Levetiracetam versus Phenobarbitone in Neonatal Seizures - An Open label Randomized Controlled Trial by Nikhil D Kulkarni, Suman Rao P N, B Lakshmi Parvathi, Swarnarekha Bhat

“…An open-label parallel randomized controlled trial RCT was conducted in a neonatal intensive care unit NICU in IndiaResultsnbspSeizure cessation rates were 70 in the levetiracetam group and 66.6 in the phenobarbitone group with no statistically significant difference P 0.83.ConclusionnbspLevetiracetam and phenobarbitone demonstrated comparable efficacy and safety in managing neonatal seizures. …”
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A case study of enzootic bovine leucosis in an Albanian dairy herd based on serological and hematological tests results by Majlind Sulce, Anita Koni, Gerald Muca, Pllumb Zalla, Albana Munga, Valentin Shtjefni, Xhelil Koleci

“…Results suggest that strategic use of hematological and AGID tests in parallel can increase the sensitivity of diagnosis and facilitate the detec-tion of infected animals in different disease stages. …”
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Pressure and angle of the seed-fertilizer drill press wheel on corn emergence by Dailson Dugato, Marcos A. Z. Palma

“…However, the treatment with highest load and parallel alignment of the wheels caused lower values of elevated area and swelling. …”
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Golimumab in the treatment of extra-skeletal manifestations of ankylosing spondylitis by A. B. Demina

“…Extra-skeletal manifestations (EMs) of ankylosing spondylitis (AS) can occur and proceed in parallel with inflammatory changes in the joints and spine and often dominate in the clinical picture of AS, determining its high activity and significantly worsening the quality of life in patients. …”
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Task-sharing with lay counsellors to deliver a stepped care intervention to improve depression, antiretroviral therapy adherence and viral suppression in people living with HIV: a... by Kimberley Goldsmith, Barbara M Barrett, Dixon Chibanda, Melanie Abas, Conall O’Cleirigh, Walter Mangezi, Primrose Nyamayaro, Rebecca Jopling, Tarisai Bere, Samantha M McKetchnie, Calvin Fitch, Emily Saruchera, Thabani Muronzie, Denford Gudyanga, James Hakim, Steven A Safren

“…This paper describes the protocol for a 2-arm parallel group superiority 1:1 randomised controlled trial, to test the effectiveness and cost effectiveness of the TENDAI stepped care task-shifted intervention for depression, ART non-adherence and HIV viral suppression delivered by lay interventionists.Methods and analysis Two hundred and ninety people living with HIV aged ≥18 years with probable depression (Patient Health Questionnaire=>10) and viral non-suppression (≥ 1000 HIV copies/mL) are being recruited from HIV clinics in towns in Zimbabwe. …”
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Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness. by Els Torreele, Bernadette Bourdin Trunz, David Tweats, Marcel Kaiser, Reto Brun, Guy Mazué, Michael A Bray, Bernard Pécoul

“…<h4>Methods and findings</h4>Standard in vitro and in vivo anti-parasitic activity assays were conducted to assess drug efficacy in experimental models for HAT. In parallel, a full range of preclinical pharmacology and safety studies, as required by international regulatory guidelines before initiating human studies, have been conducted. …”
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Yoga programme for type-2 diabetes prevention (YOGA-DP) among high risk people in India: a multicentre feasibility randomised controlled trial protocol by Mark Hamer, Dorairaj Prabhakaran, Kavita Singh, Nikhil Tandon, Sanjay Kinra, Kaushik Chattopadhyay, Tess Harris, Pallavi Mishra, Sheila Margaret Greenfield, Sarah Anne Lewis, Nandi Krishnamurthy Manjunath, Rukamani Nair, Somnath Mukherjee, David Ross Harper

