Supporting self-management of low back pain with an internet intervention in primary care: a protocol for a randomised controlled trial of clinical and cost-effectiveness (SupportB... by Beth Stuart, Paul Little, Lucy Yardley, Stephanie Hughes, Adam W A Geraghty, Elaine Hay, Gemma Mansell, Nadine E Foster, Jonathan Hill, Gareth Griffiths, Frances Webley, Lorraine Durcan, Alannah Morgan, Sarah Bathers, Stephanie Butler-Walley, Simon Wathall, Linda Leigh

“…Introduction Self-management and remaining physically active are first-line recommendations for the care of patients with low back pain (LBP). With a lifetime prevalence of up to 85%, novel approaches to support behavioural self-management are needed. …”
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Efficacy and tolerability of low versus standard daily doses of antiseizure medications in newly diagnosed focal epilepsy. A multicenter, randomized, single‐blind, non‐inferiority... by Giorgia Giussani, Elisa Bianchi, Edoardo Carlando, Jacopo Cosimo DiFrancesco, Payam Tabaee Damavandi, Francesco Pasini, Giulia Pederzoli, Stefania Filipponi, Alessandra Gaiani, Luca Massacesi, Eleonora Rosati, Ginevra Giovannelli, Teresa Anna Cantisani, Michela Cecconi, Rossella Papetti, Monica Brioschi, Francesco Aruta, Elio Clemente Agostoni, Francesco Paladin, Filippo Dainese, Marco Longoni, Bartolini Yerma, Sara Gasparini, Umberto Aguglia, Edoardo Ferlazzo, Roberto Cantello, Gionata Strigaro, Marta Maschio, Dario Benincasa, Angela La Neve, Giovanni Falcicchio, Alfonso Giordano, Lara Buttarelli, Gabriele Enia, Maurizio Leone, Carlo Ferrarese, Ettore Beghi, Simone Beretta

“…Methods Multicenter, randomized, parallel‐arm, single‐blind, non‐inferiority trial, comparing low dose versus standard dose of antiseizure medications (carbamazepine, levetiracetam, valproate, zonisamide, oxcarbazepine, topiramate, lamotrigine, gabapentin, lacosamide) in adults with newly diagnosed focal epilepsy. …”
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Low-added sugar dietary intervention study to mitigate glucose intolerance and improve body composition in adults with cystic fibrosis: a protocol of a double-blind, randomised stu... by Priyathama Vellanki, Kirk Easley, Terryl J Hartman, Thomas R Ziegler, Puneet Sharma, Swati Zaveri, Arlene Stecenko, William R Hunt, Amy Goss, Joshua D Chandler, Tasha M Burley, Chris Driggers, Amy Ciccarella, Heather Zhou, Kristen Narlow, Tanicia Daley, Jessica Alvarez

“…., sugar not naturally occurring in foods) has been shown to be increased in PwCF and this excess intake of added sugar could increase the risk of CFRD.Methods and analysis/design The goal of this ongoing double-blind, randomised, parallel-group clinical trial is to recruit approximately 60 clinically stable adults with CF to determine if a low-added sugar intervention improves beta-cell responsiveness and insulin sensitivity (Aim 1), reduces visceral adipose tissue (VAT) and other ectopic fat deposition (Aim 2) and improves plasma redox status (Aim 3) over 8 weeks compared with a typical CF diet. …”
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Laser-Assisted Orthodontic Tooth Movement in Saudi Population: A Prospective Clinical Intervention of Low-Level Laser Therapy in the 1st Week of Pain Perception in Four Treatment M... by Mohammad Khursheed Alam

“…This first-in-human study in Saudi orthodontic patients has evaluated the role of low-level laser therapy (LLLT) in pain perception (PP). …”
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Protocol for a randomised controlled trial of the combined effects of the GLP-1 receptor agonist liraglutide and exercise on maintenance of weight loss and health after a very low-... by Mads Rosenkilde, Bente Merete Stallknecht, Simon Birk Kjær Jensen, Julie Rehné Lundgren, Charlotte Janus, Christian Rimer Juhl, Lisa Møller Olsen, Sten Madsbad, Signe Sørensen Torekov

“…Therefore, the purpose of this study is to investigate the maintenance of weight loss and immunometabolic health outcomes after diet-induced weight loss followed by 1-year treatment with a glucagon-like peptide-1 receptor agonist (liraglutide), physical exercise or the combination of both treatments as compared with placebo in individuals with obesity.Methods and analysis This is an investigator-initiated, randomised, placebo-controlled, parallel group trial. We will enrol expectedly 200 women and men (age 18–65 years) with obesity (body mass index 32–43 kg/m2) to adhere to a very low-calorie diet (800 kcal/day) for 8 weeks in order to lose at least 5% of body weight. …”
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Educational interventions delivered to prescribing advisers to influence primary care prescribing: a very low-cost pragmatic randomised trial using routine data from OpenPrescribin... by Helen J Curtis, Brian MacKenna, Bhavana Reddy, Alex J Walker, Sebastian Bacon, Rafael Perera, Ben Goldacre

“…We aimed to monitor the impact of an educational intervention delivered to regional prescribing advisors by senior pharmacists from NHS England on the primary care spend on low-priority items. Methods An opportunistic randomised, controlled parallel-group trial. …”
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Enhancing Neural Machine Translation Quality for Kannada–Tulu Language Pairs through Transformer Architecture: A Linguistic Feature Integration by Musica Supriya, U Dinesh Acharya, Ashalatha Nayak

