Assessment of knowledge, attitudes, and performance of postgraduate nursing students regarding clinical reasoning and evidence-based nursing: a multicenter cross-sectional study in... by Zahra Mohebi, Azizallah Dehghan, Ali Taghinezhad, Sorur Javanmardifard, Mostafa Bijani

“…This study, therefore, aims to evaluate postgraduate nursing students’ knowledge, attitudes, and performance regarding clinical reasoning and evidence-based nursing. …”
Get full text

Perirenal fat differs in patients with chronic kidney disease receiving different vitamin D-based treatments: a preliminary study by Ana Checa-Ros, Antonella Locascio, Owahabanun-Joshua Okojie, Pablo Abellán-Galiana, Luis D’Marco

“…Analytical and clinical parameters were evaluated. The PAT thickness was measured in centimeters through a B-mode ultrasound. …”
Get full text

Comparisons of liver transplant from DCD outcomes in high-utilization centers versus low-utilization centers in the US: a systematic review and meta-analysis by Joao Lucas Lima Manzi, Eduarda Saba Oliveira, Sarah Rombach, Vitor Turra, Simone Zaragoza, Yanik Bababekov, Trevor Nydam, Alfred Joseph Tector, Rodrigo Vianna, Phillipe Abreu

“…Heterogeneity among the included studies was evaluated using the I2 test, with I2>40% considered significant, and further explored through influence analysis. …”
Get full text

Identités urbaines et appartenance : les discours des jeunes hommes de Pikine (Sénégal) à propos de leur ville by Sebastian Prothmann

“…De fait, ils se sont dotés d’identités distinctes qu’ils changent en fonction du contexte et, en parallèle, ils ont ressucité leurs sentiments de solidarité, de courage et de fierté au travers de la notion de Pikinité qui leur sert de « norme d’auto-évaluation ». …”
Get full text

The Ottoman Bazaar Through the Eyes of Western Travelers and Poets of the Classical Period by Gülçin Tanrıbuyurdu

“…The presented data highlights the contributions of social history and literature to the evaluation of Ottoman social life and the relationship between literature and society through the parallels found in the observations of travelers and period poets regarding the bazaar.…”
Get full text

The PIKASO trial (Preventing Injured Knees from Osteoarthritis: Severity Outcomes): Rationale and design features for a randomized controlled trial by Cale A. Jacobs, Morgan H. Jones, Jamie E. Collins, Lily M. Waddell, Xiaojuan Li, Carl S. Winalski, Brian Pietrosimone, Virginia Byers Kraus, Miguel Otero, Elizabeth Wellsandt, Laura C. Schmitt, Kurt P. Spindler, Donald D. Anderson, Scott A. Rodeo, Robert A. Magnussen, Brian R. Wolf, Joe M. Hart, Austin V. Stone, Caitlin E. Conley, Yvonne M. Golightly, Gregory D. Myer, Lynn Snyder-Mackler, Martin K. Lotz, Jason S. Kim, Michelle M. McLeod, Janet L. Huebner, Caroline Lisee, Faith Selzer, Jeffrey N. Katz, Kyna Long, Kelly C. Frier, Daniel J. Betensky, David T. Felson, Elena Losina

“…Methods: Preventing Injured Knees from OsteoArthritis: Severity Outcomes (PIKASO) is a multicenter blinded, parallel, two-arm randomized controlled trial of 512 individuals aged 18–45 years undergoing anterior cruciate ligament reconstruction (ACLR). …”
Get full text

Comprehensive Molecular Analysis of Disease-Related Genes as First-Tier Test for Early Diagnosis, Classification, and Management of Patients Affected by Nonsyndromic Ichthyosis by Tiziana Fioretti, Fabrizio Martora, Ilaria De Maggio, Adelaide Ambrosio, Carmelo Piscopo, Sabrina Vallone, Felice Amato, Diego Passaro, Fabio Acquaviva, Francesca Gaudiello, Daniela Di Girolamo, Valeria Maiolo, Federica Zarrilli, Speranza Esposito, Giuseppina Vitiello, Luigi Auricchio, Elena Sammarco, Daniele De Brasi, Roberta Petillo, Antonella Gambale, Fabio Cattaneo, Rosario Ammendola, Paola Nappa, Gabriella Esposito

