Effects of herbal medicines (Eunkyosan/Yin qiao san and Samsoeum/Shen su yin) for treating the common cold: A randomized, placebo-controlled, multicenter clinical trial by Kwan-Il Kim, Minna Hong, Yang-Chun Park, Beom-Joon Lee, Kitae Kim, Byoung Kab Kang, Jun-Yong Choi

“…Methods: A randomized, patient-assessor-blind, placebo-controlled, parallel, and multicenter clinical trial was conducted. …”
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A Phase 3 Randomized Trial Investigating the Safety, Tolerability, and Immunogenicity of V116, an Adult-Specific Pneumococcal Vaccine, Compared with PPSV23, in Adults ≥50 Years of... by Veronika Jotterand, Vinita Jagannath, Andrea Accini Diaz, Juan Diego Velez, Arna Letica, Silvia Narejos Perez, Rebecca Clark, Yoseph Caraco, Olaf Degen, Kyung-Hwa Park, Serhat Ünal, Frederick Wittke, Kimberly Hurtado, Clay Churchill, Ying Zhang, Doreen Fernsler, Jianing Li, Ulrike K. Buchwald, Heather Platt

“…<b>Methods</b>: In this randomized, active comparator-controlled, parallel-group, multisite, double-blind study, participants were randomized 1:1 to receive a single dose of V116 or PPSV23 (NCT05569954). …”
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Effect of fiber-modified kombucha tea on gut microbiota in healthy population: A randomized controlled trial (RCT) by Beatriz Arce-López, Guadalupe X. Bazan, Susana Molina, Maria Carmen Crespo, María García-Beccaria, Silvia Cruz-Gil, Cristina M. Fernández-Díaz, Ana Ramírez de Molina, Ricardo Ramos-Ruiz, Maria Isabel Espinosa-Salinas

“…Methods: A randomized, double-blind, parallel nutritional intervention trial was conducted with 60 participants (58 completed: 42 women and 16 men; mean ± SD age: 39.79 ± 14.58 years). …”
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Weight loss for overweight and obese patients with prostate cancer: a study protocol of a randomised trial comparing clinic-based versus Telehealth delivered EXercise and nutrition... by Robert U Newton, Daniel A Galvão, Dennis R Taaffe, Suzanne K Chambers, David Joseph, Amanda Devine, Colin I Tang, Nigel Spry, Emily Jeffery, Dickon Hayne, Pedro Lopez, P Lyons-Wall, Christine Kudiarasu

“…The purpose of this study was to evaluate the efficacy of telehealth delivered compared with supervised clinic-based delivered exercise and nutrition intervention in overweight/obese patients with prostate cancer.Methods and analysis A single-blinded, two-arm parallel group, non-inferiority randomised trial will be undertaken with 104 overweight/obese men with prostate cancer (body fat percentage ≥25%) randomly allocated in a ratio of 1:1 to a telehealth-delivered, virtually supervised exercise and nutrition programme or a clinic-based, face-to-face supervised exercise and nutrition programme. …”
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Biomechanical and tomographic findings in Brown-McLean syndrome by Jaime Guedes, Rodrigo Vilares-Morgado, Rodrigo Brazuna, Alexandre Costa Neto, Denisse J. Mora-Paez, Marcella Q. Salomão, Fernando Faria-Correia, Renato Ambrósio, Jr.

“…Conclusions and importance: This case series is the first to evaluate the biomechanical and tomographic features of eyes with BMS. …”
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Multimodality local consolidative treatment versus conventional care of advanced lung cancer after first-line systemic anti-cancer treatment: study protocol for the RAMON multicent... by Matthew Evison, Tim Batchelor, Chris A Rogers, Sarah Baos, Elizabeth A Stokes, Rosie Harris, Eric Lim, Chloe Beard, Janette Rawlinson, Nicola Mills, John Conibear, Paulo De Sousa, Thomas Newsom-Davis, Tara Barwick, Leah Fleming

“…The RAMON study (RAdical Management Of Advanced Non-small cell lung cancer) will evaluate the acceptability, effectiveness and cost-effectiveness of LCT versus no LCT after first-line systemic treatment for advanced lung cancer.Methods and analysis RAMON is a pragmatic open multicentre, parallel group, superiority randomised controlled trial. …”
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Methylene Blue Reduces Electroretinogram Distortion and Ganglion Cell Death in a Rat Model of Glaucoma by Ronan Nakamura, Nicolás S. Ciranna, Juan C. Fernández, Rafael Peláez, Álvaro Pérez-Sala, Miriam Bobadilla, Juan J. López-Costa, César F. Loidl, Alfredo Martínez, Manuel Rey-Funes

