A full-spectrum Boswellia serrata extract with enhanced bioavailability, and its co-delivered system with curcumin alleviate pain and stiffness associated with moderate spondylitis... by K. Mamatha, Prathibha Prabhakaran, S. Syam Das, Manu Kanjoormana Aryan, Jestin Thomas

“…ObjectivePain and stiffness at the neck, back, hip, and other joints due to conditions such as spondylitis or spondylosis are significant musculoskeletal concerns globally. The present study evaluated the relative efficacy of a bioavailability enhanced full-spectrum extract of Boswellia serrata Roxb. oleo-gum resin (F-BSE) and its co-delivery system with curcumin (C-BSE) in ameliorating pain and stiffness, in otherwise healthy participants.MethodsThis study adopted a randomized, double-blind, placebo-controlled, three-arm, parallel group comparative design. …”
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Investigation of the Antiviral Activity of Experimental Samples Obtained from the Grass and Roots of Alchemilla vulgaris L. Against Vaccinia Virus and Ectromelia Virus by N. A. Mazurkova, M. A. Protsenko, E. I. Filippova, T. A. Kukushkina, G. I. Vysochina, I. E. Lobanova, O. Yu. Mazurkov, L. N. Shishkina, A. P. Agafonov

“…It was shown that the experimental sample from Alchemilla vulgaris obtained by the method of ethyl acetate extraction from the roots of the studied plant and purified with chloroform contains mainly catechins and leucoanthocyanins (70 %). In parallel, extract from the raw mass of the grass of the plant purified with chloroform and ethanol contains the amount of flavonoids (71 %). …”
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Excavatolide C has oxidative-stress-dependent antiproliferative and apoptotic effects against breast cancer cells by Jun-Ping Shiau, Che-Wei Yang, Wangta Liu, Szu-Yin Yu, Chia-Hung Yen, Fang-Rong Chang, Jyh-Horng Sheu, Hsueh-Wei Chang

“…Methods This study aimed to evaluate the antiproliferative effect and mechanisms (oxidative stress, DNA damage, and apoptosis) caused by EXCC on TNBC and non-TNBC cells in parallel with normal cells. …”
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Improvement in Adenoma Detection Rate with Distal Attachment Device Endo-Wing™-Assisted Colonoscopy: A Randomized Control Trial by Nabil Mohammad Azmi, Prem Kumar Gopal, Muhammad Irfan Abdul Jalal, Mazian Ismail, Farizal Fadzil

“…<b>Methods:</b> This is a single-center, single-blind, parallel-group, randomized, actively controlled, exploratory clinical trial conducted between July 2019 and April 2020. …”
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Effectiveness, Tolerability and Safety of Topical Clobetasol with Oral Hydroxychloroquine versus Topical Clobetasol with NBUVB Phototherapy in Unstable Vitiligo: Investigator Blind... by Dhiman Tarafdar, Indrayudh Sen, Sankha Koley, Biswarup Ray, Pinaki Sarkar, Amrita Sil, Arghyaprasun Ghosh, Nilay K. Das

“…Objectives: The effectiveness, tolerability and safety of narrow-band ultraviolet B (NBUVB)-plus topical clobetasol (group A) versus oral hydroxychloroquine-plus topical clobetasol (0.05%) (group B) were evaluated. Methods: Single-centre, investigator-blind, randomised, active-controlled, parallel-group phase IV trial (CTRI/2019/07/020345) was conducted on unstable vitiligo of either sex. …”
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TCSRNet: a lightweight tobacco leaf curing stage recognition network model by Panzhen Zhao, Panzhen Zhao, Songfeng Wang, Shijiang Duan, Aihua Wang, Lingfeng Meng, Yichong Hu

“…Firstly, the model utilizes an Inception structure with parallel convolutional branches to capture features at different receptive fields, thereby better adapting to the appearance variations of tobacco leaves at different curing stages. …”
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Disease-Associated Dopamine Receptor D2 Variants Exhibit Functional Consequences Depending on Different Heterotrimeric G-Protein Subunit Combinations by Nele Niebrügge, Olga Trovato, Roman Praschberger, Andreas Lieb

“…<b>Methods</b>: To conduct a detailed investigation of the I212F and M345R functional phenotypes, we used the TRansdUcer PATHway (TRUPATH) assay to study heterotrimeric G-protein recruitment and the Parallel Receptorome Expression and Screening via Transcriptional Output (PRESTO-Tango) assay to evaluate transcriptional activation following arrestin translocation for β-arrestin recruitment. …”
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Topical olive oil is not inferior to hyperoxygenated fatty aids to prevent pressure ulcers in high-risk immobilised patients in home care. Results of a multicentre randomised tripl... by Inmaculada Lupiañez-Perez, Shakira Kaknani Uttumchandani, Juan Carlos Morilla-Herrera, Francisco Javier Martin-Santos, Magdalena Cuevas Fernandez-Gallego, Francisco Javier Navarro-Moya, Yolanda Lupiañez-Perez, Eugenio Contreras-Fernandez, Jose Miguel Morales-Asencio

“…Design: Non-inferiority, triple-blind, parallel, multicentre, randomised clinical trial. Scope: Population attending Primary Healthcare Centres in Andalusia (Spain). …”
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Time course of autoantibodies to collagen type I and III in blood serum and skin exudate in atopic dermatitis by I. V. Kibalina, N. N. Tsybikov, E. V. Fefelova, A. V. Kotenko

