Proinflammatory Cytokines IL-6 and TNF-α Increased Telomerase Activity through NF-κB/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells by Seyung S. Chung, Yong Wu, Quincy Okobi, Debbie Adekoya, Mohammad Atefi, Orette Clarke, Pranabananda Dutta, Jaydutt V. Vadgama

“…Combined treatment of IL-6 and TNF-α phosphorylated transcription factors STAT3 in a synergistic manner. …”
Get full text

Autocrine Acetylcholine, Induced by IL-17A via NFκB and ERK1/2 Pathway Activation, Promotes MUC5AC and IL-8 Synthesis in Bronchial Epithelial Cells by Angela Marina Montalbano, Giusy Daniela Albano, Anna Bonanno, Loredana Riccobono, Caterina Di Sano, Maria Ferraro, Liboria Siena, Giulia Anzalone, Rosalia Gagliardo, Michael Paul Pieper, Mark Gjomarkaj, Mirella Profita

“…IL-17A is involved in the IL-8 and Muc5AC production promoting, via NFκB and ERK1/2 pathway activation, the synthesis of ChAT, and the related activity of autocrine ACh in bronchial epithelial cells.…”
Get full text

Virgin coconut oil lessens trichloroacetic acid assault on the stomach and intestine of rats via enhancement of Nrf2 but inhibition of TNF-α, IL1β/NF-kB signalling pathway by OO Oladokun, KO Ajeigbe, MA Adelakun

Subjects: “…Virgin coconut oil…”
Get full text

Modified citrus pectin ameliorates methotrexate-induced hepatic and pulmonary toxicity: role of Nrf2, galectin-3/TLR-4/NF-κB/TNF-α and TGF-β signaling pathways by Randa Ismail, Heba A. Habib, Aliaa F. Anter, Amr Amin, Gehan H. Heeba

Subjects: Get full text

Implementasi Marketing Automation Menggunakan Metode Search Engine Optimization (SEO) On Page dan Off Page pada Website Berbasis Content Management System (CMS) pada PT.... by Reyhan Ivandi, Yusi Tyroni Mursityo, Widhy Hayuhardhika Nugraha Putra

“…Selain itu, peningkatan pada skor authority SEO versi domain authority Moz naik 14 poin. Sedangkan, domain rating versi Ahrefs naik 31 poin. …”
Get full text

Microbiological hazards associated with the use of water in the post‐harvest handling and processing operations of fresh and frozen fruits, vegetables and herbs (ffFVH). Part 5 (Frozen FVH process water management plan) by EFSA Panel on Biological Hazards (BIOHAZ), Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Lieve Herman, Liesbeth Jacxsens, Lapo Mughini‐Gras, Maarten Nauta, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panagiotis Skandamis, Elisabetta Suffredini, Jen Banach, Bin Zhou, Maria Teresa daSilva Felício, Laura Martino, Winy Messens, Angela Botteon

“…A WMP aims to maintain the fit‐for‐purpose microbiological quality of the process water and consists of: (a) identification of microbial hazards and hazardous events linked to process water; (b) establishment of the relationship between microbiological and physico‐chemical parameters; (c) description of preventive measures; (d) description of intervention measures, including their validation, operational monitoring and verification; and (e) record keeping and trend analysis. …”
Get full text

Texture effects in TiB2 coatings electrodeposited from a NaCl-KCl-K2TiF6-NaF-NaBF4 melt at 700 °c by Krendelsberger R., Souto M.F., Sytchev J., Besenhard J.O., Fafilek G., Kronberger H., Nauer G.E.

“…Journal of Mining and Metallurgy. Section B: Metallurgy…”
Get full text

Oncologic oUTcomes of neoadjuvant chemotherapy for obSTructive colon cAncer after steNt decompression (OUTSTAND trial); A study protocol of multicenter non-inferiority randomized controlled trial by Bong-Hyeon Kye, Ji-Hoon Kim, Hyung-Jin Kim, Yoon-Suk Lee, In-Kyu Lee, Won Kyung Kang, Hyeon-Min Cho, Jong-Kyung Park, Chang-Hyeok Ahn, Jae-Im Lee, Seong-Taek Oh, Byung Jo Choi

“…Registration This study is registered on ClinicalTrials.gov Identifier: NCT04889820, registered on May 17, 2021 in clinicaltrials.gov; Protocol ID: XC21MIDI0004.…”
Get full text

Design and fabrication of (Hf0.25Zr0.25Ta0.25Nb0.25)C–SiC ceramics with improved microwave absorbing properties via PDC route by Bin Du, Saidi Wang, Linwei Guo, Yimin Ouyang, Hanwei Cheng, Yajuan Cheng, Tao Zhang

