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High-risk neuroblastoma stage 4 (NBS4): multi-target inhibitors for c-Src kinases (Csk) and retinoic acid (RA) signalling pathways
Published 2025-05-01“…Research into the altered signalling of RA, which preserves the differentiated state of adult neurons, neural stem cells, and NB cells (SH-SY5Y), is also investigated as a potential multi-target drug. Methods: Using computer-aided technology, including OpenEye Scientific suite, Molegro Virtual docking, Samson suite, and Discovery Studio Visualiser, the results revealed that the receptors for both targets, Csk and RA, share similar amino acid sequencing that ranges from 80–100%, offering the possibility of further testing for multi-target drug use. …”
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Social and economic aspects of treatment of patients with medium (W2) and large (W3) postoperative ventral hernias
Published 2023-04-01“…The control group consisted of 122 patients with postoperative ventral hernias who underwent traditional (open) hernioplasty: using the techniques of onlay – 35 patients, inlay – 12, sublay– 75. …”
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Engaging short film activity that supports learning, science identity, and nature of science comprehension
Published 2025-04-01“…We analyzed quantitative responses using descriptive statistics and open-ended responses using a computational textual analysis method of structured topic modeling. …”
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5704
Assessing Rheology Effects and Pore Space Complexity in Polymer Flow Through Porous Media: A Pore‐Scale Simulation Study
Published 2024-05-01“…This paper introduces a pore‐scale flow simulator based on the OpenFOAM open‐source library, designed to model shear‐thinning flow within porous media. …”
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Creating custom 3D printing material colors using optical modeling of waste plastic
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5706
Adoption of Federated Learning for Healthcare Informatics: Emerging Applications and Future Directions
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No one listens to us, we know this, so we participated: Qualitative evidence from menstruation research during the COVID-19 pandemic
Published 2024-10-01“…Methods: Using computer-assisted qualitative data analysis tools in R, we conducted a thematic analysis on open-ended responses. …”
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Federated and ensemble learning framework with optimized feature selection for heart disease detection
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Tailoring Light–Matter Interactions in Overcoupled Resonator for Biomolecule Recognition and Detection
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Calculation of Flexible Bus-Bars Electrodynamic Stability with Application of Implicit Scheme
Published 2008-10-01“…A numerical method for calculation of open-air substations’ flexible bus-bars dynamic at short-circuit has been improved on equations of a flexible elastic string with application of an implicit scheme. …”
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The competence to deal critically with online information among economics education students and teacher trainees in economics: implications for teacher training
Published 2025-06-01“…In this assessment, the teacher trainees and student teachers were asked to solve open-ended tasks using free Internet research and write short response texts, while also their online behaviour was recorded in situ as Logdata. …”
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A comprehensive Analysis of the Application of GIS and RS Technologies in Flood Prediction and Risk Assessment, with a Focus on Wadi Baysh Dam in the Jazan region. KSA
Published 2024-06-01“…In order to identify the actual Wadi Baysh flood-vulnerable area, this study combined data from remote sensing, the Geographic Information System (GIS) technique, and an Analytical Hierarchy Process (AHP) computation. The investigation was carried out to determine the viability of using remote sensing open-source data,basemap of the study area andArcGIS10.4 software in Wadi Baysh risk management. …”
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Using a web-based application to define the accuracy of diagnostic tests when the gold standard is imperfect.
Published 2013-01-01“…Bayesian latent class models (LCMs) can be helpful under these circumstances, but the necessary analysis requires expertise in computational programming. Here, we describe open-access web-based applications that allow non-experts to apply Bayesian LCMs to their own data sets via a user-friendly interface.…”
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