Improving and preserving cardiorespiratory fitness, muscle strength and adiposity through a complex lifestyle intervention in community-dwelling older adults with elevated cardiome... by Jonas Johansson, Laila Arnesdatter Hopstock, Sameline Grimsgaard, Trygve Sigvart Deraas, André Henriksen

“…The RESTART (RE-inventing Strategies for healthy Ageing: Recommendations and Tools) randomised controlled trial (RCT) aims to evaluate whether a complex lifestyle intervention can improve and maintain cardiorespiratory fitness, muscle strength and body composition among older adults with elevated cardiometabolic risk.Methods and analysis This is the study protocol for the RESTART trial, a two-arm, open-label, parallel-group RCT conducted in Tromsø, Norway, targeting adults aged 60–75 with obesity, a sedentary lifestyle and high cardiovascular risk. …”
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Extracellular regulated kinase 1/2 signaling is a critical regulator of interleukin-1β-mediated astrocyte tissue inhibitor of metalloproteinase-1 expression. by Jerel Fields, Irma E Cisneros, Kathleen Borgmann, Anuja Ghorpade

“…TIMP-1 and C/EBPβ mRNA and protein expression were evaluated at 12 and 24 h post-treatment, respectively. …”
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Effect of expressive writing on the sexual self-concept in men with multiple sclerosis: a randomized clinical controlled trial by Malihe Mohammadzade Sabbaghi, Leila Amini, Seyed Massood Nabavi, Naiemeh Seyedfatemi, Hamid Haghani

“…Methods This parallel randomized controlled clinical trial conducted on 70 men attending an MS clinic in Tehran in 2022. …”
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PyTomography: A python library for medical image reconstruction by Lucas A. Polson, Roberto Fedrigo, Chenguang Li, Maziar Sabouri, Obed Dzikunu, Shadab Ahamed, Nicolas Karakatsanis, Sara Kurkowska, Peyman Sheikhzadeh, Pedro Esquinas, Arman Rahmim, Carlos Uribe

“…Example use cases demonstrate the software capabilities in parallel hole SPECT and listmode PET imaging. Overall, we have developed and publicly share PyTomography, a highly optimized and user-friendly software for medical image reconstruction, with a class hierarchy that fosters the development of novel imaging applications.…”
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COVID-19 Preventive Behaviors and its Related Beliefs among Health Workers: The Role of Threat and Coping Appraisals by Salman Khazaei, Saeed Bashirian, Ensieh Jenabi, Majid Barati, Akram Karimi-Shahanjarini, Babak Moeini, Forouzan Rezapur-Shahkolai, Manocheher Karami, Mohammad Khazaei, Seyedeh Zeynab Hashemi, Ali Ataei, Zahra Eskandari, Zohreh Fazli

“…The condition of EPPM constructs was evaluated at a relatively favorable level. Also, 46.0% of health personnel were involved in the risk perception process. …”
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Micellar Enhanced Three-Dimensional Excitation-Emission Matrix Fluorescence for Rapid Determination of Antihypertensives in Human Plasma with Aid of Second-Order Calibration Method... by Hai-Yan Fu, He-Dong Li, Chuang Ni, Tian-Ming Yang, Yao Fan, Hao Zhang, Ji Yang, Lin Chen, Yuan-Bin She

“…A highly sensitive three-dimensional excitation-emission fluorescence method was proposed to determine antihypertensives including valsartan and amlodipine besylate in human plasma with the aid of second-order calibration methods based on parallel factor analysis (PARAFAC) and alternating trilinear decomposition (ATLD) algorithms. …”
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Laser‐Induced Structuring of Biocompatible Polymers for the Controlled Orientation of Multinucleated Myotubes by Clarissa Murru, Lucas Duvert, Daniel Ferry, Ahmed Al‐Kattan, Frederique Magdinier, Anne‐Patricia Alloncle, Stefano Testa, Adrien Casanova

