Groundwater for drinking and sustainable agriculture and public health hazards of nitrate: Developmental and sustainability implications for an arid aquifer system by Boualem Bouselsal, Adel Satouh, Johnbosco C. Egbueri, Mofreh A. Hashim, Ahmed A. Arafat, Prabhu Paramasivam, Ali Alzaed, Enas E. Hussein

“…A total of 44 groundwater samples were analyzed for physicochemical parameters, including pH, major ions (Ca2+, K+, Na+, Mg2+, SO42−, Cl−, NO3−, HCO3−) total dissolved solids (TDS), and electrical conductivity (EC). …”
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Transcriptome and metabolome analysis of senescent rice (Oryza sativa L.) seeds: insights into the mechanism of germination vigor and seedling morphogenesis by Jingxin Huo, Dianfeng Zheng, Naijie Feng, Rui Zhang, Yingbin Xue, Aaqil Khan, Hang Zhou, Xuefeng Shen, Liming Zhao, Yifei Li, Xiaojun Liu, Junjie Liu, Jiayi Li, Wanqi Mei, Xiaole Du, Yanan Feng

“…The seed aging phenomenon that occurs during storage poses a significant challenge to crop production, as it can lead to reduced germination rates and impaired seed vitality. …”
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The approach to placement of a continuous-flow intracorporeal ventricular assist device in small left ventricle by Ryaan EL-Andari, MD, Josiane Dion, MD, Jennifer Conway, MD, MSc, Tara Pidborochynski, MSc, Lindsey Carter, MD, Gurmeet Singh, MD, MSc, Roderick MacArthur, MD, MSc, Steven Meyer, MD, PhD, Devilliers Jonker, MD, Darren H. Freed, MD, PhD, Holger Buchholz, MD

“…One limitation of the HM3 is its large size, which poses a challenge for implantation in smaller LVs. …”
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Differentiated fatty acid allocation of Daphnia magna helped to maintain their population under food quality deterioration by Sirui Wang, Zhengwen Liu, Zhengwen Liu, Xiaoqi Su, Xiaotong Jin, Hui Jin, Yaling Su, Jianjun Wang, Erik Jeppesen, Erik Jeppesen, Erik Jeppesen, Erik Jeppesen, Erik Jeppesen, Xiufeng Zhang, Yali Tang

“…However, cyanobacteria blooms frequently lead to PUFA deficiencies, which poses a substantial challenge to population fitness. …”
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Physicochemical Exploration and Computational Analysis of Bone After Subchronic Exposure to Kalach 360 SL in Female <i>Wistar</i> Rats by Latifa Hamdaoui, Hafedh El Feki, Marwa Ben Amor, Hassane Oudadesse, Riadh Badraoui, Naila Khalil, Faten Brahmi, Saoussen Jilani, Bandar Aloufi, Ibtissem Ben Amara, Tarek Rebai

“…Due to its broad-spectrum activity, glyphosate serves as the main active ingredient in various commercial herbicide formulations, including Roundup and Kalach 360 SL (KL). It poses a health hazard to animals and humans due to its persistence in soil, water erosion, and crops. …”
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Superparamagnetic Micelles for the Magnetic Hyperthermia Against Glioblastoma: A Multiphysics Approach for Personalized Treatment Planning by Matteo Bruno Lodi, Eleonora Matilde Angela Corda, Wirat Assawapanumat, Gian Luca Chabert, Francesco Desogus, Luca Saba, Andrea Perra, Norased Nasongkla, Alessandro Fanti, Giuseppe Mazzarella

“…The treatment of diffuse, high-grade gliomas, the most aggressive form of primary brain tumors, poses significant therapeutic challenges. Recurrent high-grade gliomas are associated with a median overall survival of less than one year; therefore, new therapeutic strategies must be sought. …”
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Optimized Extraction Method for Neutral Cannabinoids Quantification Using UHPLC-HRMS/MS by João Victor Meirelles, Débora Cristina Diniz Estevam, Vanessa Farelo dos Santos, Henrique Marcelo Gualberto Pereira, Tatiana D. Saint Pierre, Valdir F. Veiga-Junior, Monica Costa Padilha

“…The medical potential of these formulations is mainly attributed to neutral cannabinoids, such as cannabidiol (CBD), tetrahydrocannabinol (THC), and cannabinol (CBN), and their non-standardized content poses a significant fragility in these pharmaceutical inputs. …”
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Macular Telangiectasia Type 2: Long-Term Disease Progression and Management of Complications by Merve Özbek, Özgür Artunay, Rümeysa Koçak, İlker Hoşver, Metehan Şimşek

“…MH development, though rare, poses a significant challenge, with variable surgical outcomes.…”
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Performance assessment of sustainable cooling strategies in canarian Greenhouses: Evaluating earth-to-air heat exchanger and rock-bed systems by Fatima Ezzahra Allali, Hicham Fatnassi, Hassan Demrati, Ahmed Wifaya, Ahmed Aharoune

