Strengthening health system's capacity for pre-exposure prophylaxis for adolescent girls and young women and adolescent boys and young men in South Africa (SHeS'Cap-PrEP): Protocol... by Edward Nicol, Trisha Ramraj, Mbuzeleni Hlongwa, Wisdom Basera, Ngcwalisa Jama, Carl Lombard, Tracy McClinton-Appollis, Darshini Govindasamy, Desiree Pass, Noluntu Funani, Sarah Aheron, Ariana Paredes-Vincent, Jennifer Drummond, Mireille Cheyip, Sibongile Dladla, Jason Bedford, Cathy Mathews

“…Findings from the study will be communicated to the study population and results will be presented to stakeholders and at appropriate local and international conferences. …”
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Prevalence and factors associated with insomnia among firefighting personnel in Dhaka division, Bangladesh by Mohammad Delwer Hossain Hawlader, Koustuv Dalal, Farah Sabrina, Md. Farhan Ibne Faruq, Nurjahan Binte Munaf, Ahmed Hossain, Md. Golam Kibria

“…The findings of this study highlight the need for sleep health promotion programs in firefighting staff.…”
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Immunogenetic profile of MIC (A, B) HLA loci linked to MHC antigenic complex in Russians of the Chelyabinsk Region by A. L. Burmistrova, M. N. Vavilov, D. S. Stashkevich, T. A. Suslova

“…As based on calculated genetic distances (according to Ney) for the MICA locus, the dendrogram and scatter plot were designed by means of multidimensional scaling (MDS) method, presenting location of 30 world populations, including data on Russians in Chelyabinsk Region. …”
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THE PECULIARITIES OF CALCIUM-PHOSPHORUS METABOLISM IN YOUNG CHILDREN by E.G. Yaroshenko, I.I. Sokolova

“…The use of calcium and phosphorus in the framework of the caries prevention programs is recognized as one of the most effective ways to prevent this disease. …”
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Effects of feeding 3-nitrooxypropanol for methane emissions reduction on income over feed costs in the United States by M.R. Pupo, L.F. Ferraretto, C.F. Nicholson

“…These effects on IOFC indicate that under present economic conditions, dairy farmers will need to be compensated by participation in carbon credits programs, provided other incentives for emissions reduction, or both. …”
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Evaluating insecticide susceptibility in major African malaria vectors: a meta-analysis and systematic review by Awoke Minwuyelet, Delenasaw Yewhalaw, Delenasaw Yewhalaw, Andrea Sciarretta, Getnet Atenafu

“…Finally, the results of the original articles are presented in tables, graphs, and maps.ResultsIn total, 61 relevant articles were retrieved and extracted from 1,794 accessed articles. …”
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Misconceptions on COVID-19 Risk Among Ugandan Men: Results From a Rapid Exploratory Survey, April 2020 by Keneth Iceland, Kasozi, MacLeod, Ewan, Ssempijja, Fred, Mahero, Michael W., Matama, Kevin, Musoke, Grace Henry, Bardosh, Kevin, Ssebuufu, Robinson, Wakoko-Studstil, Florence, Echoru, Isaac, Tiyo Ayikobua, Emmanuel, Mujinya, Regan, Nambuya, Grace, Onohuean, Hope, Zirintunda, Gerald, Ekou, Justine, Welburn, Susan Christina

“…Overall, most respondents considered children less vulnerable (OR = 1.12, 95% CI: 0.55–2.2) to COVID-19 than adults, that children present with less symptoms (OR = 1.57, 95% CI: 0.77–3.19), and that there would be less mortality in children (OR = 0.92, 95% CI: 0.41–1.88). …”
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Cancer cell-specific PD-L1 expression is a predictor of poor outcome in patients with locally advanced oral cavity squamous cell carcinoma by Thu Nguyen, Minyu Wang, Sean Macdonald, David Goode, Sevastjan Kranz, Paul Joseph Neeson, Kevin Thia, Joseph A Trapani, Lei Qin, Simone Belobrov, David Wiesenfeld

