative protein conformations by AlphaFold2-based sequence association by Myeongsang Lee, Joseph W. Schafer, Jeshuwin Prabakaran, Devlina Chakravarty, Madeleine F. Clore, Lauren L. Porter

“…These methods often assume that AF2 relies on evolutionary couplings to predict alternative protein conformations, but they perform poorly on fold-switching proteins, which remodel their secondary structures and modulate their functions in response to cellular stimuli. Here we present a method designed to leverage AF2’s learning of protein structure more than evolutionary couplings. …”
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Biomineralization‐Inspired Membranization Toward Structural Enhancement of Coacervate Community by Chunyu Zhao, Xiaoliang Wang, Lianning Li, Hu Huang, Bingzhao Wu, Lei Zhang, Xin Huang

“…Abstract The design and assembly of protocell models that can mimic the features and functions of life present a significant research challenge with the potential for far‐reaching impact. …”
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Characteristic Fingerprint Based on Low Polar Constituents for Discrimination of Wolfiporia extensa according to Geographical Origin Using UV Spectroscopy and Chemometrics Methods by Yan Li, Ji Zhang, Yanli Zhao, Zhimin Li, Tao Li, Yuanzhong Wang

“…The fungus species Wolfiporia extensa has a long history of medicinal usage and has also been commercially used to formulate nutraceuticals and functional foods in certain Asian countries. In the present study, a practical and promising method has been developed to discriminate the dried sclerotium of W. extensa collected from different geographical sites based on UV spectroscopy together with chemometrics methods. …”
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Differences and analogies in thyroid cancer discovered incidentally or by thyroid-related screening: a multicenter study by Laura Croce, Rosaria Maddalena Ruggeri, Camilla Virili, Carlo Cappelli, Marsida Teliti, Pietro Costa, Spyridon Chytiris, Antonio Nicocia, Francesca Coperchini, Maria Flavia Bagaglini, Flavia Magri, Alfredo Campennì, Mario Rotondi

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Enhancing implementation of information and communication technologies for post-discharge care among hospitalized older adult patients: development of a multifaceted implementation... by Dorothy Yingxuan Wang, Eliza Lai-Yi Wong, Annie Wai-Ling Cheung, Zoe Pui-Yee Tam, Kam-Shing Tang, Eng-Kiong Yeoh

“…Additionally, the Implementation Research Logic Model is utilized to synthesize, organize, and visually present the collected data. Results This structured process identified and selected five intervention functions, 11 behavior change techniques, and four policy categories. …”
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Deciphering the role of dietary modifications and gut dysbiosis in Non-Alcoholic Fatty Liver Disease by Meenakshi Vachher, Kohinoor Kaur, Manisha Marothia, Archana Burman, Deepanjana, Savita Bansal

“…Dietary alterations or nutritional interventions have a huge impact on gut microbiota composition and functions. An association between the type of diet, altered gut microbiota, and NAFLD is now being appreciated. …”
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Automatic detection of floating instream large wood in videos using deep learning by J. Aarnink, J. Aarnink, T. Beucler, T. Beucler, M. Vuaridel, V. Ruiz-Villanueva, V. Ruiz-Villanueva

“…<p>Instream large wood (i.e. downed trees, branches, and roots larger than 1m in length and 10 cm in diameter) performs essential geomorphological and ecological functions that support the health of river ecosystems. …”
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Modified Trochanteric Flip Osteotomy in Varus Intertrochanteric Osteotomy for Treatment of Legg–Calvé–Perthes Disease by Andrea Laufer, Carina Antfang, Georg Gosheger, Adrien Frommer, Gregor Toporowski, Henning Tretow, Robert Roedl, Bjoern Vogt

“…<b>Background/Objectives</b>: Legg–Calvé–Perthes disease (LCPD) presents challenges in treatment due to its varied course and unclear etiology. …”
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Enteromorpha prolifera soluble dietary fiber alleviates ulcerative colitis through restoration of mucosal barrier and gut microbiota homeostasis by Yuan-Yuan Ding, Yuan-Yuan Ding, Xin-Yi Tang, Yu Tian, Feng-Long Zhang, Xiang Ding, Meng-Chun Qi, Wei Dong, Chen-Guang Liu