“…In the attempt to molecularly classify 17 unrelated Italian patients referred with congenital nonsyndromic ichthyosis, we performed massively parallel sequencing of over 50 ichthyosis-related genes. …”
Get full text

A phase 2 trial of CXCR4 antagonism and PD1 inhibition in metastatic pancreatic adenocarcinoma reveals recruitment of T cells but also immunosuppressive macrophages by Katherine M. Bever, Sarah M. Shin, Jennifer N. Durham, Hanfei Qi, Alexei Hernandez, Erin M. Coyne, Nicole E. Gross, Soren Charmsaz, Jayalaxmi Suresh Babu, Diana Carolina Vargas Carvajal, Rohan Verma, Yanyi Sun, Zhehao Zhang, Xuan Yuan, Courtney D. Cannon, Sarah N. Hughes, Sarah Mitchell, Madeline Figlewski, James M. Leatherman, Hao Wang, Robert A. Anders, Elizabeth M. Jaffee, Dung T. Le, Won Jin Ho

“…Blood and tissue biospecimens were collected for correlative analyses. Parallel mouse studies were used to determine potential mechanisms of resistance. …”
Get full text

A Silent Threat in Post-Tuberculosis Patients: Chronic Pulmonary Aspergillosis Survey in Multiple Regions of Indonesia (I-CHROME Study) by Anna Rozaliyani, Findra Setianingrum, Fathiyah Isbaniah, Heidy Agustin, Raden Rara Diah Handayani, Rosamarlina Syahrir, Siti Pratiekauri, Robiatul Adawiyah, Hesti Setiastuti, Mohammad Nizam Erhamza, Retno Ariza S. Soemarwoto, Irvan Medison, Deddy Herman, Avissena Dutha Pratama, Jatu Apridasari, Jani Jane, Soedarsono Soedarsono, Tutik Kusmiati, Mufidatun Hasanah, Diah Adhyaksanti, Winda Sofvina, Ammar A. Hasyim, Chris Kosmidis, David W. Denning

“…Sputum specimens were used in parallel for fungal culture, and radiological evaluations (e.g., chest X-rays or CT scans) were performed to identify typical CPA features such as cavitation and fibrosis. …”
Get full text

Discovery and validation of biomarkers for Parkinson’s disease from human cerebrospinal fluid using mass spectrometry-based proteomics analysisResearch in context by Sungtaek Oh, Jaehun Jung, Jinhyeok Kim, Yura Jang, Catherine C. Bakker, Alexander Y. Pantelyat, Zhen Zhang, Ted M. Dawson, Chan Hyun Na, Liana S. Rosenthal

“…We validated our findings using parallel reaction monitoring mass spectrometry with an independent cohort of CSF samples (80 PD, 80 controls). …”
Get full text

Prospective multicentre randomised clinical trial comparing survival rates, quality of life and nutritional status between advanced gastric cancer patients with different follow-up... by Hyuk-Joon Lee, Moon-Won Yoo, Min-Hee Ryu, Bang Wool Eom, Dong-Hoe Koo, Ji Yeong An, Han Hong Lee, Hyoung-Il Kim, Hoon Hur, Su Mi Kim, Ji-Ho Park, Jae Seok Min, Kyung Won Seo, Sang-Ho Jeong, Oh Jeong, Oh Kyoung Kwon, Seung Wan Ryu, Chang Hak Yoo, Jae Moon Bae, Keun Won Ryu

