Cross-sectional survey describing general practitioners’ absolute cardiovascular disease risk assessment practices and their relationship to knowledge, attitudes and beliefs about... by Jason Agostino, Rosemary Korda, Tony Stanton, Kim Greaves, Anita Smith, Kuhan Kunarajah

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Cross-dimensional adaptivity research on a 3D earth observation data cube model by Yu Jinsongdi, Cui Zhanying, Baumann Peter, Tong Ruiju, Wei Dandan, Luo Yuan

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Feasibility and acceptability of contingency management and problem-solving therapy intervention for enhancing alcohol abstinence: a single-arm, mixed methods pilot clinical trial by Jun Ma, Sangeun Lee, Hagar Hallihan, Kathleen M Rospenda, Yichao Wu, Ruth Adomah, Amanda Knepper

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Analytical modelling techniques for enhancing tacrolimus dosing in solid organ transplantation: a systematic review protocol by Manish M Sood, Ayub Akbari, Risa Shorr, Babak Rashidi, Gregory L Hundemer, Amos Buh, Elmira Amooei, Martin M Klamrowski, Christopher R McCudden, James R Green, Stephanie Hoar, Ran Klein

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Exploring the effect of valproic acid levels on patients with epilepsy treated with ketogenic diet: An observational study by Stacey Tarrant, Aurelija Liubauske, Guangyu Zhu, Bo Zhang, Heidi Pfeifer, Ann Paris, Ann M. Bergin, Anna L. Pinto

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Group interventions for amyotrophic lateral sclerosis caregivers in Ireland: a randomised controlled trial protocol by Orla Hardiman, Mark Heverin, Niall Pender, Tom Burke, Jennifer Wilson O'Raghallaigh, Sinead Maguire, Miriam Galvin

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Effect of Electron Donor Groups on Optoelectronic Properties of Betalain Dyes: A DFT Study by Melkizedeck Hiiti Tsere, Rene Costa, Geradius Deogratias, Tatiana Pogrebnaya, Alexander Pogrebnoi, Revocatus Machunda, Ohoud S. Al‐Qurashi, Nuha Wazzan, Nambury Surendra Babu

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Interactions of ST-elevation myocardial infarction, age, and sex and the risk of major adverse cardiovascular events among Chinese adults: a secondary analysis of a single-centre p... by Lin Zhou, Wei Yuan, Cuiping Wang, Yi Liang, Peijing Liu

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Randomised phase II trial of CAPTEM or FOLFIRI as SEcond-line therapy in NEuroendocrine CArcinomas and exploratory analysis of predictive role of PET/CT imaging and biological mark... by Ivan Lolli, Daniele Santini, Rossana Berardi, Giuseppe Badalamenti, Toni Ibrahim, Alfredo Berruti, Alberto Bongiovanni, Chiara Liverani, Sara Pusceddu, Silvana Leo, Giovanni Di Meglio, Stefano Tamberi, Fabio Gelsomino, Francesca Pucci, Francesca Bergamo, Sergio Ricci, Flavia Foca, Stefano Severi, Mauro Cives, Davide Campana, Nicola Silvestris, Angela Buonadonna, Maria Pia Brizzi, Francesca Spada, Sara Cingarlini, Lorenzo Antonuzzo, Davide Pastorelli

“…Results will be widely disseminated via peer-reviewed manuscripts, conference presentations and reports to relevant authorities.The study is currently open in Italy.Trail registration number NCT03387592; Pre-results. …”
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Embedding electronic patient-reported outcome measures into routine care for patients with stage III MELanoma (ePROMs-MEL): protocol for a prospective, longitudinal, mixed-methods... by Serigne Lo, Andrew Spillane, Donna Milne, Robyn Saw, Mbathio Dieng, Iris Bartula, Rachael Morton, Frances Boyle, Julia Lai-Kwon, Kathy Dempsey, Craig Lawn, Thomas Pennington, Skye Dong, Linda Seaman, Dina Saks, Jake Robert Thompson

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Effects of work cessation on cognitive functioning in rural older adults in China: a cross-sectional study based on CHARLS by Xiao-hui Liu, Liang Zhu, Xiao-Yu Li, Wenwen Cheng, Ning-li Zhu, Jia-Xue Li, Sun Jing-Jing, Si-Yu Zhang, Dong-Guang Wang