“…After sacrifice, the number of RGCs and the thickness of the inner retina (IR) were evaluated both in the peripheral and central areas of the retina. …”
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STREAM: a system for tracing radiative transfer and energy balance in heterogeneous surfaces by Tengyuan Fan, Zunjian Bian, Jean-Louis Roujean, Huaguo Huang, Hua Li, Junhua Bai, Biao Cao, Yongming Du, Qing Xiao, Qinhuo Liu

“…The temperature of each voxel is obtained by iterating the radiative transfer and energy balance processes, and the parallel technique on graphics processing units is adopted for high performance. …”
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Scaling up interpersonal psychotherapy training: A pilot randomized controlled trial of digital asynchronous self-directed vs. synchronous group workshop training by Paula Ravitz, Natalie Heeney, Andrea Lawson, Edward McAnanama, Clare Pain, Alex Kiss, Priya Watson, Jan Malat, Sophie Grigoriadis, Simone Vigod, Daisy R. Singla

“…Methods: We developed digital IPT training and evaluated it in a pilot parallel randomized controlled trial. …”
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Nafamostat mesylate augments survival in rats afflicted by exertional heat stroke by Qingwei Lin, Zhuqing Luo, Longping He, Lincui Zhong, Qingbo Zeng, Ye Zhou, Qi Chen, Xingping Deng, Xiaomin Song, Qing Song, Qing Song, Jingchun Song, Jingchun Song

“…ObjectiveTo evaluate the impact of Nafamostat mesylate (NM) in improving survival outcomes among rats subjected to exertional heat stroke.MethodsThis study involved a cohort of 45 specific pathogen-free (SPF) male Sprague Dawley (SD) rats. …”
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Assessment of Early Fuchs Endothelial Corneal Dystrophy and CTG Trinucleotide Expansion Positivity Using Scheimpflug Imaging by Stanley S.J. Poh, MBBS, Kai Yuan Tey, MBBS, Gary S.L. Peh, PhD, Dawn J.H. Neo, MSc, Hla Myint Htoon, PhD, Evan K.L. Lee, Yu Qiang Soh, MBBS, V Vinod Mootha, MD, Jodhbir S. Mehta, PhD

“…Subclinical edema was defined by the presence of ≥2 of the following features: (1) loss of parallel isopachs; (2) displacement of the thinnest point; and (3) focal posterior depression. …”
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Cholesteryl Ester Species but Not Serum Proprotein Convertase Subtilisin/Kexin Type 9 Levels Decline in Male Patients with Active Inflammatory Bowel Disease by Angelika Hettenbach, Tanja Elger, Muriel Huss, Gerhard Liebisch, Marcus Höring, Johanna Loibl, Arne Kandulski, Martina Müller, Hauke Christian Tews, Christa Buechler

“…However, it is not yet known whether these lipids undergo parallel changes in male and female patients with active IBD, nor whether PCSK9 correlates with these lipids and disease severity in either sex. …”
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Establishment of a novel double-antibody sandwich fluorescence microsphere immunochromatographic test strip for rapid detection of swine acute diarrhea syndrome coronavirus (SADS-C... by Xiao Cong, Xiao Cong, Fei Tong, Huizhen Liu, Huizhen Liu, Yujun Zhu, Ningxin Tan, Feng Gu, Huanan Wang, Feng Cong

“…Analytical performance characteristics of the developed FM-ICA were then rigorously evaluated. Finally, clinical validation was conducted by parallel testing of 72 field samples using both FM-ICA and quantitative PCR (qPCR), followed by concordance rate analysis.ResultsFirst, we demonstrated that all four monoclonal antibodies exhibited favorable immunogenicity and specificity. …”
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Inflammatory and metabolic markers mediate the association between urinary metals and non-alcoholic fatty liver disease in U.S. adults: a cross-sectional study by Shu-yue Li, Jia-jie Lv, Jia-jie Lv, Xi-tao Yang, Xi-tao Yang, Cheng-hao Yang, Cheng-hao Yang, Min-yi Yin, Min-yi Yin

