Barriers to and outcomes of unspecified kidney donation in the UK: BOUnD, a mixed-methods study by Nizam Mamode, Sam Norton, Paul McCrone, Joe Chilcot, Heather Draper, Peter Gogalniceanu, Mira Zuchowski, Lisa Burnapp, Jan Shorrock, Kiran Gupta, Hannah Maple

“…Results RQ1 Fifty-nine interviews were conducted with healthcare professionals at six United Kingdom centres. There was broad support for unspecified donation, but key themes included the need for further training and information, consistency in approach across the United Kingdom, and uncertainty about age limits and psychological assessments. …”
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Clinical and cost-effectiveness of detailed anomaly ultrasound screening in the first trimester: a mixed-methods study by Jehan N Karim, Helen Campbell, Pranav Pandya, Edward C F Wilson, Zarko Alfirevic, Trish Chudleigh, Elizabeth Duff, Jane Fisher, Hilary Goodman, Lisa Hinton, Christos Ioannou, Edmund Juszczak, Louise Linsell, Heather L Longworth, Kypros H Nicolaides, Anne Rhodes, Gordon Smith, Basky Thilaganathan, Jim Thornton, Gillian Yaz, Oliver Rivero-Arias, Aris T Papageorghiou

“…Background In the United Kingdom, pregnant women are offered two scans: at 11–14 and 18–20 weeks’ gestation. Current guidance supports fetal anatomical screening at the second scan, but evidence suggests earlier detection is possible. …”
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A process evaluation of the walking in ScHools (WISH) study using the RE-AIM framework by Angela Carlin, Leanne C. Doherty, S. Maria O’Kane, Russell Jago, Ian M. Lahart, Gary McDermott, Maria Faulkner, Alison M. Gallagher, Marie H. Murphy

“…Conclusions Despite a promising feasibility study and a comprehensive walk leader training programme, the extent to which the intervention was adopted and implemented varied, suggesting future school-based physical activity interventions need to consider individual school contexts to ensure intervention fidelity. …”
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Better public housing management in Ghana by Samson Aziabah

“…Also, the research found that, in general, performance in HM may be assessed by using indicators such as: quality of maintenance, responses from staff in relation to tenant services, and access to information by tenants, which measure effectiveness; cost of maintenance per dwelling and net rent as measures of efficiency and economy; application procedures, rent levels, and support for tenants as measures of equity; and the level of participation and the frequency and ease of communication with tenants as measures of legitimacy and support for HM. …”
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Within-laboratory SARS-CoV-2 real time PCR testing operations in Nepal: a simulation-based analysisResearch in context by Fannie L. Côté, Nadia Lahrichi, Erica Gralla, Hannah Bakker, Parvathy Krishnan Krishnakumari, Joaquim Gromicho, Arunkumar Govindakarnavar, Runa Jha, Lilee Shrestha, Nirajan Bhusal, Saugat Shrestha, Rashmi Mulmi, Priya Jha, Reuben Samuel, Dhamari Naidoo, Victor J. del Rio Vilas

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Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…Carers echoed the need for a supportive transition process. Several aspects of the ECHOMANTRA programme were welcomed, with the mixed patient/supporter online groups and online group facilitators experienced as particularly helpful. …”
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A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT by Nusrat Husain, Karina Lovell, Carolyn A Chew-Graham, Farah Lunat, Penny Bee, Matthias Pierce, Najia Atif, Saadia Aseem, Kamaldeep Bhui, Peter Bower, Traolach Brugha, Nasim Chaudhry, Akbar Ullah, Linda Davies, Nadeem Gire, Deepali Sharma, Jahanara Miah, Waqas Ahmed, Joe Kai, Ilyas Mirza, Jillian Morrison, Naeem Mohmed, Atif Rahman, Shanaya Rathod, Najma Siddiqi, Waquas Waheed, Christopher Williams, Nosheen Zaidi, Richard Emsley, Richard Morriss