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Access and use of general and mental health services before and during the COVID-19 pandemic: a systematic review and meta-analysis by Marianna Purgato, Federico Tedeschi, Corrado Barbui, Emiliano Albanese, Eleonora Prina, Beatrice Bano, Camilla Sculco, Monica Bianca Bartucz

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Multimorbidity of cardiometabolic diseases: a cross-sectional study of patterns, clusters and associated risk factors in sub-Saharan Africa by Charles Agyemang, Frederick Wekesah, Calistus Wilunda, Gershim Asiki, Peter Otieno, Richard E Sanya, Welcome Wami

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Evaluation of imaging techniques for early detection of intrathoracic cancers in symptomatic patients in primary care: a systematic review by Fiona M Walter, Jaime L Peters, Richard Neal, Natalia Calanzani, Bogdan Grigore, Wasim Hamad, Lauren Asare

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Multicentre randomised trial of screening with sFlt1/PlGF and planned delivery to prevent pre-eclampsia at term: protocol of the PE37 study by M Timmermans, Josefina Mora, Francesc Figueras, I Casas, H Castillo, Eduard Gratacos, Ladislav Krofta, Francesca Crovetto, Fatima Crispi, Carmina Comas, Alicia Martínez-Varea, Anna Kajdy, Elisa Llurba, Lina Youssef, Juan Luis Delgado, Isabel Puig, Katerina Mackova, Albert Tubau, Aina Ruiz, Antoni Paya, Maria Prat, Frederic Chantraine, Maria Fernanda Lopez-Tinajero, RJ Campos, V Parriego, D Sys, J Modzelewski

“…We hypothesise that a single-step universal screening for term pre-eclampsia based on sFlt1/PlGF ratio at 35–37 weeks followed by planned delivery beyond 37 weeks reduces the prevalence of term pre-eclampsia without increasing the caesarean section rates or worsening the neonatal outcomes.Methods and analysis We propose an open-label randomised clinical trial to evaluate the impact of a screening of term pre-eclampsia with the sFlt-1/PlGF ratio followed by planned delivery in asymptomatic nulliparous women at 35–37 weeks. …”
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Factors influencing the kinetics of MSU crystal depletion measured with dual-energy CT in patients with gout by Tristan Pascart, Victor Laurent, Charlotte Jauffret, Aurore Pacaud, Vincent Ducoulombier, Julie Legrand, Stéphane Verdun, Laurène Norberciak, Jean-François Budzik

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Quantitative EEG signatures in patients with and without epilepsy development after a first seizure by Marysol Segovia‐Oropeza, Erik Hans Ulrich Rauf, Ev‐Christin Heide, Niels K. Focke

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Virological failure and associated factors among patients receiving anti-retroviral therapy in Ethiopia: A systematic review and meta-analysis by Sintayehu Asnakew, Getasew Legas, Amare Kassaw, Tigabu Munye Aytenew, Solomon Demis Kebede, Worku Necho Asferie, Netsanet Ejigu, Binyam Minuye Birhane, Yenework Mulu Tiruneh, Birhanu Mengist Munie, Bekalu Mekonnen Belay, Mengistu Ewunetu, Demewoz Kefale

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Risk factors and prognosis of seizures in adults with community-acquired bacterial meningitis in Denmark: observational cohort studies by Henrik Nielsen, Fredrikke Tove Birgitta Dam Larsen, Christian Thomas Brandt, Lykke larsen, Vibeke Klastrup, Lothar Wiese, Jannik Helweg-Larsen, Birgitte Rønde Hansen, Christian Østergaard Andersen, Jacob Bodilsen, Merete Storgaard, Mette Riber

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Rehabilitation using virtual gaming for Hospital and hOMe-Based training for the Upper limb in acute and subacute Stroke (RHOMBUS II): results of a feasibility randomised controlle... by Cherry Kilbride, Tom Butcher, Meriel Norris, Nana Anokye, Alyson Warland, Karen Baker, Dimitrios A Athanasiou, Guillem Singla-Buxarrais, Jennifer Ryan, Francesca Gowing, Elmar Kal, Carole Pound, Victoria Stewart, Basaam Aweid, Arul Samiyappan

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