“…However, maintaining optimal microclimatic conditions for crop growth during the summer months poses significant challenges. These conditions often require intensive cooling, which is typically reliant on fossil fuel-based energy sources. …”
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Sustainable nanophytosome-based therapies against multidrug-resistant Escherichia coli in urinary tract infections: an in Vitro and in vivo study by Ming Ming Wen, Ibrahim A. Abdelwahab, Rania Abozahra, Sarah M. Abdelhamid, Kholoud Baraka, Heba Essam Sedky Ahmed, Wessam F. El-Hadidy

“…The rise in multidrug-resistant (MDR) E. coli strains as the predominant cause of UTIs presents a substantial public health concern and poses a challenge to existing antibiotic treatments. …”
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PO27 | B-cell lymphoproliferative disorder and acquired coagulopathy: an insidious link

“…At the admission, coagulation studies confirmed markedly abnormal coagulation parameters: PT/INR 5.36 and aPTT 1.56. The mixing test showed suboptimal correction. …”
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Assessment of seed rate and weed management practice on weed control, crop productivity and profitability of dry direct-seeded rice by V.K. Choudhary, M.P. Sahu, R.P. Dubey, Rajbir Singh, J.S. Mishra

“…However, heavy weed infestation poses a major limitation, significantly reducing yields. …”
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Integrated microbiome and metabolome analysis reveals altered gut microbial communities and metabolite profiles in dairy cows with subclinical mastitis by Jie Yu, Chenhui Liu, Dingfa Wang, Pingmin Wan, Lei Cheng, Xianghua Yan

“…Abstract Background Dairy cow mastitis is a common and prevalent disease arose by various complicated pathogeny, which poses serious threat to the health of cows, safety of dairy product and economic benefits for pastures. …”
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Physicochemical Properties and Microalgal Diversity of Sabon Gari and Rimaye Fish Ponds, Nasarawa State, Nigeria by Sadiya Awala Samuel, Rabiu, A. S., Yisa, A. G., Osegbo, A. N., Omada, S.

“…The physicochemical analysis revealed significant differences between the ponds in parameters such as pH, dissolved oxygen, biological oxygen demand, chemical oxygen demand, turbidity, water hardness, and chloride ions. …”
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Study on sodium emissions during the combustion of blends of biomass and high-ash content coal in an oxyfuel environment by Sachin K. S, R.V. Ravikrishna, Pratikash Panda

“…However, emissions of alkali metals, chlorine, and sulfur-based gases during biomass combustion poses serious challenges in terms of the operability of power plants. …”
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Evaluating the impact of the Modifiable Areal Unit Problem on ecological model inference: A case study of COVID-19 data in Queensland, Australia by Shovanur Haque, Aiden Price, Kerrie Mengersen, Wenbiao Hu

“…However, the Modifiable Areal Unit Problem (MAUP) poses challenges in disease modelling by impacting the reliability of statistical inferences drawn from spatially aggregated data. …”
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The Effect of Hydrogen Peroxide on Biogas and Methane Produced from Batch Mesophilic Anaerobic Digestion of Spent Coffee Grounds by Siham Sayoud, Kerroum Derbal, Antonio Panico, Ludovico Pontoni, Massimiliano Fabbricino, Francesco Pirozzi, Abderrezzaq Benalia

“…AD of SCG, while promising, is hindered by its complex lignocellulosic structure, which poses a significant challenge. This study investigates the efficacy of hydrogen peroxide (H₂O₂) pretreatment in addressing this issue, with a particular focus on enhancing biogas and methane production. …”
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Cost-effectiveness of susceptibility-guided therapy under varying rates of clarithromycin resistance by Shihan Xu, Xianzhu Zhou, Yiqi Du

“…Furazolidone quadruple therapy is employed as the second-line regimen in SGT group. Model parameters are derived from previous literature and China Medical Insurance. …”
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Population pharmacokinetic study of colistin for dose optimization in patients with acute on chronic liver failure (ACLF) patients by Dr Ritika Bhandari, Prof. Nusrat Shafiq, Dr. Naveen Murali, Dr. Soumya Vij, Dr. Nipun Verma, Dr. Avaneesh Kumar Pandey, Prof. Vikram Prakash Gota, Dr. M Surulivel Rajan, Prof. Ajay Kumar Duseja, Prof. Samir Malhotra

“…Introduction: Acute on chronic liver failure (ACLF) is characterized by severe systemic inflammation and multiple organ failures, posing high mortality risks, particularly in cirrhotic patients. …”
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CONTEXTUAL APPROACHTOTEACHINGTHE ELECTIVEDISCIPLINE “THEORYOF MASS COMMUNICATION” TO BACHELORS OF PEDAGOGICAL UNIVERSITIES (SPECIALITIES “GEOGRAPHY” AND “MUSICAL ART”) by Duboviy Zakhar, Lakomova Olena

“…In the research, methods of content analysis, specification, problem-posing, as well as task-based and contextual approaches were used. …”
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