Immunogenicity and safety of HepE Hecolin® in chronic hepatitis B patients at clinically stable stage: An open-label study in China by Li Zhang, Qiufen Zhang, Jiaye Liu, Wenlong Wu, Zechun Jiang, Bingyu Yan, Qingfan Cao, Haidong Liu, Huirong Pan, Jingjing Lv, Yi Feng, Fujie Xu, Shoujie Huang, Aiqiang Xu

“…Between 2016 and 2017, an open-label study was conducted to evaluate the immunogenicity and safety of hepatitis E vaccine (HepE) in CHB patients, using healthy adults as parallel controls in China. …”
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Effect of spironolactone on cardiovascular morbidity and mortality in patients with hypertension and glucose metabolism disorders (ESCAM): a study protocol for a pragmatic randomis... by Nanfang Li, Lin Wang, Qin Luo, Jing Hong, Yuanyuan Li, Mengyue Lin, Mulalibieke Heizhati, Jina Yili, Xiaoguang Yao, Qing Zhu

“…Therefore, this study aims to evaluate whether add-on spironolactone (conventional antihypertensive drugs alone vs conventional antihypertensive drugs+spironolactone) can reduce the morbidity and mortality of cardiovascular events in this population.Methods and analysis In this multicentre, randomised, parallel-controlled study, a total of 7140 hypertensive patients aged 45–75 years with GMD and low potassium will be randomised in a 1:1 manner to the control or the spironolactone group (20 mg/day or with a maximum dose of 40 mg). …”
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AIPerf: Automated Machine Learning as an AI-HPC Benchmark by Zhixiang Ren, Yongheng Liu, Tianhui Shi, Lei Xie, Yue Zhou, Jidong Zhai, Youhui Zhang, Yunquan Zhang, Wenguang Chen

“…We implement the algorithms in a highly parallel and flexible way to ensure the efficiency and optimization potential on diverse systems with customizable configurations. …”
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COVID‐19‐Associated Cytotoxic Lesions of the Corpus Callosum in Chinese Patients: A Retrospective Study by Chenyi Wan, Menghua Li, Yanyan Yu, Si Luo, Daojun Hong, Meihong Zhou, Yu Zhu

“…The evaluation included comprehensive analysis of clinical presentations, laboratory findings, and radiological data. …”
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Integrated analyses and a novel nomogram for the prediction of significant fibrosis in patients by Mengxin Lu, Shuai Tao, Xinyan Li, Qunling Yang, Cong Du, Weijia Lin, Shuangshuang Sun, Conglin Zhao, Neng Wang, Qiankun Hu, Yuxian Huang, Qiang Li, Yi Zhang, Liang Chen

“…A nomogram that included the three factors was tabled to evaluate the probability of significant fibrosis occurrence. …”
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Optimization of a CRISPR-Cas9 in vitro protocol for targeting the SIX9 gene of Fusarium oxysporum f.sp. cubense race 1 associated with banana Fusarium wilt by Liliana Villao, Jeffrey Vargas, Nardy Diez, Nardy Diez, Freddy Magdama, Freddy Magdama, Efrén Santos-Ordóñez, Efrén Santos-Ordóñez

“…This protocol will support future studies on banana-Fusarium interaction by identifying candidate genes for disease resistance for the plant, or lack of virulence for the pathogen, by establishing the function of SIX effector proteins and evaluating the fungus’s infection capacity through pathogenicity assays.…”
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Interventions to improve patient safety during the COVID-19 pandemic: a systematic review by Elliott R Haut, Albert W Wu, Renée F Wilson, G Caleb Alexander, Clare Rock, Neelam Dhingra-Kumar, David E Newman-Toker, William Padula, Kathryn McDonald, Rosemary Duncan, Allen Zhang, Katelyn Trigg, Sarah Fisseha, Joyce Black, Irina Papieva

