Liver-specific gene PGRMC1 blocks c-Myc-induced hepatocarcinogenesis through ER stress-independent PERK activation by Fubo Ji, Jianjuan Zhang, Liping Mao, Yaqi Tan, Meihua Ye, Xianglei He, Yongzhi Zhao, Jiaxin Liu, Yan Zhang, Nachuan Zhang, Jiong Shi, Jianing Yan, Xiujun Cai, Bin Zhao, Jianping Jin, Pinglong Xu, Stephanie Roessler, Xin Zheng, Junfang Ji

“…Among the c-Myc- and patient prognosis-associated LSGs, PGRMC1 significantly blocks c-Myc-induced orthotopic HCC formation. The role of PGRMC1 depends on its localization to the endoplasmic reticulum (ER) membrane, where PGRMC1 interacts with PERK through their ER luminal domains. …”
Get full text

V3+ extends the V3 framework to ensure user-centricity and scalability of sensor-based digital health technologies by Jessie P. Bakker, Roland Barge, Jacob Centra, Bryan Cobb, Chas Cota, Christine C. Guo, Bert Hartog, Nathalie Horowicz-Mehler, Elena S. Izmailova, Nikolay V. Manyakov, Samantha McClenahan, Stéphane Motola, Smit Patel, Oana Paun, Marian Schoone, Emre Sezgin, Thomas Switzer, Animesh Tandon, Willem van den Brink, Srinivasan Vairavan, Benjamin Vandendriessche, Bernard Vrijens, Jennifer C. Goldsack

“…Abstract We propose the addition of usability validation to the extended V3 framework, now “V3+”, and describe a pragmatic approach to ensuring that sensor-based digital health technologies can be used optimally at scale by diverse users. Alongside the original V3 components (verification; analytical validation; clinical validation), usability validation will ensure user-centricity of digital measurement tools, paving the way for more inclusive, reliable, and trustworthy digital measures within clinical research and clinical care.…”
Get full text

Tensión Hídrica en la Producción de Pepino Injertado y Cultivado en Suelo y Sustrato by Jesús Tomas Félix-Leyva, Rocío Maricela Peralta-Manjarrez, Alberto Sandoval-Rangel, Adalberto Benavides-Mendoza, Marcelino Cabrera-De la Fuente

Get full text

Vente et rançonnement du butin humain des armées romaines à l’époque des conquêtes (264 av. J.-C. – 117 ap. J.-C.) by Jean-Christophe Robert

Get full text

An Enhanced GC/MS Procedure for the Identification of Proteins in Paint Microsamples by D. Fico, E. Margapoti, A. Pennetta, G. E. De Benedetto

“…Using DMF, the formation of artifacts is limited and the derivatization yield of hydrophilic amino acids such as proline and hydroxyproline has improved, thus making the identification of organic paint media more straightforward. The method has been validated and successfully applied to identify the binder of the sample taken from the pictorial cycle of the 12th century monastery of Santa Maria delle Cerrate (Lecce, Italy), thus highlighting the use of eggs as a binding medium.…”
Get full text

EMOTIONS AND REASONING IN MORAL DECISION MAKING by V. V. Nadurak

“…The work is primarily based on the analysis and synthesis of the main empirical studies of the problem, each of which uses the methods of those sciences in which they were conducted (neurosciences). Originality. In general, the process of moral decision making cannot be described by a single simple model that would see only emotional or rational factor in foundation of this process. …”
Get full text

De-biasing microbiome sequencing data: bacterial morphology-based correction of extraction bias and correlates of chimera formation by Luise Rauer, Amedeo De Tomassi, Christian L. Müller, Claudia Hülpüsch, Claudia Traidl-Hoffmann, Matthias Reiger, Avidan U. Neumann

“…Independent of the extraction protocol, chimera formation increased with higher input cell numbers. Contaminants originated mostly from buffers, and considerable cross-contamination was observed in low-input samples. …”
Get full text

Popular Diets: Intermittent Fasting by Michelle Yavelow, Daniela Mendoza-Rivero, Wendy J. Dahl

