Azithromycin in the Management of Upper Respiratory Tract Infections (URTIs): Indian Real-Life Experience by Dominic M, Srivastava R, Shah K, Naik SM, Rout K, Ray B, Patil D, Rana D, Swami OC

“…Proportion of patients reporting sore throat was reduced from 95.8% to 10.4%; work absenteeism dropped from 47.9% to 1%; and fever subsided in 97.4% of patients. …”
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Radiologic assessment of the optimal point for tube thoracostomy using the sternum as a landmark: a computed tomography‐based analysis by Jaeik Jang, Jae-Hyug Woo, Mina Lee, Woo Sung Choi, Yong Su Lim, Jin Seong Cho, Jae Ho Jang, Jea Yeon Choi, Sung Youl Hyun

“…Results When virtual tube thoracostomy routes were drawn at the mid-axillary line at the 5th ICS level, 150 patients (81.5%) on the right side and 179 patients (97.3%) on the left did not pass the diaphragm. …”
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Intravitreal Clindamycin and Dexamethasone Combined with Systemic Oral Antitoxoplasma Therapy versus Intravitreal Therapy Alone in the Management of Toxoplasma Retinochoroiditis: A... by Ashraf Bor’i, Ashraf Mahrous, Mahmoud A. Al-Aswad, Haitham Y. Al-Nashar, Waled M. Nada, Mostafa Wagih, Ahmed M. B. Awad, Wael M. El-Haig

“…To compare clinical outcome of IVCD combined with oral therapy with IVCD alone in patients with toxoplasmic retinochoroiditis. Patients and Methods. …”
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Acute Portal Vein Thrombosis Treated with Recombinant Human Soluble Thrombomodulin Combined with Antithrombin III by Satoshi Nakayama, Naoya Murashima

“…Portal vein thrombosis is a major complication associated with liver cirrhosis. In cirrhotic patients, a decrease in procoagulant and anticoagulant factors and an unstable balance between them is observed, and a relative decrease in the activation of anticoagulant drivers is one of the main causes of portal vein thrombosis (PVT). …”
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A surrogate BSL2-compliant infection model recapitulating key aspects of human Marburg virus disease by Wanying Yang, Wujie Zhou, Bo Liang, Xiaojun Hu, Shen Wang, Zhenshan Wang, Tiecheng Wang, Xianzhu Xia, Na Feng, Yongkun Zhao, Feihu Yan

“…Syrian hamsters infected with VSV-MARV/GP presented symptoms such as thrombocytopenia, lymphopenia, haemophilia, and multiorgan failure, developing a severe systemic disease akin to that observed in human MARV patients. Notably, the pathogenicity was found to be species-specific, age-related, sex-associated, and challenge route-dependent. …”
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Cell-Based Therapy for Cerebral Palsy: A Puzzle in Progress by Masoumeh Nouri, Morteza Zarrabi, Safdar Masoumi, Elaheh Khodadoust, Anahita Majmae, Man Amanat, Mahmoud Reza Ashrafi, Massoud Vosough

“…However, there is noconsensus on a standard therapeutic protocol regarding the source of cells, optimal cell dose, timing and frequencyof cell injections, route of administration, or the use of combination therapy. …”
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Repeated intravenous infusions of esketamine in inpatients with bipolar depression: A retrospective real-world study by Naima Guhad Shire, Michael Ioannou, Örjan Falk, Ane Bakken Wold, Caroline Wass, Zoltán Szabó, Steinn Steingrimsson

“…However, the optimal administration route and enantiomer (esketamine, arketamine, or racemic mixture) remain unclear. …”
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Effectiveness of Antiviral Treatment with Intravenous Peramivir and Oral Oseltamivir for Seasonal Influenza in Children by Young-hoon Byun, Ji-Eun Kim, So-Hyun Paek, Min-Jung Kim, Soo Hyun Park, Ho-Young Song, Jaehyun Kwon

“…Results: A total of 1327 pediatric patients were included, with 1243 receiving oseltamivir and 84 receiving peramivir. …”
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Intravenous versus subcutaneous tocilizumab in Takayasu arteritis: multicentre retrospective study by Patrice Cacoub, Arsène Mekinian, David Saadoun, Pavel I Novikov, Savino Sciascia, Corrado Campochiaro, Olivier Fain, Ilya Smitienko, Nicolas Schleinitz, Patrick Jégo, Francesco Muratore, Carlo Salvarani, Elena Galli, Sabine Berthier, Marc Lambert, François Maurier, Isabelle Kone-Paut, Sergey Moiseev, Masataka Kuwana, Alexandre Belot, Martin Michaud, Francis Gaches, Achille Aouba, Xavier Puechal, Karim Sacre, Tiphaine Goulenok, Alessandro Tomelleri, Thomas Sené, Elena Marina Baldissera, Luigi Boiardi, Abid Awisat, Ygal Benhamou, Vahan Mukuchyan, Mathieu Vautier, Azeddine Dellal, Lucie Biard, Julie Seguier, José Hernández-Rodríguez, Olivier Espitia, Sebastien Humbert, Guillaume Denis, Nolan Hassold, Dagna Lorenzo, Helene Munoz Pons, Jean Baptiste Gaultier, Le Mouel Edwige, Antoinette Perlat, Bertrand Lioger, Jonathan Broner, Virginie Dufrost, Faten Frikha, Alexandra Audemard-Verger, Pascal Woaye-Hune, Pierre Zeminsky, Moya Alvarado, Matheus Vieira, Alberto Lo Gullo

