Integrating spatial mapping and metabolomics: A novel platform for bioactive compound discovery and saline land reclamation by Tushar Andriyas, Nisa Leksungnoen, Pichaya Pongchaidacha, Arashaporn Uthairangsee, Suwimon Uthairatsamee, Peerapat Doomnil, Yongkriat Ku-Or, Chatchai Ngernsaengsaruay, Sanyogita Andriyas, Arerut Yarnvudhi, Rossarin Tansawat

“…Saline lands pose significant environmental and agricultural challenges due to high soil salinity, which disrupts water uptake and ionic balances, limiting conventional crop productivity. …”
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Optimization design of an acoustic cover layer for a cylindrical cavity based on porous materials by Bohan ZHANG, Jili RONG, Xiuyan CHENG

“…During the launch and flight of carrier rockets, the acoustic and vibrational excitations generated by the external environment pose significant threats to their internal payloads. …”
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Potential therapeutic effects of IL28RA inhibition on acute myocardial infarction through phosphorylated JAK1/STAT1 signaling pathways by Ge Gong, Xiangxuan Chen, Xinghu Zhang, Jian Yin, Wenhui Wan

“…Abstract While current coronary intervention therapies and surgical bypass procedures are widely utilized, the treatment of acute myocardial infarction (AMI) in the elderly continues to pose significant challenges. Following AMI, the body’s immune system is activated, resulting in the release of inflammatory mediators that exacerbate myocardial damage. …”
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Effects of dendritic segregation and local internal stress on microstructure evolution in a 3rd-generation single crystal superalloy during thermal exposure by Yabo Liu, Yang Li, Zhiran Yan, Donghai Yu, Chenlong Liang, Ming Xue, Changjian Geng, Ru Su, Shilei Li, Lunhua He, Yan-dong Wang

“…The inevitable dendritic segregations in single crystal superalloys pose a serious challenge to the microstructural stability and mechanical reliability. …”
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Height Propagation Law and Controlling Strategies of Acid Fractures in Carbonate Gas Reservoirs With Bottom Water Layer Under Different Stress Profiles by Jian Yang, Weihua Chen, Zixi Jiao, Jiexiao Ye, Song Li, Qiuyun Hu, Haiyan Zhu, Zhaopeng Zhang

“…However, improper acid-fracturing operational parameters pose a risk of fracture communication with the bottom water layer, leading to increased water production and a significant decline in gas productivity. …”
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Dispersion Modeling of Odor Emissions from Area Sources in a Municipal Wastewater Treatment Plant by Cristian Constantin, Cristina Modrogan, Annette Madelene Dancila, Georgeta Olguta Gavrila, Simona Mariana Calinescu, Alexandru Cirstea, Valeriu Danciulescu, Gheorghita Tanase, Gabriela Geanina Vasile

“…Wastewater treatment plants (WWTPs) generate significant emissions of gaseous substances, such as H₂S, NH₃, and VOCs, which cause discomfort and pose health risks to residents in surrounding areas. …”
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Influence of wetted perimeters variation of physical cover porosity on the evaporation suppression effect of plains reservoirs in arid zones by Shaolei Wang, Kebin Shi, Kewu Han, Xueying Zhou, Xinjun Yan

“…Study region: In arid and semi-arid regions, high evaporation losses from plains reservoirs pose a significant challenge to the effective management of water resources. …”
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Characteristics and Efficacy of Warfarin Sodium Tablet Subdivided by 3D Printing Technology: A Retrospective Cohort Study of Patients After Prosthetic Valve Replacement by Lv J, Fu K, Xiong L, Chen B, Zhan L, Liu J, Lin Z, Yang F, Chen J

“…Jieqiong Lv,1 Kaixia Fu,2 Lingjuan Xiong,3 Bishan Chen,4 Luchuan Zhan,3 Jiang Liu,3 Zhanyi Lin,5 Fan Yang,2,4 Jisheng Chen4 1Department of Pharmacy, The Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, People’s Republic of China; 2Guangdong Provincial Key Laboratory of Advanced Drug Delivery Systems and Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Teaching Laboratory Center, Guangdong Pharmaceutical University, Guangzhou, Guangdong, People’s Republic of China; 3Department of Pharmacy, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 4Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, Guangdong, People’s Republic of China; 5Guangdong Geriatric Institute, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, People’s Republic of ChinaCorrespondence: Fan Yang, Email gzyangfan@hotmail.com Jisheng Chen, Email cjslym@163.comBackground: Due to the individual-level clinical variation in dosing requirements in commercially available drugs, attaining the objective of clinical individualization and precise drug administration continues to pose a global challenge. Currently, the optimal approach for preparing personalized and precise medications within the clinical setting is unknown.Aim: This study aimed to explore the effectiveness, safety and satisfaction of three-dimensional (3D) printing technology as a novel subdivision method in providing precise warfarin sodium (WFS) subdivided tablets for patients after prosthetic valve replacement (PVR).Methods: The optimal formulation, preparation process, parameters, and the relationship between dose and the printing volume were investigated, and the quality of the six specifications of WFS 3D-printed subdivided and pharmacist-split tablets was studied. …”
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Rapid Fine-Grained Damage Assessment of Buildings on a Large Scale: A Case Study of the February 2023 Earthquake in Turkey by Zhonghua Hong, Hongyang Zhang, Xiaohua Tong, Shijie Liu, Ruyan Zhou, Haiyan Pan, Yun Zhang, Yanling Han, Jing Wang, Shuhu Yang