“…The findings suggest improved emotional and social support and an enhanced sense of well-being. Economic evaluation Positive Health Programme implementation was estimated to cost an average of £408 per participant. …”
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Bringing malaria diagnosis and treatment closer to the people: economic rationale for expanding malaria community case management to all ages in a rural district in Madagascar by Walter Ochieng, Julie R. Gutman, Catherine Dentinger, Aina Harimanana, Judickaelle Irinantenaina, Hobisoa Léa Razanadranaivo, Oméga Raobela, Aline Mukerabirori, Laurent Kapesa, Andres Garchitorena, Laura Steinhardt

“…Incremental cost-effectiveness ratios (ICERs) per DALY averted ranged from -$21.86 to $212.42. …”
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Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis by Mamidipudi Thirumala Krishna, Yogini H Jani, Iestyn Williams, Ruben Mujica-Mota, Rebecca Bestwick, Michele Siciliano, Robert Michael West, Rashmeet Bhogal, Bee Yean Ng, Kornelija Kildonaviciute, Rachel Pollard, Nicola Jones, Louise Dunsmure, Mairead McErlean, Neil Powell, Chidanand C Hullur, Ariyur Balaji, Jonathan Sandoe, Amena Warner, Ron Daniels, Caroline Thomas, Siraj A Misbah, Louise Savic

“…While HCPs recognised complexities of the DPC, data also support the feasibility of delivery by non-allergy specialists with appropriate resources, training, facilities, local policies and governance framework and escalation or referral pathways to allergy specialists. …”
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Software with artificial intelligence-derived algorithms for detecting and analysing lung nodules in CT scans: systematic review and economic evaluation by Julia Geppert, Peter Auguste, Asra Asgharzadeh, Hesam Ghiasvand, Mubarak Patel, Anna Brown, Surangi Jayakody, Emma Helm, Dan Todkill, Jason Madan, Chris Stinton, Daniel Gallacher, Sian Taylor-Phillips, Yen-Fu Chen

“…Models estimated incremental cost-effectiveness ratios, cost per correct detection of an actionable nodule, and cost per cancer detected and treated. …”
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Clinical and cost-effectiveness of first contact physiotherapy for musculoskeletal disorders in primary care: the FRONTIER, mixed method realist evaluation by Nicola E Walsh, Alice Berry, Serena Halls, Rachel Thomas, Hannah Stott, Cathy Liddiard, Zoe Anchors, Fiona Cramp, Margaret E Cupples, Peter Williams, Heather Gage, Dan Jackson, Paula Kersten, Dave Foster, Justin Jagosh

“…As such, the case study evaluation was slightly underpowered, particularly in the GP arm, as services were capitalising on national funding programmes supporting the employment of FCPs in primary care, yet this work still provides significant insight into the clinical effectiveness and costs associated with the various models of care. …”
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Cervical ripening at home or in hospital during induction of labour: the CHOICE prospective cohort study, process evaluation and economic analysis by Mairead Black, Cassandra Yuill, Mairi Harkness, Sayem Ahmed, Linda Williams, Kathleen A Boyd, Maggie Reid, Amar Bhide, Neelam Heera, Jane Huddleston, Neena Modi, John Norrie, Dharmintra Pasupathy, Julia Sanders, Gordon C S Smith, Rosemary Townsend, Helen Cheyne, Christine McCourt, Sarah Stock

“…However, there was substantial uncertainty with the adjusted analysis consistent with a 74% decrease in the risk through to an 81% increase. qCHOICE Important aspects of service users’ experience of home cervical ripening were quality of information provided, support and perception of genuine choice. Economic analysis Home cervical ripening with balloon led to cost savings of £993 (−£1198, −£783) per woman and can be considered the dominant strategy. …”
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Morphine use in the last six days of life of patients with HIV/AIDS at the inpatient unit of a South African hospice implementing the ICHC model by R. Els, H.M. Power

