Revisiting CPSF30-mediated alternative polyadenylation in Arabidopsis thaliana. by Guijie Hao, Lichun Zhou, Huazhen Liu, Pradeep Kachroo, Arthur G Hunt

“…Importantly, CPSF30-associated APA had at best a small impact on mRNA functionality. These results necessitate the formulation of new hypotheses for mechanisms by which CPSF30-mediated APA influences physiological processes.…”
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Low Dose Pregabalin Improves Gastrointestinal Symptoms of Crohn’s Disease by Antonio Maria D’Onofrio, Federica Di Vincenzo, Gaspare Filippo Ferrajoli, Franco Scaldaferri, Giovanni Camardese

“…Several studies demonstrated that patients with IBD more frequently experience symptoms of common mental disorders, such as anxiety and depression, because of bidirectional communication through the gut-brain axis and the chronicity of symptoms, as well as because of impaired quality of life and reduced social functioning. However, psychological conditions of affected patients are often underestimated and not fully considered. …”
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Environmental Benefits of Fluorogypsum Reuse in the Production of Construction Materials by Bauyrzhan Rakhadilov, Aidar Kengesbekov, Manarbek Kylyshkanov, Lyaila Bayatanova, Abdulina Saule Amangeldyevna, Moldir Bayandinova

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Exploring Atypical Origins of Trismus: Surgical Solutions for Rare Pathologies—Insights from Rare Clinical Cases by Ioanna Kalaitsidou, Mathieu Gass, Dimitris Tatsis, Sherin Khalil, Christian Schedeit, Simon David Marjanowski, Sarah Wiegner, Benoît Schaller

“…<b>Background</b>: Trismus, or restricted mouth opening, can present significant challenges in oral and maxillofacial surgery and trigger substantial functional and psychosocial disabilities. …”
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Designing CITOBOT: A portable device for cervical cancer screening using human-centered design, smart prototyping, and artificial intelligence by Marcela Arrivillaga, Paula C. Bermúdez, Juan Pablo García-Cifuentes, Hernán Darío Vargas-Cardona, Daniela Neira, Maria del Mar Torres, Mérida Rodríguez-López, Daniela Morales, Bleider Arizala

“…Cervical cancer remains a leading cause of mortality in its invasive stages, presenting a significant global public health challenge, particularly in low- and middle-income countries. …”
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Gut microbiota modulate radiotherapy-associated antitumor immune responses against hepatocellular carcinoma Via STING signaling by Zongjuan Li, Yang Zhang, Weifeng Hong, Biao Wang, Yixing Chen, Ping Yang, Jian Zhou, Jia Fan, Zhaochong Zeng, Shisuo Du

“…Mechanistically, gut microbiome dysbiosis impairs antitumor immune responses by suppressing antigen presentation and inhibiting effector T cell functions through the cGAS–STING–IFN-I pathway. …”
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Proteome profiling of human lung epithelial cells unveils distinct patterns of protein expression in response to SARS-CoV-2 ORF3a by Apoorva, Astha Shukla, Atul Kumar, Saurabh Singh, Sunit K. Singh

“…These proteins may play a role in modulating the host's cellular immune functions in response to SARS-CoV-2 ORF3a. Taken together, the present study demonstrates key proteins involved in ORF3a-mediated dampened immune response in human lung epithelial cells, which may facilitate viral replication. …”
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Amplified Sensitivity in SERS Detection of L1CAM With Silver Plasmonic Mesoporous Silica Capsules on an Imprinted Films by Yuselis Castaño‐Guerrero, Belén Arjones‐Fernández, Felismina T.C. Moreira, Ramon A. Alvarez‐Puebla, Miguel A. Correa‐Duarte, H. Águas, M. Goreti F. Sales

“…Abstract This study presents a novel approach for dual detection, leveraging a combination of a Raman reporter‐bearing nanomaterial and molecular imprinting polymers (MIP). …”
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Computational modeling of thermal therapy for porous osteosarcoma knee bone tumors using magnetized copper oxide nanoparticles by Muhammad Suleman, Usama Majeed, Sami Ullah Khan, Nermeen Abdullah, Nidhal Becheikh, Lioua Kolsi

“…This thermal therapy may preserve the join functionality during the limb-salvage procedures. Objectives: This continuation presents a computational approach to simulating thermal treatment of porous knee Osteosarcoma tumors with applications of magnetized copper oxide nanoparticles. …”
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A New Multi-Parametric MRI-Based Scoring System for Degenerative Cervical Myelopathy: The Severity on Imaging Myelopathy Score (SIMS) by Alexis Morgado, Julien Berthiller, Fabien Subtil, Donato Creatura, Gildas Patet, Nathalie André-Obadia, Cédric Yves Barrey

“…<b>Background/Objectives:</b> Degenerative cervical myelopathy (DCM) is the leading cause of functional disabilities of spinal origin in people over 50 years old. …”
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Electronic Medical Record Inaccuracies: Multicenter Analysis of Challenges with Modified Lung Cancer Screening Criteria by Candice L. Wilshire, Carson C. Fuller, Christopher R. Gilbert, John R. Handy, Kimberly E. Costas, Brian E. Louie, Ralph W. Aye, Alexander S. Farivar, Eric Vallières, Jed A. Gorden