“…Adverse events occurred in 14 (15%) patients on intravenous route and in 2 (11%) on SC tocilizumab.Conclusion In this study, we confirm that tocilizumab is effective in TAK, with complete remission being achieving by 70% of disease-modifying antirheumatic drugs-refractory TAK patients at 6 months.…”
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Survey of Traveler’s Diarrhea: Epidemiology and Testing Reveal the Source by Zhenguo Gao, Muti Mahe, Shabiremu Tuohetamu, Fang Li, Jian Zhang, Yidan Xia, Xiaona Sun, Abuzhalihan Naerkezi, Ruifang Huang, Hongbin Liu, Daxin Ni, Rong Zhang

“…To understand the causes and transmission routes of, as well as risk factors, for a Salmonella outbreak in a tour group. …”
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Emerging advances in drug delivery systems (DDSs) for optimizing cancer complications by Kerui Li, Bei Guo, Junmou Gu, Na Ta, Jia Gu, Hao Yu, Mengchi Sun, Tao Han

“…In conclusion, DDSs offer promising avenues for treating cancer complications, offering the potential for the development of more effective and safer drug delivery strategies, thereby improving the quality of life and survival rates of cancer patients.…”
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Abuse potential of fentanyl and fentanyl analogues by Anusha Thumma, Kwadwo Mfoafo, Niloofar Babanejad, Alborz Omidian, Yadollah Omidi, Hamid Omidian

“…Introduction: In this perspective review, we evaluated the clinical management of fatal fentanyl overdose in several routes of administration, concentrating on both legally prescribed and illegally produced formulations. …”
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Assessment of Hand-Washing Knowledge and Practice among Nursing Undergraduates in Saudi Arabia by Wajid Syed, Mahmood Basil A. Al-Rawi

“…The present results could support students and health care professionals in improving their hygienic practice, which may help to provide the optimum therapeutic benefits to patients.…”
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Occult Perforation of the Esophagus during Removal of an Enteral Feeding Tube: A Case Report and Literature Review by Mohammad Alabdallat, Gustav Strandvik, Ibrahim Afifi, Ruben Peralta, Ashok Parchani, Ayman El-Menyar, Sandro Rizoli, Hassan Al-Thani

“…The use of oral or nasal route for enteral feeding is a standard practice in intensive care patients with a safe profile in general. …”
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Characterization of acute intoxications in Sancti Spíritus pediatric age, 2014-2018 by Yarelyn Prieto Amude, Karen Remedios Rodríguez, Yanicel Sorí León, Yaumara María León Águila, Raylen Escobar Román

“…The information was obtained through the review of all the medical records of the admitted patients. The variables age, sex, type of circumstantial poisoning, whether intentional or not, place of occurrence; routes of exposure, hospital stay and responsible agent were analyzed. …”
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Fecal Microbiota Transplantation as Therapy for Treatment of Active Ulcerative Colitis: A Systematic Review and Meta-Analysis by Xiaolei Liu, Yan Li, Kaichun Wu, Yongquan Shi, Min Chen

“…FMT delivered via lower gastrointestinal route was superior to upper gastrointestinal route with regard to combined clinical remission with endoscopic remission/response (RR=0.79, 95% CI 0.70-0.89). …”
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Nanocarriers-Assisted Nose-to-Brain Delivery of Levodopa: Current Progress and Prospects by Mariya Dangova, Nadezhda Ivanova, Velichka Andonova

“…While the potential century’s break-through is sought and foreseen by many scientists in gene therapy, immunotherapy, new drug combinations, and neurosurgical approaches, the not-yet-conventional intranasal administration of “classic” levodopa (L-DOPA) also stands out as a perspective from which Parkinson’s patients may benefit in the short term. With the main drawbacks of the standard oral L-DOPA treatment being the extremely low systemic and cerebral bioavailability, it is widely recognized that the nasal route may turn out to be the better administration site, for it offers the alternative of direct brain delivery via the olfactory bulb (the so-called nose-to-brain axis). …”
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Inhaled Drug Delivery: A Practical Guide to Prescribing Inhaler Devices by Pierre Ernst

“…Asthma education will be needed to instruct patients on the effective use of the numerous inhalation devices available.…”
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Two Atypical Cases of Hantavirus Infections from Sri Lanka by N. D. B. Ehelepola, B. M. L. S. Basnayake, S. M. B. Y. Sathkumara, K. L. R. Kaluphana

“…Having arrived at the correct diagnosis late/retrospectively, both these patients recovered notwithstanding being seriously ill, indicating adequate supportive therapy can save lives in such cases. …”
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The role of dendritic cells in tertiary lymphoid structures: implications in cancer and autoimmune diseases by Mariana Reste, Kristi Ajazi, Ayca Sayi-Yazgan, Ayca Sayi-Yazgan, Radmila Jankovic, Biljana Bufan, Sven Brandau, Espen S. Bækkevold, Florent Petitprez, Malin Lindstedt, Gosse J. Adema, Catarina R. Almeida

“…Therefore, it is important to analyze the complex functions of DCs within TLS in order to enhance our fundamental understanding of immune regulation but also as a possible route to create innovative clinical interventions designed for the specific needs of patients with diverse pathological diseases.…”
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