Proteomics and integrative omic approaches for understanding host–pathogen interactions and infectious diseases by Pierre M Jean Beltran, Joel D Federspiel, Xinlei Sheng, Ileana M Cristea

“…Further expanding the understanding of proteome organization during an infection, we discuss methods that characterize the regulation of host and pathogen proteomes through alterations in protein abundance, localization, and post‐translational modifications. …”
Get full text

Bacteriophages as Potential Anti-Pathogenic Agents for Intestinal Health of Weaned Piglets in the Post-Antibiotic Era: An Updated Review by Jun Chen, Jiajun Han, Zheng Yang, Wenyue Zhou, Yuyong He, Xingping Chen, Xin Li, Tiande Zou, Jinming You

Get full text

The type of pathogen is associated with organ failure and legacy dysfunction in patients with sepsis by Qinfen Gao, Zengzheng Li, Zengzheng Li, Zengzheng Li, Zengzheng Li, Jiawei Geng, Bin Han, Tonghua Yang, Shuai Feng, Shuai Feng, Shuai Feng, Shuai Feng, Lijuan Zhao, Yajun Teng, Yafei Li, Renbin Zhao, Renbin Zhao, Renbin Zhao, Renbin Zhao, Wei Zhang, Yi Wang, Yajie Wang, Yajie Wang, Yajie Wang, Yajie Wang

Get full text

Integrated genome and transcriptome analysis reveals pathogenic mechanisms of Calonectria eucalypti in Eucalyptus leaf blight by QianLi Liu, GuoQing Li, YuHua Liang, Yan Lin, KaiDong Liu, ZhenChi Huang, ShanNi Cao, FeiFei Liu

“…Moreover, most SMGCs were located in transposable element (TE)-rich regions, supporting a “two-speed” genome architecture that may facilitates adaptive evolution and pathogenic innovation. Conclusions This study provides the first integrative genome and infection-stage transcriptome map of C. eucalypti, revealing a coordinated, stage-specific deployment of pathogenicity-related gene clusters. …”
Get full text

Potassium silicate in the management of anthracnose in post-harvest bananas by Thaylla Caproni Ribeiro, Lucas Campos Dozza, Wesley Felipe Correia, Natália Moreira Mafra, Dalilla Carvalho Rezende

Get full text

Fungi-Kcr: a language model for predicting lysine crotonylation in pathogenic fungal proteins by Yong-Zi Chen, Yong-Zi Chen, Xiaofeng Wang, Zhuo-Zhi Wang, Haixin Li, Haixin Li

“…IntroductionLysine crotonylation (Kcr) is an important post-translational modification (PTM) of proteins, playing a key role in regulating various biological processes in pathogenic fungi. …”
Get full text

A novel post-mortem pathogen discovery program detects an outbreak of Echovirus E7: Uganda, 2022–2023 by Sonja L. Weiss, Sonja L. Weiss, Nicholas Bbosa, Nicholas Bbosa, Nicholas Bbosa, Gregory S. Orf, Gregory S. Orf, Michael G. Berg, Michael G. Berg, Deogratius Ssemwanga, Deogratius Ssemwanga, Sam Kalungi, Sam Kalungi, Stephen Balinandi, Maximillian Mata, Maximillian Mata, Henry Kyobe Bosa, Henry Kyobe Bosa, Henry Kyobe Bosa, Stella E. Nabirye, Joshua Buule, Tom Lutalo, Angela Havron, Angela Havron, Robert Downing, Mary A. Rodgers, Mary A. Rodgers, Francisco Averhoff, Francisco Averhoff, Gavin A. Cloherty, Gavin A. Cloherty, Pontiano Kaleebu, Pontiano Kaleebu

“…An epidemiologic assessment indicated that most identified pathogens were acquired via direct and/or indirect contact (e.g., fecal-oral, fomites) and that other modes of transmission (e.g., food-borne, insect-vectored) played a less significant role.ConclusionIntegration of mortuary surveillance, coupled with mNGS, into public health systems represents a powerful strategy for identifying unrecognized outbreaks and monitoring the (re-) emergence of infectious diseases.…”
Get full text

A Review on Recent Trends in Bacteriophages for Post-Harvest Food Decontamination by Márcia Braz, Carla Pereira, Carmen S. R. Freire, Adelaide Almeida

“…This review stands out by providing an overview of post-harvest food decontamination methods against some of the most important bacterial foodborne pathogens, with particular focus on the advantages and challenges of using phages, including their most recent post-harvest applications directly to food and integration into active food packaging systems, highlighting their potential in providing safer and healthier food products. …”
Get full text

Post-pandemic surveillance of SARS-CoV-2 in wastewater bodies using integrated molecular analysis by Gayatri Gogoi, Rashmi Rani Boro, Sarangthem Dinamani Singh, Emon Kalyan, Akib Ali, Keshab Nath, Hridoy Jyoti Mahanta, Pankaj Bharali

Get full text

Updating global estimates of pathogen-attributable diarrhoeal disease burden: a methodology and integrated protocol for a broad-scope systematic review of a syndrome with diverse i... by Margaret N Kosek, Brecht Devleesschauwer, Shannon E Majowicz, Josh M Colston, Thomas G Flynn, Andrea H Denton, Francesca Schiaffino, Carlotta Di Bari, Yuki Minato

