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33641
Thermomorphic pneumatic metamaterials: numerous and robust shape-locking under temperature modulation through 4D printing
Published 2025-01-01“…This advance in 4D printing has the potential to significantly enhance its functional capabilities, performance, and applicability, opening up new horizons in additive manufacturing and design.…”
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33642
The impact of a plant-based diet on the menstrual cycle and female fertility
Published 2024-12-01“…Unfortunately, an improperly balanced diet that excludes animal-derived products can, through various mechanisms, lead to deficiencies and disruptions in the functioning of many systems in the body. This review paper aims to present and summarize the findings and current literature on the impact of a plant-based diet on the menstrual cycle and female fertility. …”
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33643
PRMT1 alleviates isoprenaline-induced myocardial hypertrophy by methylating SRSF1
Published 2024-12-01“…In addition, there is an interaction between PRMT1 and SRSF1, whereby PRMT1 reduces the phosphorylation level of SRSF1 via methylation, thus further altering its functional activity and eventually improving MH. Our present study demonstrates that PRMT1 relieves MH by methylating SRSF1, which is expected to provide a new theoretical basis for the pathogenic mechanism of MH and potential drug targets for reducing MH and associated cardiovascular disease.…”
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33644
Differences in care delivery for children and adolescents with cancer in Europe – Results from the SIOPE OCEAN project
Published 2025-06-01“…We used descriptive statistics to present the results. Results: The cancer incidence across Europe was 15/100’000 and 26/100’000 in those aged 0–14 and 15–24 years respectively in 2022. …”
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33645
A Heterogeneously Integrated 256-Element 5G Phased Array: Design, Assembly, Test
Published 2025-01-01“…In this paper, we present the design, assembly, and test of a heterogeneously integrated dual-polarized 256-element 5G phased array covering 24<inline-formula><tex-math notation="LaTeX">$-$</tex-math> </inline-formula>30 GHz. …”
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33646
Targeted-theranostic nanoparticles induce anti-tumor immune response in lung cancer
Published 2025-07-01“…The cyclic Arg-Gly-Asp (cRGD) peptide has a high affinity to RGD-binding integrins overexpressed on various tumor cells, including lung cancer. In the present study, we introduced cRGD peptides onto the surface of AGuIX-Bi NPs using a PEG spacer to form an amide bond with the free amino functions present at the surface of the NPs. …”
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33647
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33648
A suppression-modification gene drive for malaria control targeting the ultra-conserved RNA gene mir-184
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33649
Cognitive deficits in patients with obsessive&ndash;compulsive disorder &ndash; electroencephalography correlates
Published 2016-05-01“…The subgroup of patients with normal cognitive functions (N=9) did not differ in cortical EEG sources from healthy controls.Conclusion: The present results suggest that frontal low-frequency cortical sources of resting-state EEG rhythms can distinguish groups of cognitively impaired and cognitively intact patients with OCD. …”
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33650
Electronic Educational Resource as a Source and Means of Developing Digital Education
Published 2023-10-01“…Digital methods of presenting and displaying information have sufficient capabilities for this. …”
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33651
The Aporia of Reality/Imagination: Uncertainty in Selected Iranian Monodramas and Surrealist Dramas
Published 2025-06-01“…This research explores how the aporia of reality and imagination functions as a rhetorical tool that renders drama as self-deconstructive. …”
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33652
Insights into a rapid access angina clinic (RAAC): are we capturing the right cohort of patients?
Published 2025-06-01“…Results and discussion: 145 patients were assessed in the RAAC. The most common presenting symptom was chest pain (48%), followed by shortness of breath (32%) and palpitations (30%). …”
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33653
Fungi in Mangrove: Ecological Importance, Climate Change Impacts, and the Role in Environmental Remediation
Published 2025-04-01“…The objective of this narrative synthesis is to point out the diversity of fungi present in mangrove sediments, emphasizing how the impacts of climate change and anthropogenic pollution influence the composition and functionality of these communities. …”
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33654
Cognitive performance of neuromyelitis optica patients: comparison with multiple sclerosis Desempenho cognitivo de pacientes com neuromielite óptica: comparação com esclerose múlti...
Published 2013-06-01“…<p id="para1">The aim of the present research was to investigate cognitive pattern of patients with neuromyelitis optica (NMO) and to compare it with multiple sclerosis (MS) patients' performance. …”
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33655
Identifying and Validating Indicators of Ritualism in the Iranian Higher Education System: A Mixed-Methods Study
Published 2025-06-01“…Neglecting its indicators in the core functions of the university—teaching, research, and services—can lead to institutions that lack quality and fail to make a significant impact on society, both formally and functionally. …”
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33656
Genome editing of TXNIP in human pluripotent stem cells for the generation of hepatocyte-like cells and insulin-producing islet-like aggregates
Published 2025-05-01“…Conclusions Our study demonstrates that TXNIP deficiency does not improve the differentiation or functionality of HLCs and SC-islets. We present the generation and characterisation of TXNIP −/− and TXNIP +/+ H1-hESCs, HLCs, and SC-islets as valuable models for future studies on the role of TXNIP in metabolic cell biology.…”
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33657
Cell types and neuronal genetic architecture in the rat CSF-contacting nucleus and the role of 5-HT in this nucleus in mediating morphine addiction through the brain–CSF circuit
Published 2025-06-01“…IntroductionTo elucidate the cellular composition of the cerebrospinal fluid-contacting nucleus, establish a comprehensive gene expression database for this nucleus, and investigate its potential functional roles.Methodswe used single-cell sequencing technology combined with Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses to characterize the transcriptional architecture of the CSF-contacting nucleus and elucidate its potential biological functions. …”
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33658
Gender Differences in Clinical and Biochemical Variables of Patients Affected by Bipolar Disorder
Published 2025-02-01“…<b>Introduction:</b> Bipolar disorder (BD) affects over 1% of the global population and significantly impacts psychosocial functioning and life expectancy. This manuscript has the objective of investigating gender differences in the clinical and biochemical parameters of patients affected by BD. …”
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33659
Pharmacological and structural characterization of vibostolimab, a novel anti-TIGIT blocking antibody for cancer immunotherapy
Published 2025-08-01“…Functional experiments in mouse models demonstrated additional detailed biological mechanisms of the mouse equivalent of vibostolimab, including the differentiating role of myeloid cell activation in addition to improved T cell cytolytic activity, both of which are further enhanced by anti-PD-1 combination therapy.Conclusions Vibostolimab is a novel anti-TIGIT antibody that completely blocks CD155 binding and induces T-cell activation. …”
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33660