A cost-effectiveness analysis of sotorasib as second-line treatment for patients with KRAS-G12C-mutated metastatic non-small cell lung cancer (mNSCLC) in Switzerland by Tämer El Saadany, Judith Lupatsch, Michael Mark, Michaela Barbier, Tarun Mehra, Matthias Schwenkglenks, Roger von Moos

“…RESULTS: Log-normal functions best fitted the survival curves from CodeBreak 200. …”
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Revised Control Barrier Function with Sensing of Threats from Relative Velocity Between Humans and Mobile Robots by Zihan Zeng, Silu Chen, Xiangjie Kong, Xiaojuan Li, Chi Zhang, Guilin Yang

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Deep functional measurements of Fragile X syndrome human neurons reveal multiparametric electrophysiological disease phenotype by James J. Fink, Nathaniel Delaney-Busch, Ryan Dawes, Evanthia Nanou, Christopher Folts, Karthiayani Harikrishnan, Chris Hempel, Hansini Upadhyay, Trinh Nguyen, Himali Shroff, David Stoppel, Steven J. Ryan, Jane Jacques, Jennifer Grooms, Elizabeth Berry-Kravis, Mark F. Bear, Luis A. Williams, David Gerber, Mark Bunnage, Brinley Furey, Graham T. Dempsey

“…Here, we use a high resolution all-optical electrophysiology platform applied to multiple FXS patient-derived and CRISPR/Cas9-generated isogenic neuronal cell lines to develop a multi-parametric FXS disease phenotype. …”
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Stability Optimization of Explicit Runge–Kutta Methods with Higher-Order Derivatives by Gerasim V. Krivovichev

“…The paper is devoted to the parametric stability optimization of explicit Runge–Kutta methods with higher-order derivatives. …”
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MECHANICAL CALCULATION OF FLEXIBLE WIRES WHEN THE CONCENTRATED FORCES ARE REPLACED BY A DISTRIBUTED LOAD by Yu. V. Bladyko

“…A more accurate calculation of mechanical tensions and sag is possible with the use of a vector-parametric method for calculating the flexible busbar of substations and air-line wires, where the design model of wires in the form of a flexible elastic thread is placed, taking into account the spatial disposition of all structural elements.…”
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Cabozantinib versus everolimus, nivolumab, axitinib, sorafenib and best supportive care: A network meta-analysis of progression-free survival and overall survival in second line tr... by Billy Amzal, Shuai Fu, Jie Meng, Johanna Lister, Helene Karcher

“…The assessment of the proportional hazard (PH) assumption between the survival curves for different treatment arms in the identified studies showed that survival curves in two of the studies did not fulfil the PH assumption, making comparisons of constant hazard ratios (HRs) inappropriate. Consequently, a parametric survival network meta-analysis model was implemented with five families of functions being jointly fitted in a Bayesian framework to PFS, then OS, data on all treatments. …”
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Invariance Property of Cauchy–Stieltjes Kernel Families Under Free and Boolean Multiplicative Convolutions by Fahad Alsharari, Raouf Fakhfakh, Fatimah Alshahrani

“…This article delves into some properties of free and Boolean multiplicative convolutions, in connection with the theory of Cauchy–Stieltjes kernel (CSK) families and their respective variance functions (VFs). Consider <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi mathvariant="script">K</mi><mo>−</mo></msub><mrow><mo>(</mo><mi>μ</mi><mo>)</mo></mrow><mo>=</mo><mrow><mo>{</mo><msubsup><mi>Q</mi><mi>m</mi><mi>μ</mi></msubsup><mrow><mo>(</mo><mi>d</mi><mi>s</mi><mo>)</mo></mrow><mo>:</mo><mspace width="4pt"></mspace><mspace width="4pt"></mspace><mi>m</mi><mo>∈</mo><mrow><mo>(</mo><msubsup><mi>m</mi><mo>−</mo><mi>μ</mi></msubsup><mo>,</mo><msubsup><mi>m</mi><mn>0</mn><mi>μ</mi></msubsup><mo>)</mo></mrow><mo>}</mo></mrow></mrow></semantics></math></inline-formula>, a CSK family induced by a non-degenerate probability measure <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>μ</mi></semantics></math></inline-formula> on the positive real line with a finite first-moment <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msubsup><mi>m</mi><mn>0</mn><mi>μ</mi></msubsup></semantics></math></inline-formula>. …”
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Singular Points of Curves by Artem D. Uvarov

