Biomimetic culture substrates for modelling homeostatic intestinal epithelium in vitro by Sorosh Abdollahi, Bahareh Zarin, Maryam Vatani, Fereshteh Vajhadin, Mohsen Hassani, Pezhman Jalali, Keekyoung Kim, Amir Sanati-Nezhad

“…Abstract The increasing interest in utilizing three-dimensional (3D) in vitro models with innovative biomaterials to engineer functional tissues arises from the limitations of conventional cell culture methods in accurately reproducing the complex physiological conditions of living organisms. …”
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Implementation of Chaotic Synchronization and Artificial Neural Networks in Modified OTP Scheme for Image Encryption by Hristina Stoycheva, Georgi Mihalev, Stanimir Sadinov, Krasen Angelov

“…Additionally, ANNs are used to approximate time functions, creating a neural encoding key, which adds an additional layer of complexity to the encryption process. …”
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Characteristics of speech and swallowing in persons with multiple sclerosis by Silva Banović, Osman Sinanović, Mirsad Muftić

“…Speech difficulties impede daily functioning and are often the first sign that other people notice. …”
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A Retrospective Case Series in Fournier’s Disease: And Its Emergency Management et Grafting Technique for Penis Coverage by Domenico Tripodi, Antonio Guastafierro, Federica Gagliardi, Maria Ida Amabile, Eleonora Lori, Roberto Cirocchi, Daniele Pironi, Flavio Forte, Claudio Cannistra, Salvatore Sorrenti

“…We believe that the coverage of the penis using our grafting technique is safe, easily reproducible, and demonstrates excellent esthetic and functional results.…”
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Immunohistochemical Expression of Differentiated Embryonic Chondrocyte 1 and Cluster of Differentiation 44 in Oral Potentially Malignant Disorders by Bianca-Andreea Onofrei, Delia Gabriela Ciobanu Apostol, Mădălina-Gabriela Tanasă, Elena-Raluca Baciu, Cristina Popa, Ana Maria Sciuca, Mihaela Paula Toader, Victor-Vlad Costan

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Profiling of pathogenic variants in Japanese patients with sarcoglycanopathy by Rui Shimazaki, Yoshihiko Saito, Tomonari Awaya, Narihiro Minami, Ryo Kurosawa, Motoyasu Hosokawa, Hiroaki Ohara, Shinichiro Hayashi, Akihide Takeuchi, Masatoshi Hagiwara, Yukiko K. Hayashi, Satoru Noguchi, Ichizo Nishino

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Cryptococcosis in Pediatric Renal Transplant Recipients: Comparative Insights from Adult Cases by Guido Gembillo, Chiara Terzo, Salvatore Silipigni, Luca Soraci, Emmanuele Venanzi Rullo, Ylenia Russotto, Chiara Casuscelli, Maria Elsa Gambuzza, Maria Princiotto, Lorenzo Lo Cicero, Luigi Peritore, Concetto Sessa, Domenico Santoro

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Physiotherapy in Chronic Hemodialysis Patients. Recommendations of the Expert Committee of the Rehabilitation Section at the Polish Society of Nephrology by Wioletta Dziubek, Katarzyna Chojak-Fijałka, Tomasz Gołębiowski, Łukasz Rogowski, Katarzyna Bulińska, Urszula Chrabota, Weronika Pawlaczyk, Kazimierz Ciechanowski, Mariusz Kusztal

“…Recently, measures have been initiated to improve quality of life among patients, which is largely influenced by physical functioning, the ability to undertake physical activity and functional independence. …”
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Structural brain changes in hyperthyroid Graves’ disease: protocol for an ongoing longitudinal, case-controlled study in Göteborg, Sweden—the CogThy project by Rolf A Heckemann, Mats Olof Holmberg, Helge Malmgren, Peter Berglund, Lina Bunketorp-Käll, Birgitta Johansson, Niklas Klasson, Erik Olsson, Simon Skau, Helena Nystrom Filipsson

“…It will provide novel information on the effect of GD on medial temporal lobe structures and cerebral cortex functionality as well as whether these changes are associated with cognitive and affective impairment, hormonal levels and/or autoantibody levels. …”
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Ultrasound-activated miR-195-5p/shikonin nanobubbles remodel immunosuppressive microenvironment via immunogenic cell death to potentiate PD-1/PD-L1 blockade in hepatocellular carci... by Yandi Tan, Qiao Xu, Yezi Chen, Yun Liu, Chaoqi Liu, Xinwu Cui, Yun Zhao

“…To address this critical clinical challenge, we engineered ultrasound (US)-responsive lipid nanobubbles (NBs) co-encapsulating microRNA (miR)-195-5p and shikonin (SK) (designated miR-195-5p/SK-NBs), a dual-functional platform designed to synergize PD-L1 suppression with immunogenic cell death (ICD). …”
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The clinical impact of recent amphetamine exposure in aneurysmal subarachnoid hemorrhage patients by Jeffrey R. Vitt, Roger C. Cheng, Jason Chung, Travis Caton, Bo Zhou, Nerissa Ko, Karl Meisel, Edilberto Amorim