“…Overall, a total of 61 unique articles were included—4 articles were represented across more than one domain.Findings There were few rigorous evaluations of specific interventions to reduce patient harm caused by the pandemic. …”
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Neutrophil-to-Lymphocyte ratio as surrogate for JAK2V617F suppression and event-free survival in polycythemia vera by Tiziano Barbui, Arianna Ghirardi, Victoria Empson, Francesca Fenili, Giuseppe Gaetano Loscocco, Annalisa Condorelli, Alessandra Iurlo, Daniele Cattaneo, Elena Rossi, Valerio De Stefano, Paola Guglielmelli, Christoph Klade, Heinz Gisslinger, Alessandro Rambaldi, Joseph M. Scandura, Alessandro Maria Vannucchi

“…Using data from three of the largest PV clinical trials, we evaluated the effects of PV therapies on NLR and its relationship with molecular response and clinical outcomes. …”
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Scalp Microbiome Dynamics Can Contribute to the Clinical Effect of a Novel Antiseborrheic Dermatitis Shampoo Containing Patented Antifungal Actives: A Randomized Controlled Study by Martine Maître, Sophie Baradat, Mélanie Froliger, Virginie Turlier, Aimée Simcic-Mori, Eléonore Gravier, Camille Géniès, Christophe Lauze, Céline Huyghe, Anaïs Noustens, Sandrine Alvarez-Georges, Rasvan Marinescu, Pascal Reygagne, Sandrine Bessou-Touya, Valérie Mengeaud, Hélène Duplan

“…Methods A two-phase, randomized, controlled study was conducted to evaluate the clinical efficacy of a newly formulated anti-SD shampoo containing two patented antifungal actives and to investigate the associated changes in the scalp microbiota. …”
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Quantifying the Suitability of Biosignals Acquired During Surgery for Multimodal Analysis by Ennio Idrobo-Avila, Gergo Bognar, Dagmar Krefting, Thomas Penzel, Peter Kovacs, Nicolai Spicher

“…As they offer multiple physiological signals measured in parallel, multimodal analysis – which involves their joint analysis – can be conducted and could provide deeper insights than unimodal analysis based on a single signal. …”
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AirQuaNet: A Convolutional Neural Network Model With Multi-Scale Feature Learning and Attention Mechanisms for Air Quality-Based Health Impact Prediction by Sreeni Chadalavada, Suleyman Yaman, Abdulkadir Sengur, Ravinesh C. Deo, Abdul Hafeez-Baig, Tracy Kolbe-Alexander, Niranjana Sampathila, U. Rajendra Acharya

“…The MSCBs employ four parallel 1D convolutional layers with different kernel sizes, enabling the model to extract multi-scale features critical for learning patterns in complex environmental data. …”
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Mozart for the brain - a pilot study on physiological effects of auditive stimulation in patients after aneurysmal subarachnoid hemorrhage by Nicolas Eden, Marius Marc-Daniel Mader, Jan Bremer, Jennifer Sauvigny, Jörn Grensemann, Marlene Fischer, Nils Schweingruber, Jens Gempt, Patrick Czorlich

“…Mozart's Symphony No. 40 in G minor. In parallel, CBFV in the right middle cerebral artery (MCA) was continuously measured using transcranial Doppler (TCD). …”
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Adalimumab vs placebo as add-on to Standard Therapy for autoimmune Uveitis: Tolerability, Effectiveness and cost-effectiveness—a protocol for a randomised controlled trial (ASTUTE... by Chris A Rogers, Andrew Dick, Tunde Peto, Robert Wilson, Pearse A Keane, Alastair K Denniston, Srilakshmi M Sharma, Lucy Culliford, Katie Pike, Sarah Baos, Carlos Pavesio, Sarah Wordsworth, Barnaby Reeves, Annie Folkard, Mae Hazell, Mandy P Y Lui, Nicholas A V Beare