“…BackgroundUlcerative colitis (UC), a recurrent chronic colon inflammation, presents substantial therapeutic challenges due to the frequent adverse effects associated with conventional pharmacological treatments. …”
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Beyond “Fire” and “Ashes”: The Influence of Trait Characteristics on the Response to Mood Stabilizers in Bipolar Disorders by Alfonso Tortorella, Francesca Scopetta, Gianmarco Cinesi, Ilaria Baldini, Antonio Russo, Kety Amantini, Filippo De Giorgi, Giulia Menculini

“…<i>Background:</i> The present study aimed to investigate the clinical correlates of treatment response to mood stabilizers in patients with bipolar disorder (BD), with a specific focus on trait-related characteristics such as impulsivity and affective temperaments. …”
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Porous highly conductive PEDOT film for high-performance supercapacitors by Wanying Zhang, Zhen Su, Bei Qi, Wentao Wang, Shisong Nie, Yingzhi Jin, Jiaxing Song, Lin Hu, Xinxing Yin, Weihua Ning, Xiaoming Yang, Hao Wang, Zaifang Li, Liang Huang

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Validating an IoT implementation framework for supporting industry 4.0 in SMEs: a Delphi and focus group approach by Qusay Adnan Abdulaziz, Hazilah Mad Kaidi, Maslin Masrom, Khairur Rijal Jamaludin, Shamsul Sarip, Suha Ibraheem Hamad, Halim Shah Hamzah

“…Despite recognizing the framework's comprehensiveness, experts highlighted the need for improved functionality and real-time performance, while expressing concerns about complexity. …”
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U.S. UNIVERSITY WEBSITES AS SPECIFIC MULTIMODAL TEXTS by Svitlana V. Fedorenko, Kateryna B. Sheremeta

“…It also employed the system functional (drawing on the provisions of linguistic metafunctions, and focusing on the categories of the grammar of visual design) and the socio-semiotic (grounding on the interrelationship of modes, their compatibility and social needs for which they serve, making meanings) approaches. …”
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Effects of intravenous immunoglobulin on the negatively transformed subpopulations of neutrophilic granulocytes in newborns with congenital pneumonia and neonatal sepsis by I. V. Nesterova, S. V. Kovaleva, G. A. Chudilova, L. V. Lomtatidze, T. V. Smerchinskaya, V. N. Chapurina

“…., congenital pneumonia (CP) and neonatal sepsis (NS), present difficult problems. Searching sensitive and specific severity markers of bacterial inflammatory process as well as early and effective treatment are crucial for the outcome and prognosis of these life-threatening diseases. …”
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Exploring the effect of exchange coupling in (SrFe9.8Al2La0.2O19)1-x/(Co0.7Zn0.3Fe2O4)x nanocomposites synthesised by sol–gel auto combustion method by S.T. Abarna, R. Ezhil Vizhi

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Fuzzy model-based analysis of user feedback for product development insights by Anna Sudár, Borbála Berki, Ildikó Horváth

“…The primary objective of this paper is to present a structured modeling framework, incorporating user feedback to support software product development. …”
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Novel Insights from Comprehensive Bioinformatics Analysis Utilizing Large-Scale Human Transcriptomes and Experimental Validation: The Role of Autophagy in Periodontitis by Liu F, Zhu Z, Zou H, Huang Z, Xiao S, Li Z

“…This investigation involved transcriptomic analysis of a broad range of human samples and complemented by in vitro experimentation.Materials and Methods: We analyzed the transcriptomes of human gingival tissues from individuals with periodontitis and health controls to identify the differential expression of autophagy-related genes (DEARGs) and to investigate their potential interactions and functional pathways. Additionally, protein-protein interaction (PPI) networks were constructed to identify key functional modules and hub genes. …”
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Mechanisms of immune regulation and transplantation immunity in corneal transplants by V. V. Neroev, N. V. Balatskaya, E. V. Chentsova, Kh. M. Shamkhalova

“…At the present time, corneal transplantation (keratoplasty) is one of the most frequent modes of solid tissue transplants in the world. …”
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