“…Background Locally advanced oral cavity squamous cell carcinoma (OCSCC) presents a significant clinical challenge despite being partially responsive to standard treatment modalities. …”
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Deep learning and genomic best linear unbiased prediction integration: An approach to identify potential nonlinear genetic relationships between traits by F. Shokor, P. Croiseau, H. Gangloff, R. Saintilan, T. Tribout, T. Mary-Huard, B.C.D. Cuyabano

“…This possibility of nonlinear genetic relationships between traits offers a different perspective into multitrait evaluations, with potential to further improve selection strategies in commercial livestock breeding programs. This is particularly relevant when integrating new traits into multitrait evaluations or incorporating new subpopulations, which may introduce different forms of nonlinearity. …”
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Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice by Onno Kranenburg, Hergen Spits, Julien Villaudy, Madalina Cercel, Miriam Koopman, Cornelis J A Punt, Jamila Laoukili, Andre Verheem, Inne H M Borel Rinkes, Emre Küçükköse, Balthasar A Heesters, Susan van Hal, Sylvia F Boj, Jeanine M L Roodhart

“…The mechanisms underlying this site-specific benefit of ICB are unknown.Methods We created a novel model for spontaneous multiorgan metastasis in MSI-H CRC tumors by transplanting patient-derived organoids (PDO) into the cecum of humanized mice. Anti-programmed cell death protein-1 (PD-1) and anti-cytotoxic T-lymphocytes-associated protein 4 (CTLA-4) ICB treatment effects were analyzed in relation to the immune context of primary tumors, liver metastases, and peritoneal metastases. …”
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Acceptability of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine plus dihydroartemisinin-piperaquine in Papua New Guinea: a qualitative stu... by Elvin Lufele, Sophie Pascoe, Alice Mengi, Alma Auwun, Nalisa Neuendorf, John W. Bolnga, Moses Laman, Stephen J. Rogerson, Kamala Thriemer, Holger W. Unger

“…Due to high-grade Plasmodium falciparum resistance to SP, novel treatment regimens need to be evaluated for IPTp, but these increase pill burden and treatment days. The present qualitative study assessed the acceptability of IPTp-SP plus dihydroartemisinin-piperaquine (DP) in Papua New Guinea, where IPTp-SP was implemented in 2009. …”
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A Novel 14-Gene Panel Associated With Efferocytosis for Predicting Pancreatic Cancer Prognosis Through Bulk and Single-Cell Databases by Yaheng Wu, Lin Zhao, Dingyan Yi, Zhihua Tian, Bin Dong, Chunxiang Ye, Jingtao Liu, Huachong Ma, Wei Zhao

“…Background: Efferocytosis (ER) plays a crucial role in the programmed clearance of dead cells, a process that is mediated by phagocytic immune cells. …”
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Determinants of Caregivers’ Ability to Accurately Detect Acute Malnutrition Using Color-Coded Mid-Upper Arm Circumference Tape and Pitting Edema by Benson C Singano, Collina A Tchongwe, Numeri C Geresomo, Tinna Ng’ong’ola-Manani, Aaron T Chikakuda, Alfred Ngwira, Stanley Mwase, Elsie Mawala, Benson Kazembe, Emma Budalla, Alexander A Kalimbira

“…More data and further studies are required to validate the present results.…”
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Screening for Drought Tolerance Within a Common Bean (<i>Phaseolus vulgaris</i> L.) Landrace Accessions Core Collection from the Lazio Region of Italy by Enrica Alicandri, Ester Badiani, Anna Rita Paolacci, Emilio Lo Presti, Roberta Caridi, Roberto Rea, Francesco Pati, Maurizio Badiani, Mario Ciaffi, Agostino Sorgonà

“…In the present work, a subset extracted from a core collection of common beans (<i>Phaseolus vulgaris</i> L.) landrace accessions from the Lazio region in central Italy was used to identify the most suitable drought-tolerant or -susceptible genotypes. …”
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Neck pain burden in China and G20 countries: an analysis of 1990–2021 with a 30-year forecast for China by Huale Li, Huale Li, Zhichun Chang, Zhichun Chang, Ting Qin, Ting Qin, Yanfang Li, Yanfang Li, Mingren Hu, Xinjing Yang, Jun Li, Jun Li, Yufeng Xie, Yufeng Xie