“…The Adalimumab vs placebo as add-on to Standard Therapy for autoimmune Uveitis: Tolerability, Effectiveness and cost-effectiveness (ASTUTE) trial will recruit patients with ANIU who do and do not meet funding criteria and will evaluate the effectiveness and cost-effectiveness of adalimumab versus placebo as an add-on therapy to standard care.Methods and analysis The ASTUTE trial is a multicentre, parallel-group, placebo-controlled, pragmatic randomised controlled trial with a 16-week treatment run-in (TRI). …”
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Psychometric properties of the pain anxiety symptom scale among postoperative patients in Amol, Iran by Hamid Sharif-Nia, Hamid Sharif-Nia, Erika Sivarajan Froelicher, Erika Sivarajan Froelicher, João Marôco, Esmaeil Hoseinzadeh, Sima Hejazi, Sima Hejazi, Reza Fatehi, Poorya Nowrozi, Bita Mohammadi

“…Construct validity was assessed using maximum likelihood exploratory factor analysis with Promax rotation, supported by Horn’s parallel analysis and network analysis to visualize item relationships. …”
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Randomized controlled trial of cognitive behavioral therapy versus health education for sleep disturbance and fatigue following stroke and traumatic brain injury by Lucy Ymer, Adam McKay, Dana Wong, Kate Frencham, Natalie Grima, Monique Roper, Sylvia Nguyen, Jade Murray, Gershon Spitz, Jennie Ponsford

“…Design: Parallel groups randomized controlled trial. Subjects: 126 community dwelling adults with stroke or traumatic brain injury. …”
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Sustainable Placemaking and Thermal Comfort Conditions in Urban Spaces: The Case Study of Avenida dos Aliados and Praça da Liberdade (Porto, Portugal) by Hélder Silva Lopes, Paula C. Remoaldo, Diogo Guedes Vidal, Vítor Ribeiro, Lígia Torres Silva, Javier Martín-Vide

“…Additionally, wind speed was recorded between 1.0 m/s and 2.5 m/s, along with solar radiation levels, which significantly impacted Surface Temperatures (T_surf), reaching up to 38.0 °C in some areas. A parallel subjective survey questionnaire was conducted with 123 participants. …”
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Home-based self-administered transcranial direct current stimulation for women affected by primary dysmenorrhoea in Northeastern Brazil: a protocol study by Thiago Anderson Brito De Araújo, Edson Silva-Filho, Rodrigo Pegado, Tatiana Camila de Lima Alves da Silva, Yvinna Tamiris Rodrigues, Paloma Cristina Alves de Oliveira, Ervinas Bernatavicius, Alexander Anthony Cook, Emilè Radytè, Maria Thereza Micussi

“…This protocol aims to evaluate the effects of home-based self-administered tDCS for pain, premenstrual symptoms, physical performance, quality of life, electroencephalography and patient global impression in women affected by primary dysmenorrhoea.Methods and analysis This is a single-centre, parallel, randomised, double-blinded clinical trial protocol. 40 women affected by primary dysmenorrhoea will be randomised into two groups (active-tDCS or sham-tDCS). …”
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Acupuncture versus cognitive behavioral therapy for anxiety among cancer survivors with insomnia: An exploratory analysis of a randomized clinical trial by Eunbin Kwag, Xiaotong Li, Sheila Garland, Karolina Bryl, Lauren Taylor, Qing S. Li, Lindsay Amann, Jun J. Mao, Kelly M. McConnell

“…Methods: Data were drawn from a dual-center, parallel-group, randomized, comparative effectiveness trial evaluating acupuncture versus CBT-I for insomnia. …”
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Available Transfer Capability Calculation Constrained with Small-Signal Stability Based on Adaptive Gradient Sampling by Peijie Li, Ling Zhu, Xiaoqing Bai, Hua Wei

“…Thus, the computing efficiency is greatly improved owing to the decrease and the parallelization of gradient evaluation, which dominates the computing time of the whole algorithm. …”
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The Chair Plays Trilogy by Edward Bond by Sibel İzmir

“…This review is based on a textual evaluation of Edward Bond’s trilogy The Chair Plays which is a thought-provoking work set in a bleak, dystopian future where individuals struggle against oppressive systems of control. …”
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