“…The exercise part is based on Yoga and includes Shithilikarana Vyayama (loosening exercises), Surya Namaskar (sun salutation exercises), Asana (Yogic poses), Pranayama (breathing practices) and Dhyana (meditation) and relaxation practices.Methods and analysis This is a multicentre, two-arm, parallel-group, feasibility RCT with blinded outcome assessment and integrated mixed-methods process evaluation. …”
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A Representation-Learning-Based Graph and Generative Network for Hyperspectral Small Target Detection by Yunsong Li, Jiaping Zhong, Weiying Xie, Paolo Gamba

“…The mini-batch-training pattern of the GCN decreases the high computational cost of building an adjacency matrix for high-dimensional data sets. In parallel, the generative model enhances the differentiation reconstruction and the deep feature representation ability with respect to the target spectral signature. …”
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Efficacy and Safety of a Novel Tapered-Tip Sheath System for Biliary-Lesion Tissue Sampling: A Randomized Controlled Trial by Hirokazu Okada, Norimitsu Uza, Tomoaki Matsumori, Hajime Yamazaki, Muneji Yasuda, Takeshi Kuwada, Yoshihiro Nishikawa, Takahisa Maruno, Masahiro Shiokawa, Atsushi Takai, Ken Takahashi, Akihisa Fukuda, Etsuro Hatano, Sachiko Minamiguchi, Hiroshi Seno

“…Background/Aims: Pathological evaluation is crucial for diagnosing biliary lesions and determining appropriate treatment strategies. …”
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Autism Transition to Adulthood Groups (ATAG): protocol for a feasibility RCT of a new peer-group intervention to promote successful transition to adulthood for autistic young peopl... by Bryony Beresford, Annabel Burnley, W Mandy, Ailsa Russell, Kate Cooper, Leon Allain, Laura Crane, Maximiliano Vazquez Morales, Lucy Portway, Benjamin Redmayne

“…Objectives included assessing recruitment and retention rates, acceptability of procedures, characterising usual care, assessing the acceptability of UYDY and care as usual (CAU) and calculating outcome measure variances for a full trial.Methods and analysis This two-arm parallel feasibility RCT includes a nested qualitative evaluation. …”
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TRAF2 and RIPK1 redundantly mediate classical NFκB signaling by TNFR1 and CD95-type death receptors by Jennifer Wagner, David Vredevoogd, Xin Yu, Dong Lu, Daniel S. Peeper, Heike M. Hermanns, Jin Wang, Harald Wajant, Daniela Siegmund

“…Moreover, with exception of recruitment of TRADD, acting upstream to TRAF2 and parallel to RIPK1, TNFR1 signaling complex formation was abrogated in TRAF2-RIPK1 DKO cells. …”
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Benefits, burden, and harms of computer aided polyp detection with artificial intelligence in colorectal cancer screening: microsimulation modelling study by Cesare Hassan, Alessandro Repici, Farid Foroutan, Lise M Helsingen, Michael Bretthauer, Mette Kalager, Marco Spadaccini, Yuichi Mori, Magnus Løberg, Per Olav Vandvik, Loredana Correale, Natalie Halvorsen, Nastazja Pilonis, Shanaz Sultan

“…The certainty in each outcome was assessed by use of the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach.Results For 100 000 individuals participating in colonoscopy screening, 824 (0.82%) were diagnosed with colorectal cancer within 10 years without CADe versus 713 (0.71%) with CADe (risk difference –0.11% (95% CI –0.43% to 0.21%)). …”
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Supporting self-management of low back pain with an internet intervention in primary care: a protocol for a randomised controlled trial of clinical and cost-effectiveness (SupportB... by Beth Stuart, Paul Little, Lucy Yardley, Stephanie Hughes, Adam W A Geraghty, Elaine Hay, Gemma Mansell, Nadine E Foster, Jonathan Hill, Gareth Griffiths, Frances Webley, Lorraine Durcan, Alannah Morgan, Sarah Bathers, Stephanie Butler-Walley, Simon Wathall, Linda Leigh

