Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study) by Alexia Giovanazzi, Lorenzo Gios, Maria Adalgisa Gentilini, Marina Mastellaro, Patrizia Bartolotta, Lucrezia Nicolussi Giacomaz, Claudio Eccher, Sandro Inchiostro

“…This open-label, parallel-group, 1:1 allocation ratio RCT in which the intervention group used the app for data entry, symptoms questionnaire, communication with healthcare staff and medication recording, while the control group received standard care. …”
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Comparison of middle molecule removal with expanded hemodialysis versus haemodiafiltration among Chinese hemodialysis patients by Liangying Gan, Leyi Gu, Yongchun Ge, Hongli Lin, Yiwen Li, Fengling Chen, Wenge Li, Bihu Gao, Feng Ding, Xinzhou Zhang, Zhenwei Shi, Jiayao Ji, Qiang Yao, Brad Keller, Surupa Sarkar, Li Zuo

“…Background This study aimed to compare uremic toxin removal with expanded hemodialysis against post-dilution online haemodiafiltration therapy in Chinese patients with chronic kidney failure in a single treatment.Methods This randomized, controlled, open-label, parallel, multicenter trial enrolled prevalent patients on hemodialysis. …”
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Effectiveness and safety of a hydrophobic aspheric monofocal intraocular lens with molding process for cataract surgery by Liang-ping Liu, Ying-yan Qin, Qiang Lu, Qiang Wu, Guang-ying Zheng, Yi-yong Qian, Ying-zi Pan, Zhe-ming Wu, Jie-wei Liu, Hong-pei Ji, Xu-dong Huang, Ming-xing Wu

“…Abstract Background To evaluate the effectiveness and safety of a novel hydrophobic aspheric monofocal intraocular lens (IOL) in cataract surgery. …”
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Results of clinical trial in Russia to assess immunological efficacy and safety of meningococcal vaccine (serogroups A, C, Y, W, X) in adults by I. V. Fel'dblyum, S. O. Golodnova, M. Kh. Alyeva, T. M. Repin, E. V. Gorelikova, A. S. Korovkin, E. S. Safonova, A. M. Vlasov

“…The immunological efficacy and safety of the MENVAID® vaccine were assessed in a prospective, comparative, randomized, double-blind clinical trial with parallel groups involving adult volunteers aged 18 to 65 years. …”
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Effect of intermittent theta burst stimulation combined with acoustic startle priming motor training on upper limb motor function and neural plasticity in stroke individuals: study... by Jing Zhang, Yu Chen, Mingzhu Wang, Nan Xia, Jinghong Li, Weiqiang Liang, Yangyang Yin, Linhan Zhai, Qiuxia Wang

“…This study aims to investigate the feasibility of segmentally modulating the cortico-reticular and reticulospinal tracts through ASP and iTBS while evaluating the resulting therapeutic effects.Methods and analysis This is a randomised, blinded interventional trial with three parallel groups. …”
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Longitudinal multimodal MRI analysis of lecanemab treatment in mild cognitive impairment: a pilot study of structural, perfusion, and microstructural changes by Toshiya Takahashi, Dinh Ha Duy Thuy, Shingo Takenaka, Sayaka Ono, Maya Fukui, Yasushi Okada, Tomohiko Asada, Kan Niimi, Kaku Kimura, Akio Ikeda, Ryosuke Takahashi, Riki Matsumoto, Hidenao Fukuyama

“…However, its effects on brain structure, cerebral perfusion, gray matter microstructure and white matter microstructure remain unclear.MethodsThis exploratory longitudinal study aimed to evaluate changes in brain volume, cerebral blood flow (CBF), and diffusion tensor imaging (DTI) measures over a 12-month treatment period in 8 patients with MCI receiving biweekly lecanemab infusions. …”
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Differential diagnostic utilities of combined testing for islet cell antibody, glutamic acid decarboxylase antibody, and tyrosine phosphatase antibody by Alexei V. Timofeev, Igor E. Koltunov, Elena E. Petriaikina, Irina G. Rybkina, Lubov N. Samsonova, Anatoly N. Tiulpakov, Natalia A. Zubkova, Irina G. Kolomina, Evgenia A. Evsjukova, Sergey S. Bukin, Alexey C. Khrushchev