“…However, there is a lack of evidence with regard to proper surveillance intervals and diagnostic tools. This study aims to evaluate whether frequent surveillance tests have a survival benefit or improve the quality of life in patients who underwent curative resection for advanced gastric cancer.Methods and analysis The STOFOLUP trial is an investigator-initiated, parallel-assigned, multicentre randomised controlled trial involving 16 hospitals in the Republic of Korea. …”
Get full text

Efficacy and safety of combined nebulization of unfractionated heparin, acetylcysteine, budesonide and ipratropium bromide in hospitalised patients with COVID-19 pneumonia: a rando... by Junhui Gong, Naifu Nie, Minrui Jiang, Xinyu Yang, Qinghua Wang, Jia Deng, Jun Kang, Xin Li, Li Zhang, Ying Zhang, Nuo Luo, Xiaoyi Du, Ling Wang, Wei Zhou, Hui Cao, Kunlin Li, Guoqiang Cao, Li Li

“…Methods This single-center, open-label, randomized, parallel-group trial was conducted at a tertiary hospital in China. …”
Get full text

Effects of 12 Weeks of Interval Block Resistance Training Versus Circuit Resistance Training on Body Composition, Performance, and Autonomic Recovery in Adults: Randomized Controll... by Héctor Fuentes-Barría, Raúl Aguilera-Eguía, Juan Maureira-Sánchez, Miguel Alarcón-Rivera, Victor Garrido-Osorio, Olga Patrica López-Soto, Juan Alberto Aristizábal-Hoyos, Lissé Angarita-Davila, Diana Rojas-Gómez, Valmore Bermudez, Cherie Flores-Fernández, Ángel Roco-Videla, Jorge Enrique González-Casanova, Sebastian Urbano-Cerda, Dan Iulian Alexe

“…<b>Methods:</b> A randomized, parallel, double-blind study was conducted with 30 participants assigned to IBRT (n = 15) or CRT (n = 15). …”
Get full text

Children’s Health in London and Luton (CHILL) cohort: a 12-month natural experimental study of the effects of the Ultra Low Emission Zone on children’s travel to school by Christina Xiao, James Scales, Jasmine Chavda, Rosamund E. Dove, Ivelina Tsocheva, Helen E. Wood, Harpal Kalsi, Luke Sartori, Grainne Colligan, Jessica Moon, Esther Lie, Kristian Petrovic, Bill Day, Cheryll Howett, Amanda Keighley, Borislava Mihaylova, Veronica Toffolutti, Jonathan Grigg, Gurch Randhawa, Aziz Sheikh, Monica Fletcher, Ian Mudway, Sean Beevers, W. James Gauderman, Christopher J. Griffiths, Esther van Sluijs, Jenna Panter

“…The Children's Health in London and Luton (CHILL) study evaluates the impact of the ULEZ on children's health. …”
Get full text

Twenty-year experience of examining biopsies of signal lymph nodes in breast cancer by V. F. Semiglazov, P. V. Krivorotko, E. K. Zhiltsova, S. V. Kanaev, E. S. Trufanova, P. I. Krzhivitskiy, A. V. Komyakhov, T. T. Tabagua, K. S. Nikolaev, A. A. Bessonov, V. G. Ivanov, L. P. Gigolaeva, O. A. Ivanova, K. Yu. Zernov, G. A. Dashyan, V. V. Semiglazov, A. S. Emelyanov, E. A. Busko, A. V. Chernaya, A. S. Artemyeva, S. N. Novikov

“…This type of signal LN biopsy had the following diagnostic characteristics: sensitivity was 58.9 %, specificity was 96.2 %, diagnostic accuracy was 87.1 %.In parallel with this study, in 2016 a study of diagnostic accuracy and safety of biopsy of axillary LN after neoadjuvant systemic therapy was started. …”
Get full text