“…A full mixed-methods process evaluation will be conducted.Ethics and dissemination This trial has been approved by a National Health Service Research Ethics Committee (REC Ref: 18/SC/0388). …”
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Effectiveness and Safety of a Dermocosmetic Cream as an Adjunct to Adapalene for Mild and Moderate Acne in Indonesia: Results of a Multicenter Randomized Controlled Study by Sitohang IBS, Norawati L, Yenny SW, Kusumawardani A, Murlistyarini S, Setiawan SV, Kekalih A, Riany G, Kerob D

“…This study was conducted to determine the effectiveness and safety of a dermocosmetic cream containing salicylic acid, lipohydroxy acid, niacinamide, Aqua posae filiformis, procerad and zinc salt in the treatment of mild-to-moderate acne vulgaris in adjunct to different regimens of adapalene compared to adapalene only.Patients and Methods: This randomized, controlled, parallel-group, evaluator-blind study was conducted over 8 weeks on male and female acne subjects at five teaching hospitals in Indonesia. …”
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Rehabilitation using virtual gaming for Hospital and hOMe-Based training for the Upper limb in acute and subacute Stroke (RHOMBUS II): results of a feasibility randomised controlle... by Cherry Kilbride, Tom Butcher, Meriel Norris, Nana Anokye, Alyson Warland, Karen Baker, Dimitrios A Athanasiou, Guillem Singla-Buxarrais, Jennifer Ryan, Francesca Gowing, Elmar Kal, Carole Pound, Victoria Stewart, Basaam Aweid, Arul Samiyappan

“…Objective To investigate the safety, feasibility and acceptability of the Neurofenix platform for upper-limb rehabilitation in acute and subacute stroke.Design A feasibility randomised controlled trial with a parallel process evaluation.Setting Acute Stroke Unit and participants’ homes (London, UK).Participants 24 adults (&gt;18 years), acute and subacute poststroke, new unilateral weakness, scoring 9–25 on the Motricity Index (elbow and shoulder), with sufficient cognitive and communicative abilities to participate.Interventions Participants randomised to the intervention or control group on a 2:1 ratio. …”
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Assessment of Reactogenicity and Immunogenicity of the Quadrivalent Live Attenuated Influenza Vaccine by D. A. Lioznov, S. M. Kharit, M. K. Erofeeva, T. G. Zubkova, O. V. Gorchakova, S. L. Nikolaenko

“…In this multicenter double blind randomized clinical study with parallel groups conducted with 612 healthy volunteers, domestic influenza quadrivalent inactivated subunit vaccine Grippol® Quadrivalent safety, tolerability and immunogenicity was evaluated in comparison with seasonal trivalent vaccines, It was demonstrated that quadrivalent influenza vaccine Grippol® Quadrivalent possesses good tolerability, low reactogenicity, and has favorable safety profile similar to that for trivalent comparators. …”
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Impact of fractures on convective-mixing characteristics of carbon dioxide in saline aquifers by Qigui TAN, Jian TIAN, Ruichao TIAN, Haoping PENG

“…In aquifers with combined fractures, horizontal parallel fractures create backflow patterns similar to low-angle fractures. …”
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Investigation of Three-Dimensional Deformation Behavior due to Long and Large Excavation in Soft Clays by Chunhui lou, Tangdai Xia, Nianwu Liu, Xiaonan Gong

“…Thus, a modified function for estimating the distribution of deformation parallel to the excavation is proposed and evaluated. …”
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An Innovative Adaptive-Dimension Accordion Honeycomb for Circumferential Deformation by Hairui Zhang, Xianhang Li, Jiayuan Yang, Jingsong Yang

“…We derive the circumferential stiffness of both the unit cell and the honeycomb through analytical and theoretical approaches based on the series–parallel mechanism (SPM), validated using finite element modeling (FEM). …”
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Speaker Recognition Using Wavelet Packet Entropy, I-Vector, and Cosine Distance Scoring by Lei Lei, She Kun

“…To reduce the time cost, the parallel computation is used.…”
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