“…The proposed generic approach can benefit other low-resource Indic languages that have smaller parallel corpora for NMT tasks. …”
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Evaluation of the skeletal, dental, and soft-tissue changes after the en-masse retraction of upper anterior teeth stimulated by low-intensity electrical current: a randomized contr... by Rashad I. Shaadouh, Mohammad Y. Hajeer, Mohammad Khursheed Alam, Kinda Sultan, Ossama Aljabban

“…Abstract Background Low-intensity electrical stimulation (LIES) is one of the recent physical techniques employed to accelerate orthodontic tooth movement and reduce treatment time. …”
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Investigation on the Acoustic Performance of Micro-Perforated Panel Integrated Coiled-Up Space Acoustic Absorber by Damodaran Sanalkumar Govind Krishna, Parvathy Arun Leena, Abhinav Karottuthundathil, Ashidha Mohammed, Mahesh Kavungal, Mini Rema Sahadevan

“…In this study, a parallel arrangement of a coiled-up space cavity and micro-perforated panel (MPP) is considered as the absorber configuration. …”
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Characterization of the Differences in Dissolved Organic Matter (DOM) Adsorbed on Five Kinds of Microplastics Using Multiple Methods by Xianshu Fu, Xiangliang Pan, Jun Chen, Mingzhou Zhang, Zihong Ye, Xiaoping Yu

“…Excitation-emission matrix-parallel factor analysis (EEM-PARAFAC) identified that tyrosine-like substances with high excitation in region IV and low excitation in region I were predominantly adsorbed on MPs, followed by tryptophan-like substances with low excitation in region II and protein-like substances in region IV, while humic- and fulvic-like substances in regions V and III, respectively, exhibited the least adsorption affinity. …”
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The BumbleBox: An open‐source platform for quantifying behaviour in bumblebee colonies by August Easton‐Calabria, James D. Crall

“…Practical implication: The BumbleBox system is designed to be (a) accessible, requiring no prior experience with programming or hardware design to operate; (b) scalable, allowing long‐term, automated tracking across many units in parallel at low cost; and (c) modular, allowing for flexible adoption to unique applications in bumblebees and other systems. …”
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The effect of hypocapnia on systemic perfusion in patients with single ventricle after surgery by A. В. Naumov, G. G. Khubulava, Yu. S. Аleksandrovich, S. P. Marchenko, К. V. Pshenisnov, N. G. Pilyugov

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Spasm and electromyography intensity of bilateral extensor during relaxation period in trunk anterior flexion–extension performance response to sustained asymmetry spinal loading by Longzhen Wang, Jingyuan Wang, Wenjin Wang, Xiangrong Cheng, Wenrong Wang, Xinhai Shan

“…It may indicate that sustained asymmetry spinal loading could lead to a weakness for tension ability, and/or a micro-damage in spinal bilateral passive tissues in low back area, the risk of developing low back disorder.…”
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Social Health Insurance for Universal Health Coverage in Low and Middle-Income Countries (LMICs): a retrospective policy analysis of attainments, setbacks and equity implications o... by Jonathan Filippon, Giuliano Russo, Susan Nungo

“…Only 27% of the informal economy is covered by the NHIF, implying very low uptake and/or retention rates. We found little stakeholder engagement in the policy implementation process and minimum adoption of expert advice. …”
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Clinical Surveillance vs. Anticoagulation For low-risk patiEnts with isolated SubSegmental Pulmonary Embolism: protocol for a multicentre randomised placebo-controlled non-inferior... by Marc Carrier, Christine Baumgartner, Drahomir Aujesky, Menno V Huisman, Frederikus A Klok, Jeanne Moor, Marc Righini, Jürg-Hans Beer, Martina Peluso, Damiana Rakovic

“…Anticoagulation For low-risk patiEnts with isolated SubSegmental Pulmonary Embolism, a multicentre randomised placebo-controlled non-inferiority trial) is an international, multicentre, placebo-controlled, double-blind, parallel-group non-inferiority trial conducted in Switzerland, the Netherlands and Canada. …”
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Dynamic impact mechanical damage analysis and tomato robotic post-picking crating optimization based on multiscale finite element model by Guohang Lu, Zinuo Wang, Nianzu Dai, Jin Yuan, Xuemei Liu, Georgios Papadakis

“…Efficiency of harvesting robots remains a major bottleneck for increasing productivity, and the usual approach is to improve the parallelism between fruit separation and fruit crating. …”
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Towards Fast Implementation of Complex RNS Components on FPGAs by Sabbagh Molahosseini Amir, Alsadat Emrani Azadeh

“…The efficient hardware implementation of RNS particularly on field program-mable gate array (FPGA) is very important due to the use of FPGAs in some modern computing systems to achieve flexibility and low time-to-market. The residue number system (RNS) with its inherent parallelism can also be used to enhance the performance of implementation of comput-ing algorithms on FPGAs. …”
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Experimental study on characteristics of Jiamin damage in high-volatile bituminous coal reservoirs by Xin LI, Shitao DU, Shuguang YANG, Bo WEI, Ziqiang WANG, Yanpeng CHEN, Zhenpeng HU, Ming CHENG, Xuehai FU, Junqiang KANG

“…The results show that: ① The permeability of the water phase in the parallel bedding coal sample (0.872×10−3～1.066×10−3 μm2) in the single-phase flow stage is one order of magnitude higher than that of the vertical bedding coal sample (0.064×10−3～0.112×10−3 μm2). …”
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Launching to an orbit with a chemical propellant staged rocket systems by Erk İnger

“…At low level starting to high altitude higher density fuel solid fuels, kerogen and cryogenic hydrogen(-250°C) are used as fuel. …”
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Characterizing a standard cell library for large scale design of memristive based signal processing by Abubaker Sasi, Arash Ahmadi, Majid Ahmadi

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