Telephone lifestyle intervention to prevent diabetes in women with recent gestational diabetes mellitus attending the national health system: the LINDA-Brasil clinical trial by Bruce B Duncan, Maria Inês Schmidt, Paula A Bracco, Maria A Nunes, Kadhija A Cherubini, Cristina D Castilhos, Jainara Z Spagiari, Leony M Galliano, Ruben Ladwig, Fabricio B Del Vecchio, Anelita H M Del Vecchio, Michele Drehmer, Adriana Costa Forti, Cristina Façanha, Lenita Zajdenverg, Bianca de Almeida-Pititto, Rosângela Roginski Réa, Patrícia Medici Dualib

“…Objectives To evaluate a postpartum telephone-based lifestyle intervention to prevent diabetes in high-risk women with recent gestational diabetes mellitus (GDM).Design Multicentre parallel randomised clinical trial.Setting Specialised antenatal clinics in the Brazilian National System.Methods Lifestyle Intervention for Diabetes Prevention After Pregnancy compared (1:1) postpartum telephone support for lifestyle changes with conventional care in women with recent GDM at substantial risk for diabetes. …”
Get full text

Efficacy of Chinese Medicine on Postoperative Rehabilitation of Non-small Cell Lung Cancer (NSCLC), a Randomized Controlled Study by Yifeng Gu MD, Yichao Wang MD, Huiling Zhou MD, Ao Qi PhD, Guanjin Wu MM, Jiaqi Li MMed, Congmeng Zhang MMed, Yong Yang MD, Jialin Yao MD, Wenxiao Yang PhD, Lingzi Su MMed, Yi Liu MMed, Xueqi Tian MMed, Jiajun Song MMed, Yabin Gong MD, Xiong Qin MD, Lijing Jiao PhD, Ling Xu PhD

“…Methods: A randomized, parallel-group clinical trial assigned 50 patients to receive Chinese herbal medicine and Liuzijue exercise plus symptomatic treatment, and 49 to symptomatic treatment alone. …”
Get full text

Myocardial dysfunction caused by MyBPC3 P459fs mutation in hypertrophic cardiomyopathy: evidence from multi-omics approaches and super-resolution imaging by Yupeng Wu, Yupeng Wu, Yuzhu Zhang, Yuzhu Zhang, Qirui Zheng, Qirui Zheng, Qiyuan Wang, Qiyuan Wang, Xingyu Fang, Xingyu Fang, Zaihan Zhu, Zaihan Zhu, Jing Lu, Dandan Sun, Dandan Sun

“…HCM patients carrying MyBPC3 P459fs mutation (MyBPC3-P459fs HCMs) and healthy controls (HCs) were evaluated for myocardial function using both conventional and advanced echocardiography. …”
Get full text

Community engagement and chronic viral hepatitis public health interventions: a systematic review, meta-analysis, and complementary crowdsourcing open callResearch in context by Yifan Li, Eneyi Kpokiri, Dalia Elasi, Rongrong Sheng, Keying Wang, Hayley Conyers, Ye Zhang, Danjuma K. Adda, Philippa C. Matthews, Thomas Fitzpatrick, Joseph D. Tucker, Dan Wu

“…To summarize the current state of knowledge on this topic we performed a systematic review and a crowdsourcing open call. Methods: A parallel mixed-methods approach was used in this study. …”
Get full text

Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Itay Tokatly Latzer, Jean-Baptiste Roullet, Wardiya Afshar-Saber, Henry H. C. Lee, Mariarita Bertoldi, Gabrielle E. McGinty, Melissa L. DiBacco, Erland Arning, Melissa Tsuboyama, Alexander Rotenberg, Thomas Opladen, Kathrin Jeltsch, Àngels García-Cazorla, Natalia Juliá-Palacios, K. Michael Gibson, Mustafa Sahin, Phillip L. Pearl

“…This was parallel to laboratory molecular investigations of in vitro GABAergic neurons derived from induced human pluripotent stem cells (hiPSCs) of SSADHD subjects and biochemical analyses performed on a versatile murine model that uses an inducible and reversible rescue strategy allowing on-demand and cell-specific gene therapy. …”
Get full text