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161
3-Methyl-4-Nitrobenzoate Derivates as Antifungal Drug Candidates: Biological and In Silico Evaluation
Published 2025-01-01“…Modeling studies of 6, the most bioactive compound against C. guilliermondii, demonstrated that it interacted with TPMK protein, which has been proposed as a molecular target in studies of potential antifungal agents. Finally, the preliminary SAR study of this series furnished information on possibly structural features that may affect the antifungal activity, like the importance of alkyl side chains for bioactivity.…”
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162
Baseline hydro-geochemical characteristics of groundwater in Abu Ali watershed (Northern Lebanon)
Published 2025-02-01“…The remaining two groups consist mostly of wells exploiting the Miocene aquifer at lower altitudes, where agricultural activity is more intense. Finally, this study provides a preliminary assessment of Abu Ali’s groundwater hydrogeochemistry, and further investigations are certainly needed.…”
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163
Chemical Fingerprint and Metabolic Profile Analysis of Tianshu Tablets by Ultra-High Performance Liquid Chromatography/Quadrupole-Time of Flight Mass Spectrometry
Published 2019-01-01“…Hydroxylation and glucuronidation were finally confirmed as the main metabolic pathways. …”
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164
Rapid Identification and Quality Evaluation of Medicinal Centipedes in China Using Near-Infrared Spectroscopy Integrated with Support Vector Machine Algorithm
Published 2019-01-01“…Compared with the features and advantages of these two models, the PLS-SVR model had better performance and stronger prediction capacity, and it was finally regarded as the optimal quantitative analysis model to predict nitrogen content. …”
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165
Optimization of a Continuous Hybrid Impeller Mixer via Computational Fluid Dynamics
Published 2014-01-01“…Afterward, the residence time distribution (RTD) was determined using the respective parameters. Finally, the Fluent-predicted RTD and the experimentally measured RTD were compared. …”
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166
Big Data-Based Boring Indexes and Their Application during TBM Tunneling
Published 2021-01-01“…Subsequently, the defined boring indexes are verified using performance prediction of 291 cyclic tunneling processes. Finally, a preliminary application of support measure suggestions is conducted using the statistical features of boring indexes, where certain criteria are proposed and verified. …”
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167
Probable Relationship between COVID-19, Pollutants and Meteorology: A Case Study at Santiago, Chile
Published 2021-01-01“…The Hurst exponent was found to be greater than 0.5 and less than 1 for all time-series, indicating positive long-term autocorrelation. Finally, the correlation dimension was less than 5, revealing that new time-series constructed are not random.…”
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168
Typhoon Maria Precipitation Retrieval and Evolution Based on the Infrared Brightness Temperature of the Feng-Yun 4A/Advanced Geosynchronous Radiation Imager
Published 2020-01-01“…Finally, based on the AGRI channel brightness temperature of a 10.8-micron window channel, we applied the membership degree information of a typhoon’s dominant cloud system from the fuzzy c-means (FCM) clustering method to modify precipitation retrieval results. …”
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169
HVSR Analysis of Rockslide Seismic Signals to Assess the Subsoil Conditions and the Site Seismic Response
Published 2018-01-01“…This can be related to the indirect effect of temperature on rock mass conditions and further extensive studies (also in the time frequency domain) are required to better comprehend this dependency. Finally, the continuous on-line data reveal interesting applications to provide near-real time warning systems for emerging potentially disastrous rockslides.…”
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170
A Study of Occupational Therapy Strategies and Psychological Regulation of Students’ Internet Addiction in the Mobile Social Media Environment
Published 2022-01-01“…Based on the definition of Internet use peer pressure, a preliminary scale with 2 dimensions of specific behavioral pressure and psychological cognitive pressure was developed. …”
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171
Medición "in situ" de la permeabilidad al aire del hormigón: status quo Concrete air permeability "in situ "test status quo
Published 2010-01-01“…<br>The authors have been involved in the creation, preliminary tests and development of the "Torrent Method", which is intended to test air permeability in concrete. …”
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172
Elevated ALOX12 in renal tissue predicts progression in diabetic kidney disease
Published 2024-12-01“…Further immunofluorescence double staining showed that ALOX12 was expressed in both proximal tubules and distal tubules. Finally, the diagnostic value of the identified gene in the progression of DKD was assessed using receiver operating characteristic (ROC) curve analysis. …”
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173
Frequency Diverse Array for Signal Geofencing in Wireless Communications: Does it Work?
Published 2025-01-01“…Frequency offset, number of elements and their spacing represent further project parameters. Finally, a preliminary assessment of the multipath effect on the focus task shows that the performance of frequency diverse arrays can be affected by complex propagation conditions and deserve further investigations.…”
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174
Exploring the Mechanism of Antioxidant Action of Bitter Almond Based on Network Pharmacology and Molecular Docking Techniques
Published 2023-01-01“…A network pharmacology approach was used to investigate the main active ingredients, key targets, and mechanisms of action of bitter almond antioxidants, and preliminary validation of the relevant targets was performed using molecular docking techniques. …”
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175
Freezing Temperature Field of FSPR under Different Pipe Configurations: A Case Study in Gongbei Tunnel, China
Published 2021-01-01“…It was recommended to strengthen the temperature monitoring at the pipe wall in the preliminary stage of the freezing construction to ensure the water sealing effect between the pipes. …”
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176
AirStrum: A virtual guitar using real-time hand gesture recognition and strumming technique
Published 2024-12-01“…Additionally, this model incorporates a velocity detection function for the strumming hand. Finally, the proposed system can play different sounds by inferring both the played chord and the strumming velocity from human actions. …”
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177
Archéologie d’un jardin de sculptures du xxe siècle
Published 2011-01-01“…This work will be divided into three stages : collecting (archives, oral evidences, letters, novels...), data production (texts, photographs), careful study of these information according to an experimental protocol and finally, connecting all the produced data together in a book combining text and photography.…”
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178
Aging restricts the initial neural patterning potential of developing neural stem and progenitor cells in the adult brain
Published 2025-01-01“…Thus, the embryonic and adult-derived NSPCs for cardinal characteristics were analyzed, and then, the expression of candidate genes related to neural patterning using real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR) was evaluated at various stages of embryonic (E14 and E18), neonatal, and adult brains. Finally, it was assessed the effect of cell attachment and passage on the initial neural patterning of NSPCs.ResultsThe analysis of gene expression revealed that although temporal patterning is maintained in vitro, it shows a decrease over time. …”
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179
Design of a public health emergency equipment system for bioterrorism events in public places based on literature review, scenario analysis and Delphi consultation
Published 2024-10-01“…Finally, the Delphi method was used to revise and improve the plan. …”
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180
Characterization and Properties of Activated Carbon Prepared from Tamarind Seeds by KOH Activation for Fe(III) Adsorption from Aqueous Solution
Published 2015-01-01“…Proximate analysis, percent yield, iodine number, methylene blue number, and preliminary test of Fe(III) adsorption were also studied. …”
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