Clinical pathological features and prognosis of diabetic nephropathy patients with stage 4 chronic kidney disease by YU Tian-yu, JIANG Shi-min, YANG Yue, FANG Jin-ying, GAO Hong-mei, ZOU Gu-ming, LI Wen-ge

“…Objective To investigate the relationship of clinical manifestations and pathological features with prognosis of diabetic nephropathy（DN） patients with stage 4 chronic kidney disease（CKD）.Methods The study subjects were those patients,who were diagnosed as DN by renal biopsy pathology with renal function in stage 4 CKD in Department of Nephrology of Chino-Japan Friendship Hospital from January 2005 to August 2019.The follow-up deadline was either the primary endpoint or until November 30,2019.The primary endpoints of observation were initiation of maintenance kidney replacement therapy,death or estimated glomerular filtration rate（eGFR） less than 15 mL·min^-1·（1.73 m²）^-1.The secondary endpoints were cardiovascular and cerebrovascular events.Based on the pathological classification of renal biopsy,the clinical and pathological parameters of the patients were respectively analyzed and survival analysis was performed.Results A total of 24 patients were included in the study,3 cases of type Ⅱa,with 3 cases of type IIb,15 cases of type III and 3 cases of type IV.The total median follow-up time was 20.7（range 5.9～72.4） months.The total median survival time was 17.3 months.7 patients with stage 4 CKD were still maintained,with the median follow-up time of 14.6（range 5.9～46.8） months;17 patients developed the primary endpoint event,with the median follow-up time of 14.2（range 6.1～72.4） months.The renal cumulative survival rates in 6 months,12 months and 18 months were 82.6%,59.3% and 41.6%,respectively.The comparison between the two groups with and without the primary endpoint events showed that systolic blood pressure and cardiovascular events were statistically different（P<0.05）.Conclusions The median survival time of progression to composite kidney endpoint events in DN patients with stage 4 CKD is 17.3 months.Control level of blood pressure and cardiovascular events might be the major relevant factors in progression of renal function.…”
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Retrospective evaluation of novel serum inflammatory biomarkers in first-episode psychiatric disorders: diagnostic potential and immune dysregulation by Min Qiu, Chenkai Zhang, Haiqing Zhang, Hao Chen, Yingjia Lei, Ping Li, Shaochuan Zhang

“…The area under the curve (AUC) value of the NHR + MHR + NLR composite index model for the SCZ group was 0.846 (p &lt; 0.001). …”
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Prediction of Unconfined Compressive Strength of Expansive Soil Amended with Bagasse Ash and Lime Using Artificial Neural Network by D.R. Goutham, A.J. Krishnaiah

“…Due to the complexities of this composite material, determining the UCS of stabilized ES using traditional methods such as empirical approaches and experimental methods is challenging. …”
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Ion homeostasis in the regulation of intracellular pH and volume of human erythrocytes by О. І. Доценко, Г. В. Тарадіна

“…Results: The kinetic model of erythrocyte ion homeostasis was created. Using realistic parameters of the system changes over time in cell volume, concentrations of metabolites, ions fluxes and transmembrane potential were calculated. …”
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Degradation of Low-Molecular-Weight Diesel Fractions (C₁₀−C₁₆ Alkane) Drives Cd Stabilization and Pb Activation in Calcareous Soils from Karst Areas by Yiting Huang, Yankui Tang, Zhenze Xie, Jipeng Wu, Jiajie Huang, Shaojiang Nie

“…This study systematically investigated how compositional changes in diesel fuel during aging regulated the fate of Cd and Pb in calcareous soils. …”
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Evaluation of ZnO/NiO/kaolin nanocomposite as a sorbent/photocatalyst in hybrid water remediation process by Sarah A. Farag, M. Farouk, Nabila Shehata

“…The impacts of various parameters, such as pH, initial concentration of MB, dose, ionic strength, and temperature, on MB removal were studied using adsorption and APCD. …”
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Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients by Younggwang Kim, Min Ki Kim, Sanghun Lee, Sanghun Lee, Sanghun Lee

“…Diagnostic performance was evaluated with ROC curves, and associations with clinical parameters were assessed via regression models.ResultsBeta diversity revealed significant compositional differences between fecal and mucosal samples (p = 0.001), with mucosal samples showing higher enrichment of CRC-associated taxa. …”
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A new digital biomarker of Demodex blepharitis: energy curve of the meibomian edge by Minjia Wang, Xiaoyu Chen, Kesheng Wang, Kunhui Xu, Xinxin Yu, Qi Dai, Qi Dai, Min Ren

“…The lower margin curve of MGs was extracted using an active contour model (Snake) to compute a composite energy value that integrates elastic, curvature, and smoothness energies. …”
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Critical Condition of Core-collapse Supernovae. I. One-dimensional Models by David Pochik, Todd A. Thompson