“…However, the time-consuming process of three-dimensional (3-D) reconstruction, inadequate vertical accuracy of digital surface model (DSM), and concentrated clustering of buildings pose challenges for collapse assessment focused on buildings. …”
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Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis by Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui

“…However, their extensive use, accumulation, and biomagnification pose significant risks to humans. Increasing evidence has suggested that NEOs may affect glucose homeostasis, but little research has linked NEOs exposure to gestational diabetes mellitus (GDM), which is the most common disease in pregnancy. …”
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An optimization based framework for water quality assessment and pollution source apportionment employing GIS and machine learning techniques for smart surface water governance by Abhijeet Das

“…Abstract Spatial evaluation of the region is associated with the assessment of the quality of water. Dump sites pose a significant threat to surface water resources due to the possibility of leachate contamination. …”
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Visualization of coronary artery calcification and its impact on percutaneous coronary intervention procedure (a literature review) by V. O. Hubka, Yu. M. Vailo, A. M. Materukhin, A. L. Makarenkov

“… In general, the phenomenon of vascular calcification is quite common and might pose considerable impediments for vascular, cardiovascular and endovascular surgeons, as well as for interventional cardiologists when performing surgical manipulations during the treatment of patients with coronary artery disease (CAD) or peripheral atherosclerosis. …”
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Seasonal Characterization of the Aerobiome in Hematopoietic Stem Cell Transplant Rooms: Potential Risk for Immunosuppressed Patients by Emilio Mariano Durán-Manuel, Edgar Fiscal-Baxin, Andres Emmanuel Nolasco-Rojas, Miguel Ángel Loyola-Cruz, Clemente Cruz-Cruz, Marianela Paredes-Mendoza, Adolfo López-Ornelas, Dulce Milagros Razo Blanco-Hernández, Nayeli Goreti Nieto-Velázquez, Aída Verónica Rodríguez-Tovar, Adrián Ramírez-Granillo, Enzo Vásquez-Jiménez, Verónica Fernández-Sánchez, Erika Gómez-Zamora, Mónica Alethia Cureño-Díaz, Andrea Milán-Salvatierra, Carlos Alberto Jiménez-Zamarripa, Claudia Camelia Calzada-Mendoza, Juan Manuel Bello-López

“…Infections pose a risk for patients undergoing hematopoietic stem cell (HSC) transplants due to their immunosuppression, making them susceptible to opportunistic infections. …”
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HiGoReg: A Hierarchical Grouping Strategy for Point Cloud Registration by Tengfei Zhou, Jianxiang Gu, Zhen Dong

“…This method incrementally updates the pose of the source point cloud via a hierarchical mechanism, while adopting a grouping strategy to efficiently conduct recursive parameter estimation. …”
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A scaling law to model the effectiveness of identification techniques by Luc Rocher, Julien M. Hendrickx, Yves-Alexandre de Montjoye

“…However, quantifying their effectiveness at scale and, by extension, the risks they pose remains a significant challenge. Here, we propose a two-parameter Bayesian model for exact matching techniques and derive an analytical expression for correctness (κ), the fraction of people accurately identified in a population. …”
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ANALYSIS OF PROBLEMS OF IMPLEMENTATION OF THE PRIORITY DIRECTION OF «PERSONALIZED MEDICINE» IN THE FORMAT OF FULL PROJECT CYCLE by A. N. Petrov, N. G. Kurakova, I. M. Son

“…To minimize and manage a wide range of risks and barriers, that pose a threat to the implementation of all phases of such projects, a multi-parameter expertise is needed, along with an analysis of the trends in the development of a new technology direction, an assessment of economic feasibility, personnel and infrastructure support, adequacy of legal regulation.…”
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Numerical study on the influence of flexible net permeability on debris flow impact loads. by Yanfen Wang, Siyu Xiao, Linbo Qiao

“…Debris flows in mountainous regions pose a significant threat to human lives and property. …”
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Forecasting the Timing of Peak Solar Flare Index in Solar Cycle 25 for Improved Space Weather Prediction by Mu He, Hongbing Zhu

“…Solar flares, driven by magnetic reconnection on the Sun, pose substantial threats to Earth’s technological infrastructure. …”
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The Potential Proallergenic Activity of Tranzschelia pruni-spinosae and Phragmidium rubi-idaei in vitro Studies by Sztandera-Tymoczek M, Wdowiak-Wróbel S, Świderska U, Palusińska-Szysz M, Szuster-Ciesielska A

“…Furthermore, these fungi pose a potential health risk to humans, as they are major sources of allergens. …”
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Bioremediation of malachite green dye using Sargassum wightii seaweed and its biological and physicochemical characterization by Kaliaperumal Kumaravel, Aboobacker Janeeba, Dhanapal Vigneshpriya, Gayathri Abinaya, Subramanian Kumaran, Suresh Arumugam, Elumalai Sanniyasi, Sampath Shobana, Devanesan Sandhanasamy, AlSalhi Mohamad S., Asaithambi Perumal

“…Textile dye effluents and their contamination in aquatic environments is a serious risk pose of aquatic pollution. Degradation of such dyes using a biological treatment like microbe and plant-based remediation is an eco-friendly approach and more feasible than the physical and chemical treatment processes. …”
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