Get full text

Value of multi-parameter 123I-MIBG scintigraphy in the differential diagnosis of Parkinson’s disease by Teng Xue, Ying Cui, Ying Kan, Guanyun Wang, Jigang Yang

Get full text

Vegetable Insect Identification and Management - Florida Greenhouse Vegetable Production Handbook, Vol 3 by Susan E. Webb, Robert C. Hochmuth

Get full text

KÜRESEL İNOVASYON ENDEKSİ GÖSTERGELERİ ARASINDAKİ İLİŞKİNİN DEĞERLENDİRİLMESİ - EVALUATION OF THE RELATIONSHIP BETWEEN THE GLOBAL INNOVATION INDEX INDICATORS by Yasemin Hancıoğlu

Get full text

Desiccation as a suitable alternative to cold-storage of phyllosphere samples for DNA-based microbial community analyses by Emily Smenderovac, Karelle Rheault, Marie-Ange Moisan, Caroline Emilson, Élodie Brazeau, Marie-Josée Morency, Patrick Gagné, Vincent Maire, Erik Emilson, Lisa Venier, Christine Martineau

Get full text

Exact Traveling Wave Solutions to the (2 + 1)-Dimensional Jaulent-Miodek Equation by Yongyi Gu, Bingmao Deng, Jianming Lin

Get full text

New Approaches to Fractal–Fractional Bullen’s Inequalities Through Generalized Convexity by Wedad Saleh, Hamid Boulares, Abdelkader Moumen, Hussien Albala, Badreddine Meftah

“…The findings expand the current understanding of fractal–fractional inequalities and offer new insights into the use of local fractional derivatives for analyzing functions with fractional-order properties.…”
Get full text

Evaluation of the structures of the optic nerve and chiasm in patients with skull base tumors using high-resolution MRI by Ekaterina S. Egorova, Valeriia V. Musulevska, Mykola O. Guk, Oksana Y. Skobska

Get full text

Assessment of Risk Tendency of Coal Bursting Pressure in Deep Outburst Seam by Beifang Gu, Longkang Wang, Minbo Zhang

“…In order to analysis the mechanism of coal bursting pressures of deep coal seams and take effective methods to identify, monitor, and control coal bursting pressure, this paper takes 21101 working face of No. 2 coal seam in Dongpang Coal Mine as an example. …”
Get full text

Detection of Pathogenic Serogroups and Virulence Genes in Listeria monocytogenes Strains Isolated from Beef and Beef Products Retailed in Gauteng Province, South Africa, Using Phen... by James Gana, Nomakorinte Gcebe, Rebone Moerane, Yusuf B. Ngoshe, Khomotso Moabelo, Abiodun A. Adesiyun

“…South Africa recently (2017-18) experienced the largest outbreak of human listeriosis in the world caused by L. monocytogenes following the consumption of “polony,” a ready-to-eat meat product. Most (59%) cases originated from Gauteng province, South Africa. As a follow-up study to the outbreak, we used standard bacteriological and molecular methods to determine the prevalence of pathogenic and virulent serogroups of L. monocytogenes in various beef and beef products retailed in Gauteng province, South Africa. …”
Get full text

Measures against the financing of “lone wolves” and small terrorist cells in Europe by Svetoslav YORDANOV

“…The purpose of the publication is to study the financing mechanisms of small independent terrorist organizational units and to propose measures against them. …”
Get full text

Dijital Oyun Reklamlarında Oyuncular Tarafından Üretilen Nefret Söylemleri by Mustafa Merdin

“…Bu reklamlar içerisinden en fazla olumsuz yorum ve beğenmeme sayısı alan 4 farklı türden oyun reklamı örneklem olarak seçilmiştir. Çalışmada MAXQDA programı kullanılarak Youtube üzerinden reklam yorumları ve beğenmeme sayısı çekilmiştir. …”
Get full text

Estimating the Health-Related Quality of Life Benefit of Prophylactic Treatment for COVID-19 in Immunocompromised People: A Multimethod Valuation Study by Katy Gallop, Rebekah Hall, Michael Watt, Daniel Squirrell, Neil Branscombe, Sofie Arnetop, Andrew Lloyd

Get full text