“…All antibodies were tested in parallel in 169 children and adolescents with a new-onset T1D, and in 169 persons without this disease. …”
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Effects of Consuming Pulsed UV Light-Treated <i>Pleurotus citrinopileatus</i> on Vitamin D Nutritional Status in Healthy Adults by Chih-Ching Hsu, Chiao-Ming Chen, Yu-Ming Ju, Yu-Ching Wu, Huei-Mei Hsieh, Shu-Hui Yang, Chien-Tien Su, Te-Chao Fang, Widiastuti Setyaningsih, Sing-Chung Li

“…In a four-week randomized parallel trial, 36 healthy participants were assigned to three groups: a control group, a group consuming 10 g/day PUV-treated PC (PC-10 g), and a group consuming 100 g/day PUV-treated PC (PC-100 g). …”
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Efficiency and effectiveness of intensive multidisciplinary follow-up of patients with stroke/TIA or myocardial infarction compared to usual monitoring: protocol of a pragmatic ran... by Yannick Béjot, Marc Bardou, Mathieu Boulin, Yves Cottin, Maurice Giroud, Anne-Laure Soilly, Gauthier Duloquin, Thibaut Pommier, Gabriel Laurent, Lucie Vadot, Héloïse Adam

“…Patients will be randomised with an allocation ratio of 1:1 in two parallel groups: one group assigned to a multidisciplinary, nurse-based and pharmacist-based 2-year follow-up in association with general practitioners, neurologists and cardiologists versus one group with usual follow-up. …”
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Ethyl acetate extract of Knoxia roxburghii (Rubiaceae) down-regulates ECHDC1, CAMK2D, DDB1, UBA6, BIRC6, and HK1 proteins and ameliorates the symptoms of diabetes mellitus by Xinge Wang, Xinge Wang, Xiaoqiao Tian, Yang Xu, Rong Li, Gusha Qumo, Jingping Li, Niman Bao, Maoru Li, Bin Qiu

“…Proteomics and metabolomics analyses were performed using pancreatic proteins and serum samples, and the proteomics findings were validated via parallel reaction monitoring (PRM).ResultsCompared with the model group, rats in the treatment group showed improved diabetic symptoms. …”
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Reliable detection of CNS lymphoma-derived circulating tumor DNA in cerebrospinal fluid using multi-biomarker NGS profiling: insights from a real-world study by Veronika Navrkalova, Andrea Mareckova, Samuel Hricko, Viera Hrabcakova, Lenka Radova, Vaclav Kubes, Jakub Porc, Tomas Reigl, Sarka Pospisilova, Jana Kotaskova, Andrea Janikova

“…CSF clearly surpasses plasma if applying a routine (non-ultrasensitive) NGS approach and allows for more reliable evidence of CNS involvement than conventional flow cytometry (91% vs. 21%, p < 0.001). Parallel analysis of tumor DNA in both cell-free and cellular DNA from CSF makes the probability of primary or secondary CNS malignancy detection even higher. …”
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Low-temperature nanocubic MgO synthesis from MgCl2·6H2O waste by Patrícia Bodanese Prates, Francielly Roussenq Cesconeto, Francisco Alves Vicente, Tatiana Bendo, Luciana Maccarini Schabbach, Humberto Gracher Riella, Márcio Celso Fredel

“…A similar synthesis process was carried out in parallel with the commercial precursor MgCl2·6H2O (P-com) to compare the products obtained with precursors. …”
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Long-term follow-up of the treatment for severe COVID-19 with qigong exercise and acupressure: A randomized controlled trial by Shuting Liu, Ranran Zhu, Chongjie Yao, Chao Zhan, Jinxiang Wang, Min Fang, Lei Fang

“…The control group received standard therapies.The study was a single-center, parallel, randomized, prospective follow-up study. …”
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Clinical outcomes of nonsurgical root canal treatment using C-root SP combined with different obturation techniques in older patients: a randomized controlled clinical trial by Liping Dong, Jianshe Li, Peng Xue, Suixin Hu, Chen Xu, Lin Wang, Liu Liu, Qiang Luo, Huixia He, Fei Chen