“…This model requires that the hospice provide the overall management of the home-based care programme, as well as various forms of support. Care provision is shared between professional nurses and non-professional community-based caregivers, who are trained by Hospice. …”
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Clinical and cost-effectiveness of paramedics working in general practice: a mixed-methods realist evaluation by Matthew Booker, Sarah Voss, Nicky Harris, William Hollingworth, Nouf Jeynes, Hazel Taylor, Kirsty Garfield, Helen Baxter, Jonathan Benger, Andy Gibson, Trudy Goodenough, Justin Jagosh, Kim Kirby, Cathy Liddiard, Alyesha Proctor, Sarah Purdy, Behnaz Schofield, Hannah Stott, Grace Scrimgeour, Nicola Walsh

“…However, it is important that patients are supported to understand the paramedic working in general practice role. …”
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Evaluating the population impact of hepatitis C direct acting antiviral treatment as prevention for people who inject drugs (EPIToPe) – a natural experiment (protocol) by Jeremy Horwood, Andrew Radley, John F Dillon, Peter Vickerman, Rory N Gunson, Mary Ramsay, Chris Metcalfe, William Hollingworth, Hannah Fraser, Helen Harris, Ellen Heinsbroek, Lawrie Elliott, Paul Flowers, Sema Mandal, Matthew Hickman, David Goldberg, Natasha Martin, Emma Hamilton, Daniela De Angelis, Graham Foster, Peter Donnan, Ann Eriksen, Samreen Ijaz, David Liddell, Lewis J Z Beer, Kate Drysdale, Rachel Glass, Lesley Graham, Ross Harris, Vivian Hope, Sarah Karen Inglis, Hamish Innes, Athene Lane, Jade Meadows, Andrew McAuley, Stephanie Migchelsen, Alex Murray, Gareth Myring, Norah E Palmateer, Anne Presanis, Pantelis Samartsidis, Ruth Simmons, Katy Sinka, Gabriele Vojt, Zoe Ward, David Whiteley, Alan Yeung, Sharon J Hutchinson

“…We will present findings to practitioners and policymakers, and support design of an evaluation of HCV TasP in England.…”
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Species-specific machine learning models for UAV-based forest health monitoring: Revealing the importance of the BNDVI by Simon Ecke, Florian Stehr, Jan Dempewolf, Julian Frey, Hans-Joachim Klemmt, Thomas Seifert, Dirk Tiede

“…Furthermore, the averaged values per sample tree over three years, alongside the 5th and 25th percentile of the data distribution, have proven to be of key importance. …”
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Organising general practice for care homes: a multi-method study by Barbara Hanratty, Rachel Stocker, David Sinclair, Katie Brittain, Karen Spilsbury, Daniel Stow, Louise Robinson, Fiona E Matthews

“…Implementation of change Our findings support a considered approach to implementation of new initiatives. …”
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Glycaemic control in labour with diabetes: GILD, a scoping study by Nia Wyn Jones, Eleanor J Mitchell, Kate F Walker, Susan Ayers, Lucy Bradshaw, Georgina Constantinou, Tasso Gazis, Shalini Ojha, Phoebe Pallotti, Stavros Petrou, Rachel Plachcinski, Michael Rimmer, Liz Schroeder, Jim G Thornton, Natalie Wakefield

“…There was support for the trial, but participants outlined important aspects including the timing of approach and consent and ensuring a multidisciplinary approach to conducting the trial within the hospital. …”
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Variation within and between digital pathology and light microscopy for the diagnosis of histopathology slides: blinded crossover comparison study by David RJ Snead, Ayesha S Azam, Jenny Thirlwall, Peter Kimani, Louise Hiller, Adam Bickers, Clinton Boyd, David Boyle, David Clark, Ian Ellis, Kishore Gopalakrishnan, Mohammad Ilyas, Paul Kelly, Maurice Loughrey, Desley Neil, Emad Rakha, Ian SD Roberts, Shatrughan Sah, Maria Soares, YeeWah Tsang, Manuel Salto-Tellez, Helen Higgins, Donna Howe, Abigail Takyi, Yan Chen, Agnieszka Ignatowicz, Jason Madan, Henry Nwankwo, George Partridge, Janet Dunn

“…Providing adequately trained pathologists to serve the needs of these patients across the country is a major challenge, even more so to provide cover out of hours which is needed to support the care of renal transplant recipients in need of urgent assessment. …”
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