“…For the first time, the contents of autoantibodies to skin collagen types I and III in the patients with atopic dermatitis we studied in parallel, i.e., at systemic level and in affected skin. …”
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EGFR and K-ras Mutation Analysis in Non-Small Cell Lung Cancer: Comparison of Paraffin Embedded versus Frozen Specimens by Mariëlle I. Gallegos Ruiz, Karijn Floor, Frank Rijmen, Katrien Grünberg, José A Rodriguez, Giuseppe Giaccone

“…In frozen samples, the analysis was carried out using both gDNA and RNA extracted in parallel. Results: Whereas 100% of frozen samples were successfully amplified, the rate of successful PCR amplification in FPE samples was approximately 50%. …”
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Psychometrics and naturalization of nontechnical skills assessment tools in anesthesiology technologist bachelor students in Iran by Fateme Aghebati, Shahnam Sedigh Maroufi, Parisa Moradimajd, Azam Saei, Jamileh Abolghasemi Talkhooncheh

“…Forward–backward translation was applied, and the Persian version was psychometrically evaluated using a questionnaire by an expert panel of 20 anesthesiologists. …”
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PIC2O-Sim: A physics-inspired causality-aware dynamic convolutional neural operator for ultra-fast photonic device time-domain simulation by Pingchuan Ma, Haoyu Yang, Zhengqi Gao, Duane S. Boning, Jiaqi Gu

“…Multiple key techniques have been introduced to mitigate iterative error accumulation while maintaining efficiency advantages during autoregressive field prediction. Extensive evaluations on three challenging photonic device simulation tasks have shown the superiority of our PIC2O-Sim method, showing 51.2% lower roll-out prediction error, 23.5 times fewer parameters than state-of-the-art neural operators, providing 133–310× or 31–89× higher simulation speed than an open-source single-process or eight-process parallel FDTD numerical solver.…”
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The effect of simulation-based breast health education on breast cancer awareness and breast self-examination skills of Afghan refugee women: a randomized controlled trial by Nilgün Kuru Alici, Ayşe Arikan Dönmez, Okşan Aktaş, Zeybek Zeytun

“…Descriptive statistics were used to evaluate the study data, including mean, standard deviation, percentage, and frequency distribution. …”
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The impact of the Change4Life Food Scanner app on children’s diets and parental psychological outcomes: a randomised pilot and feasibility study by Sundus Mahdi, Jim Chilcott, Nicola J. Buckland

“…Methods Adopting a non-blinded parallel trial design, 126 parents of 4-11 year olds were randomly assigned (1:1) through block randomisation sequences into a 3-month intervention consisting of exposure to the Food Scanner app (version 1.6; [n = 62]) or no intervention (n = 64). …”
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Effect of Everyday Life Rehabilitation on recovering quality of life in individuals with serious mental illness in supported accommodation: a pragmatic cluster randomised controlle... by Per Liv, André Sjöberg, Maria Lindström

“…This intervention aims to enhance personal recovery and quality of life by promoting engagement in meaningful everyday activities within real-life contexts.Objective To evaluate the effectiveness of ELR on personal recovery and quality of life among residents with SMI in supported accommodation, compared with treatment-as-usual (TAU).Methods This was a pragmatic, parallel-group, cluster-randomised controlled trial (RCT) (NCT05056415) conducted in Sweden between August 2021 and June 2024. …”
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Inulin supplementation improves some inflammatory indices, clinical outcomes, and quality of life in rheumatoid arthritis patients by Ali Tabatabaeyan, Ani Grigorian, Mansour Salesi, Awat Fiezi, Marzieh Kafeshani

“…The present study investigated the effect of inulin supplementation on pain intensity, clinical outcomes, and quality of life in patients with RA.In a randomized, triple-blind, parallel clinical trial, 60 patients over 18 years of age with RA were randomly assigned to receive either 10 g of inulin or maltodextrin per day for 8 weeks. …”
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Analysis of Microbiome for AP and CRC Discrimination by Alessio Rotelli, Ali Salman, Leandro Di Gloria, Giulia Nannini, Elena Niccolai, Alessio Luschi, Amedeo Amedei, Ernesto Iadanza

“…Subsequently, the synthesised data quality was evaluated using a logistic regression model in parallel with an optimised support vector machine algorithm (polynomial kernel). …”
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Impact of Long-Term Care Insurance on health out-of-pocket expenditure ratios for older adults by Zhe Liu, Ruolin Shi, Lexue Jiang, Fengwen Tang, Zenghui Qiu, Lan Yao

“…We adjusted for socio-demographic and health covariates and conducted robustness and parallel trend tests.ResultsDID results show that LTCI significantly reduced OOPE ratios (coefficient = −0.035, p &lt; 0.01), with dynamic DID confirming a 5.6% reduction in the post-treatment period. …”
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Blood, saliva and urine maresin-1 and malondialdehyde may be useful biomarker in patients with polycystic ovary syndrome: a prospective study by Adem Yavuz, Kader Ugur, Zuhal Karaca Karagoz, Durmus Ayan, Suleyman Aydin

“…Blood, urine and saliva MDA and MaR1 levels were similar and indicated parallel decrease or increase in the PCOS and control groups. …”
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A reach-integrated hydraulic modelling approach for large-scale and real-time inundation mapping by R. Chlumsky, R. Chlumsky, J. R. Craig, J. R. Craig, B. A. Tolson, B. A. Tolson

“…Recent advances in generating flood maps have been made seemingly in parallel between geospatial methods and hydrodynamic models, such as the Height Above Nearest Drainage (HAND) method, hybrid 1D–2D hydrodynamic models, and more efficient computing of 2D models. …”
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