“…Methods This prospective, single-center, single-blind, parallel, randomized clinical trial included 240 patients aged ≥ 60 years. …”
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Oral health awareness, self-care practices, and lived experiences among cancer patients in Ethiopia: a mixed-methods study by Tseganesh Asefa, Winta Tesfaye, Fethiya Seid Hasen, Habtu Kifle Negash, Mihret Getnet, Yihun Tefera Ayenew, Destaye Tirite Gelaw, Tirualem Zeleke Yehuala, Nebebe Demis Baykemagn, Hiwot Tezera Endale

“…Methods A convergent parallel mixed-method study was carried out from February 6 to March 31, 2023, at Tikur Anbessa Specialized Hospital, Ethiopia. …”
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Detection of enoxaparin and argatroban by use of the novel viscoelastic coagulometer ClotPro by Johannes Gratz, Stefan Ulbing, Fabian Schäfer, Stefan Koch, Christoph Dibiasi, Marion Wiegele, Peter Quehenberger, Eva Schaden

“…The ClotPro Russell’s viper venom (RVV)-test and the ClotPro ecarin (ECA)-test clotting time were performed in parallel with conventional coagulation tests (anti-Xa activity, activated partial thromboplastin time, and diluted thrombin time). …”
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ORNIPURAL® as conventional therapy versus mixture of Curcuma longa extract and pomegranate peel extract as homeotherapy in dogs with dexamethasone-induced hepatopathy: clinicolabor... by Arafat Khalphallah, Sabry A. Mousa, Abdulaziz H. Almuhanna, Dalia Hassan, Laila A. Al-Shuraym, Lamya Ahmed Alkeridis, Ebtsam S. Abdel-lah, Mustafa Shukry, Enas A. Abdelhafez, Enas Elmeligy

“…Ultrasonography alone was not enough to evaluate hepatobiliary disorders in canines.…”
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Dementia Moves: protocol for a feasibility study testing a physical rehabilitation program for long-term care residents with moderate to severe dementia by Caitlin McArthur, Niousha Alizadehsaravi, Rebecca Affoo, Karen Cooke, Natalie F. Douglas, Marie Earl, Melanie K. Farlie, Trudy Flynn, Parisa Ghanouni, Susan W. Hunter, Shannan M. Grant, Laura E. Middleton, Elaine Moody, Cheryl Smith, Linda Verlinden, Lori E. Weeks

“…We will use the collected information to inform a definitive parallel cluster randomized controlled trial. Trial registration. …”
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Silk garments plus standard care compared with standard care for treating eczema in children: A randomised, controlled, observer-blind, pragmatic trial (CLOTHES Trial). by Kim S Thomas, Lucy E Bradshaw, Tracey H Sach, Jonathan M Batchelor, Sandra Lawton, Eleanor F Harrison, Rachel H Haines, Amina Ahmed, Hywel C Williams, Taraneh Dean, Nigel P Burrows, Ian Pollock, Joanne Llewellyn, Clare Crang, Jane D Grundy, Juliet Guiness, Andrew Gribbin, Eleanor J Mitchell, Fiona Cowdell, Sara J Brown, Alan A Montgomery, UK Dermatology Clinical Trials Network’s CLOTHES Trial Team

“…<h4>Methods and findings</h4>This was a parallel-group, randomised, controlled, observer-blind trial. …”
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The EmpaTeach intervention for reducing physical violence from teachers to students in Nyarugusu Refugee Camp: A cluster-randomised controlled trial. by Camilla Fabbri, Katherine Rodrigues, Baptiste Leurent, Elizabeth Allen, Mary Qiu, Martin Zuakulu, Dennis Nombo, Michael Kaemingk, Alexandra De Filippo, Gerard Torrats-Espinosa, Elizabeth Shayo, Vivien Barongo, Giulia Greco, Wietse Tol, Karen M Devries

“…<h4>Methods and findings</h4>We conducted a 2-arm cluster-randomised controlled trial with parallel assignment. A complete sample of all 27 primary and secondary schools in Nyarugusu Refugee Camp were approached and agreed to participate in the study. …”
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