“…The analysis is conducted via the R programming language, with joinpoint regression employed to calculate the APC and AAPC. …”
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A novel key virulence factor, FoSSP71, inhibits plant immunity and promotes pathogenesis in Fusarium oxysporum f. sp. cubense by Shuang Liu, Junyu Wu, Yinhui Sun, Yun Xu, Siyu Zhou, Peiping Luo, Zhibiao Wang, Daipeng Chen, Xiaofei Liang, Zhensheng Kang, Li Zheng

“…Here, we characterize a novel effector protein, FoSSP71, from Foc, which was significantly induced during the early stages of the Foc4 banana interaction and could suppress BAX-triggered programmed cell death in Nicotiana benthamiana. Transient expression of FoSSP71 in N. benthamiana leaves could weaken the upregulation expression of genes involved in the SA signaling pathway induced by flg22 and significantly reduce both reactive oxygen species bursts and callose accumulation. …”
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Generating evidence to inform responsive and effective actions for Aboriginal and Torres Strait Islander adolescent health and well-being: a mix method protocol for evidence integr... by Alex Brown, Peter Azzopardi, Jaameeta Kurji, Karla Canuto, Rachel Reilly, Seth Westhead, Odette Pearson, Daniel McDonough, Salenna Elliott, India Shackleford, Brittney Andrews, Felicity Andrews, Sally Cooke, Mahlia Garay, Thomas Harrington, Corey Kennedy, Jaeda Lenoy, Monique Maclaine, Hannah McCleary, Lorraine Randall, Hamish Rose, Daniel Rosendale, Jakirah Telfer, Tina Brodie, James Charles

“…Background Australia does not have a national strategy for Aboriginal and Torres Strait Islander adolescent health and as a result, policy and programming actions are fragmented and may not be responsive to needs. …”
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Armonizando el cuidado: efectos de la música en directo en el bienestar de los pacientes oncológicos e intérpretes en el ámbito hospitalario by Raquel Caballero de la Calle, María Encarnación Fernández Contreras, Miguel Ángel García Garrido, Patricia Ferrero Sereno, Ana Ruiz Rodríguez, Raquel Badillo de Santos, María Nieves Moro-Tejedor, Miriam Leñero-Cirujano

“…This research project stems from a collaborative and interdisciplinary effort between two undergraduate programs: Nursing and Musical Performance. Objectives. …”
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Pharmacological and structural characterization of vibostolimab, a novel anti-TIGIT blocking antibody for cancer immunotherapy by Hongmei Wang, Maribel Beaumont, Wendy Blumenschein, Laurence Fayadat-Dilman, Mingmei Cai, Jing Yuan, Douglas Wilson, Thierry O Fischmann, Jeanne Baker, Tanya Keenan, Daniel Malashock, Eunseon Ahn, Komal Pradhan, Jeffery Grein, Srishti Chakravorty, Soheila Bahmanjah, David Ban, Ellen Chien, Mark Hsieh, Todd Mayhood, Janica C Wong, Mark A McCoy, Sybil M G Williams, Wolfgang Seghezzi, Jin-Hwan Han

“…From experiments using a mouse tumor model and mouse surrogate anti-TIGIT antibody, we demonstrate direct evidence where it not only activates cytotoxic T cells but also induces the activation of antigen-presenting cells. The clinical relevance of vibostolimab, based on these mechanisms, in combination with pembrolizumab was recently tested in registrational trials.…”
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Combination of HDAC inhibition and cytokine enhances therapeutic HPV vaccine therapy by Jeffrey Schlom, James L Gulley, Caroline Jochems, Sofia R Gameiro, Wiem Lassoued, Daniel Burnett, Lisa K Poppe, Nicholas Roller, Miriam Marlene Medina-Enríquez, Katherine E Lothstein, Asma S Khelifa, Masaya Miyamoto

“…Background Human papillomavirus (HPV)-associated malignancies continue to present a major health concern despite the development of prophylactic vaccines. …”
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