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33861
A Disposable Dopamine Sensor Based on Oxidized Cellulose Nanofibril-Modified SPCE
Published 2025-06-01“…Dopamine is a major catecholamine neurotransmitter that plays an essential role in the functioning of the human central nervous system. Imbalances in dopamine levels are associated with neurological disorders and depression. …”
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33862
How to assess water quality change in temperate headwater catchments of western Europe under climate change: examples and perspectives
Published 2022-10-01“…From these examples, we highlight four challenges for research on the relationships between climate and water quality: (i) developing functional typologies of chemical elements, (ii) performing multi-temporal and multi-spatial analysis by aggregating data into water-cycle periods, (iii) decoupling effects of climate conditions and human activities by testing hypotheses using parsimonious models, and (iv) incorporating water quality and aquatic ecosystem health into integrated models. …”
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33863
Novel solitary wave solutions of the (3+1)–dimensional nonlinear Schrödinger equation with generalized Kudryashov self–phase modulation
Published 2025-02-01“…Using the generalized Jacobi elliptic method, we systematically derive novel soliton solutions expressed in terms of Jacobi elliptic and Weierstrass elliptic functions, providing deeper insights into wave dynamics in nonlinear optical media. …”
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33864
Staurosporine as a Potential Treatment for <i>Acanthamoeba</i> Keratitis Using Mouse Cornea as an Ex Vivo Model
Published 2024-09-01“…</i> In addition, proteomic analysis of treated trophozoites revealed that this molecule induced overexpression and a downregulation of proteins related to key functions for <i>Acanthamoeba</i> infection pathways. …”
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33865
Flexible Piezoresistive Film Pressure Sensor Based on Double-Sided Microstructure Sensing Layer
Published 2024-12-01“…The most commonly used microstructure fabrication methods are challenging to apply to ultra-thin functional layers and may compromise the structural stability of the sensors. …”
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33866
Improved TODIM Method for Probabilistic Linguistic MAGDM Based on New Distance Measure
Published 2025-05-01“…Further, some desirable properties of them are studied. Meanwhile, we present an innovative distance measure, deeply anchored in linguistic scale functions, designed to overcome the shortcomings of current distance metrics. …”
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33867
Universal fibroblasts across tissues can differentiate into niche cells for hematopoietic stem cells
Published 2025-05-01“…A meta-analysis of single-cell RNA sequencing datasets across tissues hypothesized that universal fibroblasts present in all organs give rise to distinct tissue-specific fibroblast subsets designated as specialized fibroblasts, including CAR/LepR+ cells. …”
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33868
Mechanically flexible mid-wave infrared imagers using black phosphorus ink films
Published 2025-07-01“…There is an emerging need for mechanically flexible MWIR imagers to broaden their functionality and practicality. Recently, photodetectors using van der Waals (vdW) black phosphorus (BP) flakes have demonstrated highly sensitive room-temperature photodetection. …”
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33869
Human ex vivo dentin-pulp complex preservation in a full crown model
Published 2017-01-01“…Results: Contrary to C-groups, T-groups showed a functional dentin-pulp complex. The treated dentin-pulp complex presents normal histological appearance. …”
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33870
Bifunctional Memristive Behavior of a Dual‐Layer Structure Depending on the Configuration of Charge Transport
Published 2025-08-01“…Abstract This paper presents a method for integrating neuronal and synaptic functions within a thin dual‐layer featuring distinct dielectric strengths. …”
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33871
Cell lineage-resolved embryonic morphological map reveals signaling associated with cell fate and size asymmetry
Published 2025-04-01“…However, studying these shape changes in detail is challenging. Here we present a comprehensive real-time cellular map that covers over 95% of the cells formed during Caenorhabditis elegans embryogenesis, featuring nearly 400,000 3D cell regions. …”
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33872
Dealloying of Quasi-High Entropy Alloys: Fabrication of Porous Noble Metals/Metal Oxides
Published 2025-01-01“…The work provides strategies for the preparation of porous precious metal quasi-HEAs and porous noble metal oxides by the dealloying method. These products present great potential for application as functional materials in hot fields such as catalysis and energy storage.…”
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33873
Persistent Autobiographical Amnesia: A Case Report
Published 2007-01-01“…Brain MRI was normal while H20 brain PET scans demonstrated hypometabolism in the right globus pallidus and putamen after 2 weeks from onset, which was no longer present one year later. The absence of a clear pathomechanism underlying focal amnesia lead us to consider this case as an example of functional retrograde amnesia.…”
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33874
CREATE: cell-type-specific cis-regulatory element identification via discrete embedding
Published 2025-05-01“…However, current approaches for CRE identification are predominantly sequence-based and typically focus on individual CRE types, limiting insights into their cell-type-specific functions and regulatory dynamics. Here, we present CREATE, a multimodal deep learning framework based on Vector Quantized Variational AutoEncoder, tailored for comprehensive CRE identification and characterization. …”
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33875
Sustainable DNA-polysaccharide hydrogels as recyclable bioplastics
Published 2025-08-01“…The process involves chemical oxidation of polysaccharides to produce aldehyde-functionalized derivatives, which subsequently form reversible imine covalent bonds with amine groups in DNA. …”
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33876
Charting new territory: The Plasmodium falciparum tRNA modification landscape
Published 2025-04-01“…Ribonucleoside modifications comprising the epitranscriptome are present in all organisms and all forms of RNA, including mRNA, rRNA and tRNA, the three major RNA components of the translational machinery. …”
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33877
Crystal structures of monomeric BsmI restriction endonuclease reveal coordinated sequential cleavage of two DNA strands
Published 2025-03-01“…Abstract BsmI, a thermophilic Type IIS restriction endonuclease from Bacillus stearothermophilus, presents a unique structural composition, housing two distinct active sites within a single monomer. …”
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33878
Perceptual constancy of pareidolias across paper and digital testing formats in neurodegenerative diseases
Published 2024-11-01“…Our findings demonstrate a practical way of testing pareidolias on smartphones without compromising on the functionality of the test.…”
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33879
UBR-1 deficiency leads to ivermectin resistance in Caenorhabditis elegans
Published 2025-04-01“…Resistance to anthelmintics, particularly the macrocyclic lactone ivermectin (IVM), presents a substantial global challenge for parasite control. …”
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33880
From neglect to necessity: the role of innate immunity in cutaneous squamous cell carcinoma therapy
Published 2025-04-01“…Consequently, targeting innate immune cells to activate anti-tumor immune responses presents significant potential for enhancing immunotherapeutic strategies in cSCC.…”
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