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341
Lipid-Polymer Hybrid Nanoparticles as a Smart Drug Delivery System for Peptide/Protein Delivery
Published 2025-06-01“…The efficient oral delivery of therapeutic proteins and peptides poses a tremendous challenge due to their inherent instability, large molecular size, and susceptibility to enzymatic degradation. …”
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342
Self-locking Fe-based shape memory couplers: Insights into SME and interface contact mechanics
Published 2025-08-01“…The obtained results highlight the complex interaction between post-processing and structural parameters, shedding light on the design and implementation of Fe-SMA coupling components with enhanced SME performance.…”
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343
THE STRATEGY OF FORMATION OF THE CONTENT OF TEACHING A FOREIGN LANGUAGE AS A REFLECTION OF SOCIO-CULTURAL DETERMINANTS OF MODERN SOCIETY
Published 2022-03-01“…In this regard, the article examines the European competencies and attempts to analyze the structural and content parameters of the competence-based paradigm of teaching in the Russian and European systems. …”
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344
Review of flow instability in gas-turbine compression system
Published 2025-06-01“…Compressor instability, particularly stall and surge, poses significant challenges to the performance, efficiency, and reliability of axial compressors in aerospace and power-generation systems. …”
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345
An Experimental Study on Strength and Durability for Utilization of Fly Ash in Concrete Mix
Published 2014-01-01“…As a case study the soil samples, received from Siirt Province areas which contain high sulfate rate, have been compared with respect to sulfate standard parameters of TS 12457-4. In such regions contact of underground water seep into hardened concrete substructures poses a risk of concrete deterioration. …”
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346
Revisiting sylvian fissure dissection - A preliminary investigation into surgical process modelling for evaluating surgical proficiency
Published 2025-01-01“…Surgeons' actions, workflow parameters, and adverse events during Sylvian fissure dissection were catalogued into Surgical Process Models (SPMs). …”
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347
Creep Behavior and Long-Term Deformation Prediction of Ground Reinforced by High-Permeability Grouting
Published 2025-01-01“…This phenomenon may lead to gradual surface settlement and structural instability, thereby compromising the long-term safety and performance of underground infrastructure. …”
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348
CONSIDERATIONS REGARDING DEFECTS THAT MAY OCCUR DURING FSP/SFSP PROCESSING OF ALUMINUM ALLOYS
Published 2025-09-01“…The review further delineates material-specific responses to FSP/SFSP and highlights the challenges posed by initial microstructural inhomogeneities and compositional variations. …”
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349
Deep Reinforcement Learning-Based Motion Control Optimization for Defect Detection System
Published 2025-04-01“…The X-ray defect detection system for weld seams in deep-sea manned spherical shells is nonlinear and complex, posing challenges such as motor parameter variations, external disturbances, coupling effects, and high-precision dual-motor coordination requirements. …”
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350
Entanglement microscopy and tomography in many-body systems
Published 2025-01-01“…Abstract Quantum entanglement uncovers the essential principles of quantum matter, yet determining its structure in realistic many-body systems poses significant challenges. …”
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351
Data-driven and physics-constrained acoustic holography based on optimizer unrolling
Published 2025-01-01“…NAH obtains images of structural vibrations to analyze the underlying acoustic phenomena. …”
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352
Surface subsidence induced by salt cavern gas storage and its impact on railway safety: Numerical simulation and fuzzy evaluation
Published 2025-06-01“…We propose a safety assessment framework based on the Analytic Hierarchy Process (AHP), which takes into account various factors, including cavern subsidence, train operation parameters (axle load, speed), subgrade conditions (lithology, fill characteristics), and subgrade protection measures (e.g., retaining structures and slope stabilization). …”
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353
Accumulation Differences in Perfluorooctanoic Acid and Its Ether Carboxylic Acid Alternatives in the Manila Clam (Ruditapes philippinarum)
Published 2025-04-01“…PFOA is widespread in aquatic environments and has attracted global attention due to the serious ecological risks it poses. Consequently, several countries and organizations have implemented strict restrictions or controls on its use. …”
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354
Prediction of Liquefaction-Induced Lateral Displacements Using Hybrid GBRT and EOA
Published 2026-01-01“…Liquefaction-induced lateral displacements (LILD) poses a significant challenge in geotechnical engineering due to its potential to cause extensive structural damage and ground instability. …”
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355
Assessing the Feasibility of Integrating a Thermal Separational Method with PV Recycling Technologies
Published 2025-03-01“…The applied heating parameters enabled the cells to be removed from the PV panels without structural damage. …”
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356
Mechanical Tensile Response of Ni–Graphene Nanocomposites in Hydrogen-Irradiation-Coupled Environments Using Molecular Dynamics Simulations
Published 2025-06-01“…In Gen-IV nuclear reactors, structural materials must endure unprecedented levels of neutron irradiation and hydrogen exposure, posing significant challenges for traditional Ni-based alloys. …”
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357
Position of SGLT2i in prediabetes: A systematic review of literature
Published 2025-04-01“…This condition, often preceding Type 2 diabetes mellitus (T2DM), poses elevated risks for cardiovascular and renal complications. …”
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358
Use of Artemisinin- Combination Therapies in Port Harcourt
Published 2013-07-01“…A survey was conducted with the aid of structured questionnaires in Port Harcourt metropolis. …”
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359
Catalytic Ammonia Combustion: Legacy Catalytic Burner Designs and Catalyst Requirements for In Situ Hydrogen Production
Published 2025-07-01“…However, its direct utilisation in combustion systems poses significant challenges, including low flame speed, high ignition temperature, and the formation of nitrogen oxides (NO<sub>X</sub>). …”
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360
A Qualitative Study of Researchers Perspective on the Use and Risks of Open Government Data
Published 2025-06-01“…However, this openness also poses various opportunities for losses or even risks, especially related to low data quality, personal data security issues, data translation errors, and misuse of information. …”
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