“…As a result, the HEC–SiC-2 composite, containing approximately 21.21 wt% SiC, achieved a minimum reflection loss value (RLmin) of −54.28 dB at 12.39 GHz with a thickness of 3.14 mm. …”
Get full text

Palmitic Acid Induces Production of Proinflammatory Cytokines Interleukin-6, Interleukin-1β, and Tumor Necrosis Factor-α via a NF-κB-Dependent Mechanism in HaCaT Keratinocytes by Bing-rong Zhou, Jia-an Zhang, Qian Zhang, Felicia Permatasari, Yang Xu, Di Wu, Zhi-qiang Yin, Dan Luo

“…Secretion levels of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), NF-κB nuclear translocation, NF-κB activation, Stat3 phosphorylation, and peroxisome proliferator-activated receptor alpha (PPARα) mRNA and protein levels, as well as the cell proliferation ability were measured at the end of the treatment and after 24 hours of recovery. …”
Get full text

Synthesis and protective effect of pyrazole conjugated imidazo[1,2-a]pyrazine derivatives against acute lung injury in sepsis rats via attenuation of NF-κB, oxidative stress, and apoptosis by Zang Binbin, Wang Lihui

Subjects: “…pyrazole-conjugated imidazo[1, 2-a]pyrazine derivatives…”
Get full text

Detecting Freezing of Gait in Parkinson Disease Using Multiple Wearable Sensors Sets During Various Walking Tasks Relative to Medication Conditions (DetectFoG): Protocol for a Prospective Cohort Study by Sébastien Cordillet, Sophie Drapier, Frédérique Leh, Audeline Dumont, Florian Bidet, Isabelle Bonan, Karim Jamal

“…MethodsThis single-center, prospective cohort study (DetectFoG) will include 18 patients with PD. Patients will be fitted with 7 IMUs and will walk a freezing-provoking path under different tasks—“single task,” “dual motor task,” or “dual cognitive task”—and medical conditions corresponding to levodopa medication (“on” or “off”). …”
Get full text

Milled flaxseed-added diets ameliorated hepatic inflammation by reducing gene expression of TLR4/NF-κB pathway and altered gut microbiota in STZ-induced type 1 diabetic mice by Hui Xia, Xiangling Shi, Beijia Zhou, Jing Sui, Chao Yang, Hechun Liu, Ligang Yang, Shaokang Wang, Guiju Sun

Subjects: Get full text

تأثیر زمان آسیاکاری بر ریزساختار و خواص مکانیکی HfB2-ZrB2-TiB2 تف‌جوشی شده به روش پلاسمای جرقه‌ای by اردلان مصدر, زهره بلک

Subjects: Get full text

A cumplicidade entre os comitês de ética em pesquisa em seres humanos e as ações investigatórias by Dartel Ferrari Lima

Subjects: Get full text

Resenha do catálogo da mostra “Judith Lauand – Os anos 50 e a construção da geometria” by Maurício Sapata

“…Nascida na cidade de Pontal, São Paulo, em 1922, Judith Lauand é uma das pioneiras do movimento concretista no Brasil, sendo a única mulher a fazer parte do Grupo Ruptura, um grupo de artistas ligados ao desenvolvimento da arte concreta brasileira que surgiu na segunda metade do século XX. …”
Get full text

RAS, a Pentatricopeptide Repeat Protein, Interacts with OsTRX z to Regulate Chloroplast Gene Transcription and RNA Processing by Zhennan Qiu, Shiyong Wen, Peinan Sun, Dongdong Chen, Chunmiao Wang, Xiliang Song, Liying Xiao, Peiliang Zhang, Dongying Zhao, Cuiping Wen, Peiyan Guan, Xuechu Du, Yinghui Sun, Chenshan Xu, Jian Song

“…This interaction was initially discovered by using a yeast two-hybrid (Y2H) screening technique and was further validated through Y2H and bimolecular fluorescence complementation (BiFC) experiments. …”
Get full text

A técnica multidimensional de ensino e os benefícios proporcionados às startups locais: uma perspectiva dos alunos by Andréa Aparecida da Costa Mineiro, Rita de Cássia Arantes, Luiz Guilherme Rodrigues Antunes, Luiz Marcelo Antonialli

“…Revista Gestão Universitária na América Latina…”
Get full text

Dilema da identidade: os rataplãs do Olodum, políticas de significado e o campo etnopopular no Brasil by Edson Farias

“…These are triangulations through which the group has achieved national and international recognition for its recreational-artistic presentations. We discuss how, in this aesthetical presentations, policies of meaning were engaged with human rights and black cultural identities and expressions as well. …”
Get full text

GRAMSCI, Antonio. Odeio os indiferentes: escritos de 1917. 1. edição ed. São Paulo: Boitempo, 2020. by Tarik Dias Hamdan

“…Pós…”
Get full text