“…Each individual’s EMR was searched for COPD diagnostic terms and the presence of a diagnostic pulmonary functionality test (PFT). An unsubstantiated COPD diagnosis was defined by an individual’s EMR containing a COPD term with no PFTs present, or the presence of PFTs without evidence of obstruction. …”
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A Novel Protocol for Culturing Polarized Proximal Tubular Epithelial Cells from Kidney Biopsies: Enhancing Platforms for Drug Excretion and Nephrotoxicity Studies by Tadej Petreski, Lidija Gradišnik, Luka Varda, Polona Kovačič, Jurij Dolenšek, Andraž Stožer, Sebastjan Bevc, Uroš Maver

“…Cells cultured on Transwell plates exhibited native polarization, expressing transporters crucial for drug excretion on apical and basolateral surfaces. We present two robust protocols for isolating and characterizing PTECs, offering a scalable method to obtain functional, polarized cells from scarce biopsy material. …”
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A Review on Pulsed Laser Preparation of Quantum Dots in Colloids for the Optimization of Perovskite Solar Cells: Advantages, Challenges, and Prospects by Liang Sun, Yang Li, Jiujiang Yan, Wei Xu, Liangfen Xiao, Zhong Zheng, Ke Liu, Zhijie Huang, Shuhan Li

“…At present, large amounts of available nanomaterials for surface modification of the perovskite films are extensively investigated, mainly including nanocrystals, nanorods, nanoarrays, and even colloidal quantum dots (QDs). …”
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Chromosome-level genome assembly, reannotation and decoding of a Trichomonas vaginalis clinical isolate from Shiyan, Central China by Yanqing Zhao, Yinjie Lian, Wei Guan, Peng Wu, Shuguo Yang, Jian Li

“…Although many strains are widely present in China, no genomic information is available for relevant studies. …”
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Unveiling the Complexities of Hereditary Angioedema by Cristina Violeta Tutunaru, Oana Maria Ică, George G. Mitroi, Carmen Daniela Neagoe, George F. Mitroi, Olguța Anca Orzan, Beatrice Bălăceanu-Gurău, Simona Laura Ianoși

“…Despite the differences in C1-INH functionality, all three types of HAE manifest with similar clinical symptoms. …”
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California Stress, Trauma, and Resilience Study (CalSTARS) protocol: A multiomics-based cross-sectional investigation and randomized controlled trial to elucidate the biology of AC... by Lauren Y. Kim, Sophia Miryam Schüssler-Fiorenza Rose, Summer Mengelkoch, Daniel P. Moriarity, Jeffrey Gassen, Jenna C. Alley, Lydia G. Roos, Tao Jiang, Arash Alavi, Durga Devi Thota, Xinyue Zhang, Dalia Perelman, Tamar Kodish, Janice L. Krupnick, Michelle May, Katy Bowman, Jenna Hua, Yaping Joyce Liao, Alicia F. Lieberman, Atul J. Butte, Patricia Lester, Shannon M. Thyne, Joan F. Hilton, Michael P. Snyder, George M. Slavich

“…Adverse Childhood Experiences (ACEs) are very common and presently implicated in 9 out of 10 leading causes of death in the United States. …”
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Ideas and perspectives: How sediment archives can improve model projections of marine ecosystem change by I. Hochfeld, B. A. Ward, A. Kremp, J. Romahn, J. Romahn, J. Romahn, A. Schmidt, A. Schmidt, M. Bálint, M. Bálint, M. Bálint, L. Becks, J. Kaiser, H. W. Arz, S. Bolius, L. S. Epp, M. Pfenninger, C. A. Klausmeier, E. Litchman, J. Hinners

“…<p>Global warming is a major threat to marine biodiversity and ecosystem functioning, with consequences that are yet largely unknown. …”
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Mild opening procedure to obtain open-ended yet long single-wall carbon nanotubes for subsequent filling by Aina Fitó-Parera, Miguel Ángel López Carrillo, Marcel Erwan Tonye, Maksiem Erkens, Pegie Cool, Wim Wenseleers, Salomé Forel, Sofie Cambré

“…Encapsulation of molecules inside the hollow core of single-wall carbon nanotubes (SWCNTs) has become an interesting research field to create new functionalities. To fill the SWCNTs, as-synthesized SWCNTs first need to be opened. …”
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Disk Kinematics at High Redshift: DysmalPy’s Extension to 3D Modeling and Comparison with Different Approaches by Lilian L. Lee, Natascha M. Förster Schreiber, Sedona H. Price, Daizhong Liu, Reinhard Genzel, Ric Davies, Linda J. Tacconi, Taro T. Shimizu, Amit Nestor Shachar, Juan M. Espejo Salcedo, Stavros Pastras, Stijn Wuyts, Dieter Lutz, Alvio Renzini, Hannah Übler, Rodrigo Herrera-Camus, Amiel Sternberg

“…We present and test the 3D fitting functionality of DysmalPy , examining how well it recovers the intrinsic disk rotation velocity and velocity dispersion, using a large suite of axisymmetric models, covering a range of galaxy properties and observational parameters typical of z ∼ 1−3 star-forming galaxies. …”
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Intelligent Transportation System With 5G Vehicle-to-Everything (V2X): Architectures, Vehicular Use Cases, Emergency Vehicles, Current Challenges, and Future Directions by Vaishali Pawar, Nilima Zade, Deepali Vora, Vaishali Khairnar, Aurenice Oliveira, Ketan Kotecha, Ambarish Kulkarni

“…The current study contributes in the direction of future research of smart India @2047 in connected vehicles. The study presents the diverse aspects of 5G V2X as a comprehensive overview of Vehicle-to-Everything (V2X) technology that covers the significant scope of V2X technology, including its development, components, functionality, use cases, and future potential. …”
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