“…Further investigations about localized effects in the posterior circulation and impact on long-term functional outcomes are warranted.…”
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Chronic multimorbidity among older adults in rural South Africa by Stephen Tollman, Francesc Xavier Gómez-Olivé, Joshua A Salomon, Julia K Rohr, Jennifer Manne-Goehler, Angela Y Chang, Collin Payne, Alisha N Wade, Livia Montana

“…We examined the frequencies of the most prevalent combinations of conditions and assessed relationships between multimorbidity and physical and psychological functioning.Results 69.4 per cent (95% CI 68.0 to 70.9) of the respondents had at least two conditions and 53.9% (52.4–55.5) of the sample had at least two categories of conditions. …”
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Modelling soil prokaryotic traits across environments with the trait sequence database ampliconTraits and the R package MicEnvMod by Jonathan Donhauser, Anna Doménech-Pascual, Xingguo Han, Karen Jordaan, Jean-Baptiste Ramond, Aline Frossard, Anna M. Romaní, Anders Priemé

“…Overall, our approach enables robust inference of ecologically interpretable traits combined with environmental modelling allowing to harness traits as bioindicators of soil ecosystem functioning.…”
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The importance of measuring the levels of ionized magnesium in the blood in critically ill patients by Stanojević Marija B., Parezanovic Miro, Biorac Marko, Spasić Svetolik, Kovačević Sanjin, Lopičić Srđan, Nešović Ostojić Jelena

“…Magnesium is a bioessential element with multiple physiological effects relevant for vital body functions. It stabilizes excitable membranes contributing to proper neuromuscular, cardiovascular and respiratory functions. …”
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The Effects of Sourdough Fermentation on the Biochemical Properties, Aroma Profile and Leavening Capacity of Carob Flour by Gemma Sanmartín, Jose A. Prieto, Miguel Morard, Francisco Estruch, Josep Blasco-García, Francisca Randez-Gil

“…However, its high sugar content and the presence of undesirable compounds such as furans present challenges for its use in bread making. This study evaluated the effects of prolonged sourdough fermentation on roasted carob flour, with a focus on microbial dynamics and its functional and technological properties. …”
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A novel indirubin- 3-monoxime derivative I3MV- 8b exhibits remarkable cytotoxicity against multiple myeloma by targeting TRIM28 by Teng Fang, Lanting Liu, Hao Sun, Xiaoyu Zhang, Xiyue Sun, Zhen Yu, Lixin Gong, Shiyi Xie, Yonglong Zhao, Yan Li, Lugui Qiu, Gang An, Bin He, Mu Hao

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Coupling Enteromorpha prolifera-derived N-doped biochar with Cu-Mo2C clusters for selective CO2 hydrogenation to CO by Xueyuan Pan, Caikang Wang, Bei Li, Mingzhe Ma, Hao Sun, Guowu Zhan, Kui Wang, Mengmeng Fan, Linfei Ding, Gengtao Fu, Kang Sun, Jianchun Jiang

“…Unlike traditional activated carbon (AC) supported Cu-Mo2C particles (Cu-Mo2C/AC), the Cu-Mo2C/EPBC not only presents the better graphitization degree and larger specific surface area, but also uniformly and firmly anchors atomic-level Cu-Mo2C clusters due to the existence of pyridine nitrogen. …”
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Unidirectional electric field enables reversible ferroelectric domain engineering by Xingan Jiang, Muzhi Li, Yuanyuan Cui, Xiao Wu, Zunyi Deng, Xiangping Zhang, Jianming Deng, Xiaolei Wang, Dongdong Zhang, Xiangdong Yang, Zhuoyin Peng, Zhao Liang, Xueyun Wang, Weiyou Yang

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Current Treatment Limitations in Age-Related Macular Degeneration and Future Approaches Based on Cell Therapy and Tissue Engineering by P. Fernández-Robredo, A. Sancho, S. Johnen, S. Recalde, N. Gama, G. Thumann, J. Groll, A. García-Layana

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B cells upregulate NMDARs, respond to extracellular glutamate, and express mature BDNF to protect the brain from ischemic injury by Vanessa O. Torres, Jadwiga Turchan-Cholewo, Mary K. Colson, Pavel Yanev, Daimen R.S. Britsch, Katherine M. Cotter, Annabel M. McAtee, Thomas A. Ujas, Domenico Mercurio, Xiangmei Kong, Erik J. Plautz, Chaitanya R. Joshi, Takeshi K. Matsui, Eiichiro Mori, Ambar Cajigas-Hernandez, Kielen Zuurbier, Steven Estus, Mark P. Goldberg, Nancy L. Monson, Ann M. Stowe

“…Lastly, GluN2A, GluN2B, glutamate-induced Ca2+ responses, and BDNF expression were all clinically confirmed in B cells from healthy donors, with BDNF+ B cells present in post-stroke human parenchyma. These data suggest that B cells express functional NMDARs that respond to glutamate, enhance NMDAR signaling with activation, and upregulate mature BDNF expression within the brain. …”
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