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Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines
Published 2025-01-01“…Continued use of these vaccines, however, threatens ultimate disease eradication and achievement of a polio-free world. Virus-like particles (VLPs) that lack a viral genome represent a safer potential vaccine, although they require particle stabilization. …”
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Advancing poliovirus eradication: lessons learned from piloting direct molecular detection of polioviruses in high-risk and priority geographies
Published 2025-02-01“…ABSTRACT In the Global Polio Laboratory Network (GPLN), poliovirus (PV) screening results from acute flaccid paralysis (AFP) surveillance is based on virus isolation (VI) through cell culture, entailing long turnaround times and the amplification of live poliovirus. …”
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La red de centros regionales de poliomielitis de la Organización Mundial de la Salud como estrategia contra esta enfermedad (1954-1963)
Published 2020-01-01“…La red contribuyó a transformar la lucha contra la polio al facilitar la circulación de conocimientos, personas y prácticas científico-asistenciales.…”
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Assessing the resilience of child immunisation programmes using geospatial modelling and interrupted time series analysis in Ethiopia and Kenya amidst the COVID-19 pandemic: tracki...
Published 2024-07-01“…Lockdowns and travel restrictions, coupled with fear of contracting the virus, disrupted services, especially for women’s and children’s health, derailing progress on sustainable development goals. …”
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