“…Therefore, we developed this integrated systematic review methodology and protocol that aims to compile a database of published prevalence estimates for 17 diarrhoea-causing pathogens as inputs for disease burden estimation.Methods and analysis We will seek estimates of the prevalence of each endemic enteric pathogen estimated from published population-based studies that diagnosed their presence in stool samples from both asymptomatic subjects and those experiencing diarrhoea. …”
Get full text

MAP kinase gene STK1 is required for hyphal, conidial, and appressorial development, toxin biosynthesis, pathogenicity, and hypertonic stress response in the plant pathogenic fungu... by Po LI, Xiao-dong GONG, Hui JIA, Yong-shan FAN, Yun-feng ZHANG, Zhi-yan CAO, Zhi-min HAO, Jian-min HAN, Shou-qin GU, Jin-gao DONG

Get full text

Integrating Nanopore MinION Sequencing into National Animal Health AMR Surveillance Programs: An Indonesian Pilot Study of Chicken Slaughterhouse Effluent and Rivers by Rallya Telussa, Puji Rahayu, Thufeil Yunindika, Curtis J. Kapsak, Kanti Puji Rahayu, Oli Susanti, Imron Suandy, Nuraini Triwijayanti, Aji B. Niasono, Syamsul Ma’arif, Hendra Wibawa, Lestari Lestari, Gunawan B. Utomo, Farida C. Zenal, Luuk Schoonman, Lee E. Voth-Gaeddert

Get full text

Pathogenicity and virulence of Aeromonas schubertii in farmed Asian seabass (Lates calcarifer) in Thailand by Clara Trullàs, Sirikorn Kitiyodom, Komkiew Pinpimai, Putita Chokmangmeepisarn, Manoj Tukaram Kamble, Channarong Rodkhum, Nopadon Pirarat

“…Conclusions This study reports the presence of A. schubertii in Asian seabass and its association with significant mortality during a natural outbreak. The integration of experimental infection data, histopathology, and immunohistochemistry contributes to a comprehensive understanding of its pathogenicity and supports the development of effective control measures. …”
Get full text

A novel small RNA is important for biofilm formation and pathogenicity in Pseudomonas aeruginosa. by Patrick K Taylor, Antonius T M Van Kessel, Antonio Colavita, Robert E W Hancock, Thien-Fah Mah

“…The regulation of biofilm development requires multiple mechanisms and pathways, but it is not fully understood how these are integrated. Small RNA post-transcriptional regulators are a strong candidate as a regulatory mechanism of biofilm formation. …”
Get full text

Predominant Pathogens in Sternal Wound Infections Following Cardiac Surgery: A Systematic Review by Netty Suharty, Muhammad Riendra, Aulia Rahman, Heka Widya Putri, Ardiansyah Ardiansyah

“…Data from studies that met the criteria were evaluated to assess the microbes involved in post-cardiac surgery sternal wound infection. …”
Get full text

The role of epigenetics in plant pathogens interactions under the changing environments: A systematic review by Wenhao Wu, Guoqiang Fan

“…Small RNAs (miRNAs) and long non-coding RNAs (lncRNAs) act as post-transcriptional regulators, orchestrating immune signaling and pathogen counter-defense strategies. …”
Get full text

Rice Grain Storage Reduces Antibiotic Resistance Risks and Pathogens Through Enrichment of Antimicrobial Metabolites by Fang Wu, Yuanpeng Zhang, Peng Huang, Li Li, Yanguang Zhu, Quanxin Rao, Ruizhang Feng, Jie Tu

“…Multiple correlation analyses confirmed the significant reduction of ARGs and pathogens during storage. Integrated transcriptomic and metabolomic analyses identified genes and metabolites with persistent differential expression over the storage period. …”
Get full text

Characterization of multispecies microbial communities at beef and pork processing plants and their impact on pathogen stress tolerance by Rong Wang, Sapna Chitlapilly Dass, Vignesh Palanisamy, You Zhou, Tatum Katz, Joseph M. Bosilevac

“…However, overall higher survival and post-sanitization recovery of pathogen cells were observed in the treated pork plant samples than those in the beef plant samples. …”
Get full text

Targeting epigenetic regulators to overcome drug resistance in the emerging human fungal pathogen Candida auris by Yuping Zhang, Lingbing Zeng, Xinhua Huang, Yuanyuan Wang, Guangsheng Chen, Munika Moses, Yun Zou, Sichu Xiong, Wenwen Xue, Yanmei Dong, Yueru Tian, Ming Guan, Lingfei Hu, Zhe Yin, Dongsheng Zhou, Xiaotian Huang, Changbin Chen

“…Here, we systematically evaluate the role of histone H3 post-translational modifications in C. auris drug resistance, focusing on acetylation mediated by Gcn5 and Rtt109, and methylation mediated by Set1, Set2, and Dot1. …”
Get full text

Core features and inherent diversity of post-acute infection syndromes by Alain Trautmann

“…Post-acute infection syndromes (PAIS), i.e., long-lasting pathologies subsequent to infections that do not properly resolve, have both a common core and a broad diversity of manifestations. …”
Get full text