Biologics in Paediatric Crohn's Disease by Oliver Gouldthorpe, Anthony G. Catto-Smith, George Alex

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Disseminated Tuberculosis Mimicking as Crohn’s Disease in a Paediatric Patient by Elizabeth Feenstra, Yentl Driesen, Nicolette Moes, Nathalie Jouret, Koen Vanden Driessche

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Heart failure in paediatric Crohn’s disease patient – extraintestinal manifestation, concomitant disease or iatrogenic effect? by Snehil Swaraj, Erzsébet Szakos, László Ablonczy, Csaba Vilmányi, Ádám Goschler, Áron Cseh

“…However, limited literature exists on this topic in paediatric patients. The primary treatment for Crohn’s disease, the anti-tumor necrosis factor agent infliximab, has been linked to rare but serious cardiovascular complications. …”
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Intestinal tissue levels of anti-TNF alpha, antibodies, and cytokines in paediatric Crohn disease by Vojtech Dotlacil, Stepan Coufal, Tereza Lerchova, Kristyna Zarubova, Barbora Kucerova, Helena Tlaskalova-Hogenova, Miloslav Kverka, Richard Skaba, Jiri Bronsky, Ondrej Hradsky, Michal Rygl

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Adalimumab for endoscopic and histopathological mucosal healing in paediatric patients with moderate to severe Crohn’s disease by Edyta Szymanska, Maciej Dadalski, Wieslawa Grajkowska, Sylwia Szymanska, Maciej Pronicki, Jaroslaw Kierkus

“…Clinical activity of the disease was assessed using the Paediatric Crohn’s Disease Activity Index (PCDAI), and the endoscopic activity was scored using the Simple Endoscopic Score (SES-CD). …”
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Clinical usefulness of the Mucosal Inflammation Noninvasive Index in newly diagnosed paediatric Crohn’s disease patients by Roma B. Herman, Stanisław Pieczarkowski, Paulina Dumnicka, Agnieszka Wyżgowska, Krzysztof Fyderek

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A review of magnetic resonance enterography based Crohn’s disease activity indices in paediatric patients by Roma B. Herman, Paulina Dumnicka, Krzysztof Fyderek

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Enteral Nutrition in Crohn’s Disease: An Underused Therapy by S. Kansal, J. Wagner, C. D. Kirkwood, A. G. Catto-Smith

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Oral exclusive enteral nutrition for induction of clinical remission, mucosal healing, and improvement of nutritional status and growth velocity in children with active Crohn’s dis... by Małgorzata Matuszczyk, Monika Meglicka, Piotr Landowski, Elżbieta Czkwianianc, Beata Sordyl, Edyta Szymańska, Jarosław Kierkuś

Subjects: “…paediatric crohn’s disease…”
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Single-cell microbiota phenotyping reveals distinct disease and therapy-associated signatures in Crohn’s disease by Lisa Budzinski, Gi-Ung Kang, René Riedel, Toni Sempert, Leonie Lietz, René Maier, Janine Büttner, Bettina Bochow, Marcell T. Tordai, Aayushi Shah, Amro Abbas, Tanisha Momtaz, Jannike L. Krause, Robin Kempkens, Katrin Lehman, Gitta A. Heinz, Anne E. Benken, Stefanie Bartsch, Kathleen Necke, Ute Hoffmann, Mir-Farzin Mashreghi, Robert Biesen, Tilmann Kallinich, Tobias Alexander, Bosse Jessen, Carl Weidinger, Britta Siegmund, Andreas Radbruch, Anja Schirbel, Benjamin Moser, Hyun-Dong Chang

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Paediatric Inflammatory Bowel Disease: A Mechanistic Approach to Investigate Exclusive Enteral Nutrition Treatment by Lily Nahidi, Andrew S. Day, Daniel A. Lemberg, Steven T. Leach

“…The inflammatory bowel diseases (IBD) include Crohn’s disease (CD) and ulcerative colitis. …”
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Toward Enteral Nutrition in the Treatment of Pediatric Crohn Disease in Canada: A Workshop to Identify Barriers and Enablers by Johan Van Limbergen, Jennifer Haskett, Anne M Griffiths, Jeff Critch, Hien Huynh, Najma Ahmed, Jennifer C deBruyn, Robert Issenman, Wael El-Matary, Thomas D Walters, Cheryl Kluthe, Marie-Eve Roy, Elizabeth Sheppard, Wallace V Crandall, Stan Cohen, Frank M Ruemmele, Arie Levine, Anthony R Otley

“…The treatment armamentarium in pediatric Crohn disease (CD) is very similar to adult-onset CD with the notable exception of the use of exclusive enteral nutrition (EEN [the administration of a liquid formula diet while excluding normal diet]), which is used more frequently by pediatric gastroenterologists to induce remission. …”
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Highlights in IBD Epidemiology and Its Natural History in the Paediatric Age by Marco Gasparetto, Graziella Guariso

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Anti-Tumor Necrosis Factor-α Use in Pediatric Inflammatory Bowel Disease—Reports from a Romanian Center by Roxana Matran, Andra-Mihaela Diaconu, Andreea Maria Iordache, Irina Dijmărescu, Alexandra Coroleucă, Daniela Păcurar, Cristina Becheanu

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Influence of Genetics, Immunity and the Microbiome on the Prognosis of Inflammatory Bowel Disease (IBD Prognosis Study): the protocol for a Copenhagen IBD Inception Cohort Study by Johan Burisch, Lene Terslev, Mikkel Østergaard, Annette Bøjer Jensen, Frank Krieger Jensen, Flemming Bendtsen, Charlotte Wiell, Mohamed Attauabi, Klaus Theede, Viktoria Fana, Hartwig Roman Siebner, Henrik S Thomsen, Jakob M Møller, Simon Francis Thomsen, Gorm Roager Madsen, Anne Vibeke Wewer, Rune Wilkens, Johan Ilvemark, Nora Vladimirova, Sanja Bay Hansen, Yousef Jesper Wirenfeldt Nielsen, Helene Andrea Sinclair Ingels, Trine Boysen, Jacob T Bjerrum, Christian Jakobsen, Maria Dorn-Rasmussen, Sabine Jansson, Yiqiu Yao, Ewa Anna Burian, Frederik Trier Møller, Kristina Bertl, Andreas Stavropoulos, Jakob B Seidelin

“…Introduction Inflammatory bowel diseases (IBD), encompassing Crohn’s disease and ulcerative colitis, are chronic, inflammatory diseases of the gastrointestinal tract. …”
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Pathobiology of Helicobacter pylori Infection in Children by Robert H Riddell

“…Some diseases, particularly Crohn’s disease, but also human immunodeficiency virus infection, have a negative association with H pylori that appears not to be simply a result of the excess antibiotic therapy that these patients receive. …”
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The Continental Divide: Anti-TNF Use in Pediatric IBD Is Different in North America Compared to Other Parts of the World by Peter C. Church, Jeffrey Hyams, Frank Ruemmele, Lissy de Ridder, Dan Turner, Anne M. Griffiths

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