“…In the first part of the paper, the problem of determining the tangent line of two surfaces given in parametric form is considered. …”
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On Statistical Properties of a New Bivariate Modified Lindley Distribution with an Application to Financial Data by Ahmed Elhassanein

“…The one-parameter modified Lindley distribution is used as a base line to construct the new model. Its statistical properties including cumulative function, density function, marginals, moments, conditional distributions, and copula are discussed. …”
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基于实际设计齿廓斜齿轮的三维建模与有限元分析 by 王丽娜, 王铁, 张瑞亮

“…Taking into account the actual processing conditions in line with the actual design,through the creation of the filet curve,a deflection gear three-dimensional model is established by Pro/E parametric modeling function,and two gears model are analyzed and compared by Marc software.…”
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Drug induced liver injury in HIV patients on dolutegravir based antiretroviral therapy regimens in Wolaita Sodo comprehensive specialized hospital by Firew Abraham, Alemayehu Toma, Tamrat Balcha, Bereket Molla Tigabu

“…Dolutegravir (DTG) based combination antiretroviral therapy (ART) is currently first line treatment for HIV infected patients in Ethiopia. …”
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THE URBAN METRO TRANSIT’S PERFORMANCE EVALUATION USING SUPER-DEA by Salman KHURSHEED, Shagufta YASMIN, Farhan Ahmad KIDWAI

“…., Delhi Metro is investigated using Data Envelopment Analysis (DEA) and Super-DEA approaches. DEA is a non-parametric technique used in the estimation of production functions and has been used extensively to estimate measures of technical efficiency. …”
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Finding the optimal way to build an information security system based on Markov chains by A. M. Konakov, I. I. Livshits

“…In this subject area, the possibilities of structural-parametric models and Markov chains for identifying the optimal line for constructing a multi-level information security system are considered. …”
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Influence of Gait Speed on Inter-Joint Coordination in People with and Without Parkinson’s Disease by Patrick Ippersiel, Philippe C. Dixon, Elke Warmerdam, Robbin Romijnders, Walter Maetzler, Clint Hansen

“…Participants walked in a straight line at slow, preferred, and fast walking speeds. …”
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The impact of herd age structure on the performance of commercial sow-breeding farms by Santos Sanz-Fernández, Cipriano Díaz-Gaona, João Simões, José Carlos Casas-Rosal, Nuria Alòs, Llibertat Tusell, Raquel Quintanilla, Vicente Rodríguez-Estévez

“…Results Farms are classified into three groups according to the quadratic function fitted to the percentage of sows by parities. …”
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Neural Networks as Positive Linear Operators by George A. Anastassiou

“…I explore the space of continuous functions on a compact interval of the real line to the reals. …”
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Optimized design of B-B surface through Bézier geodesic trilateral(过Bézier测地三边形的B-B曲面优化设计) by 马乐婷(MA Leting), 杨火根(YANG Huogen), 孙源(SUN Yuan)

“…Firstly, the boundary geodesic interpolation condition is used to determine the two rows of control points of the surface boundary line and adjacent boundary line; Secondly, two methods of minimizing surface Bending energy functional and Dirichlet energy functional are given to optimize the remaining control points of the surface. …”
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Approximation of the Profile of Gas Turbine Engine Blades by M. E. Soloviev, Y. N. Shuleva, S. L. Baldaev, L. Kh. Baldaev

“…It provided the calculation of the coefficients of approximating polynomials for the contour lines of the blade, visualization of the calculation results, and creation of a dxf file based on the points of approximating functions to transfer it to the CAD system. …”
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APPROACH OF PROCESSING, CLASSIFICATION AND DETECTION OF NEW CLASSES AND ANOMALIES IN HETEROGENIOUS AND DIFFERENT STREAMS OF DATA by R. A. Bagutdinov

“…New class detection strategies are classified as parametric and non-parametric. This work is based on a non-parametric approach. …”
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Transcriptome and Proteome Analysis Identified Genes/Proteins Involved in the Regulation of Leaf Color in <i>Paulownia fortunei</i> by Hu Li, Weili Tian, Yongming Fan

“…Chlorophyll content analysis showed a decrease in the chlorophyll b content in the mutant line. Non-parametric transcriptome and proteome analyses were performed to screen for genes and proteins active in the regulation of <i>P. fortunei</i> greening. qRT-PCR was carried out to confirm 10 genes identified in the transcriptome. …”
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