“…We derive ${L}_{\nu }^{{\rm{crit}}}$ as a function of the input parameters. We show that increasing the pressure of the pre-shock flow, as parameterized by lowering ${ \mathcal M }$ , lowers the normalization of the critical condition. …”
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Pharmaceutical development of sangviritrin spray for the treatment of inflammatory diseases of the oral cavity by M. N. Anurova, Ya. A. Dorokhina, A. S. Gulenkov, N. B. Demina, L. A. Korol, P. G. Mizina

“…Optimal auxiliary component compositions were selected based on measurements of spray technological parameters. …”
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Prediction of Temperature Distribution with Deep Learning Approaches for SM1 Flame Configuration by Gökhan Deveci, Özgün Yücel, Ali Bahadır Olcay

“…The first approach employs a fully connected dense neural network to directly map scalar input parameters—fuel velocity, swirl ratio, and equivalence ratio—to high-resolution temperature contour images. …”
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Surface-engineered chitosan-coated nanostructured lipid carriers for intranasal delivery of Oxcarbazepine and Vitamin E oil in epilepsy management by Farhan Haider, Eman Aldosari, Rabea Parveen, Sanjula Baboota, Azka Gull, Saba Khan, Javed Ali

“…The pharmacokinetic parameters and biodistribution of OXC levels in the brain and plasma were duly examined. …”
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Moringa oleifera Ethanolic Extract Prevents Oxidative Damage on Lens Caused by Sodium Valproate Used in Epilepsy Treatment by Eda Dağsuyu, Umar Faruk Magaji, Özlem Saçan, Refiye Yanardağ

“…In contrast, changes in the levels of these parameters were offset in the VPA+M group by Moringa extract.Conclusion: This suggests that Moringa oleifera leaves are an excellent nutritional composite for mitigating the damaging properties of VPA.…”
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Relationship between physical function and sarcopenia in the older adults from Amazonas: A cross-sectional study. by Alex Barreto de Lima, Duarte Henrinques-Neto, David Scott, André de Araújo Pinto, Gustavo Dos Santos Ribeiro, Miguel Peralta, Kessketlen Alves Miranda, Pedro Campos, Elvio Rúbio Gouveia

“…Most physical function parameters in the crude analysis were associated with confirmed sarcopenia (all p < 0.05), except for the back scratch test. …”
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Aspergillus foetidus as a potent producer for β-galactosidase utilizing lemon peels and coffee waste powder: production optimization, purification, kinetic and thermodynamic charac... by Walaa A. Abdel Wahab, Shireen A. A. Saleh, Nermeen H. Elzairy, Samia A. Ahmed, Eman R. Zaki, Walaa H. Salama, Faten A. Mostafa

“…Followed by Central Composite Design investigating each factor with five levels resulting in 37363.1 U.ml− 1 production. …”
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Numerical Analysis of Load Reduction in the Gliding Process Achieved by the Bionic Swan’s Webbed-Foot Structures by Fukui Gao, Xiyan Liu, Xinlin Li, Zhaolin Fan, Houcun Zhou, Wenhua Wu

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Electrodeposited CdTe solar cells using low-purity Cd precursors &amp; the effect of chemical purity by Ashfaque E. Alam, Hussain I. Salim, Ayotunde A. Ojo, Imyhamy M. Dharmadasa

“…A comprehensive comparison with the previous works carried out with higher-purity chemicals has been performed for both the material properties and device parameters achieved using low-purity Cd precursors. …”
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Estimation of compressive strength of ultra-high performance lightweight concrete (UHPLC) using neural network. by Yan Zhao, Ziyan Huang, Huilong Zhao, Zhen Xu, Wei Chang, Bai Liu

“…Three strategies were proposed for creating ultra-high-performance lightweight composites: optimizing packing density and lowering the water-binder ratio, along with careful selection of lightweight aggregates.…”
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Structural strength optimization design of ultra-high-pressure and ultra-wear-resistant pneumatic ball valve opened and closed at large explosion instantaneously using finite eleme... by Xianmei Liu, Mingcun Zhang

“…At the same time, the elastic modulus degradation effect of tungsten carbide/nickel-based alloy composites caused by frictional heat is considered, and the wear rate is calculated based on the wear model Archard. …”
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Preparation and Performance Evaluation of TiO2 incorporated Fly Ash-Kaolin Ceramic Membrane for Oil/Water Separation by Eny Apriyanti, Heru Susanto, I Nyoman Widiasa

“…The XRD pattern of all formulated membranes showed almost no change, however, the crystal intensity varied due to the different ceramic compositions. P hysicochemical properties evaluation showed that the membrane with fly ash, kaolin, and alumina of 20 : 30 : 40 wt% has reached the best characteristic. …”
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