“…The resulting surfaces are analyzed using confocal and scanning electron microscopy (SEM). In parallel, the structural and chemical modifications induced by the laser ablation are thoroughly characterized. …”
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Effects of ω-3 PUFAs Supplementation on Myocardial Function and Oxidative Stress Markers in Typical Rett Syndrome by Silvia Maffei, Claudio De Felice, Pierpaolo Cannarile, Silvia Leoncini, Cinzia Signorini, Alessandra Pecorelli, Barbara Montomoli, Stefano Lunghetti, Lucia Ciccoli, Thierry Durand, Roberto Favilli, Joussef Hayek

“…A total of 66 RTT girls were evaluated, half of whom being treated for 12 months with a dietary supplementation of ω-3 PUFAs at high dosage (docosahexaenoic acid ~71.9 ± 13.9 mg/kg b.w.…”
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Combined treatment with mesenchymal stem cells and therapeutic hypothermia for neonatal hypoxic ischemic encephalopathy: a phase 1/2 randomized trial by Kazuko Wada, Akihito Takeuchi, Yoshinori Katayama, Natsuki Ohkawa, Masato Kantake, Kazumichi Fujioka, Toshiya Nishikubo, Yutaka Yamamoto, Yasumasa Yamada, Seiji Yoshimoto, Kiyoaki Sumi, Tomoaki Ioroi, Takeo Mure, Norihisa Wada, Yukimichi Nakano, Naoko Takasao, Kenji Tada, Tatsuyoshi Yamamoto, Hideaki Hirai, Yuji Sato, Hideyuki Ide, Satoshi Kusuda

“…Therefore, we performed a randomized, parallel-group study to compare combined treatment with Temcell and hypothermia versus hypothermia therapy-alone to evaluate the safety and efficacy of Temcell in nHIE patients. …”
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Tunable Magnetic Heating in La_0.51Sr_0.49MnO₃ and La_0.51Dy_0.045Sr_0.445MnO₃ Nanoparticles: Frequency- and... by Mourad Smari, Monica Viorica Moisiuc, Mohammad Y. Al-Haik, Iordana Astefanoaei, Alexandru Stancu, Fedor Shelkovyi, Radel Gimaev, Julia Piashova, Vladimir Zverev, Yousef Haik

“…In parallel, theoretical modeling based on Néel and Brownian relaxation mechanisms was employed to predict SAR behavior as a function of particle size, magnetic anisotropy, and fluid viscosity. …”
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High contamination of Salmonella spp. in raw milk in Ecuador: molecular identification of Salmonella enterica serovars Typhi, Paratyphi, Enteritidis and Typhimurium by Anthony Loor-Giler, Anthony Loor-Giler, Camila Sanchez-Castro, Marcela Robayo-Chico, Byron Puga-Torres, Silvana Santander-Parra, Luis Nuñez, Luis Nuñez

“…For this study, 600 raw milk samples were analyzed using a specific qPCR assay for Salmonella enterica, in parallel, bacterial isolation of the strains was performed according to ISO 6579-1:2017, and serotyped using endpoint PCR assays. …”
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Quantification of Staphylococcal Enterotoxin A Variants at Low Level in Dairy Products by High-Resolution Top-Down Mass Spectrometry by Nina Aveilla, Cécile Feraudet-Tarisse, Dominique Marcé, Abdelhak Fatihi, François Fenaille, Jacques-Antoine Hennekinne, Stéphanie Simon, Yacine Nia, François Becher

“…The protocol was evaluated in liquid and solid dairy products and demonstrated detection limits of 0.5 ng/mL or ng/g in PRM and 1 ng/mL or ng/g in full-scan mode for milk and Roquefort cheese. …”
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Movie‐ and mobile‐therapy without therapist involvment for patients with obsessive–compulsive disorder: Protocol for a randomized controlled trial by Hissei Imai, Yan Luo, Satoshi Funada, Takeshi Hashimoto, Kunitaka Matsuishi, Toko Takamatsu, Yasuo Yoshihara, Yayoi Hiraoka, Yasutaka Mizui, Yu Hayasaka, Nozomi Takeshima, Haruko Fukushima, Kohei Matsuda, Takashi Hashimoto, Toshi A. Furukawa