“…Further mediation analysis showed that the associations of single metals (mainly Mo, Ba, and Tu) and mixed metals with NAFLD risk were mediated in parallel by the above-mentioned inflammatory and metabolic markers, with the mediating proportions ranging from 16.89% to 69.39% (all P &lt; 0.05). …”
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North of England Women’s Diet and ActivitY - After Breast Cancer (NEWDAY-ABC) intervention in women diagnosed with early oestrogen-positive, HER2-negative breast cancer: a randomis... by C. Wilson, K. Pickering, S. Wane, J. Cohen, C. Huang, M. Northgraves, H. Crank, A. Anderson, H. Cain, R. Copeland, J. Gray, J. Hargreaves, R. J. Q. McNally, J. M. Saxton

“…Methods This was a two-arm, parallel group, randomised controlled feasibility study. …”
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A multi-centred pilot randomised controlled trial of learning through play plus culturally adapted cognitive behaviour therapy for treating postnatal depression in Nigerian women by Dung Ezekiel Jidong, Dung Ezekiel Jidong, Tarela Juliet Ike, Maigari Yusuf Taru, Juliet Yop Pwajok, Charles Nnaemeka Nwoga, John Ezekiel Jidong, Christopher Francis, Shadrack Bitrus Mwankon, Karick Haruna, Zubairu Dagona, Nusrat Husain, Nusrat Husain

“…In Nigeria, there is limited access to evidence-based culturally appropriate care for mothers affected by postnatal depression.MethodsThis study was a multi-centre, two-arm, parallel-group, single-blind, individually randomised controlled trial design adopted to test the feasibility, cultural appropriateness and acceptability of Learning Through Play plus Culturally adapted Cognitive Behaviour Therapy (LTP+CaCBT). …”
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Comparison of the STANDARD M10 C. difficile, Xpert C. difficile, and BD MAX Cdiff assays as confirmatory tests in a two-step algorithm for diagnosing Clostridioides difficile infec... by Hyunseul Choi, Minhee Kang, Sun Ae Yun, Hui-Jin Yu, Eunsang Suh, Tae Yeul Kim, Hee Jae Huh, Nam Yong Lee

“…Two hundred archived stool specimens, previously tested GDH-positive but toxin-negative by EIA, were analyzed in parallel with these NAATs and toxigenic culture, which served as the reference standard. …”
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Cytokine production by the bioptates of invasive non-specific breast carcinoma as a criterion for the use of acetylamide form of synthetic HLDF-6 peptide for differentiation therap... by E. D. Mangazeeva, A. A. Studenikina, E. S. Michailova, D. V. Morozov, S. L. Ryzhikova, Yu. G. Druzhinina, A. V. Proskura, A. P. Bogachuk, V. M. Lipkin, A. I. Autenshlyus

“…Concentrations of TNFa, IFNg, VEGF, G-CSF, GM-CSF, MCP-1, IL-6, IL-8, IL-10, IL-17, IL-18 and IL-1b were determined in parallel in supernatants of bioptates before and after incubation with the studied peptide using the enzyme immunoassay technique. …”
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Oxygenation targets for endovascular therapy in acute ischemic stroke patients (Oxy-TARGET): protocol for a single-centre, open-label randomised controlled trial by Anxin Wang, Zhengfang Hu, Ruquan Han, Fa Liang, Youxuan Wu, Minyu Jian, Xinyan Wang, Yunzhen Wang, Haiyang Liu, Xuan Hou, Kangda Zhang, Zihui Zhang

“…Therefore, we are conducting a randomised controlled trial (RCT) to evaluate the impact of high-concentration oxygen vs low-concentration normobaric oxygen on early neurological function after EVT.Methods and analysis The Oxy-TARGET trial is an ongoing prospective, open-label, parallel-design RCT being conducted at Beijing Tiantan Hospital, Capital Medical University. …”
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Pathogenicity and Bro gene typing of pediatric lower respiratory tract infections with Moraxella catarrhalis in Southwest Shandong, China by Yuhan Xiang, Jian Shi, Liang Han, Chengfan Yang, Shuhua Lu

“…All isolates were confirmed through parallel testing using automated biochemical analyzers and MALDI-TOF mass spectrometry. …”
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