HybTrans: A Molecular Generation and Optimization Model Integrating Protein Pocket Sequence and Structural Information by Chen Yinghao, Liu Hongde, Sun Xiao

“…The model includes a sequence encoding module, a structure encoding module, a small molecule Self-Referencing Embedded Strings (SELFIES) representation module, a fusion decoding module, and a reinforcement learning module. …”
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Intelligent optimization method for hazardous materials transportation routing with multi-mode and multi-criterion collaborative constraints by Fan Chen, Qing Zhu

“…Abstract Hazardous materials transportation route optimization problem is a pressing issue, and multi-dimensional evaluation criteria and diversified transportation modes complicate the problem. …”
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Comparative Analysis of Corneal Wound Healing: Differential Molecular Responses in Tears Following PRK, FS-LASIK, and SMILE Procedures by Dominika Janiszewska-Bil, Beniamin Oskar Grabarek, Anita Lyssek-Boroń, Aleksandra Kiełbasińska, Bernadeta Kuraszewska, Edward Wylęgała, Katarzyna Krysik

“…Background/Objectives: In this study, we aimed to analyze the changes in the expression profiles of selected messenger RNAs (mRNAs) and their encoded proteins in the tears of patients undergoing photorefractive keratectomy (PRK), femtosecond-assisted laser in situ keratomileusis (FS-LASIK), and small-incision lenticule extraction (SMILE) procedures. …”
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A polarisation coding scheme based on an integrated sensing and communication system by Yao Zeng, Luping Xiang, Kun Yang

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Deep TPS-PSO: Hybrid Deep Feature Extraction and Global Optimization for Precise 3D MRI Registration by Gayathri Ramasamy, Tripty Singh, Xiaohui Yuan, Ganesh R Naik

“…The method combines a 3D ResNet encoder to extract volumetric features, a Thin Plate Spline (TPS) model to capture smooth anatomical deformations, and Particle Swarm Optimization (PSO) to estimate transformation parameters efficiently without relying on gradients. …”
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The immunogenic potential of an optimized mRNA lipid nanoparticle formulation carrying sequences from virus and protozoan antigens by Renata S. Fernandes, Gabriela de Assis Burle-Caldas, Sarah Aparecida Rodrigues Sergio, Ana Flávia Bráz, Nathália Pereira da Silva Leite, Milton Pereira, Juliana de Oliveira Silva, Natália Satchiko Hojo-Souza, Bianca de Oliveira, Ana Paula S. Moura Fernandes, Flávio Guimarães da Fonseca, Ricardo Tostes Gazzinelli, Diego dos Santos Ferreira, Santuza M. Ribeiro Teixeira

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Optimizing the use of in vitro transcribed SGK1-mRNA as a therapeutic tool to treat female infertility by Itishri Sahu, Fabienne Engelmann, Brian Weidensee, Harivignesh Ganesan, Sara Y. Brucker, Yogesh Singh, Madhuri S. Salker

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PAPR Reduction in DCO-OFDM Visible Light Communication Systems Using Optimized Odd and Even Sequences Combination by Wei-Wen Hu

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Screening and characterization of soil bacteria for lignin and textile dye effluent bioremediation and optimization using response surface methodology by Sarah Milad, Sarra E. Saleh, Mohammad M. Aboulwafa, Nadia A. Hassouna

“…The optimization experiments resulted in a 2.6-fold increase in dye decolorization capacity after 4 h of incubation with bacterium growth compared to basal conditions and thus indicated a significant reduction in dye decolorization time, accelerating the dye decolorization process and demonstrating enhanced efficiency in ligninolytic enzyme production. …”
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Enhanced Antitumor Immunity Through T Cell Activation with Optimized Tandem Double-OX40L mRNAs by Deng Z, Tian Y, Wang J, Xu Y, Liu Z, Xiao Z, Wang Z, Hu M, Liu R, Yang P

“…This study investigates the use of mRNA-based cancer agents as promising tools to combat and reverse refractory TIME conditions.Methods: We optimized and engineered an mRNA cancer agent encoding double tandemly repeated sequences of the T cell costimulator Oxford 40 ligand (diOX40L). …”
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Optimizing feature selection and deep learning techniques for precise detection of low-rate distributed denial of service (LDDoS) attack by Naeem Ali Al-Shukaili, Miss Laiha M. Kiah, Ismail Ahmedy