“…Methods This study is designed as a randomized controlled trial with two parallel group comparison, with assessors blinded to group allocation. …”
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A prediction model of liver fat fraction and presence of non-alcoholic fatty liver disease (NAFLD) among patients with overweight or obesity by Jie Chen, Jiang Yue, Jingjing Fu, Shengyun He, Qianjing Liu, Minglan Yang, Wang Zhang, Hua Xu, Qing Lu, Jing Ma

“…The prevalence of NAFLD in China has exhibited an upward trajectory in parallel with the increasing incidence of obesity over the preceding decade. …”
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Genotyping methods and their contributions to the study of tuberculosis dynamic in Latin America by Yasmin Castillos de Ibrahim das Neves, Ana Julia Reis, Nathália Xavier Maio, Júlia Vianna, João Perdigão, Ivy Bastos Ramis, Pedro Eduardo Almeida da Silva, Andrea von Groll

“…Nonetheless, its application and the knowledge generated depend on the genetic marker evaluated and the detection technologies that have evolved over the years. …”
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Role of <i>Anonychium africanum</i> (Plantae, Fabaceae) in Metal Oxido-Inflammatory Response: Protection Evidence in Gonad of Male Albino Rat by Harrison A. Ozoani, Orish Ebere Orisakwe, Costantino Parisi, Loredana Assisi, Anthonet N. Ezejiofor, Kenneth O. Okolo, Chinna N. Orish, Rubina Vangone, Emidio M. Sivieri, Giulia Guerriero

“…The aim of this study was to evaluate the potential antioxidant, anti-inflammatory, and gonado-protective effects of natural compounds. …”
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Effect of acupuncture on patients with mild cognitive impairment assessed using functional near-infrared spectroscopy on week 12 (close-out): a pilot study protocol by Jung Eun-Sun, Lee Jun-Hwan, Kim Hyun-Tae, Park Sang-Soo, Kim Ji-Eun, Cha Ji-Yoon, Seol In-Chan, Choi Young-Eun, Ho-Ryong Yoo

“…Methods: This study is designed to be a prospective, two-arm, parallel clinical trial involving 24 participants. …”
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Efficacy and safety of nitazoxanide based quadruple regimen as first line therapy for treating Helicobacter pylori infected naïve patients by Amro M Hassan, Muhammad Abdel-Gawad, Maie M Mahmoud, Emad Abdelrazzak, Safwat S Sawy, Mohamed A Sayed, Rasha Maree O Ali, Waleed S EL-Nasser, Mohamed Ahmad Younes Hussein, Mohamed Ramadan Izzaldin, Mohammed F Mohammed

“… Background: Eradication of H. pylori is a challenging issue in many parts of the world including Egypt. Aim: To evaluate the safety and efficacy of adding nitazoxanide as an adjuvant drug to the standard clarithromycin-based regimen, a single-center phase 4 prospective superiority parallel open-label randomized controlled trial was conducted. …”
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Chatbot-delivered structured psychological intervention (SPI-Bot) for teenagers with adolescent idiopathic scoliosis in Hong Kong: protocol for a pilot randomised controlled trial by Yan Li, Jiaying Li, Engle Angela Chan, Teng Zhang, Yuan Cao, Nan Meng, Lu Yu, Jason Pui Yin Cheung, Zhaolong Wu, Dennis Chak Fai Ma

“…Conducted as a single-centre, parallel-group randomised controlled trial, the study aims to assess the feasibility, acceptability and preliminary effectiveness of SPI-Bot. …”
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Study on the Impact of Pipe Installation Height on the Hydraulic Performance of Combined Canal–Pipe Water Conveyance Systems by Yanan Liu, Meijian Bai, Kai Zhang, Baozhong Zhang, Yinong Li, Yuanpeng Wang, Jintao Liu, Hairuo Liu, Yutian He

“…The water depth in the upstream canal remained nearly parallel to the canal bottom. At the junction, the trend of water depth varies under different flow rates. …”
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