“…The misbalancing class features were handled by SMOTE, and k-best features were selected to train the network via recursive elimination of imbalanced features. Feature encoding to train the model with k-best feature is done by label encoder. …”
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Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1. by Sumi Biswas, Matthew D J Dicks, Carole A Long, Edmond J Remarque, Loredana Siani, Stefano Colloca, Matthew G Cottingham, Anthony A Holder, Sarah C Gilbert, Adrian V S Hill, Simon J Draper

“…Here we describe the pre-clinical development and optimization of recombinant human and simian adenoviral (AdHu5 and ChAd63) and orthopoxviral (MVA) vectors encoding transgene inserts for Plasmodium falciparum AMA1 (PfAMA1).…”
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Designing an Urban Air Mobility Corridor Network: A Multi-Objective Optimization Approach Using U-NSGA-III by Zhiyuan Zhang, Yuan Zheng, Chenglong Li, Bo Jiang, Yichao Li

“…Based on a detailed analysis of the obtained Pareto front, a relatively optimal design scheme across three optimization objectives is determined. …”
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Complete genome analysis of the cellulose producing strain Komagataeibacter sucrofermentans SMEG01 by Shuaijun Deng, Lei Wang, Guoqiang Chen, Qilong Qin, Sheng Dong, Haibo Zhang

“…Understanding the genetic background of BC-producing strains through genome sequencing is an effective strategy for optimizing BC synthesis and reducing production costs. …”
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Establishment of potent TCR-T cells specific for cisplatin-resistance related tumor-associated antigen, CLSPN using codon-optimization by Kanta Hori, Shuhei Yamada, Kenji Murata, Haruka Miyata, Yuka Mizue, Aiko Murai, Tomoyuki Minowa, Kenta Sasaki, Naoki Shijubou, Terufumi Kubo, Rena Morita, Serina Tokita, Takayuki Kanaseki, Tomohide Tsukahara, Takashige Abe, Nobuo Shinohara, Yoshihiko Hirohashi, Toshihiko Torigoe

“…We also designed a codon-optimized TCR sequence using GeneArt® GeneOptimizer® (Opt TCR) and compared the TCR-T cells using the original TCR sequence (Ori TCR-T cells) and the codon-optimized TCR sequence (Opt TCR-T cells). …”
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OptiASAR: Optimized Aspect-Based Sentiment Analysis of Reviews With BiLSTM-GRU and NER-BERT in Healthcare Decision-Making by Divanshu Singh, Sunita Shivprakash Barve, Amit Krishna Dwivedi

“…By using the Named Entity Recognition and Bidirectional Encoder Representations from Transformers (NER-BERT) embeddings, the model enhances the representation and contextual comprehension of aspect terms. …”
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A Novel Connected-Components Algorithm for 2D Binarized Images by Costin-Anton Boiangiu, Giorgiana-Violeta Vlăsceanu, Constantin-Eduard Stăniloiu, Nicolae Tarbă, Mihai-Lucian Voncilă

“…We accelerate run detection by using a precomputed 16-bit cache of binary patterns, allowing for fast decoding without relying on bitwise CPU instructions. When compared against other run-length encoded algorithms, such as the Scan-Based Labeling Algorithm or Run-Based Two-Scan, our method achieves up to 35% faster on most real-world datasets. …”
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AMNED: An Efficient Framework for Spiking Neuron Coding in AirComp Federated Learning by Juncheng Ji, Chan-Tong Lam, Ke Wang, Benjamin K. Ng

“…This paper advances ACFL technologies by proposing the Adaptive Memristor Neuron Encoding-Decoding (AMNED) framework for AirComp Federated Learning (ACFL), enabling efficient, privacy-preserving model aggregation optimized for resource-constrained wireless environments. …”
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Impact of Wireless Network Packet Loss on Real-Time Video Streaming Application: A Comparative Study of H.265 and H.266 Codecs by Miran Taha Abdullah, Najmadin Wahid Abdulrahman, Aree Ali Mohammed, Diary Nawzad Hama

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Multi-UAV path planning considering multiple energy consumptions via an improved bee foraging learning particle swarm optimization algorithm by Yuanhang Qi, Haoran Jiang, Gewen Huang, Liang Yang, Fujie Wang, Yunjian Xu

“…In Experiment 2, when compared with four other algorithms, IBFLPSO outperforms them in both the optimal and average solutions. …”
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